Published in Curr Opin Rheumatol on May 01, 2004
T-cell and natural killer-cell large granular lymphocyte leukemia neoplasias. Leuk Lymphoma (2011) 2.37
Blocking of interleukin-17 during reactivation of experimental arthritis prevents joint inflammation and bone erosion by decreasing RANKL and interleukin-1. Am J Pathol (2005) 2.26
Abatacept inhibits progression of structural damage in rheumatoid arthritis: results from the long-term extension of the AIM trial. Ann Rheum Dis (2007) 1.86
Imbalance of regulatory T cells in human autoimmune diseases. Immunology (2006) 1.64
Activator protein 1 (Fos/Jun) functions in inflammatory bone and skin disease. Arthritis Res Ther (2008) 1.54
A clinical exploratory study with itolizumab, an anti-CD6 monoclonal antibody, in patients with rheumatoid arthritis. Results Immunol (2012) 1.30
Unchecked CD70 expression on T cells lowers threshold for T cell activation in rheumatoid arthritis. J Immunol (2007) 1.22
Long term safety of etanercept in elderly subjects with rheumatic diseases. Ann Rheum Dis (2005) 1.19
Geranylgeranyltransferase type I (GGTase-I) deficiency hyperactivates macrophages and induces erosive arthritis in mice. J Clin Invest (2011) 1.05
T-cell activation via CD26 and caveolin-1 in rheumatoid synovium. Mod Rheumatol (2006) 0.92
Immune effects of therapy with Adalimumab in patients with rheumatoid arthritis. Clin Exp Immunol (2005) 0.91
Immunologic changes in frail older adults. Transl Med UniSa (2014) 0.87
Immunological evaluation of rheumatoid arthritis patients treated with itolizumab. MAbs (2015) 0.83
Soluble PD-1 aggravates progression of collagen-induced arthritis through Th1 and Th17 pathways. Arthritis Res Ther (2015) 0.81
T cell tolerance induced by therapeutic antibodies. Philos Trans R Soc Lond B Biol Sci (2005) 0.81
Rosmarinic acid induces apoptosis of activated T cells from rheumatoid arthritis patients via mitochondrial pathway. J Clin Immunol (2006) 0.81
Pathomechanisms in rheumatoid arthritis--time for a string theory? J Clin Invest (2006) 0.77
Varying expression of four genes sharing a common regulatory sequence may differentiate rheumatoid arthritis from ageing effects on the CD4(+) lymphocytes. Immunology (2010) 0.76
Association of c-Jun gene polymorphism with susceptibility to systemic lupus erythematosus in a Chinese population. DNA Cell Biol (2012) 0.75
Abatacept: the evidence for its place in the treatment of rheumatoid arthritis. Core Evid (2008) 0.75
S-propargyl-cysteine attenuates inflammatory response in rheumatoid arthritis by modulating the Nrf2-ARE signaling pathway. Redox Biol (2016) 0.75
Central nervous system demyelination associated with etanercept in a 51 years old woman. Libyan J Med (2007) 0.75
Payers Have Biologic Alternative for Patients With Moderate to Severe Rheumatoid Arthritis Who Do Not Respond to Other DMARD Therapies. Biotechnol Healthc (2006) 0.75
[T cell-dependent monocyte activation, TNFalpha and apolipoprotein A-I in autoimmunity and inflammation]. Z Rheumatol (2005) 0.75
Inhibition of microRNA-34a ameliorates murine collagen-induced arthritis. Exp Ther Med (2017) 0.75
The influence of age on T cell generation and TCR diversity. J Immunol (2005) 4.36
Infliximab for maintenance of glucocorticosteroid-induced remission of giant cell arteritis: a randomized trial. Ann Intern Med (2007) 3.81
Treatment of giant cell arteritis using induction therapy with high-dose glucocorticoids: a double-blind, placebo-controlled, randomized prospective clinical trial. Arthritis Rheum (2006) 3.64
Clinical practice. Giant-cell arteritis and polymyalgia rheumatica. N Engl J Med (2014) 3.46
Inflammation, immunity, and hypertension. Hypertension (2010) 3.43
T cell subset-specific susceptibility to aging. Clin Immunol (2008) 2.42
T cell development and receptor diversity during aging. Curr Opin Immunol (2005) 2.29
Decline in miR-181a expression with age impairs T cell receptor sensitivity by increasing DUSP6 activity. Nat Med (2012) 2.19
Understanding immunosenescence to improve responses to vaccines. Nat Immunol (2013) 2.09
Prognostic markers of radiographic progression in early rheumatoid arthritis. Arthritis Rheum (2004) 2.08
Aging and T-cell diversity. Exp Gerontol (2007) 2.06
Phosphofructokinase deficiency impairs ATP generation, autophagy, and redox balance in rheumatoid arthritis T cells. J Exp Med (2013) 1.96
Rheumatoid arthritis. Immunol Rev (2005) 1.94
Vessel-specific Toll-like receptor profiles in human medium and large arteries. Circulation (2008) 1.91
Modulation of CD28 expression with anti-tumor necrosis factor alpha therapy in rheumatoid arthritis. Arthritis Rheum (2005) 1.88
Th17 and Th1 T-cell responses in giant cell arteritis. Circulation (2010) 1.88
Pathogen-sensing plasmacytoid dendritic cells stimulate cytotoxic T-cell function in the atherosclerotic plaque through interferon-alpha. Circulation (2006) 1.77
Interleukin 12 induces T-cell recruitment into the atherosclerotic plaque. Circ Res (2006) 1.77
BLyS and APRIL in rheumatoid arthritis. J Clin Invest (2005) 1.75
Regulation of T cell receptor signaling by activation-induced zinc influx. J Exp Med (2011) 1.73
T-cell-mediated lysis of endothelial cells in acute coronary syndromes. Circulation (2002) 1.72
Activation of arterial wall dendritic cells and breakdown of self-tolerance in giant cell arteritis. J Exp Med (2004) 1.70
Inhibition and genetic ablation of the B7/CD28 T-cell costimulation axis prevents experimental hypertension. Circulation (2010) 1.68
Premature telomeric loss in rheumatoid arthritis is genetically determined and involves both myeloid and lymphoid cell lineages. Proc Natl Acad Sci U S A (2003) 1.65
T cell recognition and killing of vascular smooth muscle cells in acute coronary syndrome. Circ Res (2006) 1.62
Epigenetic regulation of killer immunoglobulin-like receptor expression in T cells. Blood (2009) 1.62
Homeostatic control of T-cell generation in neonates. Blood (2003) 1.62
Aging, autoimmunity and arthritis: T-cell senescence and contraction of T-cell repertoire diversity - catalysts of autoimmunity and chronic inflammation. Arthritis Res Ther (2003) 1.61
Immune activation caused by vascular oxidation promotes fibrosis and hypertension. J Clin Invest (2015) 1.55
Telomerase insufficiency in rheumatoid arthritis. Proc Natl Acad Sci U S A (2009) 1.54
Deficiency of the DNA repair enzyme ATM in rheumatoid arthritis. J Exp Med (2009) 1.54
NADPH oxidase deficiency underlies dysfunction of aged CD8+ Tregs. J Clin Invest (2016) 1.53
TRAIL-expressing T cells induce apoptosis of vascular smooth muscle cells in the atherosclerotic plaque. J Exp Med (2006) 1.48
T-cell senescence: a culprit of immune abnormalities in chronic inflammation and persistent infection. Trends Mol Med (2004) 1.47
Synergistic proinflammatory effects of the antiviral cytokine interferon-alpha and Toll-like receptor 4 ligands in the atherosclerotic plaque. Circulation (2007) 1.47
Surgical pathology of noninfectious ascending aortitis: a study of 45 cases with emphasis on an isolated variant. Am J Surg Pathol (2006) 1.42
Rheumatoid arthritis is an independent risk factor for multi-vessel coronary artery disease: a case control study. Arthritis Res Ther (2005) 1.38
Developments in the scientific understanding of rheumatoid arthritis. Arthritis Res Ther (2009) 1.38
CD8 T cells are required for the formation of ectopic germinal centers in rheumatoid synovitis. J Exp Med (2002) 1.38
Toll-like receptors 4 and 5 induce distinct types of vasculitis. Circ Res (2009) 1.37
Vessel wall-embedded dendritic cells induce T-cell autoreactivity and initiate vascular inflammation. Circ Res (2008) 1.35
Functional profile of activated dendritic cells in unstable atherosclerotic plaque. Basic Res Cardiol (2006) 1.34
Simvastatin suppresses endotoxin-induced upregulation of toll-like receptors 4 and 2 in vivo. Atherosclerosis (2006) 1.26
Defective proliferative capacity and accelerated telomeric loss of hematopoietic progenitor cells in rheumatoid arthritis. Arthritis Rheum (2008) 1.25
Inhibitory CD8+ T cells in autoimmune disease. Hum Immunol (2008) 1.23
DNA-dependent protein kinase catalytic subunit mediates T-cell loss in rheumatoid arthritis. EMBO Mol Med (2010) 1.23
Stimulatory killer Ig-like receptors modulate T cell activation through DAP12-dependent and DAP12-independent mechanisms. J Immunol (2004) 1.23
Telomeres and immunological diseases of aging. Gerontology (2009) 1.22
Unchecked CD70 expression on T cells lowers threshold for T cell activation in rheumatoid arthritis. J Immunol (2007) 1.22
CD28 loss in senescent CD4+ T cells: reversal by interleukin-12 stimulation. Blood (2002) 1.21
Telomere dysfunction, autoimmunity and aging. Aging Dis (2011) 1.20
Immune aging and autoimmunity. Cell Mol Life Sci (2012) 1.19
Trapping of misdirected dendritic cells in the granulomatous lesions of giant cell arteritis. Am J Pathol (2002) 1.19
Selective activation of the c-Jun NH2-terminal protein kinase signaling pathway by stimulatory KIR in the absence of KARAP/DAP12 in CD4+ T cells. J Exp Med (2003) 1.18
Signaling pathways in aged T cells - a reflection of T cell differentiation, cell senescence and host environment. Semin Immunol (2012) 1.18
The impact of HLA-DRB1 genes on extra-articular disease manifestations in rheumatoid arthritis. Arthritis Res Ther (2005) 1.17
Telomeres, immune aging and autoimmunity. Exp Gerontol (2006) 1.17
Dendritic cells in atherosclerotic disease. Clin Immunol (2009) 1.17
Formation of the killer Ig-like receptor repertoire on CD4+CD28null T cells. J Immunol (2002) 1.15
De novo expression of killer immunoglobulin-like receptors and signaling proteins regulates the cytotoxic function of CD4 T cells in acute coronary syndromes. Circ Res (2003) 1.15
Chronic inflammation and aging: DNA damage tips the balance. Curr Opin Immunol (2012) 1.13
Blocking the NOTCH pathway inhibits vascular inflammation in large-vessel vasculitis. Circulation (2011) 1.12
Molecular basis for the loss of CD28 expression in senescent T cells. J Biol Chem (2002) 1.11
Regulatory T cells and the immune aging process: a mini-review. Gerontology (2013) 1.10
CD8+CD45RA+CCR7+FOXP3+ T cells with immunosuppressive properties: a novel subset of inducible human regulatory T cells. J Immunol (2012) 1.10
Uncoupling of T-cell effector functions by inhibitory killer immunoglobulin-like receptors. Blood (2006) 1.09
TLR-mediated induction of negative regulatory ligands on dendritic cells. J Mol Med (Berl) (2008) 1.09
The janus head of T cell aging - autoimmunity and immunodeficiency. Front Immunol (2013) 1.09
Signal inhibition by the dual-specific phosphatase 4 impairs T cell-dependent B-cell responses with age. Proc Natl Acad Sci U S A (2012) 1.08
T cell costimulation by fractalkine-expressing synoviocytes in rheumatoid arthritis. Arthritis Rheum (2005) 1.08
Lymphotoxin beta-mediated stimulation of synoviocytes in rheumatoid arthritis. Arthritis Rheum (2004) 1.08
Clinicopathologic correlations in giant cell arteritis: a retrospective study of 107 cases. Ophthalmology (2009) 1.08
The treatment of giant cell arteritis. Rev Neurol Dis (2008) 1.08
Distinct transcriptional control mechanisms of killer immunoglobulin-like receptors in natural killer (NK) and in T cells. J Biol Chem (2005) 1.07
ERK-dependent T cell receptor threshold calibration in rheumatoid arthritis. J Immunol (2009) 1.06
Cell-based immunotherapy with suppressor CD8+ T cells in rheumatoid arthritis. J Immunol (2005) 1.05
Immune aging and rheumatoid arthritis. Rheum Dis Clin North Am (2010) 1.05
Toll-like receptors in giant cell arteritis. Clin Immunol (2005) 1.04
Association of HLA-C3 and smoking with vasculitis in patients with rheumatoid arthritis. Arthritis Rheum (2006) 1.01
Thrombospondin 2 functions as an endogenous regulator of angiogenesis and inflammation in rheumatoid arthritis. Am J Pathol (2004) 1.01
Epigenetic mechanisms of age-dependent KIR2DL4 expression in T cells. J Leukoc Biol (2008) 1.00
IL-7- and IL-15-mediated TCR sensitization enables T cell responses to self-antigens. J Immunol (2013) 0.99
Tissue trafficking patterns of effector memory CD4+ T cells in rheumatoid arthritis. Arthritis Rheum (2005) 0.99
Treating autoimmune disease by targeting CD8(+) T suppressor cells. Expert Opin Biol Ther (2009) 0.98
Fractalkine mediates T cell-dependent proliferation of synovial fibroblasts in rheumatoid arthritis. Arthritis Rheum (2007) 0.97
Synoviocyte-mediated expansion of inflammatory T cells in rheumatoid synovitis is dependent on CD47-thrombospondin 1 interaction. J Immunol (2003) 0.97
The double life of NK receptors: stimulation or co-stimulation? Trends Immunol (2004) 0.97
Giant cell arteritis: immune and vascular aging as disease risk factors. Arthritis Res Ther (2011) 0.95
The diagnosis of giant cell arteritis. Rev Neurol Dis (2007) 0.95
Vascular damage in giant cell arteritis. Autoimmunity (2009) 0.95
Genetics of rheumatoid arthritis: Is there a pattern predicting extraarticular manifestations? Arthritis Rheum (2004) 0.94
Synoviocyte stimulation by the LFA-1-intercellular adhesion molecule-2-Ezrin-Akt pathway in rheumatoid arthritis. J Immunol (2008) 0.94
Dynamic immune cell accumulation during flow-induced atherogenesis in mouse carotid artery: an expanded flow cytometry method. Arterioscler Thromb Vasc Biol (2012) 0.93
Mechanisms of immunosenescence: lessons from models of accelerated immune aging. Ann N Y Acad Sci (2012) 0.93
T-cell co-stimulatory pathways in autoimmunity. Arthritis Res Ther (2008) 0.91
Macrophages in vascular inflammation--From atherosclerosis to vasculitis. Autoimmunity (2015) 0.91
Costimulatory pathways in rheumatoid synovitis and T-cell senescence. Ann N Y Acad Sci (2005) 0.90
Inflammation and cardiac outcome. Curr Opin Infect Dis (2011) 0.90
B cells as a therapeutic target in autoimmune disease. Arthritis Res Ther (2003) 0.90
Age-dependent signature of metallothionein expression in primary CD4 T cell responses is due to sustained zinc signaling. Rejuvenation Res (2008) 0.89