Senescence-associated changes in respiration and oxidative phosphorylation in primary human fibroblasts.

PubWeight™: 1.38‹?› | Rank: Top 10%

🔗 View Article (PMC 1224220)

Published in Biochem J on June 15, 2004

Authors

Eveline Hutter1, Kathrin Renner, Gerald Pfister, Petra Stöckl, Pidder Jansen-Dürr, Erich Gnaiger

Author Affiliations

1: Abteilung Molekular-und Zellbiologie, Institut für Biomedizinische Alternsforschung der Osterreichischen Akademie der Wissenschaften, Rennweg 10, A-6020 Innsbruck, Austria.

Articles citing this

Mitochondrial dysfunction accounts for the stochastic heterogeneity in telomere-dependent senescence. PLoS Biol (2007) 2.78

Cellular senescence and its effector programs. Genes Dev (2014) 2.37

DNA damage in telomeres and mitochondria during cellular senescence: is there a connection? Nucleic Acids Res (2007) 1.60

Mitochondrial oxidative stress caused by Sod2 deficiency promotes cellular senescence and aging phenotypes in the skin. Aging (Albany NY) (2012) 1.57

Decreasing mitochondrial fission diminishes vascular smooth muscle cell migration and ameliorates intimal hyperplasia. Cardiovasc Res (2015) 1.50

mtRF1a is a human mitochondrial translation release factor decoding the major termination codons UAA and UAG. Mol Cell (2007) 1.33

Elevated CO(2) levels cause mitochondrial dysfunction and impair cell proliferation. J Biol Chem (2011) 1.24

Cystathionine beta-synthase (CBS) contributes to advanced ovarian cancer progression and drug resistance. PLoS One (2013) 1.10

Targeting of the cytosolic poly(A) binding protein PABPC1 to mitochondria causes mitochondrial translation inhibition. Nucleic Acids Res (2010) 1.07

The NADPH oxidase Nox4 restricts the replicative lifespan of human endothelial cells. Biochem J (2009) 1.03

Targeting of NAD metabolism in pancreatic cancer cells: potential novel therapy for pancreatic tumors. Clin Cancer Res (2013) 1.00

Estrogen-related receptor alpha modulates lactate dehydrogenase activity in thyroid tumors. PLoS One (2013) 1.00

Mitochondrial bioenergetic adaptations of breast cancer cells to aglycemia and hypoxia. J Bioenerg Biomembr (2010) 0.96

Reduced axonal transport in Parkinson's disease cybrid neurites is restored by light therapy. Mol Neurodegener (2009) 0.95

Cellular senescence: unravelling complexity. Age (Dordr) (2009) 0.93

The impact of age-related dysregulation of the angiotensin system on mitochondrial redox balance. Front Physiol (2014) 0.89

Nitric oxide protects the heart from ischemia-induced apoptosis and mitochondrial damage via protein kinase G mediated blockage of permeability transition and cytochrome c release. J Biomed Sci (2009) 0.88

Mitochondrial oxidative phosphorylation compensation may preserve vision in patients with OPA1-linked autosomal dominant optic atrophy. PLoS One (2011) 0.87

Unique cellular and mitochondrial defects mediate FK506-induced islet β-cell dysfunction. Transplantation (2011) 0.87

Telomeres, oxidative stress and inflammatory factors: partners in cellular senescence? Longev Healthspan (2014) 0.87

Energy metabolism in H460 lung cancer cells: effects of histone deacetylase inhibitors. PLoS One (2011) 0.87

Cellular senescence and protein degradation: breaking down cancer. Cell Cycle (2014) 0.85

A stochastic step model of replicative senescence explains ROS production rate in ageing cell populations. PLoS One (2012) 0.84

Sod2 haploinsufficiency does not accelerate aging of telomere dysfunctional mice. Aging (Albany NY) (2009) 0.83

Mitochondrial bioenergetic alterations in mouse neuroblastoma cells infected with Sindbis virus: implications to viral replication and neuronal death. PLoS One (2012) 0.82

Identification of microRNA-mRNA functional interactions in UVB-induced senescence of human diploid fibroblasts. BMC Genomics (2013) 0.81

Glucocorticoid modulation of mitochondrial function in hepatoma cells requires the mitochondrial fission protein Drp1. Antioxid Redox Signal (2012) 0.81

Methionine restriction slows down senescence in human diploid fibroblasts. Aging Cell (2014) 0.81

Endogenous myoglobin in breast cancer is hypoxia-inducible by alternative transcription and functions to impair mitochondrial activity: a role in tumor suppression? J Biol Chem (2011) 0.81

Mitoenergetic Dysfunction Triggers a Rapid Compensatory Increase in Steady-State Glucose Flux. Biophys J (2015) 0.78

Cystathionine beta synthase modulates senescence of human endothelial cells. Aging (Albany NY) (2012) 0.78

Mitochondrial dysfunction in long-term neuronal cultures mimics changes with aging. Med Sci Monit (2011) 0.78

Vascular and hepatic impact of short-term intermittent hypoxia in a mouse model of metabolic syndrome. PLoS One (2015) 0.78

Comparative bioenergetic study of neuronal and muscle mitochondria during aging. Free Radic Biol Med (2013) 0.76

FAH domain containing protein 1 (FAHD-1) is required for mitochondrial function and locomotion activity in C. elegans. PLoS One (2015) 0.76

AK2 deficiency compromises the mitochondrial energy metabolism required for differentiation of human neutrophil and lymphoid lineages. Cell Death Dis (2015) 0.76

Impaired energy metabolism of senescent muscle satellite cells is associated with oxidative modifications of glycolytic enzymes. Aging (Albany NY) (2016) 0.75

Targeted deletion of Crif1 in mouse epidermis impairs skin homeostasis and hair morphogenesis. Sci Rep (2017) 0.75

Pro- and Antioxidant Functions of the Peroxisome-Mitochondria Connection and Its Impact on Aging and Disease. Oxid Med Cell Longev (2017) 0.75

Articles cited by this

A biomarker that identifies senescent human cells in culture and in aging skin in vivo. Proc Natl Acad Sci U S A (1995) 32.89

Aging: a theory based on free radical and radiation chemistry. J Gerontol (1956) 20.39

Molecular characterization of mitochondrial apoptosis-inducing factor. Nature (1999) 14.41

Cellular energy utilization and molecular origin of standard metabolic rate in mammals. Physiol Rev (1997) 4.76

Molecular and cytogenetic analysis of immortalized human primary keratinocytes obtained after transfection with human papillomavirus type 16 DNA. Oncogene (1987) 4.02

JC-1, but not DiOC6(3) or rhodamine 123, is a reliable fluorescent probe to assess delta psi changes in intact cells: implications for studies on mitochondrial functionality during apoptosis. FEBS Lett (1997) 3.41

Mitochondria and cell death. Mechanistic aspects and methodological issues. Eur J Biochem (1999) 3.07

Increased mitochondrial oxidative stress in the Sod2 (+/-) mouse results in the age-related decline of mitochondrial function culminating in increased apoptosis. Proc Natl Acad Sci U S A (2001) 2.63

Evaluation of fluorescent dyes for the detection of mitochondrial membrane potential changes in cultured cardiomyocytes. Cardiovasc Res (2000) 2.22

Mitochondrial adenine nucleotide translocase is modified oxidatively during aging. Proc Natl Acad Sci U S A (1998) 2.15

The voltage sensor of the mitochondrial permeability transition pore is tuned by the oxidation-reduction state of vicinal thiols. Increase of the gating potential by oxidants and its reversal by reducing agents. J Biol Chem (1994) 2.14

Superoxide activates mitochondrial uncoupling protein 2 from the matrix side. Studies using targeted antioxidants. J Biol Chem (2002) 2.04

Increased AMP:ATP ratio and AMP-activated protein kinase activity during cellular senescence linked to reduced HuR function. J Biol Chem (2003) 1.95

The mitochondrial theory of aging: dead or alive? Aging Cell (2003) 1.76

Bioenergetics at low oxygen: dependence of respiration and phosphorylation on oxygen and adenosine diphosphate supply. Respir Physiol (2001) 1.72

A mitochondrial paradigm for degenerative diseases and ageing. Novartis Found Symp (2001) 1.63

Mitochondrial oxidative damage, hydrogen peroxide release, and aging. Free Radic Biol Med (1994) 1.61

Induction by leptin of uncoupling protein-2 and enzymes of fatty acid oxidation. Proc Natl Acad Sci U S A (1997) 1.59

Origins of G1 arrest in senescent human fibroblasts. Bioessays (1995) 1.44

Oxidative damage to mitochondria and aging. Exp Gerontol (2001) 1.35

Telomeres and telomerase: implications for cancer and aging. Radiat Res (2001) 1.34

Metabolic analysis of senescent human fibroblasts reveals a role for AMP in cellular senescence. Biochem J (2003) 1.24

High-voltage electron microscopy of human diploid fibroblasts during ageing in vitro. Morphometric analysis of mitochondria. Exp Cell Res (1984) 1.20

Evaluation of mitochondrial respiratory function in small biopsies of liver. Anal Biochem (2002) 1.17

Tetramethyl rhodamine methyl ester (TMRM) is suitable for cytofluorometric measurements of mitochondrial membrane potential in cells treated with digitonin. Biosci Rep (1999) 1.17

Mitochondrial enzyme-deficient hippocampal neurons and choroidal cells in AD. Neurology (2001) 1.17

Uncoupling proteins: their roles in adaptive thermogenesis and substrate metabolism reconsidered. Br J Nutr (2001) 1.14

Changes of mitochondrial respiration, mitochondrial content and cell size after induction of apoptosis in leukemia cells. Biochim Biophys Acta (2003) 1.08

Aerobic glycolysis by proliferating cells: protection against oxidative stress at the expense of energy yield. J Bioenerg Biomembr (1997) 1.05

Status of mitochondria in living human fibroblasts during growth and senescence in vitro: use of the laser dye rhodamine 123. J Cell Biol (1981) 1.02

Aging enhances the activation of the permeability transition pore in mitochondria. Biochem Biophys Res Commun (2000) 1.01

Oxygen dependence of respiration in coupled and uncoupled endothelial cells. Am J Physiol (1996) 1.01

Integrating epithelial cancer, aging stroma and cellular senescence. Adv Gerontol (2003) 0.97

Marked aging-related decline in efficiency of oxidative phosphorylation in human skin fibroblasts. FASEB J (2003) 0.95

The effects of dietary restriction on mitochondrial dysfunction in aging. Ann N Y Acad Sci (1998) 0.94

Separation of two subpopulations of old human fibroblasts by mitochondria (rhodamine 123) fluorescence. Growth Dev Aging (1991) 0.93

Energy metabolism in cultured human fibroblasts during aging in vitro. J Cell Physiol (1982) 0.93

Biphasic oxygen kinetics of cellular respiration and linear oxygen dependence of antimycin A inhibited oxygen consumption. Mol Biol Rep (2002) 0.90

Flow-cytometric analysis of mitochondria-associated fluorescence in young and old human fibroblasts. Exp Cell Res (1986) 0.90

H2O2-mediated oxidative stress versus cold ischemia-reperfusion: mitochondrial respiratory defects in cultured human endothelial cells. Transplantation (2002) 0.90

Cytochrome c oxidase defects of the human substantia nigra in normal aging. Neurobiol Aging (1997) 0.90

Enhanced expression of cyclin D1 in senescent human fibroblasts. Mech Ageing Dev (1995) 0.88

Increased uptake and retention of rhodamine 123 by mitochondria of old human fibroblasts. Mech Ageing Dev (1987) 0.85

The mitochondrial theory of aging. Biol Signals Recept (2001) 0.85

Aging, longevity, and immortality in vitro. Exp Gerontol (1993) 0.82

Mitochondrial DNA mutations in disease and ageing. Novartis Found Symp (2001) 0.81

Mitochondrial ischemia-reoxygenation injury and plasma membrane integrity in human endothelial cells. Transplant Proc (1997) 0.79

Molecular study of the rat liver NADH: cytochrome c oxidoreductase complex during development and ageing. Mol Cell Biochem (1999) 0.78

Articles by these authors

Deficiency or inhibition of oxygen sensor Phd1 induces hypoxia tolerance by reprogramming basal metabolism. Nat Genet (2008) 3.94

Inhibitory effect of tumor cell-derived lactic acid on human T cells. Blood (2007) 2.64

High-resolution respirometry: OXPHOS protocols for human cells and permeabilized fibers from small biopsies of human muscle. Methods Mol Biol (2012) 2.49

Thiazolidinediones, like metformin, inhibit respiratory complex I: a common mechanism contributing to their antidiabetic actions? Diabetes (2004) 2.39

p16INK4A is a robust in vivo biomarker of cellular aging in human skin. Aging Cell (2006) 2.34

miR-17, miR-19b, miR-20a, and miR-106a are down-regulated in human aging. Aging Cell (2010) 2.31

Cancer cell line identification by short tandem repeat profiling: power and limitations. FASEB J (2005) 1.78

Mitochondrial respiratory chain complex I is inactivated by NADPH oxidase Nox4. Biochem J (2013) 1.74

Explaining the escalation of drug use in substance dependence: models and appropriate animal laboratory tests. Pharmacology (2007) 1.62

Mistargeting of peroxisomal EHHADH and inherited renal Fanconi's syndrome. N Engl J Med (2014) 1.53

Age-related loss of naïve T cells and dysregulation of T-cell/B-cell interactions in human lymph nodes. Immunology (2005) 1.47

Similar qualitative and quantitative changes of mitochondrial respiration following strength and endurance training in normoxia and hypoxia in sedentary humans. Am J Physiol Regul Integr Comp Physiol (2011) 1.38

Metabolic analysis of senescent human fibroblasts reveals a role for AMP in cellular senescence. Biochem J (2003) 1.24

Lactic acid and acidification inhibit TNF secretion and glycolysis of human monocytes. J Immunol (2009) 1.22

The mitochondrial ribosomal protein of the large subunit, Afo1p, determines cellular longevity through mitochondrial back-signaling via TOR1. Aging (Albany NY) (2009) 1.21

Oxidative stress and mitochondrial impairment can be separated from lipofuscin accumulation in aged human skeletal muscle. Aging Cell (2007) 1.21

ROS signaling by NOX4 drives fibroblast-to-myofibroblast differentiation in the diseased prostatic stroma. Mol Endocrinol (2011) 1.21

Mitochondrial defects and heterogeneous cytochrome c release after cardiac cold ischemia and reperfusion. Am J Physiol Heart Circ Physiol (2003) 1.18

Evaluation of mitochondrial respiratory function in small biopsies of liver. Anal Biochem (2002) 1.17

CD25-expressing CD8+ T cells are potent memory cells in old age. J Immunol (2005) 1.16

The SUMO-E3 ligase PIAS3 targets pyruvate kinase M2. J Cell Biochem (2009) 1.15

Glucocorticoid-induced apoptosis and glucocorticoid resistance in acute lymphoblastic leukemia. J Steroid Biochem Mol Biol (2005) 1.13

The role of haemoglobin mass on VO(2)max following normobaric 'live high-train low' in endurance-trained athletes. Br J Sports Med (2012) 1.12

Transcription and enhancer profiling in human monocyte subsets. Blood (2014) 1.12

Senescence-associated cell death of human endothelial cells: the role of oxidative stress. Exp Gerontol (2003) 1.10

Mitochondrial respiratory control and early defects of oxidative phosphorylation in the failing human heart. Int J Biochem Cell Biol (2011) 1.09

Temporal increase of platelet mitochondrial respiration is negatively associated with clinical outcome in patients with sepsis. Crit Care (2010) 1.09

Identification of evolutionarily conserved genetic regulators of cellular aging. Aging Cell (2010) 1.09

Isotype-specific inhibitors of the glycolytic key regulator pyruvate kinase subtype M2 moderately decelerate tumor cell proliferation. Int J Cancer (2008) 1.08

Changes of mitochondrial respiration, mitochondrial content and cell size after induction of apoptosis in leukemia cells. Biochim Biophys Acta (2003) 1.08

Mitochondrial dysfunction--a pharmacological target in Alzheimer's disease. Mol Neurobiol (2012) 1.07

Partial uncoupling of oxidative phosphorylation induces premature senescence in human fibroblasts and yeast mother cells. Free Radic Biol Med (2007) 1.06

Muscle mitochondrial capacity exceeds maximal oxygen delivery in humans. Mitochondrion (2010) 1.06

Age-related differences in phenotype and function of CD4+ T cells are due to a phenotypic shift from naive to memory effector CD4+ T cells. Int Immunol (2005) 1.04

Differential proteomic profiling of mitochondria from Podospora anserina, rat and human reveals distinct patterns of age-related oxidative changes. Exp Gerontol (2007) 1.04

The NADPH oxidase Nox4 restricts the replicative lifespan of human endothelial cells. Biochem J (2009) 1.03

Cell respiration under hypoxia: facts and artefacts in mitochondrial oxygen kinetics. Adv Exp Med Biol (2010) 1.03

Differential regulation of apoptotic cell death in senescent human cells. Exp Gerontol (2004) 1.02

IgG opsonization of HIV impedes provirus formation in and infection of dendritic cells and subsequent long-term transfer to T cells. J Immunol (2007) 1.02

A Darwinian-evolutionary concept of age-related diseases. Exp Gerontol (2003) 1.01

High level HPV-16 E7 oncoprotein expression correlates with reduced pRb-levels in cervical biopsies. FASEB J (2004) 1.01

Disruption of vascular endothelial homeostasis by tobacco smoke: impact on atherosclerosis. FASEB J (2003) 1.00

Development and evaluation of an in vitro model for the analysis of cigarette smoke effects on cultured cells and tissues. J Pharmacol Toxicol Methods (2004) 0.99

Nuclear insulin-like growth factor binding protein-3 induces apoptosis and is targeted to ubiquitin/proteasome-dependent proteolysis. Cancer Res (2006) 0.99

Mitochondrial bioenergetic adaptations of breast cancer cells to aglycemia and hypoxia. J Bioenerg Biomembr (2010) 0.96

Neuroendocrine differentiation of human prostatic primary epithelial cells in vitro. Prostate (2002) 0.95

Apoptosis resistance of senescent human fibroblasts is correlated with the absence of nuclear IGFBP-3. Aging Cell (2005) 0.94

Sustained inhibition of oxidative phosphorylation impairs cell proliferation and induces premature senescence in human fibroblasts. Exp Gerontol (2006) 0.93

Techniques in gerontology: cell lines as standards for telomere length and telomerase activity assessment. Exp Gerontol (2006) 0.93

Replicative senescence of human fibroblasts: the role of Ras-dependent signaling and oxidative stress. Exp Gerontol (2002) 0.91

Functional interplay between mitochondrial and proteasome activity in skin aging. J Invest Dermatol (2010) 0.91

Immunologic and metabolic characteristics of HPV-negative and HPV-positive head and neck squamous cell carcinomas are strikingly different. Virchows Arch (2014) 0.91

Biphasic oxygen kinetics of cellular respiration and linear oxygen dependence of antimycin A inhibited oxygen consumption. Mol Biol Rep (2002) 0.90

Premature senescence of human endothelial cells induced by inhibition of glutaminase. Biogerontology (2008) 0.90

H2O2-mediated oxidative stress versus cold ischemia-reperfusion: mitochondrial respiratory defects in cultured human endothelial cells. Transplantation (2002) 0.90

High-risk human papillomavirus E7 oncoprotein detection in cervical squamous cell carcinoma. Clin Cancer Res (2007) 0.89

Mitochondrial function in human skeletal muscle following high-altitude exposure. Exp Physiol (2012) 0.89

Nucleus accumbens core acetylcholine is preferentially activated during acquisition of drug- vs food-reinforced behavior. Neuropsychopharmacology (2008) 0.88

ATM-dependent phosphorylation of SNEVhPrp19/hPso4 is involved in extending cellular life span and suppression of apoptosis. Aging (Albany NY) (2012) 0.87

Photoaging as a consequence of natural and therapeutic ultraviolet irradiation--studies on PUVA-induced senescence-like growth arrest of human dermal fibroblasts. Exp Gerontol (2003) 0.87

Dimebon ameliorates amyloid-β induced impairments of mitochondrial form and function. J Alzheimers Dis (2012) 0.87

Activation of PKCzeta and PKMzeta in the nucleus accumbens core is necessary for the retrieval, consolidation and reconsolidation of drug memory. PLoS One (2012) 0.87

Two functionally distinct isoforms of TL1A (TNFSF15) generated by differential ectodomain shedding. J Gerontol A Biol Sci Med Sci (2010) 0.87

Decreased affinity for oxygen of cytochrome-c oxidase in Leigh syndrome caused by SURF1 mutations. Am J Physiol Cell Physiol (2004) 0.86

Identification of cultivation-independent markers of human endothelial cell senescence in vitro. Biogerontology (2007) 0.86

Post-translational modification of cellular proteins by ubiquitin and ubiquitin-like molecules: role in cellular senescence and aging. Adv Exp Med Biol (2010) 0.86

Non-regulatory CD8+CD45RO+CD25+ T-lymphocytes may compensate for the loss of antigen-inexperienced CD8+CD45RA+ T-cells in old age. Biol Chem (2008) 0.86

Mitochondrial gene therapy improves respiration, biogenesis, and transcription in G11778A Leber's hereditary optic neuropathy and T8993G Leigh's syndrome cells. Hum Gene Ther (2012) 0.85

Subcellular localization of the human papillomavirus 16 E7 oncoprotein in CaSki cells and its detection in cervical adenocarcinoma and adenocarcinoma in situ. Virology (2010) 0.84

Preserved coupling of oxidative phosphorylation but decreased mitochondrial respiratory capacity in IL-1beta-treated human peritoneal mesothelial cells. Cell Biochem Biophys (2006) 0.83

Mitochondrial ischemia-reperfusion injury of the transplanted rat heart: improved protection by preservation versus cardioplegic solutions. Shock (2008) 0.82

Cholinergic neurons degenerate when exposed to conditioned medium of primary rat brain capillary endothelial cells: counteraction by NGF, MK-801 and inflammation. Exp Gerontol (2006) 0.82

Identification of human fumarylacetoacetate hydrolase domain-containing protein 1 (FAHD1) as a novel mitochondrial acylpyruvase. J Biol Chem (2011) 0.82

Simultaneous high-resolution measurement of mitochondrial respiration and hydrogen peroxide production. Methods Mol Biol (2015) 0.82

Kinetic model of the inhibition of respiration by endogenous nitric oxide in intact cells. Biochim Biophys Acta (2010) 0.82

Physical fitness and mitochondrial respiratory capacity in horse skeletal muscle. PLoS One (2012) 0.81

Insulin-like growth factor-induced signals activate mitochondrial respiration. Biotechnol J (2008) 0.81

Methionine restriction slows down senescence in human diploid fibroblasts. Aging Cell (2014) 0.81

Identification of microRNA-mRNA functional interactions in UVB-induced senescence of human diploid fibroblasts. BMC Genomics (2013) 0.81

Endogenous myoglobin in breast cancer is hypoxia-inducible by alternative transcription and functions to impair mitochondrial activity: a role in tumor suppression? J Biol Chem (2011) 0.81

Role of endonuclease G in senescence-associated cell death of human endothelial cells. Exp Gerontol (2010) 0.80

Progression of arteriovenous bypass restenosis in mice exposed to a 50 Hz magnetic field. Cell Stress Chaperones (2003) 0.80

The human papillomavirus type 16 E7 oncoprotein targets Myc-interacting zinc-finger protein-1. Virology (2011) 0.80

Age-dependent posttranslational modifications of voltage-dependent anion channel 1. Exp Gerontol (2010) 0.80

Heterologous prime-boost immunizations with a virosomal and an alphavirus replicon vaccine. Mol Pharm (2010) 0.79

Human papillomavirus type 16 E7 oncoprotein inhibits apoptosis mediated by nuclear insulin-like growth factor-binding protein-3 by enhancing its ubiquitin/proteasome-dependent degradation. Carcinogenesis (2007) 0.79

Expression of the high-risk human papillomavirus type 18 and 45 E7 oncoproteins in cervical carcinoma biopsies. J Gen Virol (2005) 0.79

New aspects of an old drug--diclofenac targets MYC and glucose metabolism in tumor cells. PLoS One (2013) 0.79

Response of human peritoneal mesothelial cells to inflammatory injury is regulated by interleukin-1beta and tumor necrosis factor-alpha. Wound Repair Regen (2006) 0.79

Human papillomavirus type 45 E7 is a transforming protein inducing retinoblastoma protein degradation and anchorage-independent cell cycle progression. Virology (2008) 0.79

Mitochondrial function in glucocorticoid triggered T-ALL cells with transgenic bcl-2 expression. Mol Biol Rep (2002) 0.79

Clinical significance of inhibition kinetics for Streptococcus pyogenes in response to penicillin. J Antimicrob Chemother (2002) 0.79

Analysis of the cellular uptake and nuclear delivery of insulin-like growth factor binding protein-3 in human osteosarcoma cells. Int J Cancer (2011) 0.78

Cystathionine beta synthase modulates senescence of human endothelial cells. Aging (Albany NY) (2012) 0.78

Monitoring of ubiquitin-proteasome activity in living cells using a Degron (dgn)-destabilized green fluorescent protein (GFP)-based reporter protein. J Vis Exp (2012) 0.78