Published in Mol Cell Biol on May 01, 2004
Exploitation of KESTREL to identify NDRG family members as physiological substrates for SGK1 and GSK3. Biochem J (2004) 3.39
Molecular mechanisms of inherited demyelinating neuropathies. Glia (2008) 1.68
Exacerbated venous thromboembolism in mice carrying a protein S K196E mutation. Blood (2015) 1.41
Ndrg4 is required for normal myocyte proliferation during early cardiac development in zebrafish. Dev Biol (2008) 1.35
Differential expression patterns of NDRG family proteins in the central nervous system. J Histochem Cytochem (2007) 1.18
NDRG4 protein-deficient mice exhibit spatial learning deficits and vulnerabilities to cerebral ischemia. J Biol Chem (2011) 1.05
Crystal structure of the human N-Myc downstream-regulated gene 2 protein provides insight into its role as a tumor suppressor. J Biol Chem (2011) 0.99
A deletion in the N-myc downstream regulated gene 1 (NDRG1) gene in Greyhounds with polyneuropathy. PLoS One (2010) 0.98
Molecular genetics of charcot-marie-tooth disease: from genes to genomes. Mol Syndromol (2012) 0.97
Bves and NDRG4 regulate directional epicardial cell migration through autocrine extracellular matrix deposition. Mol Biol Cell (2013) 0.92
Locus-wide identification of Egr2/Krox20 regulatory targets in myelin genes. J Neurochem (2010) 0.91
Identification of differentially expressed genes in carp rods and cones. Mol Vis (2008) 0.90
Functionally distinct PI 3-kinase pathways regulate myelination in the peripheral nervous system. J Cell Biol (2014) 0.87
PI3K-mediated PDGFRα signaling regulates survival and proliferation in skeletal development through p53-dependent intracellular pathways. Genes Dev (2014) 0.86
Mutation of Semaphorin-6A disrupts limbic and cortical connectivity and models neurodevelopmental psychopathology. PLoS One (2011) 0.85
Interaction of PDK1 with phosphoinositides is essential for neuronal differentiation but dispensable for neuronal survival. Mol Cell Biol (2012) 0.84
Severity and Frequency of Proximal Tubule Injury Determines Renal Prognosis. J Am Soc Nephrol (2015) 0.83
The expression and localization of N-myc downstream-regulated gene 1 in human trophoblasts. PLoS One (2013) 0.83
Hereditary motor and sensory neuropathy Lom type in a Serbian family. Acta Myol (2008) 0.82
Charcot-Marie-Tooth disease and intracellular traffic. Prog Neurobiol (2012) 0.81
NDRG1 deficiency attenuates fetal growth and the intrauterine response to hypoxic injury. Endocrinology (2013) 0.80
Ndrg1 is a T-cell clonal anergy factor negatively regulated by CD28 costimulation and interleukin-2. Nat Commun (2015) 0.79
Global gene expression analysis reveals a link between NDRG1 and vesicle transport. PLoS One (2014) 0.79
Differentiation-related gene-1 decreases Bim stability by proteasome-mediated degradation. Cancer Res (2009) 0.79
Oncogenic but non-essential role of N-myc downstream regulated gene 1 in the progression of esophageal squamous cell carcinoma. Cancer Biol Ther (2012) 0.79
Retinoic acid-activated Ndrg1a represses Wnt/β-catenin signaling to allow Xenopus pancreas, oesophagus, stomach, and duodenum specification. PLoS One (2013) 0.79
Organ-specific alternatively spliced transcript isoforms of the sunflower SF21C gene. Plant Cell Rep (2010) 0.78
Low Levels of NDRG1 in Nerve Tissue Are Predictive of Severe Paclitaxel-Induced Neuropathy. PLoS One (2016) 0.77
Cholesterol and phytosterols differentially regulate the expression of caveolin 1 and a downstream prostate cell growth-suppressor gene. Cancer Epidemiol (2010) 0.76
Effects of NDRG1 family proteins on photoreceptor outer segment morphology in zebrafish. Sci Rep (2016) 0.75
Impaired differentiation of macrophage lineage cells attenuates bone remodeling and inflammatory angiogenesis in Ndrg1 deficient mice. Sci Rep (2016) 0.75
The stretcher spontaneous neurodegenerative mutation models Charcot-Marie-Tooth disease type 4D. F1000Res (2013) 0.75
Potential role of the N-MYC downstream-regulated gene family in reprogramming cancer metabolism under hypoxia. Oncotarget (2016) 0.75
NDR proteins: lessons learned from Arabidopsis and animal cells prompt a testable hypothesis. Plant Signal Behav (2010) 0.75
Postnatal lethality and abnormal development of foregut and spleen in Ndrg4 mutant mice. Biochem Biophys Res Commun (2016) 0.75
Mitochondrial and cytoskeletal alterations are involved in the pathogenesis of hydronephrosis in ICR/Mlac-hydro mice. Int J Clin Exp Med (2015) 0.75
Neuronal Ndrg4 Is Essential for Nodes of Ranvier Organization in Zebrafish. PLoS Genet (2016) 0.75
Retracted Therapeutic DNA vaccination as a repair strategy following spinal cord injury. Cell Mol Neurobiol (2009) 0.75
Plasminogen Tochigi mice exhibit phenotypes similar to wild-type mice under experimental thrombotic conditions. PLoS One (2017) 0.75
Ndrg1 promotes adipocyte differentiation and sustains their function. Sci Rep (2017) 0.75
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The Drg-1 gene suppresses tumor metastasis in prostate cancer. Cancer Res (2003) 2.01
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Characterization and expression of three novel differentiation-related genes belong to the human NDRG gene family. Mol Cell Biochem (2002) 1.89
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Characterization of the human NDRG gene family: a newly identified member, NDRG4, is specifically expressed in brain and heart. Genomics (2001) 1.73
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N-myc-dependent repression of ndr1, a gene identified by direct subtraction of whole mouse embryo cDNAs between wild type and N-myc mutant. Mech Dev (1999) 1.53
The regulation of hypoxic genes by calcium involves c-Jun/AP-1, which cooperates with hypoxia-inducible factor 1 in response to hypoxia. Mol Cell Biol (2002) 1.48
Generation of the floxed allele of the SIP1 (Smad-interacting protein 1) gene for Cre-mediated conditional knockout in the mouse. Genesis (2002) 1.34
Identification of new genes ndr2 and ndr3 which are related to Ndr1/RTP/Drg1 but show distinct tissue specificity and response to N-myc. Biochem Biophys Res Commun (1999) 1.22
Molecular cell biology of Charcot-Marie-Tooth disease. Neurogenetics (2002) 1.17
Diagnostic value of sural nerve demyelination in chronic inflammatory demyelinating polyneuropathy. Brain (2001) 1.00
Phosphorylation of RTP, an ER stress-responsive cytoplasmic protein. Biochem Biophys Res Commun (2000) 1.00
Identification of a stress-induced protein during human trophoblast differentiation by differential display analysis. Biol Reprod (1999) 0.99
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A novel homocysteine-responsive gene, smap8, modulates mitogenesis in rat vascular smooth muscle cells. Eur J Biochem (2003) 0.96
Mouse model of GM2 activator deficiency manifests cerebellar pathology and motor impairment. Proc Natl Acad Sci U S A (1997) 0.96
Cellular distribution of NDRG1 protein in the rat kidney and brain during normal postnatal development. J Histochem Cytochem (2003) 0.89
Monounsaturated fatty acid modification of Wnt protein: its role in Wnt secretion. Dev Cell (2006) 4.89
FRETS-VWF73, a first fluorogenic substrate for ADAMTS13 assay. Br J Haematol (2005) 2.86
Triggering neural differentiation of ES cells by subtype switching of importin-alpha. Nat Cell Biol (2006) 2.64
Differential contributions of ATF6 and XBP1 to the activation of endoplasmic reticulum stress-responsive cis-acting elements ERSE, UPRE and ERSE-II. J Biochem (2004) 2.62
Zeb1 links epithelial-mesenchymal transition and cellular senescence. Development (2008) 2.55
Functional analysis of chicken Sox2 enhancers highlights an array of diverse regulatory elements that are conserved in mammals. Dev Cell (2003) 2.43
The transcription factor ZEB1 is aberrantly expressed in aggressive uterine cancers. Cancer Res (2006) 2.38
Glucose down-regulates Per1 and Per2 mRNA levels and induces circadian gene expression in cultured Rat-1 fibroblasts. J Biol Chem (2002) 2.30
Mutations and common polymorphisms in ADAMTS13 gene responsible for von Willebrand factor-cleaving protease activity. Proc Natl Acad Sci U S A (2002) 2.23
ADAMTS-13 cysteine-rich/spacer domains are functionally essential for von Willebrand factor cleavage. Blood (2003) 2.06
Wnt signaling plays an essential role in neuronal specification of the dorsal spinal cord. Genes Dev (2002) 2.01
Interplay of SOX and POU factors in regulation of the Nestin gene in neural primordial cells. Mol Cell Biol (2004) 2.00
Recent advances in thrombotic thrombocytopenic purpura. Hematology Am Soc Hematol Educ Program (2004) 1.94
The distal carboxyl-terminal domains of ADAMTS13 are required for regulation of in vivo thrombus formation. Blood (2008) 1.93
ADAMTS13 gene deletion aggravates ischemic brain damage: a possible neuroprotective role of ADAMTS13 by ameliorating postischemic hypoperfusion. Blood (2009) 1.89
Mice lacking ZFHX1B, the gene that codes for Smad-interacting protein-1, reveal a role for multiple neural crest cell defects in the etiology of Hirschsprung disease-mental retardation syndrome. Am J Hum Genet (2003) 1.88
Dlx1&2-dependent expression of Zfhx1b (Sip1, Zeb2) regulates the fate switch between cortical and striatal interneurons. Neuron (2013) 1.87
Genetic variations of regulator of G-protein signaling 2 in hypertensive patients and in the general population. J Hypertens (2005) 1.84
Evolution of the androgen receptor pathway during progression of prostate cancer. Cancer Res (2006) 1.83
Sox proteins: regulators of cell fate specification and differentiation. Development (2013) 1.82
Genotypes of vitamin K epoxide reductase, gamma-glutamyl carboxylase, and cytochrome P450 2C9 as determinants of daily warfarin dose in Japanese patients. Thromb Res (2006) 1.78
DeltaEF1 mediates TGF-beta signaling in vascular smooth muscle cell differentiation. Dev Cell (2006) 1.75
Six3-mediated auto repression and eye development requires its interaction with members of the Groucho-related family of co-repressors. Development (2002) 1.73
A systematic genome-wide screen for mutations affecting organogenesis in Medaka, Oryzias latipes. Mech Dev (2004) 1.65
Integrinalpha5-dependent fibronectin accumulation for maintenance of somite boundaries in zebrafish embryos. Dev Cell (2005) 1.63
The endothelial antigen ESAM marks primitive hematopoietic progenitors throughout life in mice. Blood (2008) 1.63
The Satb1 protein directs hematopoietic stem cell differentiation toward lymphoid lineages. Immunity (2013) 1.58
VWF73, a region from D1596 to R1668 of von Willebrand factor, provides a minimal substrate for ADAMTS-13. Blood (2003) 1.55
Efficient identification of regulatory sequences in the chicken genome by a powerful combination of embryo electroporation and genome comparison. Mech Dev (2004) 1.53
Tbx6-dependent Sox2 regulation determines neural or mesodermal fate in axial stem cells. Nature (2011) 1.50
Usefulness of anti-cyclic citrullinated peptide antibody and rheumatoid factor to detect rheumatoid arthritis in patients with systemic sclerosis. Rheumatology (Oxford) (2010) 1.46
Crystal structures of the noncatalytic domains of ADAMTS13 reveal multiple discontinuous exosites for von Willebrand factor. Proc Natl Acad Sci U S A (2009) 1.45
High-density association study and nomination of susceptibility genes for hypertension in the Japanese National Project. Hum Mol Genet (2007) 1.44
Impact of RGS2 deficiency on the therapeutic effect of telmisartan in angiotensin II-induced aortic aneurysm. Hypertens Res (2010) 1.43
Warfarin dose and the pharmacogenomics of CYP2C9 and VKORC1 - rationale and perspectives. Thromb Res (2006) 1.43
Complete deficiency in ADAMTS13 is prothrombotic, but it alone is not sufficient to cause thrombotic thrombocytopenic purpura. Blood (2005) 1.39
Identification of strain-specific variants of mouse Adamts13 gene encoding von Willebrand factor-cleaving protease. J Biol Chem (2004) 1.35
Convergence of Wnt and FGF signals in the genesis of posterior neural plate through activation of the Sox2 enhancer N-1. Development (2005) 1.35
Generation of the floxed allele of the SIP1 (Smad-interacting protein 1) gene for Cre-mediated conditional knockout in the mouse. Genesis (2002) 1.34
UV-B radiation induces epithelial tumors in mice lacking DNA polymerase eta and mesenchymal tumors in mice deficient for DNA polymerase iota. Mol Cell Biol (2006) 1.34
Fungicide activity through activation of a fungal signalling pathway. Mol Microbiol (2004) 1.33
Generation of medaka gene knockout models by target-selected mutagenesis. Genome Biol (2006) 1.30
Zebrafish hairy/enhancer of split protein links FGF signaling to cyclic gene expression in the periodic segmentation of somites. Genes Dev (2005) 1.29
Luman/CREB3 induces transcription of the endoplasmic reticulum (ER) stress response protein Herp through an ER stress response element. Mol Cell Biol (2006) 1.29
Complementary expression pattern of Zfhx1 genes Sip1 and deltaEF1 in the mouse embryo and their genetic interaction revealed by compound mutants. Dev Dyn (2006) 1.27
Zinc and calcium ions cooperatively modulate ADAMTS13 activity. J Biol Chem (2005) 1.27
Peripheral ghrelin transmits orexigenic signals through the noradrenergic pathway from the hindbrain to the hypothalamus. Cell Metab (2006) 1.26
Common variants in the ATP2B1 gene are associated with susceptibility to hypertension: the Japanese Millennium Genome Project. Hypertension (2010) 1.26
The tryptophan pathway is involved in the defense responses of rice against pathogenic infection via serotonin production. Plant J (2008) 1.24
Wnt proteins promote neuronal differentiation in neural stem cell culture. Biochem Biophys Res Commun (2004) 1.23
MEPD: a resource for medaka gene expression patterns. Bioinformatics (2005) 1.22
Herp stabilizes neuronal Ca2+ homeostasis and mitochondrial function during endoplasmic reticulum stress. J Biol Chem (2004) 1.21
Regulation of ocular lens development by Smad-interacting protein 1 involving Foxe3 activation. Development (2005) 1.20
Differential expression patterns of NDRG family proteins in the central nervous system. J Histochem Cytochem (2007) 1.18
Dual-mode modulation of Smad signaling by Smad-interacting protein Sip1 is required for myelination in the central nervous system. Neuron (2012) 1.18
Comparative genomic and expression analysis of group B1 sox genes in zebrafish indicates their diversification during vertebrate evolution. Dev Dyn (2006) 1.16
FGF2 triggers iris-derived lens regeneration in newt eye. Mech Dev (2004) 1.16
Akt mediates insulin-stimulated phosphorylation of Ndrg2: evidence for cross-talk with protein kinase C theta. J Biol Chem (2004) 1.15
B1 SOX coordinate cell specification with patterning and morphogenesis in the early zebrafish embryo. PLoS Genet (2010) 1.15
Hypoxia-inducible factor-3alpha functions as an accelerator of 3T3-L1 adipose differentiation. Biol Pharm Bull (2009) 1.14
Analysis of combinatorial effects of Wnts and Frizzleds on beta-catenin/armadillo stabilization and Dishevelled phosphorylation. Genes Cells (2005) 1.12
Ssdp1 regulates head morphogenesis of mouse embryos by activating the Lim1-Ldb1 complex. Development (2005) 1.12
Smad-interacting protein-1 (Zfhx1b) acts upstream of Wnt signaling in the mouse hippocampus and controls its formation. Proc Natl Acad Sci U S A (2007) 1.12
p53RFP, a p53-inducible RING-finger protein, regulates the stability of p21WAF1. Oncogene (2003) 1.12
Phenylpropanoid amides of serotonin accumulate in witches' broom diseased bamboo. Phytochemistry (2003) 1.11
Analysis of genetic and predisposing factors in Japanese patients with atypical hemolytic uremic syndrome. Mol Immunol (2013) 1.10
Molecular characterization of ADAMTS13 gene mutations in Japanese patients with Upshaw-Schulman syndrome. Blood (2003) 1.10
125th ENMC International Workshop: Neuromuscular disorders in the Roma (Gypsy) population, 23-25 April 2004, Naarden, The Netherlands. Neuromuscul Disord (2004) 1.09
Down-regulation of TCF8 is involved in the leukemogenesis of adult T-cell leukemia/lymphoma. Blood (2008) 1.09
Endoplasmic reticulum stress-inducible protein, Herp, enhances presenilin-mediated generation of amyloid beta-protein. J Biol Chem (2002) 1.09
Prevalence of genetic mutations in protein S, protein C and antithrombin genes in Japanese patients with deep vein thrombosis. Thromb Res (2008) 1.08
Accumulation of HDMBOA-Glc is induced by biotic stresses prior to the release of MBOA in maize leaves. Phytochemistry (2004) 1.07
Volvulus of the gall bladder diagnosed by ultrasonography, computed tomography, coronal magnetic resonance imaging and magnetic resonance cholangio-pancreatography. World J Gastroenterol (2006) 1.06
Homocysteine-induced endoplasmic reticulum protein (Herp) is up-regulated in sporadic inclusion-body myositis and in endoplasmic reticulum stress-induced cultured human muscle fibers. J Neurochem (2006) 1.06
Integrin-linked kinase associated with integrin activation. Blood (2009) 1.06
NDRG4 protein-deficient mice exhibit spatial learning deficits and vulnerabilities to cerebral ischemia. J Biol Chem (2011) 1.05
The hotei mutation of medaka in the anti-Mullerian hormone receptor causes the dysregulation of germ cell and sexual development. Proc Natl Acad Sci U S A (2007) 1.04
PAX6 and SOX2-dependent regulation of the Sox2 enhancer N-3 involved in embryonic visual system development. Genes Cells (2007) 1.04
STT3B-dependent posttranslational N-glycosylation as a surveillance system for secretory protein. Mol Cell (2012) 1.04
The zinc finger transcription factor ZFHX1A is linked to cell proliferation by Rb-E2F1. Biochem J (2007) 1.03