Published in Pharmacol Res on September 22, 1992
Stat3 as an oncogene. Cell (1999) 17.39
The cyclin D1 gene is a target of the beta-catenin/LEF-1 pathway. Proc Natl Acad Sci U S A (1999) 10.75
NF-kappaB controls cell growth and differentiation through transcriptional regulation of cyclin D1. Mol Cell Biol (1999) 5.98
All-trans retinoic acid as a differentiation therapy for acute promyelocytic leukemia. I. Clinical results. Blood (1990) 4.36
p53 mutations in human lymphoid malignancies: association with Burkitt lymphoma and chronic lymphocytic leukemia. Proc Natl Acad Sci U S A (1991) 3.69
The MLL recombinome of acute leukemias in 2013. Leukemia (2013) 2.55
Cyclin D1 is required for transformation by activated Neu and is induced through an E2F-dependent signaling pathway. Mol Cell Biol (2000) 2.47
Simian virus 40-like DNA sequences in human pleural mesothelioma. Oncogene (1994) 2.21
Direct acetylation of the estrogen receptor alpha hinge region by p300 regulates transactivation and hormone sensitivity. J Biol Chem (2001) 2.16
Inhibition of cyclin D1 kinase activity is associated with E2F-mediated inhibition of cyclin D1 promoter activity through E2F and Sp1. Mol Cell Biol (1998) 2.10
Transcriptional regulation of the cyclin D1 promoter by STAT5: its involvement in cytokine-dependent growth of hematopoietic cells. EMBO J (1999) 2.10
NF-kappaB and cell-cycle regulation: the cyclin connection. Cytokine Growth Factor Rev (2001) 1.91
Induction of cyclin D1 by simian virus 40 small tumor antigen. Proc Natl Acad Sci U S A (1996) 1.86
Trophic effects of purines in neurons and glial cells. Prog Neurobiol (1999) 1.82
Integration of Rac-dependent regulation of cyclin D1 transcription through a nuclear factor-kappaB-dependent pathway. J Biol Chem (1999) 1.82
The cyclins and cyclin-dependent kinase inhibitors in hormonal regulation of proliferation and differentiation. Endocr Rev (1999) 1.78
The integrin-linked kinase regulates the cyclin D1 gene through glycogen synthase kinase 3beta and cAMP-responsive element-binding protein-dependent pathways. J Biol Chem (2000) 1.77
Cyclin D1 binds the androgen receptor and regulates hormone-dependent signaling in a p300/CBP-associated factor (P/CAF)-dependent manner. Mol Endocrinol (2001) 1.71
Retracted Altered repertoire of endogenous immunoglobulin gene expression in transgenic mice containing a rearranged mu heavy chain gene. Cell (1986) 1.66
Strontium ranelate: dose-dependent effects in established postmenopausal vertebral osteoporosis--a 2-year randomized placebo controlled trial. J Clin Endocrinol Metab (2002) 1.57
Angiotensin II activation of cyclin D1-dependent kinase activity. J Biol Chem (1996) 1.51
Combined duodenal and colonic necrosis. An unusual sequela of caustic ingestion. J Clin Gastroenterol (1994) 1.49
Amyloid beta-peptide stimulates nitric oxide production in astrocytes through an NFkappaB-dependent mechanism. Proc Natl Acad Sci U S A (1998) 1.48
Rho family GTPases regulate mammary epithelium cell growth and metastasis through distinguishable pathways. Mol Med (2001) 1.46
Inhibition of cellular proliferation through IkappaB kinase-independent and peroxisome proliferator-activated receptor gamma-dependent repression of cyclin D1. Mol Cell Biol (2001) 1.46
Improving adherence to and persistence with oral therapy of osteoporosis. Osteoporos Int (2015) 1.46
Negative regulation of the Wnt-beta-catenin pathway by the transcriptional repressor HBP1. EMBO J (2001) 1.45
Disruption of transforming growth factor-beta signaling through beta-spectrin ELF leads to hepatocellular cancer through cyclin D1 activation. Oncogene (2007) 1.44
A new recurrent and specific cryptic translocation, t(5;14)(q35;q32), is associated with expression of the Hox11L2 gene in T acute lymphoblastic leukemia. Leukemia (2001) 1.43
Down-regulation of cyclin D1 by transcriptional repression in MCF-7 human breast carcinoma cells induced by flavopiridol. Cancer Res (1999) 1.40
Metabotropic glutamate receptor subtypes as targets for neuroprotective drugs. J Cereb Blood Flow Metab (2001) 1.38
TGFbeta and PTHrP control chondrocyte proliferation by activating cyclin D1 expression. Mol Biol Cell (2001) 1.37
The gonadotropin alpha-gene contains multiple protein binding domains that interact to modulate basal and cAMP-responsive transcription. J Biol Chem (1988) 1.33
Activating transcription factor 3 induces DNA synthesis and expression of cyclin D1 in hepatocytes. J Biol Chem (2001) 1.31
All-trans retinoic acid in acute promyelocytic leukemias. II. In vitro studies: structure-function relationship. Blood (1990) 1.30
The cyclin D1 gene is transcriptionally repressed by caveolin-1. J Biol Chem (2000) 1.28
SPRED1 germline mutations caused a neurofibromatosis type 1 overlapping phenotype. J Med Genet (2009) 1.28
Rat astroglial P2Z (P2X7) receptors regulate intracellular calcium and purine release. Neuroreport (1996) 1.26
Expression of CD34 and CD7 on human T-cell acute lymphoblastic leukemia discriminates functionally heterogeneous cell populations. Leukemia (2011) 1.16
Inactivation of tumor suppressor genes, p53 and Rb1, in plasma cell dyscrasias. Leukemia (1994) 1.16
A mutation in the follicle-stimulating hormone receptor occurs frequently in human ovarian sex cord tumors. J Clin Endocrinol Metab (1997) 1.14
Phalangeal osteosonogrammetry study: age-related changes, diagnostic sensitivity, and discrimination power. The Phalangeal Osteosonogrammetry Study Group. J Bone Miner Res (2000) 1.13
Neuroprotection by glial metabotropic glutamate receptors is mediated by transforming growth factor-beta. J Neurosci (1998) 1.13
Rat cultured astrocytes release guanine-based purines in basal conditions and after hypoxia/hypoglycemia. Glia (1999) 1.06
Protein kinase Cdelta inhibition of S-phase transition in capillary endothelial cells involves the cyclin-dependent kinase inhibitor p27(Kip1). J Biol Chem (1999) 1.05
c-Jun represses transcription of the human chorionic gonadotropin alpha and beta genes through distinct types of CREs. J Biol Chem (1994) 1.02
Involvement of astrocytes in purine-mediated reparative processes in the brain. Int J Dev Neurosci (2001) 1.01
The thyrotropin (TSH) receptor transmembrane domain mutation (Pro556-Leu) in the hypothyroid hyt/hyt mouse results in plasma membrane targeting but defective TSH binding. Endocrinology (1995) 1.01
Cell-cycle dysregulation in breast cancer: breast cancer therapies targeting the cell cycle. Front Biosci (2000) 1.00
Retracted Neuroprotection mediated by glial group-II metabotropic glutamate receptors requires the activation of the MAP kinase and the phosphatidylinositol-3-kinase pathways. J Neurochem (2001) 1.00
Retinoic acid therapy for promyelocytic leukaemia. Lancet (1989) 1.00
The retinoic acid receptor alpha gene is rearranged in retinoic acid-sensitive promyelocytic leukemias. Leukemia (1990) 1.00
Testosterone amplifies excitotoxic damage of cultured oligodendrocytes. J Neurochem (2004) 0.99
Experience with laparoscopic adrenalectomy in pediatric patients. J Pediatr Surg (2002) 0.98
P2Y1 and cysteinyl leukotriene receptors mediate purine and cysteinyl leukotriene co-release in primary cultures of rat microglia. Int J Immunopathol Pharmacol (2005) 0.98
Cultured astrocyte proliferation induced by extracellular guanosine involves endogenous adenosine and is raised by the co-presence of microglia. Glia (2000) 0.97
Regulation of the human chorionic gonadotropin alpha- and beta-subunit promoters by AP-2. J Biol Chem (1997) 0.97
The majority of myeloid-antigen-positive (My+) childhood B-cell precursor acute lymphoblastic leukaemias express TEL-AML1 fusion transcripts. Br J Haematol (1997) 0.95
t(5;14)/HOX11L2-positive T-cell acute lymphoblastic leukemia. A collaborative study of the Groupe Français de Cytogénétique Hématologique (GFCH). Leukemia (2003) 0.94
Optimized gene transfer into human primary leukemic T cell with NOD-SCID/leukemia-initiating cell activity. Leukemia (2009) 0.93
Regional changes in the metabolite profile after long-term hypoxia-ischemia in brains of young and aged rats: a quantitative proton MRS study. Neurobiol Aging (2005) 0.92
Activator protein-2 mediates transcriptional activation of the CYP11A1 gene by interaction with Sp1 rather than binding to DNA. Mol Endocrinol (1999) 0.92
Stimulation of the P-450 side chain cleavage enzyme (CYP11A1) promoter through ras- and Ets-2-signaling pathways. Mol Endocrinol (1996) 0.91
Downregulation of cyclin D1 alters cdk 4- and cdk 2-specific phosphorylation of retinoblastoma protein. Mol Cell Biol Res Commun (2000) 0.91
S-plasty for various anal lesions. Am J Surg (1992) 0.90
Inhaled nitric oxide in congenital diaphragmatic hernia. J Pediatr Surg (1994) 0.89
Vascular endothelial growth factor enhances in vitro proliferation and osteogenic differentiation of human dental pulp stem cells. J Biol Regul Homeost Agents (2011) 0.88
Bone disorders in patients with chronic liver disease awaiting liver transplantation. Transplant Proc (2010) 0.88
Opposite influence of the metabotropic glutamate receptor subtypes mGlu3 and -5 on astrocyte proliferation in culture. Glia (1997) 0.88
Activation of P2X(7) receptors stimulates the expression of P2Y(2) receptor mRNA in astrocytes cultured from rat brain. Int J Immunopathol Pharmacol (2007) 0.88
A new TaqI polymorphism in the p53 gene. Nucleic Acids Res (1992) 0.88
Papillary cystic neoplasm of the pancreas: a report of three pediatric cases and literature review. J Pediatr Surg (1998) 0.87
All-trans retinoic acid modulates the retinoic acid receptor-alpha in promyelocytic cells. J Clin Invest (1991) 0.87
Guanosine protects human neuroblastoma cells from oxidative stress and toxicity induced by Amyloid-beta peptide oligomers. J Biol Regul Homeost Agents (2010) 0.85
Ras regulation of cyclin D1 promoter. Methods Enzymol (2001) 0.85
Interaction between A1 adenosine and class II metabotropic glutamate receptors in the regulation of purine and glutamate release from rat hippocampal slices. J Neurochem (1996) 0.84
Effects of exogenous ATP and related analogues on the proliferation rate of dissociated primary cultures of rat astrocytes. J Neurosci Res (1994) 0.83
P2Y2 receptor up-regulation induced by guanosine or UTP in rat brain cultured astrocytes. Int J Immunopathol Pharmacol (2006) 0.83
Adrenocorticotropin induction of stress-activated protein kinase in the adrenal cortex in vivo. J Biol Chem (1997) 0.83
Distinct adjacent protein-binding domains in the glycoprotein hormone alpha gene interact independently with a cAMP-responsive enhancer. J Biol Chem (1989) 0.83
[Transfusion in sickle cell anemia]. Pathol Biol (Paris) (1999) 0.83
Guanosine promotes proliferation of neural stem cells through cAMP-CREB pathway. J Biol Regul Homeost Agents (2013) 0.82