Published in Physiol Genomics on June 17, 2004
Associations with early-life socio-economic position in adult DNA methylation. Int J Epidemiol (2011) 2.67
Developmental origins of disease and determinants of chromatin structure: maternal diet modifies the primate fetal epigenome. J Mol Endocrinol (2008) 2.15
Intergenerational transmission of glucose intolerance and obesity by in utero undernutrition in mice. Diabetes (2008) 1.86
Prenatal environmental exposures, epigenetics, and disease. Reprod Toxicol (2011) 1.84
Organ and gestational age effects of maternal nutrient restriction on global methylation in fetal baboons. J Med Primatol (2009) 1.55
Epigenetic mechanisms in the development of type 2 diabetes. Trends Endocrinol Metab (2009) 1.46
Histone code modifications repress glucose transporter 4 expression in the intrauterine growth-restricted offspring. J Biol Chem (2008) 1.44
Epigenomics: maternal high-fat diet exposure in utero disrupts peripheral circadian gene expression in nonhuman primates. FASEB J (2010) 1.33
Epigenetics and its role in male infertility. J Assist Reprod Genet (2012) 1.27
Early life nutrition, epigenetics and programming of later life disease. Nutrients (2014) 1.18
Maternal genome-wide DNA methylation patterns and congenital heart defects. PLoS One (2011) 1.16
Developmental origins of adult disease. Pediatr Clin North Am (2009) 1.13
I'm eating for two: parental dietary effects on offspring metabolism. Cell (2015) 1.11
A maternal high-fat diet is accompanied by alterations in the fetal primate metabolome. Am J Obstet Gynecol (2009) 1.09
Developmental programming of the metabolic syndrome - critical windows for intervention. World J Diabetes (2011) 1.07
Epigenetics of programmed obesity: alteration in IUGR rat hepatic IGF1 mRNA expression and histone structure in rapid vs. delayed postnatal catch-up growth. Am J Physiol Gastrointest Liver Physiol (2010) 1.02
The intrauterine growth restriction phenotype: fetal adaptations and potential implications for later life insulin resistance and diabetes. Semin Reprod Med (2011) 1.00
The implications of DNA methylation for toxicology: toward toxicomethylomics, the toxicology of DNA methylation. Toxicol Sci (2011) 0.96
Review: Placental programming of postnatal diabetes and impaired insulin action after IUGR. Placenta (2010) 0.92
Protein restriction during pregnancy induces hypertension in adult female rat offspring--influence of oestradiol. Br J Nutr (2011) 0.91
In utero and early life exposure to diesel exhaust air pollution increases adult susceptibility to heart failure in mice. Part Fibre Toxicol (2013) 0.89
Fetal growth restriction alters transcription factor binding and epigenetic mechanisms of renal 11beta-hydroxysteroid dehydrogenase type 2 in a sex-specific manner. Am J Physiol Regul Integr Comp Physiol (2010) 0.89
Differential DNA methylation regions in cytokine and transcription factor genomic loci associate with childhood physical aggression. PLoS One (2013) 0.89
Genetic and epigenetic influences associated with intrauterine growth restriction due to in utero tobacco exposure. Pediatr Endocrinol Rev (2010) 0.89
Maternal DNA hypomethylation and congenital heart defects. Birth Defects Res A Clin Mol Teratol (2011) 0.86
Social factors and leukocyte DNA methylation of repetitive sequences: the multi-ethnic study of atherosclerosis. PLoS One (2013) 0.86
Restoring fertility in sterile childhood cancer survivors by autotransplanting spermatogonial stem cells: are we there yet? Biomed Res Int (2013) 0.85
Essential nutrient supplementation prevents heritable metabolic disease in multigenerational intrauterine growth-restricted rats. FASEB J (2014) 0.84
Reduced placental amino acid transport in response to maternal nutrient restriction in the baboon. Am J Physiol Regul Integr Comp Physiol (2015) 0.81
Epigenetic changes predisposing to type 2 diabetes in intrauterine growth retardation. Front Endocrinol (Lausanne) (2010) 0.81
The effects of diabetes on male fertility and epigenetic regulation during spermatogenesis. Asian J Androl (2015) 0.80
DNA methylation signature of childhood chronic physical aggression in T cells of both men and women. PLoS One (2014) 0.80
Intrauterine growth restriction affects hippocampal dual specificity phosphatase 5 gene expression and epigenetic characteristics. Physiol Genomics (2011) 0.79
Association of childhood chronic physical aggression with a DNA methylation signature in adult human T cells. PLoS One (2014) 0.79
Heritable IUGR and adult metabolic syndrome are reversible and associated with alterations in the metabolome following dietary supplementation of 1-carbon intermediates. FASEB J (2015) 0.79
Expression of epigenetic machinery genes is sensitive to maternal obesity and weight loss in relation to fetal growth in mice. Clin Epigenetics (2016) 0.78
Maternal diet: a modulator for epigenomic regulation during development in nonhuman primates and humans. Int J Obes Suppl (2012) 0.77
IUGR prevents IGF-1 upregulation in juvenile male mice by perturbing postnatal IGF-1 chromatin remodeling. Pediatr Res (2015) 0.75
Influence of birth weight on the renal development and kidney diseases in adulthood: experimental and clinical evidence. Int J Nephrol (2012) 0.75
Epigenetic Mechanisms of Transmission of Metabolic Disease across Generations. Cell Metab (2017) 0.75
Diet and microbiota in inflammatory bowel disease: The gut in disharmony. World J Gastroenterol (2017) 0.75
Structure and Function of Enterocyte in Intrauterine Growth Retarded Pig Neonates. Dis Markers (2017) 0.75
p53 regulates epithelial-mesenchymal transition and stem cell properties through modulating miRNAs. Nat Cell Biol (2011) 3.85
Metabolic biomarkers of increased oxidative stress and impaired methylation capacity in children with autism. Am J Clin Nutr (2004) 3.00
EGFR modulates microRNA maturation in response to hypoxia through phosphorylation of AGO2. Nature (2013) 2.67
Metabolic endophenotype and related genotypes are associated with oxidative stress in children with autism. Am J Med Genet B Neuropsychiatr Genet (2006) 2.44
Uteroplacental insufficiency increases apoptosis and alters p53 gene methylation in the full-term IUGR rat kidney. Am J Physiol Regul Integr Comp Physiol (2003) 2.31
Effects of oxygen on the development and severity of retinopathy of prematurity. J AAPOS (2013) 2.24
Developmental origins of disease and determinants of chromatin structure: maternal diet modifies the primate fetal epigenome. J Mol Endocrinol (2008) 2.15
The crosstalk of mTOR/S6K1 and Hedgehog pathways. Cancer Cell (2012) 2.02
Epithelial-mesenchymal transition induced by TNF-α requires NF-κB-mediated transcriptional upregulation of Twist1. Cancer Res (2012) 1.97
Cellular and mitochondrial glutathione redox imbalance in lymphoblastoid cells derived from children with autism. FASEB J (2009) 1.89
A mathematical model gives insights into nutritional and genetic aspects of folate-mediated one-carbon metabolism. J Nutr (2006) 1.82
Suppression of the protein tyrosine phosphatase receptor type O gene (PTPRO) by methylation in hepatocellular carcinomas. Oncogene (2003) 1.64
Uteroplacental insufficiency alters nephrogenesis and downregulates cyclooxygenase-2 expression in a model of IUGR with adult-onset hypertension. Am J Physiol Regul Integr Comp Physiol (2007) 1.62
Effects of aging, cytomegalovirus infection, and EBV infection on human B cell repertoires. J Immunol (2013) 1.51
Uteroplacental insufficiency increases p53 phosphorylation without triggering the p53-MDM2 functional circuit response in the IUGR rat kidney. Am J Physiol Regul Integr Comp Physiol (2006) 1.49
Efficacy of methylcobalamin and folinic acid treatment on glutathione redox status in children with autism. Am J Clin Nutr (2008) 1.42
Epigenetics: intrauterine growth retardation (IUGR) modifies the histone code along the rat hepatic IGF-1 gene. FASEB J (2009) 1.41
Metabolic imbalance associated with methylation dysregulation and oxidative damage in children with autism. J Autism Dev Disord (2012) 1.38
Mechanisms of DNA damage, DNA hypomethylation, and tumor progression in the folate/methyl-deficient rat model of hepatocarcinogenesis. J Nutr (2003) 1.36
Congenital heart defects and abnormal maternal biomarkers of methionine and homocysteine metabolism. Am J Clin Nutr (2005) 1.33
Long non-coding RNAs: versatile master regulators of gene expression and crucial players in cancer. Am J Transl Res (2012) 1.33
S-adenosylhomocysteine hydrolase deficiency in a human: a genetic disorder of methionine metabolism. Proc Natl Acad Sci U S A (2004) 1.32
Irreversible global DNA hypomethylation as a key step in hepatocarcinogenesis induced by dietary methyl deficiency. Mutat Res (2005) 1.31
A mathematical model of glutathione metabolism. Theor Biol Med Model (2008) 1.30
Folate deficiency disturbs hepatic methionine metabolism and promotes liver injury in the ethanol-fed micropig. Proc Natl Acad Sci U S A (2002) 1.28
APOBEC3G promotes liver metastasis in an orthotopic mouse model of colorectal cancer and predicts human hepatic metastasis. J Clin Invest (2011) 1.23
Programmed upregulation of adipogenic transcription factors in intrauterine growth-restricted offspring. Reprod Sci (2008) 1.23
In utero tobacco exposure is associated with modified effects of maternal factors on fetal growth. Am J Obstet Gynecol (2008) 1.22
A functional polymorphism in the reduced folate carrier gene and DNA hypomethylation in mothers of children with autism. Am J Med Genet B Neuropsychiatr Genet (2010) 1.19
Nutrient intake from food in children with autism. Pediatrics (2012) 1.18
Uteroplacental insufficiency induces site-specific changes in histone H3 covalent modifications and affects DNA-histone H3 positioning in day 0 IUGR rat liver. Physiol Genomics (2004) 1.17
Uteroplacental insufficiency increases visceral adiposity and visceral adipose PPARgamma2 expression in male rat offspring prior to the onset of obesity. Early Hum Dev (2010) 1.17
BikDD eliminates breast cancer initiating cells and synergizes with lapatinib for breast cancer treatment. Cancer Cell (2011) 1.17
Targeting Ras signaling through inhibition of carboxyl methylation: an unexpected property of methotrexate. Proc Natl Acad Sci U S A (2003) 1.17
Antitumor agents. 272. Structure-activity relationships and in vivo selective anti-breast cancer activity of novel neo-tanshinlactone analogues. J Med Chem (2010) 1.16
Genomic hypomethylation is specific for preneoplastic liver in folate/methyl deficient rats and does not occur in non-target tissues. Mutat Res (2004) 1.16
Prenatal origin of GATA1 mutations may be an initiating step in the development of megakaryocytic leukemia in Down syndrome. Blood (2004) 1.13
Epidermal growth factor reduces intestinal apoptosis in an experimental model of necrotizing enterocolitis. Am J Physiol Gastrointest Liver Physiol (2004) 1.12
A maternal high-fat diet modulates fetal SIRT1 histone and protein deacetylase activity in nonhuman primates. FASEB J (2012) 1.11
The developmental origins of adult disease. Curr Opin Pediatr (2009) 1.11
Long-range allosteric interactions between the folate and methionine cycles stabilize DNA methylation reaction rate. Epigenetics (2006) 1.11
Growth retardation alters the epigenetic characteristics of hepatic dual specificity phosphatase 5. FASEB J (2006) 1.10
Genome hypermethylation in Pinus silvestris of Chernobyl--a mechanism for radiation adaptation? Mutat Res (2003) 1.09
A maternal high-fat diet is accompanied by alterations in the fetal primate metabolome. Am J Obstet Gynecol (2009) 1.09
Mathematical modeling of folate metabolism: predicted effects of genetic polymorphisms on mechanisms and biomarkers relevant to carcinogenesis. Cancer Epidemiol Biomarkers Prev (2008) 1.08
National surveillance for influenza and influenza-like illness in Vietnam, 2006-2010. Vaccine (2013) 1.06
Epigenetics and the developmental origins of lung disease. Mol Genet Metab (2011) 1.05
Dextromethorphan is effective in the treatment of subacute methotrexate neurotoxicity. Pediatr Hematol Oncol (2002) 1.03
Nasal ventilation alters mesenchymal cell turnover and improves alveolarization in preterm lambs. Am J Respir Crit Care Med (2008) 1.03
Epigenetics of programmed obesity: alteration in IUGR rat hepatic IGF1 mRNA expression and histone structure in rapid vs. delayed postnatal catch-up growth. Am J Physiol Gastrointest Liver Physiol (2010) 1.02
P-glycoprotein expression in mouse brain increases with maturation. Biol Neonate (2002) 1.01
Choline-related supplements improve abnormal plasma methionine-homocysteine metabolites and glutathione status in children with cystic fibrosis. Am J Clin Nutr (2007) 1.01
Early and sustained increase in the expression of hippocampal IGF-1, but not EPO, in a developmental rodent model of traumatic brain injury. J Neurotrauma (2010) 1.01
Increased hepatic peroxisome proliferator-activated receptor-gamma coactivator-1 gene expression in a rat model of intrauterine growth retardation and subsequent insulin resistance. Endocrinology (2002) 1.01
S-adenosylhomocysteine, but not homocysteine, is toxic to yeast lacking cystathionine beta-synthase. Mol Genet Metab (2002) 1.00
Thimerosal neurotoxicity is associated with glutathione depletion: protection with glutathione precursors. Neurotoxicology (2005) 0.99
Intracellular and extracellular redox status and free radical generation in primary immune cells from children with autism. Autism Res Treat (2011) 0.99
Effects of dietary folate intake and folate binding protein-1 (Folbp1) on urinary speciation of sodium arsenate in mice. Toxicol Lett (2003) 0.98
Mechanism of reduced lung injury by high-frequency nasal ventilation in a preterm lamb model of neonatal chronic lung disease. Pediatr Res (2011) 0.98
Congenital heart defects, maternal homocysteine, smoking, and the 677 C>T polymorphism in the methylenetetrahydrofolate reductase gene: evaluating gene-environment interactions. Am J Obstet Gynecol (2006) 0.98
Uteroplacental insufficiency decreases small intestine growth and alters apoptotic homeostasis in term intrauterine growth retarded rats. Early Hum Dev (2004) 0.96
IUGR differentially alters MeCP2 expression and H3K9Me3 of the PPARγ gene in male and female rat lungs during alveolarization. Birth Defects Res A Clin Mol Teratol (2011) 0.96
A novel hTERT promoter-driven E1A therapeutic for ovarian cancer. Mol Cancer Ther (2009) 0.96
Uteroplacental insufficiency affects kidney VEGF expression in a model of IUGR with compensatory glomerular hypertrophy and hypertension. Early Hum Dev (2009) 0.95
No association between common polymorphisms in genes of folate and homocysteine metabolism and the risk of Down's syndrome among French mothers. Br J Nutr (2005) 0.95
IUGR decreases PPARγ and SETD8 Expression in neonatal rat lung and these effects are ameliorated by maternal DHA supplementation. Early Hum Dev (2010) 0.94
Congenital heart defects and maternal biomarkers of oxidative stress. Am J Clin Nutr (2005) 0.94
De novo methylation of the p16INK4A gene in early preneoplastic liver and tumors induced by folate/methyl deficiency in rats. Cancer Lett (2002) 0.94
Abnormal transmethylation/transsulfuration metabolism and DNA hypomethylation among parents of children with autism. J Autism Dev Disord (2008) 0.94
Metabolic pathology of autism in relation to redox metabolism. Biomark Med (2014) 0.94
Regulation of ubiquitination-mediated protein degradation by survival kinases in cancer. Front Oncol (2012) 0.93
Increased plasma homocysteine and S-adenosylhomocysteine and decreased methionine is associated with altered phosphatidylcholine and phosphatidylethanolamine in cystic fibrosis. J Pediatr (2003) 0.93
Uteroplacental insufficiency alters hepatic expression, phosphorylation, and activity of the glucocorticoid receptor in fetal IUGR rats. Am J Physiol Regul Integr Comp Physiol (2005) 0.92
Betaine rescue of an animal model with methylenetetrahydrofolate reductase deficiency. Biochem J (2004) 0.92
Maternal high-fat diet modulates the fetal thyroid axis and thyroid gene expression in a nonhuman primate model. Mol Endocrinol (2012) 0.92
Intrauterine growth retardation affects expression and epigenetic characteristics of the rat hippocampal glucocorticoid receptor gene. Physiol Genomics (2010) 0.92
Smurf2-mediated degradation of EZH2 enhances neuron differentiation and improves functional recovery after ischaemic stroke. EMBO Mol Med (2013) 0.92
The effects of hyperbaric oxygen therapy on oxidative stress, inflammation, and symptoms in children with autism: an open-label pilot study. BMC Pediatr (2007) 0.92
Early postnatal nutrition and programming of the preterm neonate. Nutr Rev (2011) 0.92
Phosphatidylcholine and lysophosphatidylcholine excretion is increased in children with cystic fibrosis and is associated with plasma homocysteine, S-adenosylhomocysteine, and S-adenosylmethionine. Am J Clin Nutr (2005) 0.92
Associations between maternal genotypes and metabolites implicated in congenital heart defects. Mol Genet Metab (2012) 0.92
Intrauterine growth restriction due to uteroplacental insufficiency decreased white matter and altered NMDAR subunit composition in juvenile rat hippocampi. Am J Physiol Regul Integr Comp Physiol (2009) 0.91
Cobalamin deficiency with and without neurologic abnormalities: differences in homocysteine and methionine metabolism. Blood (2002) 0.91
Neural tube defects and maternal biomarkers of folate, homocysteine, and glutathione metabolism. Birth Defects Res A Clin Mol Teratol (2006) 0.91
Abnormal Transmethylation/transsulfuration Metabolism and DNA Hypomethylation Among Parents of Children with Autism. J Autism Dev Disord (2008) 0.91
Methyl deficiency causes reduction of the methyl-CpG-binding protein, MeCP2, in rat liver. Carcinogenesis (2003) 0.90
Impact of Dnmt1 deficiency, with and without low folate diets, on tumor numbers and DNA methylation in Min mice. Carcinogenesis (2003) 0.89
Fetal growth restriction alters transcription factor binding and epigenetic mechanisms of renal 11beta-hydroxysteroid dehydrogenase type 2 in a sex-specific manner. Am J Physiol Regul Integr Comp Physiol (2010) 0.89
Molecular determinants of lung development. Ann Am Thorac Soc (2013) 0.89
Molecular alterations in hepatocarcinogenesis induced by dietary methyl deficiency. Mol Nutr Food Res (2011) 0.88
Methionine-deficient diet induces post-transcriptional downregulation of cystathionine β-synthase. Nutrition (2009) 0.88
Studies of methionine cycle intermediates (SAM, SAH), DNA methylation and the impact of folate deficiency on tumor numbers in Min mice. Carcinogenesis (2002) 0.88
IUGR decreases elastin mRNA expression in the developing rat lung and alters elastin content and lung compliance in the mature rat lung. Physiol Genomics (2011) 0.88
IGF alters jejunal glucose transporter expression and serum glucose levels in immature rats. Am J Physiol Regul Integr Comp Physiol (2002) 0.88