A stem cell-like chromatin pattern may predispose tumor suppressor genes to DNA hypermethylation and heritable silencing.

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Published in Nat Genet on January 09, 2007


Joyce E Ohm1, Kelly M McGarvey, Xiaobing Yu, Linzhao Cheng, Kornel E Schuebel, Leslie Cope, Helai P Mohammad, Wei Chen, Vincent C Daniel, Wayne Yu, David M Berman, Thomas Jenuwein, Kevin Pruitt, Saul J Sharkis, D Neil Watkins, James G Herman, Stephen B Baylin

Author Affiliations

1: Cancer Biology Division, The Sidney Kimmel Comprehensive Cancer Center.

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