PubRank

Kornel E Schuebel

Author PubWeight™ 59.33‹?›

Top papers

Rank Title Journal Year PubWeight™‹?›
1 A stem cell-like chromatin pattern may predispose tumor suppressor genes to DNA hypermethylation and heritable silencing. Nat Genet 2007 9.47
2 DNMT1 and DNMT3b cooperate to silence genes in human cancer cells. Nature 2002 9.40
3 Epigenetic inactivation of SFRP genes allows constitutive WNT signaling in colorectal cancer. Nat Genet 2004 7.78
4 Short double-stranded RNA induces transcriptional gene silencing in human cancer cells in the absence of DNA methylation. Nat Genet 2005 3.66
5 Epigenetic inactivation of the canonical Wnt antagonist SRY-box containing gene 17 in colorectal cancer. Cancer Res 2008 2.16
6 Genomic and epigenomic integration identifies a prognostic signature in colon cancer. Clin Cancer Res 2011 2.06
7 Methylation of TFPI2 in stool DNA: a potential novel biomarker for the detection of colorectal cancer. Cancer Res 2009 1.80
8 De novo CpG island methylation in human cancer cells. Cancer Res 2006 1.73
9 Convergence of mutation and epigenetic alterations identifies common genes in cancer that predict for poor prognosis. PLoS Med 2008 1.70
10 Defining a chromatin pattern that characterizes DNA-hypermethylated genes in colon cancer cells. Cancer Res 2008 1.69
11 Epigenetic inactivation of CHFR in human tumors. Proc Natl Acad Sci U S A 2003 1.57
12 Abnormal DNA methylation of CD133 in colorectal and glioblastoma tumors. Cancer Res 2008 1.51
13 Regulation of neuroendocrine differentiation in gastrointestinal carcinoid tumor cells by notch signaling. J Clin Endocrinol Metab 2005 1.39
14 Concomitant promoter methylation of multiple genes in lung adenocarcinomas from current, former and never smokers. Carcinogenesis 2009 1.25
15 Cancer-related epigenome changes associated with reprogramming to induced pluripotent stem cells. Cancer Res 2010 1.24
16 CpG island hypermethylation is maintained in human colorectal cancer cells after RNAi-mediated depletion of DNMT1. Nat Genet 2004 1.22
17 Epigenetic regulation of WNT signaling pathway genes in inflammatory bowel disease (IBD) associated neoplasia. J Gastrointest Surg 2008 1.12
18 Aberrant silencing of cancer-related genes by CpG hypermethylation occurs independently of their spatial organization in the nucleus. Cancer Res 2010 1.10
19 Differential requirement for DNA methyltransferase 1 in maintaining human cancer cell gene promoter hypermethylation. Cancer Res 2006 1.09
20 A requirement for DICER to maintain full promoter CpG island hypermethylation in human cancer cells. Cancer Res 2008 1.08
21 Biomarkers for detection and prognosis of breast cancer identified by a functional hypermethylome screen. Epigenetics 2012 1.07
22 Prognostic significance of Gremlin1 (GREM1) promoter CpG island hypermethylation in clear cell renal cell carcinoma. Am J Pathol 2009 1.00
23 Frequent inactivation of cysteine dioxygenase type 1 contributes to survival of breast cancer cells and resistance to anthracyclines. Clin Cancer Res 2013 0.94
24 Mammalian DNA methyltransferase 1: inspiration for new directions. Cell Cycle 2004 0.88
25 Genomic biology: the epigenomic era opens. Nature 2007 0.86
26 Functional identification of cancer-specific methylation of CDO1, HOXA9, and TAC1 for the diagnosis of lung cancer. Clin Cancer Res 2014 0.83
27 Epigenetic silencing of neurofilament genes promotes an aggressive phenotype in breast cancer. Epigenetics 2015 0.78