Neurotransmitter transporters: why dance with so many partners?

PubWeight™: 0.90‹?›

🔗 View Article (PMID 15018836)

Published in Curr Opin Pharmacol on February 01, 2004

Authors

Marco I González1, Michael B Robinson

Author Affiliations

1: Departments of Pediatrics and Pharmacology, Children's Hospital of Philadelphia, University of Pennsylvania, 502 N Abramson Pediatric Research Building, 3615 Civic Center Blvd, Philadelphia, PA 19104-4318, USA.

Articles by these authors

Presynaptic regulation of astroglial excitatory neurotransmitter transporter GLT1. Neuron (2009) 2.48

The role of glutamate transporters in neurodegenerative diseases and potential opportunities for intervention. Neurochem Int (2007) 2.11

A pilot study of in vivo liver-directed gene transfer with an adenoviral vector in partial ornithine transcarbamylase deficiency. Hum Gene Ther (2002) 1.96

Regulation of astrocytic glutamate transporter expression by Akt: evidence for a selective transcriptional effect on the GLT-1/EAAT2 subtype. J Neurochem (2006) 1.35

Behavioral and neurochemical alterations in mice lacking the RNA-binding protein translin. J Neurosci (2006) 1.25

Epigenetic regulation of neuron-dependent induction of astroglial synaptic protein GLT1. Glia (2010) 1.25

Co-compartmentalization of the astroglial glutamate transporter, GLT-1, with glycolytic enzymes and mitochondria. J Neurosci (2011) 1.18

Protein kinase C activation decreases cell surface expression of the GLT-1 subtype of glutamate transporter. Requirement of a carboxyl-terminal domain and partial dependence on serine 486. J Biol Chem (2002) 1.15

Rapid trafficking of the neuronal glutamate transporter, EAAC1: evidence for distinct trafficking pathways differentially regulated by protein kinase C and platelet-derived growth factor. J Biol Chem (2004) 1.14

Real-time monitoring of coronary care mortality: a comparison and combination of two monitoring tools. Int J Cardiol (2005) 1.09

Increased expression of the neuronal glutamate transporter (EAAT3/EAAC1) in hippocampal and neocortical epilepsy. Epilepsia (2002) 1.08

Caveolin-1 regulates the delivery and endocytosis of the glutamate transporter, excitatory amino acid carrier 1. J Biol Chem (2007) 1.03

Identification of motifs involved in endoplasmic reticulum retention-forward trafficking of the GLT-1 subtype of glutamate transporter. J Neurosci (2004) 1.02

Neuronal activity and glutamate uptake decrease mitochondrial mobility in astrocytes and position mitochondria near glutamate transporters. J Neurosci (2014) 0.97

Impaired glutamate transport in a mouse model of tau pathology in astrocytes. J Neurosci (2006) 0.97

Constitutive endocytosis and recycling of the neuronal glutamate transporter, excitatory amino acid carrier 1. J Neurochem (2007) 0.97

The glutamate transporter, GLAST, participates in a macromolecular complex that supports glutamate metabolism. Neurochem Int (2012) 0.97

Internalization and degradation of the glutamate transporter GLT-1 in response to phorbol ester. Neurochem Int (2007) 0.96

Inhibitors of glutamate dehydrogenase block sodium-dependent glutamate uptake in rat brain membranes. Front Endocrinol (Lausanne) (2013) 0.96

Ubiquitination-mediated internalization and degradation of the astroglial glutamate transporter, GLT-1. Neurochem Int (2008) 0.95

Nuclear factor-κB contributes to neuron-dependent induction of glutamate transporter-1 expression in astrocytes. J Neurosci (2011) 0.95

Behavioral changes and dopaminergic dysregulation in mice lacking the nuclear receptor Rev-erbα. Mol Endocrinol (2014) 0.92

The endoplasmic reticulum exit of glutamate transporter is regulated by the inducible mammalian Yip6b/GTRAP3-18 protein. J Biol Chem (2007) 0.92

Evidence that protein kinase Calpha interacts with and regulates the glial glutamate transporter GLT-1. J Neurochem (2005) 0.90

Rottlerin, an inhibitor of protein kinase Cdelta (PKCdelta), inhibits astrocytic glutamate transport activity and reduces GLAST immunoreactivity by a mechanism that appears to be PKCdelta-independent. J Neurochem (2003) 0.90

Protein kinase C-dependent remodeling of glutamate transporter function. Mol Interv (2004) 0.90

Phorbol myristate acetate-dependent interaction of protein kinase Calpha and the neuronal glutamate transporter EAAC1. J Neurosci (2003) 0.88

A carboxyl-terminal determinant of the neuronal glutamate transporter, EAAC1, is required for platelet-derived growth factor-dependent trafficking. J Biol Chem (2005) 0.87

Evidence that Akt mediates platelet-derived growth factor-dependent increases in activity and surface expression of the neuronal glutamate transporter, EAAC1. Neuropharmacology (2005) 0.86

N-methyl-D-aspartate receptor-dependent regulation of the glutamate transporter excitatory amino acid carrier 1. J Biol Chem (2007) 0.86

A dominant-negative variant of SNAP-23 decreases the cell surface expression of the neuronal glutamate transporter EAAC1 by slowing constitutive delivery. Neurochem Int (2006) 0.85

Regulation of the neuronal glutamate transporter excitatory amino acid carrier-1 (EAAC1) by different protein kinase C subtypes. Mol Pharmacol (2002) 0.84

Differential regulation of GLAST immunoreactivity and activity by protein kinase C: evidence for modification of amino and carboxyl termini. J Neurochem (2004) 0.84

Inhibition of glutamate carboxypeptidase II (NAALADase) protects against dynorphin A-induced ischemic spinal cord injury in rats. Eur J Pharmacol (2005) 0.83

mRNA for the EAAC1 subtype of glutamate transporter is present in neuronal dendrites in vitro and dramatically increases in vivo after a seizure. Neurochem Int (2010) 0.81

Group I mGluR-regulated translation of the neuronal glutamate transporter, excitatory amino acid carrier 1. J Neurochem (2011) 0.78

Cerebrospinal fluid glutamine, tryptophan, and tryptophan metabolite concentrations in dogs with portosystemic shunts. Am J Vet Res (2002) 0.77