Published in Am J Med Genet B Neuropsychiatr Genet on July 05, 2005
FMRP mediates mGluR5-dependent translation of amyloid precursor protein. PLoS Biol (2007) 2.75
Early white-matter abnormalities of the ventral frontostriatal pathway in fragile X syndrome. Dev Med Child Neurol (2009) 2.38
The state of synapses in fragile X syndrome. Neuroscientist (2009) 2.07
Murine hippocampal neurons expressing Fmr1 gene premutations show early developmental deficits and late degeneration. Hum Mol Genet (2010) 1.95
Social approach in genetically engineered mouse lines relevant to autism. Genes Brain Behav (2008) 1.94
The intense world theory - a unifying theory of the neurobiology of autism. Front Hum Neurosci (2010) 1.91
Inhibition of p21-activated kinase rescues symptoms of fragile X syndrome in mice. Proc Natl Acad Sci U S A (2007) 1.91
Circuit and plasticity defects in the developing somatosensory cortex of FMR1 knock-out mice. J Neurosci (2008) 1.72
Fragile X: translation in action. Neuropsychopharmacology (2007) 1.65
Pharmacogenetic inhibition of eIF4E-dependent Mmp9 mRNA translation reverses fragile X syndrome-like phenotypes. Cell Rep (2014) 1.55
Drosophila fragile X mental retardation protein developmentally regulates activity-dependent axon pruning. Development (2008) 1.52
Dendritic spine instability and insensitivity to modulation by sensory experience in a mouse model of fragile X syndrome. Proc Natl Acad Sci U S A (2010) 1.45
Absence of metabotropic glutamate receptor-mediated plasticity in the neocortex of fragile X mice. Proc Natl Acad Sci U S A (2007) 1.37
3D pattern of brain abnormalities in Fragile X syndrome visualized using tensor-based morphometry. Neuroimage (2006) 1.34
Therapeutic strategies in fragile X syndrome: dysregulated mGluR signaling and beyond. Neuropsychopharmacology (2011) 1.30
Altered structural and functional synaptic plasticity with motor skill learning in a mouse model of fragile X syndrome. J Neurosci (2013) 1.20
IL-6 is increased in the cerebellum of autistic brain and alters neural cell adhesion, migration and synaptic formation. J Neuroinflammation (2011) 1.17
The trouble with spines in fragile X syndrome: density, maturity and plasticity. Neuroscience (2012) 1.15
Reduced Hippocampal Activation During Recall is Associated with Elevated FMR1 mRNA and Psychiatric Symptoms in Men with the Fragile X Premutation. Brain Imaging Behav (2008) 1.14
Fragile X mental retardation protein regulates new neuron differentiation in the adult olfactory bulb. J Neurosci (2011) 1.00
Emerging pharmacotherapies for neurodevelopmental disorders. J Dev Behav Pediatr (2010) 0.99
The fragile X mental retardation protein in circadian rhythmicity and memory consolidation. Mol Neurobiol (2009) 0.99
Fragile x syndrome and autism: from disease model to therapeutic targets. J Neurodev Disord (2009) 0.98
Rescue of dendritic spine phenotype in Fmr1 KO mice with the mGluR5 antagonist AFQ056/Mavoglurant. Psychopharmacology (Berl) (2012) 0.98
Modulation of neuritogenesis by a protein implicated in X-linked mental retardation. J Neurosci (2009) 0.97
Developmental characteristics of dendritic spines in the dentate gyrus of Fmr1 knockout mice. Brain Res (2010) 0.97
Increased CYFIP1 dosage alters cellular and dendritic morphology and dysregulates mTOR. Mol Psychiatry (2014) 0.93
Activity-dependent modulation of neural circuit synaptic connectivity. Front Mol Neurosci (2009) 0.93
The molecular and genetic mechanisms of neocortex development. Clin Perinatol (2009) 0.91
Pumilio-2 function in the mouse nervous system. PLoS One (2011) 0.90
The development of cortical columns: role of Fragile X mental retardation protein. J Physiol (2009) 0.89
Abnormal dendrite and spine morphology in primary visual cortex in the CGG knock-in mouse model of the fragile X premutation. Epilepsia (2012) 0.89
Ultrastructural analysis of the functional domains in FMRP using primary hippocampal mouse neurons. Neurobiol Dis (2009) 0.89
Mouse models of the fragile X premutation and fragile X-associated tremor/ataxia syndrome. J Neurodev Disord (2014) 0.89
Modeling fragile X syndrome in the Fmr1 knockout mouse. Intractable Rare Dis Res (2014) 0.88
Dendritic spine dysgenesis in autism related disorders. Neurosci Lett (2015) 0.85
Meeting at the crossroads: common mechanisms in Fragile X and Down syndrome. Trends Neurosci (2013) 0.85
Long lasting protein synthesis- and activity-dependent spine shrinkage and elimination after synaptic depression. PLoS One (2013) 0.85
Environmental enrichment reveals effects of genotype on hippocampal spine morphologies in the mouse model of Fragile X Syndrome. Cereb Cortex (2013) 0.84
Discrimination learning and attentional set formation in a mouse model of Fragile X. Behav Neurosci (2011) 0.84
Resting-state EEG oscillatory dynamics in fragile X syndrome: abnormal functional connectivity and brain network organization. PLoS One (2014) 0.82
Increasing our understanding of human cognition through the study of Fragile X Syndrome. Dev Neurobiol (2013) 0.82
Control of spine maturation and pruning through proBDNF synthesized and released in dendrites. Mol Cell Neurosci (2015) 0.81
Input transformation by dendritic spines of pyramidal neurons. Front Neuroanat (2014) 0.81
Brief report: altered social behavior in isolation-reared Fmr1 knockout mice. J Autism Dev Disord (2013) 0.80
Activity dependent CAM cleavage and neurotransmission. Front Cell Neurosci (2015) 0.80
Augmented noncanonical BMP type II receptor signaling mediates the synaptic abnormality of fragile X syndrome. Sci Signal (2016) 0.80
Dendrite and spine modifications in autism and related neurodevelopmental disorders in patients and animal models. Dev Neurobiol (2016) 0.80
Voluntary exercise partially reverses neonatal alcohol-induced deficits in mPFC layer II/III dendritic morphology of male adolescent rats. Synapse (2015) 0.77
A Subset of Autism-Associated Genes Regulate the Structural Stability of Neurons. Front Cell Neurosci (2016) 0.76
Alterations in dendrite and spine morphology of cortical pyramidal neurons in DISC1-binding zinc finger protein (DBZ) knockout mice. Front Neuroanat (2015) 0.76
Acamprosate in a mouse model of fragile X syndrome: modulation of spontaneous cortical activity, ERK1/2 activation, locomotor behavior, and anxiety. J Neurodev Disord (2017) 0.76
Synaptic Plasticity, a Prominent Contributor to the Anxiety in Fragile X Syndrome. Neural Plast (2016) 0.75
Moving Toward Integrative, Multidimensional Research in Modern Psychiatry: Lessons Learned From Fragile X Syndrome. Biol Psychiatry (2015) 0.75
Where Environment Meets Cognition: A Focus on Two Developmental Intellectual Disability Disorders. Neural Plast (2016) 0.75
Cellular distribution of the fragile X mental retardation protein in the mouse brain. J Comp Neurol (2016) 0.75
RNA cargoes associating with FMRP reveal deficits in cellular functioning in Fmr1 null mice. Neuron (2003) 3.58
From mRNP trafficking to spine dysmorphogenesis: the roots of fragile X syndrome. Nat Rev Neurosci (2005) 3.46
Mission creep in the IRB world. Science (2006) 2.64
The use of total protein stains as loading controls: an alternative to high-abundance single-protein controls in semi-quantitative immunoblotting. J Neurosci Methods (2008) 2.54
Exercise, experience and the aging brain. Neurobiol Aging (2002) 2.44
Experience-driven brain plasticity: beyond the synapse. Neuron Glia Biol (2004) 2.27
Local protein synthesis and spine morphogenesis: Fragile X syndrome and beyond. J Neurosci (2006) 2.04
Transport of Drosophila fragile X mental retardation protein-containing ribonucleoprotein granules by kinesin-1 and cytoplasmic dynein. Proc Natl Acad Sci U S A (2004) 1.99
Environmental influences on cognitive and brain plasticity during aging. J Gerontol A Biol Sci Med Sci (2004) 1.99
Fragile X mental retardation protein is necessary for neurotransmitter-activated protein translation at synapses. Proc Natl Acad Sci U S A (2004) 1.97
Open-label treatment trial of lithium to target the underlying defect in fragile X syndrome. J Dev Behav Pediatr (2008) 1.91
Sequence of abnormal dendritic spine development in primary somatosensory cortex of a mouse model of the fragile X mental retardation syndrome. Am J Med Genet A (2005) 1.90
Achieving and maintaining cognitive vitality with aging. Mayo Clin Proc (2002) 1.81
Dendritic spine and dendritic field characteristics of layer V pyramidal neurons in the visual cortex of fragile-X knockout mice. Am J Med Genet (2002) 1.76
Application of the ABCD2 score to identify cerebrovascular causes of dizziness in the emergency department. Stroke (2012) 1.65
Pathology of layer V pyramidal neurons in the prefrontal cortex of patients with schizophrenia. Am J Psychiatry (2004) 1.61
Motor impairment in rats exposed to PCBs and methylmercury during early development. Toxicol Sci (2003) 1.59
Dendritic spine instability and insensitivity to modulation by sensory experience in a mouse model of fragile X syndrome. Proc Natl Acad Sci U S A (2010) 1.45
Hippocampal pyramidal cells in adult Fmr1 knockout mice exhibit an immature-appearing profile of dendritic spines. Brain Res (2006) 1.41
Pearls & oy-sters: the use of CT venography in Hirayama disease. Neurology (2012) 1.40
Profiling signaling peptides in single mammalian cells using mass spectrometry. Anal Chem (2006) 1.38
Altered expression of BDNF and its high-affinity receptor TrkB in response to complex motor learning and moderate exercise. Brain Res (2004) 1.33
Spatial profiling with MALDI MS: distribution of neuropeptides within single neurons. Anal Chem (2003) 1.26
Somatosensory cortical barrel dendritic abnormalities in a mouse model of the fragile X mental retardation syndrome. Brain Res (2003) 1.26
A receptor for activated C kinase is part of messenger ribonucleoprotein complexes associated with polyA-mRNAs in neurons. J Neurosci (2002) 1.25
Persistent impairment of hippocampal neurogenesis in young adult rats following early postnatal alcohol exposure. Alcohol Clin Exp Res (2007) 1.25
Altered mRNA transport, docking, and protein translation in neurons lacking fragile X mental retardation protein. Proc Natl Acad Sci U S A (2010) 1.25
Maturation time of new granule cells in the dentate gyrus of adult macaque monkeys exceeds six months. Proc Natl Acad Sci U S A (2011) 1.25
Experience effects on brain development: possible contributions to psychopathology. J Child Psychol Psychiatry (2003) 1.22
Fragile X mental retardation protein levels increase following complex environment exposure in rat brain regions undergoing active synaptogenesis. Neurobiol Learn Mem (2005) 1.18
Stability of synaptic plasticity in the adult rat visual cortex induced by complex environment exposure. Brain Res (2004) 1.15
Correlates across the structural, functional, and molecular phenotypes of fragile X syndrome. Ment Retard Dev Disabil Res Rev (2004) 1.11
Aberrant early-phase ERK inactivation impedes neuronal function in fragile X syndrome. Proc Natl Acad Sci U S A (2008) 1.09
Motor learning induces astrocytic hypertrophy in the cerebellar cortex. Behav Brain Res (2007) 1.05
Fragile X mental retardation protein shifts between polyribosomes and stress granules after neuronal injury by arsenite stress or in vivo hippocampal electrode insertion. J Neurosci (2006) 1.05
Myelination of the corpus callosum in male and female rats following complex environment housing during adulthood. Brain Res (2009) 1.04
Plasticity of nonneuronal brain tissue: roles in developmental disorders. Ment Retard Dev Disabil Res Rev (2004) 1.02
Altered mossy fiber distributions in adult Fmr1 (FVB) knockout mice. Hippocampus (2002) 1.01
Mandatory " enriched" housing of laboratory animals: the need for evidence-based evaluation. ILAR J (2005) 0.98
Developmental characteristics of dendritic spines in the dentate gyrus of Fmr1 knockout mice. Brain Res (2010) 0.97
A brain adaptation view of plasticity: is synaptic plasticity an overly limited concept? Prog Brain Res (2002) 0.97
From bedside to bench: does mental and physical activity promote cognitive vitality in late life? Sci Aging Knowledge Environ (2006) 0.97
The effects of exercise on adolescent hippocampal neurogenesis in a rat model of binge alcohol exposure during the brain growth spurt. Brain Res (2009) 0.96
Early-phase ERK activation as a biomarker for metabolic status in fragile X syndrome. Am J Med Genet B Neuropsychiatr Genet (2008) 0.95
Corticosterone response to acute stress in a mouse model of Fragile X syndrome. Psychoneuroendocrinology (2006) 0.95
Learning-induced multiple synapse formation in rat cerebellar cortex. Neurosci Lett (2002) 0.92
Proteomic characterization of messenger ribonucleoprotein complexes bound to nontranslated or translated poly(A) mRNAs in the rat cerebral cortex. J Biol Chem (2004) 0.92
Rate and predictors of serious neurologic causes of dizziness in the emergency department. Mayo Clin Proc (2012) 0.91
Open-label riluzole in fragile X syndrome. Brain Res (2010) 0.91
A converging-methods approach to fragile X syndrome. Dev Psychobiol (2002) 0.91
Binge-like postnatal alcohol exposure triggers cortical gliogenesis in adolescent rats. J Comp Neurol (2009) 0.90
Neuropeptide Release is Impaired in a Mouse Model of Fragile X Mental Retardation Syndrome. ACS Chem Neurosci (2010) 0.89
Laparoscopy or conventional open surgery for patients with ileocolonic Crohn's disease? A prospective study. Surgery (2007) 0.86
Housing in environmental complexity following wheel running augments survival of newly generated hippocampal neurons in a rat model of binge alcohol exposure during the third trimester equivalent. Alcohol Clin Exp Res (2012) 0.85
Olfactory bulb mitral cell dendritic pruning abnormalities in a mouse model of the Fragile-X mental retardation syndrome: further support for FMRP's involvement in dendritic development. Brain Res Dev Brain Res (2005) 0.84
Purkinje cell and cerebellar effects following developmental exposure to PCBs and/or MeHg. Neurotoxicol Teratol (2005) 0.84
Is procedural memory relatively spared from age effects? Neurobiol Aging (2003) 0.84
Motor skill training induces coordinated strengthening and weakening between neighboring synapses. J Neurosci (2013) 0.81
Preservation of the anal transition zone in ulcerative colitis. Long-term effects on defecatory function. J Gastrointest Surg (2007) 0.78
Rehabilitation training using complex motor learning rescues deficits in eyeblink classical conditioning in female rats induced by binge-like neonatal alcohol exposure. Alcohol Clin Exp Res (2013) 0.78
Cytogenesis in the adult monkey motor cortex: perivascular NG2 cells are the major adult born cell type. J Comp Neurol (2014) 0.78
The use of neuroimaging studies and neurological consultation to evaluate dizzy patients in the emergency department. Neurohospitalist (2013) 0.75
Effects of Fragile X syndrome and an FMR1 knockout mouse model on forebrain neuronal cell biology. Microsc Res Tech (2002) 0.75