Published in Proc Natl Acad Sci U S A on March 18, 2004
Endonucleolytic processing of covalent protein-linked DNA double-strand breaks. Nature (2005) 4.53
Crossover homeostasis in yeast meiosis. Cell (2006) 4.42
ZMM proteins during meiosis: crossover artists at work. Chromosome Res (2007) 2.17
SUMO modifications control assembly of synaptonemal complex and polycomplex in meiosis of Saccharomyces cerevisiae. Genes Dev (2006) 2.16
From early homologue recognition to synaptonemal complex formation. Chromosoma (2006) 2.15
Meiotic chromosome synapsis-promoting proteins antagonize the anti-crossover activity of sgs1. PLoS Genet (2006) 1.98
Repair of strand breaks by homologous recombination. Cold Spring Harb Perspect Biol (2013) 1.96
Does crossover interference count in Saccharomyces cerevisiae? Genetics (2004) 1.68
Synthesis-dependent strand annealing in meiosis. PLoS Biol (2007) 1.67
Gene conversion and crossing over along the 405-kb left arm of Saccharomyces cerevisiae chromosome VII. Genetics (2004) 1.65
Gradual implementation of the meiotic recombination program via checkpoint pathways controlled by global DSB levels. Mol Cell (2015) 1.54
Yeast Pch2 promotes domainal axis organization, timely recombination progression, and arrest of defective recombinosomes during meiosis. Proc Natl Acad Sci U S A (2008) 1.47
Targeted gene knockout reveals a role in meiotic recombination for ZHP-3, a Zip3-related protein in Caenorhabditis elegans. Mol Cell Biol (2004) 1.45
Numerical constraints and feedback control of double-strand breaks in mouse meiosis. Genes Dev (2013) 1.43
Pch2 links chromosome axis remodeling at future crossover sites and crossover distribution during yeast meiosis. PLoS Genet (2009) 1.32
Bioinformatic analyses implicate the collaborating meiotic crossover/chiasma proteins Zip2, Zip3, and Spo22/Zip4 in ubiquitin labeling. Proc Natl Acad Sci U S A (2005) 1.27
The diverse roles of transverse filaments of synaptonemal complexes in meiosis. Chromosoma (2006) 1.24
The multiple roles of cohesin in meiotic chromosome morphogenesis and pairing. Mol Biol Cell (2008) 1.24
Coupling meiotic chromosome axis integrity to recombination. Genes Dev (2008) 1.23
Zip4/Spo22 is required for class I CO formation but not for synapsis completion in Arabidopsis thaliana. PLoS Genet (2007) 1.23
Meiotic double-strand breaks occur once per pair of (sister) chromatids and, via Mec1/ATR and Tel1/ATM, once per quartet of chromatids. Proc Natl Acad Sci U S A (2011) 1.22
ZIP4H (TEX11) deficiency in the mouse impairs meiotic double strand break repair and the regulation of crossing over. PLoS Genet (2008) 1.18
Meiotic recombination in Drosophila females depends on chromosome continuity between genetically defined boundaries. Genetics (2004) 1.15
Chemical inactivation of cdc7 kinase in budding yeast results in a reversible arrest that allows efficient cell synchronization prior to meiotic recombination. Genetics (2006) 1.15
Meiotic recombination proteins localize to linear elements in Schizosaccharomyces pombe. Chromosoma (2006) 1.15
Recombination map of the common shrew, Sorex araneus (Eulipotyphla, Mammalia). Genetics (2008) 1.14
The pch2Delta mutation in baker's yeast alters meiotic crossover levels and confers a defect in crossover interference. PLoS Genet (2009) 1.13
Self-organization of meiotic recombination initiation: general principles and molecular pathways. Annu Rev Genet (2014) 1.10
Changing partners: moving from non-homologous to homologous centromere pairing in meiosis. Trends Genet (2008) 1.09
CRA-1 uncovers a double-strand break-dependent pathway promoting the assembly of central region proteins on chromosome axes during C. elegans meiosis. PLoS Genet (2008) 1.09
The homologous recombination system of Ustilago maydis. Fungal Genet Biol (2008) 1.07
The meiotic checkpoint network: step-by-step through meiotic prophase. Cold Spring Harb Perspect Biol (2014) 1.04
Topoisomerase II mediates meiotic crossover interference. Nature (2014) 1.04
Smc5/6 coordinates formation and resolution of joint molecules with chromosome morphology to ensure meiotic divisions. PLoS Genet (2013) 0.99
Mek1 kinase governs outcomes of meiotic recombination and the checkpoint response. Curr Biol (2010) 0.98
Excess single-stranded DNA inhibits meiotic double-strand break repair. PLoS Genet (2007) 0.98
Analysis of the proteins involved in the in vivo repair of base-base mismatches and four-base loops formed during meiotic recombination in the yeast Saccharomyces cerevisiae. Genetics (2006) 0.94
SUMOylation is required for normal development of linear elements and wild-type meiotic recombination in Schizosaccharomyces pombe. Chromosoma (2009) 0.94
Differential association of the conserved SUMO ligase Zip3 with meiotic double-strand break sites reveals regional variations in the outcome of meiotic recombination. PLoS Genet (2013) 0.94
Meiotic cohesin promotes pairing of nonhomologous centromeres in early meiotic prophase. Mol Biol Cell (2010) 0.93
Temporal characterization of homology-independent centromere coupling in meiotic prophase. PLoS One (2010) 0.93
High throughput sequencing reveals alterations in the recombination signatures with diminishing Spo11 activity. PLoS Genet (2013) 0.92
FindFoci: a focus detection algorithm with automated parameter training that closely matches human assignments, reduces human inconsistencies and increases speed of analysis. PLoS One (2014) 0.92
Meiotic chromosome synapsis in yeast can occur without spo11-induced DNA double-strand breaks. Genetics (2004) 0.89
Chromosome pairing and meiotic recombination in Neurospora crassa spo11 mutants. Curr Genet (2006) 0.89
Sustained and rapid chromosome movements are critical for chromosome pairing and meiotic progression in budding yeast. Genetics (2011) 0.87
Components of the RNAi machinery that mediate long-distance chromosomal associations are dispensable for meiotic and early somatic homolog pairing in Drosophila melanogaster. Genetics (2008) 0.87
Meiotic recombination and male infertility: from basic science to clinical reality? Asian J Androl (2011) 0.87
Relationship between incomplete synapsis and chiasma localization. Chromosoma (2009) 0.81
A surge of late-occurring meiotic double-strand breaks rescues synapsis abnormalities in spermatocytes of mice with hypomorphic expression of SPO11. Chromosoma (2015) 0.80
A few of our favorite things: Pairing, the bouquet, crossover interference and evolution of meiosis. Semin Cell Dev Biol (2016) 0.80
Pds1p is required for meiotic recombination and prophase I progression in Saccharomyces cerevisiae. Genetics (2008) 0.80
Small Rad51 and Dmc1 Complexes Often Co-occupy Both Ends of a Meiotic DNA Double Strand Break. PLoS Genet (2015) 0.80
Local chromosome context is a major determinant of crossover pathway biochemistry during budding yeast meiosis. Elife (2016) 0.79
Three distinct modes of Mec1/ATR and Tel1/ATM activation illustrate differential checkpoint targeting during budding yeast early meiosis. Mol Cell Biol (2013) 0.79
Chromosome Synapsis Alleviates Mek1-Dependent Suppression of Meiotic DNA Repair. PLoS Biol (2016) 0.79
Many functions of the meiotic cohesin. Chromosome Res (2010) 0.78
Meiotic prophase roles of Rec8 in crossover recombination and chromosome structure. Nucleic Acids Res (2016) 0.78
Reduced Crossover Interference and Increased ZMM-Independent Recombination in the Absence of Tel1/ATM. PLoS Genet (2015) 0.78
Exposure to the widely used herbicide atrazine results in deregulation of global tissue-specific RNA transcription in the third generation and is associated with a global decrease of histone trimethylation in mice. Nucleic Acids Res (2016) 0.77
Control of Meiotic Crossovers: From Double-Strand Break Formation to Designation. Annu Rev Genet (2016) 0.77
Ipl1/Aurora kinase suppresses S-CDK-driven spindle formation during prophase I to ensure chromosome integrity during meiosis. PLoS One (2013) 0.77
Ahp2 (Hop2) function in Arabidopsis thaliana (Ler) is required for stabilization of close alignment and synaptonemal complex formation except for the two short arms that contain nucleolus organizer regions. Chromosoma (2010) 0.77
Arabidopsis PCH2 Mediates Meiotic Chromosome Remodeling and Maturation of Crossovers. PLoS Genet (2015) 0.77
The epigenetic processes of meiosis in male mice are broadly affected by the widely used herbicide atrazine. BMC Genomics (2015) 0.76
Sordaria, a model system to uncover links between meiotic pairing and recombination. Semin Cell Dev Biol (2016) 0.75
Correlations between Synaptic Initiation and Meiotic Recombination: A Study of Humans and Mice. Am J Hum Genet (2015) 0.75
DMC1: a meiosis-specific yeast homolog of E. coli recA required for recombination, synaptonemal complex formation, and cell cycle progression. Cell (1992) 10.48
Meiosis-specific DNA double-strand breaks are catalyzed by Spo11, a member of a widely conserved protein family. Cell (1997) 10.32
Analysis of wild-type and rad50 mutants of yeast suggests an intimate relationship between meiotic chromosome synapsis and recombination. Cell (1990) 7.85
Meiotic chromosomes: integrating structure and function. Annu Rev Genet (1999) 7.33
An atypical topoisomerase II from Archaea with implications for meiotic recombination. Nature (1997) 7.06
Recombinational DNA double-strand breaks in mice precede synapsis. Nat Genet (2001) 6.91
Meiotic chromosomes: it takes two to tango. Genes Dev (1997) 6.90
Meiotic recombination in C. elegans initiates by a conserved mechanism and is dispensable for homologous chromosome synapsis. Cell (1998) 6.32
Temporal comparison of recombination and synaptonemal complex formation during meiosis in S. cerevisiae. Cell (1991) 6.15
ZIP1 is a synaptonemal complex protein required for meiotic chromosome synapsis. Cell (1993) 5.32
The mouse Spo11 gene is required for meiotic chromosome synapsis. Mol Cell (2000) 5.16
Chromosome synapsis defects and sexually dimorphic meiotic progression in mice lacking Spo11. Mol Cell (2000) 4.47
Meiotic prophase arrest with failure of chromosome synapsis in mice deficient for Dmc1, a germline-specific RecA homolog. Mol Cell (1998) 3.81
Zip3 provides a link between recombination enzymes and synaptonemal complex proteins. Cell (2000) 3.49
Meiotic synapsis in the absence of recombination. Science (1998) 3.48
The role of the SPO11 gene in meiotic recombination in yeast. Genetics (1985) 3.38
Rad52 associates with RPA and functions with rad55 and rad57 to assemble meiotic recombination complexes. Genes Dev (1998) 2.77
Homologous pairing is reduced but not abolished in asynaptic mutants of yeast. J Cell Biol (1994) 2.63
Meiotic chromosome behavior in spread preparations of yeast. J Cell Biol (1988) 2.61
Zip2, a meiosis-specific protein required for the initiation of chromosome synapsis. Cell (1998) 2.40
Progression of meiotic DNA replication is modulated by interchromosomal interaction proteins, negatively by Spo11p and positively by Rec8p. Genes Dev (2000) 2.34
Synaptonemal complex (SC) component Zip1 plays a role in meiotic recombination independent of SC polymerization along the chromosomes. Proc Natl Acad Sci U S A (1996) 2.29
Zip1-induced changes in synaptonemal complex structure and polycomplex assembly. J Cell Biol (1995) 2.15
Wild-type levels of Spo11-induced DSBs are required for normal single-strand resection during meiosis. Mol Cell (2002) 1.98
The Sgs1 helicase regulates chromosome synapsis and meiotic crossing over. Curr Biol (2003) 1.94
MEI4, a yeast gene required for meiotic recombination. Genetics (1989) 1.94
Rad51 immunocytology in rat and mouse spermatocytes and oocytes. Chromosoma (1997) 1.90
Genetic and morphological approaches for the analysis of meiotic chromosomes in yeast. Methods Cell Biol (1998) 1.88
Distribution of the Rad51 recombinase in human and mouse spermatocytes. EMBO J (1997) 1.82
Identification of residues in yeast Spo11p critical for meiotic DNA double-strand break formation. Mol Cell Biol (2002) 1.77
Meiotic double-strand breaks at the interface of chromosome movement, chromosome remodeling, and reductional division. Genes Dev (2003) 1.67
Localization and roles of Ski8p protein in Sordaria meiosis and delineation of three mechanistically distinct steps of meiotic homolog juxtaposition. Proc Natl Acad Sci U S A (2003) 1.60
Correlation between pairing initiation sites, recombination nodules and meiotic recombination in Sordaria macrospora. Genetics (1992) 1.59
RecA-like proteins are components of early meiotic nodules in lily. Proc Natl Acad Sci U S A (1997) 1.59
Meiotic chromosome morphology and behavior in zip1 mutants of Saccharomyces cerevisiae. Genetics (1998) 1.55
The yeast MER2 gene is required for chromosome synapsis and the initiation of meiotic recombination. Genetics (1995) 1.52
Genetic control of chromosome synapsis in yeast meiosis. Genome (1989) 1.50
Multiple roles of Spo11 in meiotic chromosome behavior. EMBO J (2000) 1.46
Functional interactions between SPO11 and REC102 during initiation of meiotic recombination in Saccharomyces cerevisiae. Genetics (2002) 1.34
The rec102 mutant of yeast is defective in meiotic recombination and chromosome synapsis. Genetics (1992) 1.32
The meotic prophase in Bombyx mori females analyzed by three dimensional reconstructions of synaptonemal complexes. Chromosoma (1976) 1.24
HO endonuclease-induced recombination in yeast meiosis resembles Spo11-induced events. Proc Natl Acad Sci U S A (2000) 1.18
The Relationship of Crossover Frequency to Synaptic Extent at Pachytene in Maize. Genetics (1965) 1.18
Two kinds of "recombination nodules" in Neurospora crassa. Genome (1989) 1.13
The temporal sequence of synaptic initiation, crossing over and synaptic completion. Genetics (1972) 1.08
Synapsis and crossing over within a paracentric inversion in the grasshopper, Camnula pellucida. Chromosoma (1968) 1.06
The relationship of crossing over to chromosome synapsis in a short paracentric inversion. Genetics (1966) 0.99
Endonucleolytic processing of covalent protein-linked DNA double-strand breaks. Nature (2005) 4.53
Crossover homeostasis in yeast meiosis. Cell (2006) 4.42
Where the crossovers are: recombination distributions in mammals. Nat Rev Genet (2004) 3.82
A hierarchical combination of factors shapes the genome-wide topography of yeast meiotic recombination initiation. Cell (2011) 3.08
Clarifying the mechanics of DNA strand exchange in meiotic recombination. Nature (2006) 3.02
Distinct properties of the XY pseudoautosomal region crucial for male meiosis. Science (2011) 2.43
Mouse HORMAD1 and HORMAD2, two conserved meiotic chromosomal proteins, are depleted from synapsed chromosome axes with the help of TRIP13 AAA-ATPase. PLoS Genet (2009) 2.15
Surveillance of different recombination defects in mouse spermatocytes yields distinct responses despite elimination at an identical developmental stage. Mol Cell Biol (2005) 2.13
Distinct DNA-damage-dependent and -independent responses drive the loss of oocytes in recombination-defective mouse mutants. Proc Natl Acad Sci U S A (2005) 2.03
Cyclin-dependent kinase directly regulates initiation of meiotic recombination. Cell (2006) 1.79
Identification of residues in yeast Spo11p critical for meiotic DNA double-strand break formation. Mol Cell Biol (2002) 1.77
Antiviral protein Ski8 is a direct partner of Spo11 in meiotic DNA break formation, independent of its cytoplasmic role in RNA metabolism. Mol Cell (2004) 1.76
Genome destabilization by homologous recombination in the germ line. Nat Rev Mol Cell Biol (2010) 1.76
Homeostatic control of recombination is implemented progressively in mouse meiosis. Nat Cell Biol (2012) 1.73
ATM controls meiotic double-strand-break formation. Nature (2011) 1.68
The E3 ubiquitin ligase Cullin 4A regulates meiotic progression in mouse spermatogenesis. Dev Biol (2011) 1.67
ATM promotes the obligate XY crossover and both crossover control and chromosome axis integrity on autosomes. PLoS Genet (2008) 1.61
Mouse TRIP13/PCH2 is required for recombination and normal higher-order chromosome structure during meiosis. PLoS Genet (2010) 1.54
Numerical constraints and feedback control of double-strand breaks in mouse meiosis. Genes Dev (2013) 1.43
Meiotic homologue alignment and its quality surveillance are controlled by mouse HORMAD1. Nat Cell Biol (2011) 1.40
Interactions between Mei4, Rec114, and other proteins required for meiotic DNA double-strand break formation in Saccharomyces cerevisiae. Chromosoma (2007) 1.35
Functional interactions between SPO11 and REC102 during initiation of meiotic recombination in Saccharomyces cerevisiae. Genetics (2002) 1.34
Evolutionary conservation of meiotic DSB proteins: more than just Spo11. Genes Dev (2010) 1.33
Synaptonemal complex formation: where does it start? Bioessays (2005) 1.25
Spatial organization and dynamics of the association of Rec102 and Rec104 with meiotic chromosomes. EMBO J (2004) 1.24
Comprehensive, fine-scale dissection of homologous recombination outcomes at a hot spot in mouse meiosis. Mol Cell (2010) 1.21
Molecular basis for enhancement of the meiotic DMC1 recombinase by RAD51 associated protein 1 (RAD51AP1). Proc Natl Acad Sci U S A (2011) 1.11
DNA polymerase beta is critical for mouse meiotic synapsis. EMBO J (2009) 1.09
Regulating the formation of DNA double-strand breaks in meiosis. Genes Dev (2008) 1.08
Gel electrophoresis assays for analyzing DNA double-strand breaks in Saccharomyces cerevisiae at various spatial resolutions. Methods Mol Biol (2009) 1.04
Scale matters: the spatial correlation of yeast meiotic DNA breaks with histone H3 trimethylation is driven largely by independent colocalization at promoters. Cell Cycle (2012) 1.02
A role for histone H2B during repair of UV-induced DNA damage in Saccharomyces cerevisiae. Genetics (2002) 0.95
Histone methylation sets the stage for meiotic DNA breaks. EMBO J (2009) 0.95
H2B (Ser10) phosphorylation is induced during apoptosis and meiosis in S. cerevisiae. Cell Cycle (2005) 0.94
Meiotic crossover hotspots contained in haplotype block boundaries of the mouse genome. Proc Natl Acad Sci U S A (2007) 0.93
The tricky path to recombining X and Y chromosomes in meiosis. Ann N Y Acad Sci (2012) 0.90
Probing meiotic recombination decisions. Dev Cell (2008) 0.90
Current management of hemorrhage from severe pelvic fractures: Results of an American Association for the Surgery of Trauma multi-institutional trial. J Trauma Acute Care Surg (2016) 0.89
Exploiting spore-autonomous fluorescent protein expression to quantify meiotic chromosome behaviors in Saccharomyces cerevisiae. Genetics (2011) 0.89
Expression of arf tumor suppressor in spermatogonia facilitates meiotic progression in male germ cells. PLoS Genet (2011) 0.88
Molecular cartography: mapping the landscape of meiotic recombination. PLoS Biol (2007) 0.88
Mice deficient for the type II topoisomerase-like DNA transesterase Spo11 show normal immunoglobulin somatic hypermutation and class switching. Eur J Immunol (2002) 0.87
Sex and the single (double-strand) break. Mol Cell (2002) 0.87
The joy of six: how to control your crossovers. Cell (2012) 0.86
Preaching about the converted: how meiotic gene conversion influences genomic diversity. Ann N Y Acad Sci (2012) 0.85
Mouse BAZ1A (ACF1) is dispensable for double-strand break repair but is essential for averting improper gene expression during spermatogenesis. PLoS Genet (2013) 0.84
End-labeling and analysis of Spo11-oligonucleotide complexes in Saccharomyces cerevisiae. Methods Mol Biol (2009) 0.84
The Rad50 hook domain regulates DNA damage signaling and tumorigenesis. Genes Dev (2014) 0.83
Modifying histones and initiating meiotic recombination; new answers to an old question. Cell (2004) 0.81
How much is enough? Control of DNA double-strand break numbers in mouse meiosis. Cell Cycle (2013) 0.80
Homologous recombination: needing to have my say. Curr Biol (2005) 0.79
Meiotic recombination initiation in and around retrotransposable elements in Saccharomyces cerevisiae. PLoS Genet (2013) 0.79
Dynamics of DOT1L localization and H3K79 methylation during meiotic prophase I in mouse spermatocytes. Chromosoma (2013) 0.79
DDK links replication and recombination in meiosis. Cell Cycle (2014) 0.76
Detection of SPO11-oligonucleotide complexes from mouse testes. Methods Mol Biol (2009) 0.76
Analysis of recombinants in female mouse meiosis. Methods Mol Biol (2013) 0.76
PCH'ing together an understanding of crossover control. PLoS Genet (2009) 0.75
Pelvic fracture pattern predicts the need for hemorrhage control intervention-Results of an AAST multi-institutional study. J Trauma Acute Care Surg (2017) 0.75
Pelvic fracture pattern predicts the need for hemorrhage control intervention -- results of a AAST multi-institutional study. J Trauma Acute Care Surg (2017) 0.75