Published in Mutat Res on March 22, 2004
Spontaneous homologous recombination is induced by collapsed replication forks that are caused by endogenous DNA single-strand breaks. Mol Cell Biol (2005) 3.10
PARP3 affects the relative contribution of homologous recombination and nonhomologous end-joining pathways. Nucleic Acids Res (2014) 0.93
Simvastatin induces apoptosis and alters cytoskeleton in endometrial stromal cells. J Clin Endocrinol Metab (2010) 0.91
Induction of homologous recombination following in utero exposure to DNA-damaging agents. DNA Repair (Amst) (2013) 0.76
BLM Deficiency Is Not Associated with Sensitivity to Hydroxyurea-Induced Replication Stress. J Nucleic Acids (2010) 0.75
Oncogene-induced senescence is part of the tumorigenesis barrier imposed by DNA damage checkpoints. Nature (2006) 11.76
DNA repair pathways as targets for cancer therapy. Nat Rev Cancer (2008) 6.69
The cell-cycle checkpoint kinase Chk1 is required for mammalian homologous recombination repair. Nat Cell Biol (2005) 4.62
Inhibition of human Chk1 causes increased initiation of DNA replication, phosphorylation of ATR targets, and DNA breakage. Mol Cell Biol (2005) 4.54
Identification of KIAA1018/FAN1, a DNA repair nuclease recruited to DNA damage by monoubiquitinated FANCD2. Cell (2010) 3.43
PARP is activated at stalled forks to mediate Mre11-dependent replication restart and recombination. EMBO J (2009) 2.99
Defective DNA single-strand break repair in spinocerebellar ataxia with axonal neuropathy-1. Nature (2005) 2.98
Different roles for nonhomologous end joining and homologous recombination following replication arrest in mammalian cells. Mol Cell Biol (2002) 2.73
Methyl methanesulfonate (MMS) produces heat-labile DNA damage but no detectable in vivo DNA double-strand breaks. Nucleic Acids Res (2005) 2.44
Do glucose and lipids exert independent effects on atherosclerotic lesion initiation or progression to advanced plaques? Circ Res (2007) 2.06
Diabetes and diabetes-associated lipid abnormalities have distinct effects on initiation and progression of atherosclerotic lesions. J Clin Invest (2004) 1.73
DNA building blocks: keeping control of manufacture. Crit Rev Biochem Mol Biol (2011) 1.64
Poly (ADP-ribose) polymerase (PARP) is not involved in base excision repair but PARP inhibition traps a single-strand intermediate. Nucleic Acids Res (2010) 1.57
Uptake of analogs of penetratin, Tat(48-60) and oligoarginine in live cells. Biochem Biophys Res Commun (2003) 1.57
UV stalled replication forks restart by re-priming in human fibroblasts. Nucleic Acids Res (2011) 1.51
PTEN deletion in prostate cancer cells does not associate with loss of RAD51 function: implications for radiotherapy and chemotherapy. Clin Cancer Res (2011) 1.46
RNRdb, a curated database of the universal enzyme family ribonucleotide reductase, reveals a high level of misannotation in sequences deposited to Genbank. BMC Genomics (2009) 1.37
The ERCC1/XPF endonuclease is required for completion of homologous recombination at DNA replication forks stalled by inter-strand cross-links. Nucleic Acids Res (2009) 1.30
6-thioguanine selectively kills BRCA2-defective tumors and overcomes PARP inhibitor resistance. Cancer Res (2010) 1.29
Separate domains of Rev1 mediate two modes of DNA damage bypass in mammalian cells. Mol Cell Biol (2009) 1.29
ADAR2 A-->I editing: site selectivity and editing efficiency are separate events. Nucleic Acids Res (2003) 1.25
NrdI essentiality for class Ib ribonucleotide reduction in Streptococcus pyogenes. J Bacteriol (2008) 1.24
NrdR controls differential expression of the Escherichia coli ribonucleotide reductase genes. J Bacteriol (2007) 1.23
Identification of the MMS22L-TONSL complex that promotes homologous recombination. Mol Cell (2010) 1.21
Distribution, sequence homology, and homing of group I introns among T-even-like bacteriophages: evidence for recent transfer of old introns. J Biol Chem (2004) 1.20
Oligomerization status directs overall activity regulation of the Escherichia coli class Ia ribonucleotide reductase. J Biol Chem (2008) 1.18
Methylated DNA causes a physical block to replication forks independently of damage signalling, O(6)-methylguanine or DNA single-strand breaks and results in DNA damage. J Mol Biol (2010) 1.16
A method to monitor replication fork progression in mammalian cells: nucleotide excision repair enhances and homologous recombination delays elongation along damaged DNA. Nucleic Acids Res (2004) 1.14
Efficient growth inhibition of Bacillus anthracis by knocking out the ribonucleotide reductase tyrosyl radical. Proc Natl Acad Sci U S A (2005) 1.11
The role of RAD51 in etoposide (VP16) resistance in small cell lung cancer. Int J Cancer (2003) 1.09
Ribonucleotide reduction - horizontal transfer of a required function spans all three domains. BMC Evol Biol (2010) 1.09
SegH and Hef: two novel homing endonucleases whose genes replace the mobC and mobE genes in several T4-related phages. Nucleic Acids Res (2005) 1.08
Crystal structure of the di-iron/radical protein of ribonucleotide reductase from Corynebacterium ammoniagenes. Biochemistry (2002) 1.08
Homologous recombination repair is essential for repair of vosaroxin-induced DNA double-strand breaks. Oncotarget (2010) 1.06
Insertion of a homing endonuclease creates a genes-in-pieces ribonucleotide reductase that retains function. Proc Natl Acad Sci U S A (2007) 1.05
Two proteins mediate class II ribonucleotide reductase activity in Pseudomonas aeruginosa: expression and transcriptional analysis of the aerobic enzymes. J Biol Chem (2005) 1.04
Number of spikes in climbing fibers determines the direction of cerebellar learning. J Neurosci (2013) 1.01
A method to find tissue-specific novel sites of selective adenosine deamination. Nucleic Acids Res (2005) 1.00
Ribonucleotide reductase modularity: Atypical duplication of the ATP-cone domain in Pseudomonas aeruginosa. J Biol Chem (2006) 0.99
NrdH-redoxin protein mediates high enzyme activity in manganese-reconstituted ribonucleotide reductase from Bacillus anthracis. J Biol Chem (2011) 0.98
DNA repair rate and etoposide (VP16) resistance of tumor cell subpopulations derived from a single human small cell lung cancer. Lung Cancer (2003) 0.97
Effects of one bout of endurance exercise on the expression of myogenin in human quadriceps muscle. Histochem Cell Biol (2004) 0.97
Classical conditioning of motor responses: what is the learning mechanism? Neural Netw (2013) 0.96
Cell studies of the DNA bis-intercalator Delta-Delta [mu-C4(cpdppz)(2)-(phen)(4)Ru(2)](4+): toxic effects and properties as a light emitting DNA probe in V79 Chinese hamster cells. Mutagenesis (2002) 0.95
The evolution of the ribonucleotide reductases: much ado about oxygen. J Mol Evol (2002) 0.95
High-resolution crystal structures of the flavoprotein NrdI in oxidized and reduced states--an unusual flavodoxin. Structural biology. FEBS J (2010) 0.94
Use of structural phylogenetic networks for classification of the ferritin-like superfamily. J Biol Chem (2012) 0.94
Targeting protein for xenopus kinesin-like protein 2 (TPX2) regulates γ-histone 2AX (γ-H2AX) levels upon ionizing radiation. J Biol Chem (2012) 0.93
Bidirectional plasticity of Purkinje cells matches temporal features of learning. J Neurosci (2014) 0.92
Bacillus anthracis thioredoxin systems, characterization and role as electron donors for ribonucleotide reductase. J Biol Chem (2012) 0.92
Manganese lipoxygenase oxidizes bis-allylic hydroperoxides and octadecenoic acids by different mechanisms. Biochim Biophys Acta (2010) 0.91
Both replication bypass fidelity and repair efficiency influence the yield of mutations per target dose in intact mammalian cells induced by benzo[a]pyrene-diol-epoxide and dibenzo[a,l]pyrene-diol-epoxide. DNA Repair (Amst) (2008) 0.90
Chapter 28: Future perspective in peripheral nerve reconstruction. Int Rev Neurobiol (2009) 0.89
Enhancement by effectors and substrate nucleotides of R1-R2 interactions in Escherichia coli class Ia ribonucleotide reductase. J Biol Chem (2004) 0.89
Self-splicing of the bacteriophage T4 group I introns requires efficient translation of the pre-mRNA in vivo and correlates with the growth state of the infected bacterium. J Bacteriol (2006) 0.89
In vivo assay for low-activity mutant forms of Escherichia coli ribonucleotide reductase. J Bacteriol (2003) 0.89
Mutant R1 proteins from Escherichia coli class Ia ribonucleotide reductase with altered responses to dATP inhibition. J Biol Chem (2004) 0.88
A functional homing endonuclease in the Bacillus anthracis nrdE group I intron. J Bacteriol (2007) 0.88
Neurite guidance on protein micropatterns generated by a piezoelectric microdispenser. Biomaterials (2006) 0.87
Gold- and silver nanoparticles affect the growth characteristics of human embryonic neural precursor cells. PLoS One (2013) 0.86
Protein thiyl radicals directly observed by EPR spectroscopy. Arch Biochem Biophys (2002) 0.86
A metagenomics transect into the deepest point of the Baltic Sea reveals clear stratification of microbial functional capacities. PLoS One (2013) 0.86
Discovery of antimicrobial ribonucleotide reductase inhibitors by screening in microwell format. Proc Natl Acad Sci U S A (2012) 0.85
A finite element analysis of stress distribution in bone tissue surrounding uncoupled or splinted dental implants. Clin Implant Dent Relat Res (2008) 0.85
The conserved active site asparagine in class I ribonucleotide reductase is essential for catalysis. J Biol Chem (2001) 0.85
Synergistic interactions between camptothecin and EGFR or RAC1 inhibitors and between imatinib and Notch signaling or RAC1 inhibitors in glioblastoma cell lines. Cancer Chemother Pharmacol (2013) 0.85
Chemical structure determination of DNA bases modified by active metabolites of lucidin-3-O-primeveroside. Chem Res Toxicol (2010) 0.85
Efficient radical scavenging ability of artepillin C, a major component of Brazilian propolis, and the mechanism. Org Biomol Chem (2003) 0.85
Lysine-specific demethylase 1-selective inactivators: protein-targeted drug delivery mechanism. Angew Chem Int Ed Engl (2013) 0.85
Assessing relative bioactivity of chemical substances using quantitative molecular network topology analysis. J Chem Inf Model (2012) 0.84
Subunit and small-molecule interaction of ribonucleotide reductases via surface plasmon resonance biosensor analyses. Protein Eng Des Sel (2010) 0.84
DNA interstrand crosslinks induce a potent replication block followed by formation and repair of double strand breaks in intact mammalian cells. DNA Repair (Amst) (2012) 0.84
Biological actions of formoterol isomers. Pulm Pharmacol Ther (2002) 0.84
Antibacterial activity of radical scavengers against class Ib ribonucleotide reductase from Bacillus anthracis. Biol Chem (2010) 0.84
Nucleotide-dependent formation of catalytically competent dimers from engineered monomeric ribonucleotide reductase protein R1. J Biol Chem (2005) 0.84
Activation of the human Ah receptor by aza-polycyclic aromatic hydrocarbons and their halogenated derivatives. Biol Pharm Bull (2003) 0.84
Photoinduced nitric oxide release from a hindered nitrobenzene derivative by two-photon excitation. J Am Chem Soc (2009) 0.84
Thiols in redox mechanism of ribonucleotide reductase. Methods Enzymol (2002) 0.84
CK2 phosphorylation of XRCC1 facilitates dissociation from DNA and single-strand break formation during base excision repair. DNA Repair (Amst) (2011) 0.83
DNA repair and replication influence the number of mutations per adduct of polycyclic aromatic hydrocarbons in mammalian cells. DNA Repair (Amst) (2011) 0.83
Structural and mutational studies of the carboxylate cluster in iron-free ribonucleotide reductase R2. Biochemistry (2004) 0.83
The 4'-hydroxy group is responsible for the in vitro cytogenetic activity of resveratrol. Mutat Res (2002) 0.83
Tomato juice intake suppressed serum concentration of 8-oxodG after extensive physical activity. Nutr J (2012) 0.83
Cyclobutane pyrimidine dimers do not fully explain the mutagenicity induced by UVA in Chinese hamster cells. Mutat Res (2008) 0.83