Published in Am J Psychiatry on April 01, 2004
Dysconnection in schizophrenia: from abnormal synaptic plasticity to failures of self-monitoring. Schizophr Bull (2009) 3.82
Neuromodulation of thought: flexibilities and vulnerabilities in prefrontal cortical network synapses. Neuron (2012) 1.99
The computational anatomy of psychosis. Front Psychiatry (2013) 1.84
GABAergic dysfunction in schizophrenia: new treatment strategies on the horizon. Psychopharmacology (Berl) (2005) 1.82
Prenatal and neonatal brain structure and white matter maturation in children at high risk for schizophrenia. Am J Psychiatry (2010) 1.79
Disturbed structural connectivity in schizophrenia primary factor in pathology or epiphenomenon? Schizophr Bull (2007) 1.59
Reelin and glutamic acid decarboxylase67 promoter remodeling in an epigenetic methionine-induced mouse model of schizophrenia. Proc Natl Acad Sci U S A (2005) 1.56
Loss of Microtubule-Associated Protein 2 Immunoreactivity Linked to Dendritic Spine Loss in Schizophrenia. Biol Psychiatry (2015) 1.52
Antipsychotic drugs: comparison in animal models of efficacy, neurotransmitter regulation, and neuroprotection. Pharmacol Rev (2008) 1.46
Review of pathological hallmarks of schizophrenia: comparison of genetic models with patients and nongenetic models. Schizophr Bull (2009) 1.44
Nitric oxide synthase 1 adaptor protein, a protein implicated in schizophrenia, controls radial migration of cortical neurons. Biol Psychiatry (2014) 1.40
Modeling cognitive endophenotypes of schizophrenia in mice. Trends Neurosci (2009) 1.32
NMDA receptor blockade alters stress-induced dendritic remodeling in medial prefrontal cortex. Cereb Cortex (2011) 1.19
Gamma oscillation deficits and the onset and early progression of schizophrenia. Harv Rev Psychiatry (2010) 1.17
Modeling psychiatric disorders at the cellular and network levels. Mol Psychiatry (2012) 1.14
Development of rostral prefrontal cortex and cognitive and behavioural disorders. Dev Med Child Neurol (2008) 1.13
Dopamine depletion of the prefrontal cortex induces dendritic spine loss: reversal by atypical antipsychotic drug treatment. Neuropsychopharmacology (2007) 1.09
Brain plasticity and behaviour in the developing brain. J Can Acad Child Adolesc Psychiatry (2011) 1.08
The functional consequences of cortical circuit abnormalities on gamma oscillations in schizophrenia: insights from computational modeling. Front Hum Neurosci (2009) 1.07
Stress weakens prefrontal networks: molecular insults to higher cognition. Nat Neurosci (2015) 1.06
Modeling heterogeneous patients with a clinical diagnosis of schizophrenia with induced pluripotent stem cells. Biol Psychiatry (2013) 1.05
NOS1AP regulates dendrite patterning of hippocampal neurons through a carboxypeptidase E-mediated pathway. J Neurosci (2009) 1.04
Concise review: the promise of human induced pluripotent stem cell-based studies of schizophrenia. Stem Cells (2011) 1.04
Kalirin loss results in cortical morphological alterations. Mol Cell Neurosci (2009) 1.01
Distinctive transcriptome alterations of prefrontal pyramidal neurons in schizophrenia and schizoaffective disorder. Mol Psychiatry (2015) 0.99
Mean diffusivity: a biomarker for CSF-related disease and genetic liability effects in schizophrenia. Psychiatry Res (2008) 0.98
Altered glutamate protein co-expression network topology linked to spine loss in the auditory cortex of schizophrenia. Biol Psychiatry (2014) 0.95
NOS1AP in schizophrenia. Curr Psychiatry Rep (2008) 0.94
Developmental origins of brain disorders: roles for dopamine. Front Cell Neurosci (2013) 0.94
The glutamate hypothesis of schizophrenia: evidence from human brain tissue studies. Ann N Y Acad Sci (2014) 0.92
Increased expression of Kalirin-9 in the auditory cortex of schizophrenia subjects: its role in dendritic pathology. Neurobiol Dis (2011) 0.92
Effects of davunetide on N-acetylaspartate and choline in dorsolateral prefrontal cortex in patients with schizophrenia. Neuropsychopharmacology (2013) 0.92
Synapse-specific contributions in the cortical pathology of schizophrenia. Neurobiol Dis (2013) 0.91
Dystrophic dendrites in prefrontal cortical pyramidal cells of dopamine D1 and D2 but not D4 receptor knockout mice. Brain Res (2009) 0.90
The neurobiology of thought: the groundbreaking discoveries of Patricia Goldman-Rakic 1937-2003. Cereb Cortex (2013) 0.89
Anatomy and physiology of the thick-tufted layer 5 pyramidal neuron. Front Cell Neurosci (2015) 0.89
Elevated GRIA1 mRNA expression in Layer II/III and V pyramidal cells of the DLPFC in schizophrenia. Schizophr Res (2007) 0.89
Gene expression analysis implicates a death receptor pathway in schizophrenia pathology. PLoS One (2012) 0.88
Differentiating patterns of amygdala-frontal functional connectivity in schizophrenia and bipolar disorder. Schizophr Bull (2013) 0.88
Periadolescent maturation of the prefrontal cortex is sex-specific and is disrupted by prenatal stress. J Comp Neurol (2013) 0.87
DISC1 as a therapeutic target for mental illnesses. Expert Opin Ther Targets (2012) 0.87
Phencyclidine-induced loss of asymmetric spine synapses in rodent prefrontal cortex is reversed by acute and chronic treatment with olanzapine. Neuropsychopharmacology (2011) 0.86
Rapid Ngn2-induction of excitatory neurons from hiPSC-derived neural progenitor cells. Methods (2015) 0.85
Stress during a critical postnatal period induces region-specific structural abnormalities and dysfunction of the prefrontal cortex via CRF1. Neuropsychopharmacology (2015) 0.84
Dendritic spine alterations in schizophrenia. Neurosci Lett (2014) 0.84
Cortical thickness and surface area in neonates at high risk for schizophrenia. Brain Struct Funct (2014) 0.84
Full UPF3B function is critical for neuronal differentiation of neural stem cells. Mol Brain (2015) 0.84
Regional differences in expression of β-tubulin isoforms in schizophrenia. Schizophr Res (2012) 0.83
AMPA glutamate receptor subunits 1 and 2 regulate dendrite complexity and spine motility in neurons of the developing neocortex. Neuroscience (2008) 0.83
Factors influencing cerebral plasticity in the normal and injured brain. Front Hum Neurosci (2010) 0.82
Identifying novel interventional strategies for psychiatric disorders: integrating genomics, 'enviromics' and gene-environment interactions in valid preclinical models. Br J Pharmacol (2014) 0.82
Deciphering the role of docosahexaenoic acid in brain maturation and pathology with magnetic resonance imaging. Prostaglandins Leukot Essent Fatty Acids (2012) 0.81
Isolation rearing or methamphetamine traumatisation induce a "dysconnection" of prefrontal efferents in gerbils: implications for schizophrenia. J Neural Transm (Vienna) (2005) 0.81
Persistent effects of chronic clozapine on the cellular and behavioral responses to LSD in mice. Psychopharmacology (Berl) (2012) 0.81
Imaging brain plasticity after trauma. Neural Regen Res (2014) 0.81
Chronic Stimulation of Alpha-2A-Adrenoceptors With Guanfacine Protects Rodent Prefrontal Cortex Dendritic Spines and Cognition From the Effects of Chronic Stress. Neurobiol Stress (2015) 0.80
Oxytocin and dendrite remodeling in the hypothalamus. Horm Behav (2012) 0.80
Consequences at adulthood of transient inactivation of the parahippocampal and prefrontal regions during early development: new insights from a disconnection animal model for schizophrenia. Front Behav Neurosci (2014) 0.79
Targeting Prefrontal Cortical Systems for Drug Development: Potential Therapies for Cognitive Disorders. Annu Rev Pharmacol Toxicol (2016) 0.79
Ablation of ErbB4 from excitatory neurons leads to reduced dendritic spine density in mouse prefrontal cortex. J Comp Neurol (2014) 0.79
Weaving a Net of Neurobiological Mechanisms in Schizophrenia and Unraveling the Underlying Pathophysiology. Biol Psychiatry (2016) 0.78
Distinct behavioral consequences of short-term and prolonged GABAergic depletion in prefrontal cortex and dorsal hippocampus. Front Behav Neurosci (2015) 0.78
Control of Dendritic Spine Morphological and Functional Plasticity by Small GTPases. Neural Plast (2016) 0.78
Associating schizophrenia, long non-coding RNAs and neurostructural dynamics. Front Mol Neurosci (2015) 0.77
Olanzapine Prevents the PCP-induced Reduction in the Neurite Outgrowth of Prefrontal Cortical Neurons via NRG1. Sci Rep (2016) 0.77
Converging models of schizophrenia - Network alterations of prefrontal cortex underlying cognitive impairments. Prog Neurobiol (2015) 0.76
Schizophrenia: a pathogenetic autoimmune disease caused by viruses and pathogens and dependent on genes. J Pathog (2011) 0.76
A meta-analysis of peripheral blood nerve growth factor levels in patients with schizophrenia. Mol Psychiatry (2017) 0.76
Developing therapeutics for schizophrenia and other psychotic disorders. NeuroRx (2005) 0.75
Multifactorial Modeling of Impairment of Evoked Gamma Range Oscillations in Schizophrenia. Front Comput Neurosci (2016) 0.75
Protein Interaction Networks Link Schizophrenia Risk Loci to Synaptic Function. Schizophr Bull (2016) 0.75
fMRI assessment of thalamocortical connectivity during attentional performance. Magn Reson Imaging (2013) 0.75
The NMDA receptor GluN2C subunit controls cortical excitatory-inhibitory balance, neuronal oscillations and cognitive function. Sci Rep (2016) 0.75
Antipsychotic-induced Hdac2 transcription via NF-κB leads to synaptic and cognitive side effects. Nat Neurosci (2017) 0.75
The modulation of adult neuroplasticity is involved in the mood-improving actions of atypical antipsychotics in an animal model of depression. Transl Psychiatry (2017) 0.75
Transcriptome Alterations in Prefrontal Pyramidal Cells Distinguish Schizophrenia From Bipolar and Major Depressive Disorders. Biol Psychiatry (2017) 0.75
Multiple roles of Ulk4 in neurogenesis and brain function. Neurogenesis (Austin) (2017) 0.75
Basal tree complexity shapes functional pathways in the prefrontal cortex. J Neurophysiol (2017) 0.75
RNA cargoes associating with FMRP reveal deficits in cellular functioning in Fmr1 null mice. Neuron (2003) 3.58
From mRNP trafficking to spine dysmorphogenesis: the roots of fragile X syndrome. Nat Rev Neurosci (2005) 3.46
Mission creep in the IRB world. Science (2006) 2.64
The use of total protein stains as loading controls: an alternative to high-abundance single-protein controls in semi-quantitative immunoblotting. J Neurosci Methods (2008) 2.54
Exercise, experience and the aging brain. Neurobiol Aging (2002) 2.44
Experience-driven brain plasticity: beyond the synapse. Neuron Glia Biol (2004) 2.27
Local protein synthesis and spine morphogenesis: Fragile X syndrome and beyond. J Neurosci (2006) 2.04
Transport of Drosophila fragile X mental retardation protein-containing ribonucleoprotein granules by kinesin-1 and cytoplasmic dynein. Proc Natl Acad Sci U S A (2004) 1.99
Environmental influences on cognitive and brain plasticity during aging. J Gerontol A Biol Sci Med Sci (2004) 1.99
Fragile X mental retardation protein is necessary for neurotransmitter-activated protein translation at synapses. Proc Natl Acad Sci U S A (2004) 1.97
Open-label treatment trial of lithium to target the underlying defect in fragile X syndrome. J Dev Behav Pediatr (2008) 1.91
Sequence of abnormal dendritic spine development in primary somatosensory cortex of a mouse model of the fragile X mental retardation syndrome. Am J Med Genet A (2005) 1.90
Achieving and maintaining cognitive vitality with aging. Mayo Clin Proc (2002) 1.81
Dendritic spine and dendritic field characteristics of layer V pyramidal neurons in the visual cortex of fragile-X knockout mice. Am J Med Genet (2002) 1.76
Application of the ABCD2 score to identify cerebrovascular causes of dizziness in the emergency department. Stroke (2012) 1.65
Motor impairment in rats exposed to PCBs and methylmercury during early development. Toxicol Sci (2003) 1.59
Dendritic spine abnormalities in the occipital cortex of C57BL/6 Fmr1 knockout mice. Am J Med Genet B Neuropsychiatr Genet (2005) 1.55
Dendritic spine instability and insensitivity to modulation by sensory experience in a mouse model of fragile X syndrome. Proc Natl Acad Sci U S A (2010) 1.45
Hippocampal pyramidal cells in adult Fmr1 knockout mice exhibit an immature-appearing profile of dendritic spines. Brain Res (2006) 1.41
Pearls & oy-sters: the use of CT venography in Hirayama disease. Neurology (2012) 1.40
Profiling signaling peptides in single mammalian cells using mass spectrometry. Anal Chem (2006) 1.38
Altered expression of BDNF and its high-affinity receptor TrkB in response to complex motor learning and moderate exercise. Brain Res (2004) 1.33
Spatial profiling with MALDI MS: distribution of neuropeptides within single neurons. Anal Chem (2003) 1.26
Somatosensory cortical barrel dendritic abnormalities in a mouse model of the fragile X mental retardation syndrome. Brain Res (2003) 1.26
A receptor for activated C kinase is part of messenger ribonucleoprotein complexes associated with polyA-mRNAs in neurons. J Neurosci (2002) 1.25
Persistent impairment of hippocampal neurogenesis in young adult rats following early postnatal alcohol exposure. Alcohol Clin Exp Res (2007) 1.25
Altered mRNA transport, docking, and protein translation in neurons lacking fragile X mental retardation protein. Proc Natl Acad Sci U S A (2010) 1.25
Maturation time of new granule cells in the dentate gyrus of adult macaque monkeys exceeds six months. Proc Natl Acad Sci U S A (2011) 1.25
Experience effects on brain development: possible contributions to psychopathology. J Child Psychol Psychiatry (2003) 1.22
Fragile X mental retardation protein levels increase following complex environment exposure in rat brain regions undergoing active synaptogenesis. Neurobiol Learn Mem (2005) 1.18
Stability of synaptic plasticity in the adult rat visual cortex induced by complex environment exposure. Brain Res (2004) 1.15
Correlates across the structural, functional, and molecular phenotypes of fragile X syndrome. Ment Retard Dev Disabil Res Rev (2004) 1.11
Aberrant early-phase ERK inactivation impedes neuronal function in fragile X syndrome. Proc Natl Acad Sci U S A (2008) 1.09
Postnatal binge-like alcohol exposure decreases dendritic complexity while increasing the density of mature spines in mPFC Layer II/III pyramidal neurons. Synapse (2010) 1.06
Motor learning induces astrocytic hypertrophy in the cerebellar cortex. Behav Brain Res (2007) 1.05
Fragile X mental retardation protein shifts between polyribosomes and stress granules after neuronal injury by arsenite stress or in vivo hippocampal electrode insertion. J Neurosci (2006) 1.05
Myelination of the corpus callosum in male and female rats following complex environment housing during adulthood. Brain Res (2009) 1.04
Plasticity of nonneuronal brain tissue: roles in developmental disorders. Ment Retard Dev Disabil Res Rev (2004) 1.02
Altered mossy fiber distributions in adult Fmr1 (FVB) knockout mice. Hippocampus (2002) 1.01
Mandatory " enriched" housing of laboratory animals: the need for evidence-based evaluation. ILAR J (2005) 0.98
Developmental characteristics of dendritic spines in the dentate gyrus of Fmr1 knockout mice. Brain Res (2010) 0.97
A brain adaptation view of plasticity: is synaptic plasticity an overly limited concept? Prog Brain Res (2002) 0.97
Postnatal binge-like alcohol exposure reduces spine density without affecting dendritic morphology in rat mPFC. Synapse (2008) 0.97
From bedside to bench: does mental and physical activity promote cognitive vitality in late life? Sci Aging Knowledge Environ (2006) 0.97
The effects of exercise on adolescent hippocampal neurogenesis in a rat model of binge alcohol exposure during the brain growth spurt. Brain Res (2009) 0.96
Corticosterone response to acute stress in a mouse model of Fragile X syndrome. Psychoneuroendocrinology (2006) 0.95
Early-phase ERK activation as a biomarker for metabolic status in fragile X syndrome. Am J Med Genet B Neuropsychiatr Genet (2008) 0.95
Learning-induced multiple synapse formation in rat cerebellar cortex. Neurosci Lett (2002) 0.92
Proteomic characterization of messenger ribonucleoprotein complexes bound to nontranslated or translated poly(A) mRNAs in the rat cerebral cortex. J Biol Chem (2004) 0.92
Rate and predictors of serious neurologic causes of dizziness in the emergency department. Mayo Clin Proc (2012) 0.91
Open-label riluzole in fragile X syndrome. Brain Res (2010) 0.91
A converging-methods approach to fragile X syndrome. Dev Psychobiol (2002) 0.91
Binge-like postnatal alcohol exposure triggers cortical gliogenesis in adolescent rats. J Comp Neurol (2009) 0.90
Neuropeptide Release is Impaired in a Mouse Model of Fragile X Mental Retardation Syndrome. ACS Chem Neurosci (2010) 0.89
Housing in environmental complexity following wheel running augments survival of newly generated hippocampal neurons in a rat model of binge alcohol exposure during the third trimester equivalent. Alcohol Clin Exp Res (2012) 0.85
Age-related increase in the number of oligodendrocytes is dysregulated in schizophrenia and mood disorders. Schizophr Res Treatment (2011) 0.84
Olfactory bulb mitral cell dendritic pruning abnormalities in a mouse model of the Fragile-X mental retardation syndrome: further support for FMRP's involvement in dendritic development. Brain Res Dev Brain Res (2005) 0.84
Is procedural memory relatively spared from age effects? Neurobiol Aging (2003) 0.84
Purkinje cell and cerebellar effects following developmental exposure to PCBs and/or MeHg. Neurotoxicol Teratol (2005) 0.84
Ultrastructural abnormalities of astrocytes in the hippocampus in schizophrenia and duration of illness: a postortem morphometric study. World J Biol Psychiatry (2010) 0.83
Motor skill training induces coordinated strengthening and weakening between neighboring synapses. J Neurosci (2013) 0.81
The ultrastructure of lymphocytes in schizophrenia. World J Biol Psychiatry (2007) 0.81
Deficit of pericapillary oligodendrocytes in the prefrontal cortex in schizophrenia. World J Biol Psychiatry (2008) 0.81
Cytogenesis in the adult monkey motor cortex: perivascular NG2 cells are the major adult born cell type. J Comp Neurol (2014) 0.78
Rehabilitation training using complex motor learning rescues deficits in eyeblink classical conditioning in female rats induced by binge-like neonatal alcohol exposure. Alcohol Clin Exp Res (2013) 0.78
The use of neuroimaging studies and neurological consultation to evaluate dizzy patients in the emergency department. Neurohospitalist (2013) 0.75
Effects of Fragile X syndrome and an FMR1 knockout mouse model on forebrain neuronal cell biology. Microsc Res Tech (2002) 0.75