Published in Proc Natl Acad Sci U S A on March 24, 2004
ROS and p53: a versatile partnership. Free Radic Biol Med (2008) 2.52
Augmented BMP signaling in the neural crest inhibits nasal cartilage morphogenesis by inducing p53-mediated apoptosis. Development (2015) 0.93
Interaction of an anticancer peptide fragment of azurin with p53 and its isolated domains studied by atomic force spectroscopy. Int J Nanomedicine (2011) 0.87
Modulation of membrane properties of lung cancer cells by azurin enhances the sensitivity to EGFR-targeted therapy and decreased β1 integrin-mediated adhesion. Cell Cycle (2016) 0.87
Potent and tumor specific: arming bacteria with therapeutic proteins. Ther Deliv (2015) 0.86
Microbial-based therapy of cancer: current progress and future prospects. Bioeng Bugs (2009) 0.83
Bacterial proteins and peptides in cancer therapy: today and tomorrow. Bioengineered (2014) 0.82
Escherichia coli Nissle 1917 targets and restrains mouse B16 melanoma and 4T1 breast tumors through expression of azurin protein. Appl Environ Microbiol (2012) 0.82
SERS-based nanobiosensing for ultrasensitive detection of the p53 tumor suppressor. Int J Nanomedicine (2011) 0.79
The bacterial protein azurin impairs invasion and FAK/Src signaling in P-cadherin-overexpressing breast cancer cell models. PLoS One (2013) 0.79
Molecular dynamic simulation insights into the normal state and restoration of p53 function. Int J Mol Sci (2012) 0.78
Building Cell Selectivity into CPP-Mediated Strategies. Pharmaceuticals (Basel) (2010) 0.78
Discovery of Azurin-Like Anticancer Bacteriocins from Human Gut Microbiome through Homology Modeling and Molecular Docking against the Tumor Suppressor p53. Biomed Res Int (2016) 0.78
Structural studies on Laz, a promiscuous anticancer Neisserial protein. Bioengineered (2015) 0.75
Bacterial azurin in potential cancer therapy. Cell Cycle (2016) 0.75
Re-engineered p53 activates apoptosis in vivo and causes primary tumor regression in a dominant negative breast cancer xenograft model. Gene Ther (2014) 0.75
Analysis of relative gene expression data using real-time quantitative PCR and the 2(-Delta Delta C(T)) Method. Methods (2001) 414.27
Surfing the p53 network. Nature (2000) 35.36
CDK inhibitors: positive and negative regulators of G1-phase progression. Genes Dev (1999) 24.83
The p53 pathway. J Pathol (1999) 6.79
Decision making by p53: life, death and cancer. Cell Death Differ (2003) 5.52
The Pezcoller lecture: cancer cell cycles revisited. Cancer Res (2000) 5.08
Analysis of p53-regulated gene expression patterns using oligonucleotide arrays. Genes Dev (2000) 5.04
Phagocytosis and cytolysis by a macrophage tumour and its cloned cell line. Nature (1975) 3.43
Mechanisms of p53-dependent apoptosis. Biochem Soc Trans (2001) 2.96
p21(WAF1/Cip1): more than a break to the cell cycle? Biochim Biophys Acta (2000) 2.81
Regulation of p53 stability and p53-dependent apoptosis by NADH quinone oxidoreductase 1. Proc Natl Acad Sci U S A (2001) 2.10
Hepatitis C virus NS5A physically associates with p53 and regulates p21/waf1 gene expression in a p53-dependent manner. J Virol (2001) 1.73
Bacterial redox protein azurin, tumor suppressor protein p53, and regression of cancer. Proc Natl Acad Sci U S A (2002) 1.41
The C-terminus of p53: the more you learn the less you know. Nat Struct Biol (2001) 1.34
Cyclin E, a redundant cyclin in breast cancer. Proc Natl Acad Sci U S A (1996) 1.32
BRCA1 directs a selective p53-dependent transcriptional response towards growth arrest and DNA repair targets. Mol Cell Biol (2002) 1.28
Blue copper proteins: a comparative analysis of their molecular interaction properties. Protein Sci (2000) 1.12
The bacterial redox protein azurin induces apoptosis in J774 macrophages through complex formation and stabilization of the tumor suppressor protein p53. Infect Immun (2002) 1.08
Expression of the cyclin-dependent kinase inhibitors p16INK4, p15INK4B and p21WAF1/CIP1 in human breast cancer. Int J Cancer (1995) 1.04
Electron donation between copper containing nitrite reductases and cupredoxins: the nature of protein-protein interaction in complex formation. J Mol Biol (2002) 0.93
Induction of apoptosis in macrophages by Pseudomonas aeruginosa azurin: tumour-suppressor protein p53 and reactive oxygen species, but not redox activity, as critical elements in cytotoxicity. Mol Microbiol (2003) 0.92
Pseudomonas aeruginosa cytochrome C(551): probing the role of the hydrophobic patch in electron transfer. J Inorg Biochem (2002) 0.91
Bacterial cupredoxin azurin and its interactions with the tumor suppressor protein p53. Biochem Biophys Res Commun (2003) 0.89
Increased gene expression and production of murine endothelin receptors after birth. Biochem Biophys Res Commun (2003) 0.88
Retinoblastoma function is a better indicator of cellular phenotype in cultured breast adenocarcinoma cells than retinoblastoma expression. Exp Biol Med (Maywood) (2002) 0.82
Expression of CDK inhibitor genes in immortalized and carcinoma derived breast cell lines. Anticancer Res (1996) 0.80
Ionizing radiation and teniposide increase p21(waf1/cip1) and promote Rb dephosphorylation but fail to suppress E2F activity in MCF-7 breast tumor cells. Mol Pharmacol (1997) 0.78
Randomized trial of an allogeneic melanoma lysate vaccine with low-dose interferon Alfa-2b compared with high-dose interferon Alfa-2b for Resected stage III cutaneous melanoma. J Clin Oncol (2007) 2.19
Nardilysin prevents amyloid plaque formation by enhancing α-secretase activity in an Alzheimer's disease mouse model. Neurobiol Aging (2013) 1.46
Bacterial redox protein azurin, tumor suppressor protein p53, and regression of cancer. Proc Natl Acad Sci U S A (2002) 1.41
Specific recognition of apoptotic cells reveals a ubiquitous and unconventional innate immunity. J Biol Chem (2006) 1.25
Bacterial cupredoxin azurin as an inducer of apoptosis and regression in human breast cancer. Oncogene (2004) 1.22
Cupredoxin-cancer interrelationship: azurin binding with EphB2, interference in EphB2 tyrosine phosphorylation, and inhibition of cancer growth. Biochemistry (2007) 1.22
High-throughput identification and screening of novel Methylobacterium species using whole-cell MALDI-TOF/MS analysis. PLoS One (2012) 1.16
Structure and conservation of a polyethylene glycol-degradative operon in sphingomonads. Microbiology (2007) 1.15
Noncationic peptides obtained from azurin preferentially enter cancer cells. Cancer Res (2009) 1.15
Diversity of 2,3-dihydroxybiphenyl dioxygenase genes in a strong PCB degrader, Rhodococcus sp. strain RHA1. J Biosci Bioeng (2002) 1.11
Novel approach to the improvement of biphenyl and polychlorinated biphenyl degradation activity: promoter implantation by homologous recombination. Appl Environ Microbiol (2003) 1.11
Internalization of bacterial redox protein azurin in mammalian cells: entry domain and specificity. Cell Microbiol (2005) 1.10
Nardilysin regulates axonal maturation and myelination in the central and peripheral nervous system. Nat Neurosci (2009) 1.08
The bacterial redox protein azurin induces apoptosis in J774 macrophages through complex formation and stabilization of the tumor suppressor protein p53. Infect Immun (2002) 1.08
Nardilysin enhances ectodomain shedding of heparin-binding epidermal growth factor-like growth factor through activation of tumor necrosis factor-alpha-converting enzyme. J Biol Chem (2006) 1.07
Role of microphthalmia transcription factor (Mitf) in melanoma differentiation. Biochem Biophys Res Commun (2007) 1.04
A cell penetrating peptide derived from azurin inhibits angiogenesis and tumor growth by inhibiting phosphorylation of VEGFR-2, FAK and Akt. Angiogenesis (2011) 1.00
Azurin, Plasmodium falciparum malaria and HIV/AIDS: inhibition of parasitic and viral growth by Azurin. Cell Cycle (2006) 0.99
Bacterial proteins and CpG-rich extrachromosomal DNA in potential cancer therapy. Plasmid (2006) 0.98
A novel RARbeta isoform directed by a distinct promoter P3 and mediated by retinoic acid in breast cancer cells. Cancer Res (2004) 0.97
Beyond host-pathogen interactions: microbial defense strategy in the host environment. Curr Opin Biotechnol (2007) 0.95
Practical application of methanol-mediated mutualistic symbiosis between Methylobacterium species and a roof greening moss, Racomitrium japonicum. PLoS One (2012) 0.95
Flow cytometry analysis of changes in the DNA content of the polychlorinated biphenyl degrader Comamonas testosteroni TK102: effect of metabolites on cell-cell separation. Appl Environ Microbiol (2002) 0.95
Isolation of bacteria able to grow on both polyethylene glycol (PEG) and polypropylene glycol (PPG) and their PEG/PPG dehydrogenases. Appl Microbiol Biotechnol (2006) 0.94
A peptide fragment of azurin induces a p53-mediated cell cycle arrest in human breast cancer cells. Mol Cancer Ther (2009) 0.94
Leishmania-released nucleoside diphosphate kinase prevents ATP-mediated cytolysis of macrophages. Mol Biochem Parasitol (2007) 0.93
Azurin-like protein blocks invasion of Toxoplasma gondii through potential interactions with parasite surface antigen SAG1. Antimicrob Agents Chemother (2007) 0.93
Single-cell analyses revealed transfer ranges of IncP-1, IncP-7, and IncP-9 plasmids in a soil bacterial community. Appl Environ Microbiol (2013) 0.92
Induction of apoptosis in macrophages by Pseudomonas aeruginosa azurin: tumour-suppressor protein p53 and reactive oxygen species, but not redox activity, as critical elements in cytotoxicity. Mol Microbiol (2003) 0.92
Disrupting the entry barrier and attacking brain tumors: the role of the Neisseria H.8 epitope and the Laz protein. Cell Cycle (2006) 0.92
The crucial role of mitochondrial regulation in adaptive aluminium resistance in Rhodotorula glutinis. Microbiology (2008) 0.90
Analysis of amino acid residues involved in catalysis of polyethylene glycol dehydrogenase from Sphingopyxis terrae, using three-dimensional molecular modeling-based kinetic characterization of mutants. Appl Environ Microbiol (2006) 0.90
Melanoma cells can tolerate high levels of transcriptionally active endogenous p53 but are sensitive to retrovirus-transduced p53. Oncogene (2003) 0.90
bph genes of the thermophilic PCB degrader, Bacillus sp. JF8: characterization of the divergent ring-hydroxylating dioxygenase and hydrolase genes upstream of the Mn-dependent BphC. Microbiology (2005) 0.89
Bacterial cupredoxin azurin and its interactions with the tumor suppressor protein p53. Biochem Biophys Res Commun (2003) 0.89
Culturable bacteria in hydroponic cultures of moss Racomitrium japonicum and their potential as biofertilizers for moss production. J Biosci Bioeng (2011) 0.89
A threshold exists in the dose-response relationship for somatic mutation frequency induced by X irradiation of Drosophila. Radiat Res (2004) 0.89
Nardilysin and ADAM proteases promote gastric cancer cell growth by activating intrinsic cytokine signalling via enhanced ectodomain shedding of TNF-α. EMBO Mol Med (2012) 0.88
Engineering of bacterial strains and their products for cancer therapy. Appl Microbiol Biotechnol (2013) 0.87
A bacterial biosensor for oxidative stress using the constitutively expressed redox-sensitive protein roGFP2. Sensors (Basel) (2010) 0.87
MADD knock-down enhances doxorubicin and TRAIL induced apoptosis in breast cancer cells. PLoS One (2013) 0.86
Preclinical pharmacokinetics, metabolism, and toxicity of azurin-p28 (NSC745104) a peptide inhibitor of p53 ubiquitination. Cancer Chemother Pharmacol (2010) 0.86
Overcoming drug resistance in multi-drug resistant cancers and microorganisms: a conceptual framework. Bioengineered (2012) 0.86
Biochemical and molecular characterization of a periplasmic hydrolase for oxidized polyvinyl alcohol from Sphingomonas sp. strain 113P3. Microbiology (2005) 0.85
Genes for Mn(II)-dependent NahC and Fe(II)-dependent NahH located in close proximity in the thermophilic naphthalene and PCB degrader, Bacillus sp. JF8: cloning and characterization. Microbiology (2004) 0.85
Bacterial proteins as potential drugs in the treatment of leukemia. Leuk Res (2009) 0.85
The pva operon is located on the megaplasmid of Sphingopyxis sp. strain 113P3 and is constitutively expressed, although expression is enhanced by PVA. Appl Microbiol Biotechnol (2008) 0.84
Cloning and expression of the gene for periplasmic poly(vinyl alcohol) dehydrogenase from Sphingomonas sp. strain 113P3, a novel-type quinohaemoprotein alcohol dehydrogenase. Microbiology (2006) 0.84
Proposed oxidative metabolic pathway for polypropylene glycol in Sphingobium sp. strain PW-1. Biosci Biotechnol Biochem (2008) 0.84
Predicting residual lymph node basin disease in melanoma patients with sentinel lymph node metastases. Am J Surg (2003) 0.84
Chemoprevention of mammary carcinogenesis by 1alpha-hydroxyvitamin D5, a synthetic analog of Vitamin D. Mutat Res (2003) 0.83
Extensive reduction of cell viability and enhanced matrix production in Pseudomonas aeruginosa PAO1 flow biofilms treated with a D-amino acid mixture. Appl Environ Microbiol (2012) 0.83
Characterization of a novel thermostable Mn(II)-dependent 2,3-dihydroxybiphenyl 1,2-dioxygenase from a polychlorinated biphenyl- and naphthalene-degrading Bacillus sp. JF8. J Biol Chem (2003) 0.83
Microbial-based therapy of cancer: current progress and future prospects. Bioeng Bugs (2009) 0.83
Intermediate frequency magnetic fields do not have mutagenic, co-mutagenic or gene conversion potentials in microbial genotoxicity tests. Mutat Res (2007) 0.82
Dual regulation of a polyethylene glycol degradative operon by AraC-type and GalR-type regulators in Sphingopyxis macrogoltabida strain 103. Microbiology (2006) 0.82
Methylobacterium gnaphalii sp. nov., isolated from leaves of Gnaphalium spicatum. Int J Syst Evol Microbiol (2011) 0.82
Glioblastoma multiforme: novel therapeutic approaches. ISRN Neurol (2012) 0.82
Metabolic pathway of xenoestrogenic short ethoxy chain-nonylphenol to nonylphenol by aerobic bacteria, Ensifer sp. strain AS08 and Pseudomonas sp. strain AS90. Appl Microbiol Biotechnol (2006) 0.82
Pandoraea oxalativorans sp. nov., Pandoraea faecigallinarum sp. nov. and Pandoraea vervacti sp. nov., isolated from oxalate-enriched culture. Int J Syst Evol Microbiol (2010) 0.81
Modulation of mammalian cell growth and death by prokaryotic and eukaryotic cytochrome c. Proc Natl Acad Sci U S A (2004) 0.81
A 28-amino-acid peptide fragment of the cupredoxin azurin prevents carcinogen-induced mouse mammary lesions. Cancer Prev Res (Phila) (2010) 0.81
Efficacy and mechanism of action of 1alpha-hydroxy-24-ethyl-cholecalciferol (1alpha[OH]D5) in breast cancer prevention and therapy. Recent Results Cancer Res (2003) 0.81
Xenoestrogenic short ethoxy chain nonylphenol is oxidized by a flavoprotein alcohol dehydrogenase from Ensifer sp. strain AS08. Appl Microbiol Biotechnol (2006) 0.80
Complete Genome Sequence of the Thermophilic Polychlorinated Biphenyl Degrader Geobacillus sp. Strain JF8 (NBRC 109937). Genome Announc (2014) 0.80
Regulation of mammalian cell growth and death by bacterial redox proteins: relevance to ecology and cancer therapy. Cell Cycle (2004) 0.80
Law-medicine interfacing: patenting of human genes and mutations. Recent Pat DNA Gene Seq (2011) 0.79
Rapid assessment of the physiological status of the polychlorinated biphenyl degrader Comamonas testosteroni TK102 by flow cytometry. Appl Environ Microbiol (2002) 0.79
Human cytochrome c enters murine J774 cells and causes G1 and G2/M cell cycle arrest and induction of apoptosis. Biochem Biophys Res Commun (2005) 0.79
p28, an anionic cell-penetrating peptide, increases the activity of wild type and mutated p53 without altering its conformation. Mol Pharm (2013) 0.79
Methylobacterium oxalidis sp. nov., isolated from leaves of Oxalis corniculata. Int J Syst Evol Microbiol (2011) 0.79
Indium chloride-induced micronuclei in in vivo and in vitro experimental systems. J Occup Health (2011) 0.79
Strong static magnetic field effects on yeast proliferation and distribution. Bioelectrochemistry (2004) 0.78
Recent patents on live bacteria and their products as potential anticancer agents. Recent Pat Anticancer Drug Discov (2012) 0.78
Genotoxic effects of strong static magnetic fields in DNA-repair defective mutants of Drosophila melanogaster. J Radiat Res (2004) 0.78
Method for assessment of viability and morphological changes of bacteria in the early stage of colony formation on a simulated natural environment. Appl Environ Microbiol (2006) 0.78
Assessment of change in biofilm architecture by nutrient concentration using a multichannel microdevice flow system. J Biosci Bioeng (2012) 0.77
Effect of static magnetic field on the induction of micronuclei by some mutagens. Environ Health Prev Med (2006) 0.77
Genes involved in novel adaptive aluminum resistance in Rhodotorula glutinis. J Biosci Bioeng (2010) 0.77
Polyethylene glycol (PEG)-carboxylate-CoA synthetase is involved in PEG metabolism in Sphingopyxis macrogoltabida strain 103. Arch Microbiol (2007) 0.77
Rusticyanin, a bacterial electron transfer protein, causes G1 arrest in J774 and apoptosis in human cancer cells. Cell Cycle (2004) 0.77
Patent controversies and court cases: cancer diagnosis, therapy and prevention. Cancer Biol Ther (2012) 0.76
Genome Sequence of the 2,4,5-Trichlorophenoxyacetate-Degrading Bacterium Burkholderia phenoliruptrix Strain AC1100. Genome Announc (2013) 0.76