Published in Invest Ophthalmol Vis Sci on May 01, 2004
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Effect of gene therapy on visual function in Leber's congenital amaurosis. N Engl J Med (2008) 15.30
Gene therapy of X-linked severe combined immunodeficiency by use of a pseudotyped gammaretroviral vector. Lancet (2004) 5.43
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Retinal ganglion cell apoptosis in glaucoma is related to intraocular pressure and IOP-induced effects on extracellular matrix. Invest Ophthalmol Vis Sci (2005) 2.02
Diagnostic accuracy of microbial keratitis with in vivo scanning laser confocal microscopy. Br J Ophthalmol (2010) 1.96
The drusenlike phenotype in aging Ccl2-knockout mice is caused by an accelerated accumulation of swollen autofluorescent subretinal macrophages. Invest Ophthalmol Vis Sci (2009) 1.84
Repair of the degenerate retina by photoreceptor transplantation. Proc Natl Acad Sci U S A (2012) 1.79
Gene therapy for retinitis pigmentosa and Leber congenital amaurosis caused by defects in AIPL1: effective rescue of mouse models of partial and complete Aipl1 deficiency using AAV2/2 and AAV2/8 vectors. Hum Mol Genet (2009) 1.76
Long-term preservation of cones and improvement in visual function following gene therapy in a mouse model of leber congenital amaurosis caused by guanylate cyclase-1 deficiency. Hum Gene Ther (2011) 1.68
Regulation of PCNA and cyclin D1 expression and epithelial morphogenesis by the ZO-1-regulated transcription factor ZONAB/DbpA. Mol Cell Biol (2006) 1.65
Decreased expression of peroxiredoxins in Fuchs' endothelial dystrophy. Invest Ophthalmol Vis Sci (2008) 1.55
Defining the integration capacity of embryonic stem cell-derived photoreceptor precursors. Stem Cells (2012) 1.52
Long-term and age-dependent restoration of visual function in a mouse model of CNGB3-associated achromatopsia following gene therapy. Hum Mol Genet (2011) 1.47
Gene replacement therapy rescues photoreceptor degeneration in a murine model of Leber congenital amaurosis lacking RPGRIP. Invest Ophthalmol Vis Sci (2005) 1.47
Autologous transplantation of the retinal pigment epithelium and choroid in the treatment of neovascular age-related macular degeneration. Ophthalmology (2007) 1.44
AAV-mediated expression targeting of rod and cone photoreceptors with a human rhodopsin kinase promoter. Invest Ophthalmol Vis Sci (2007) 1.44
Long-term survival of photoreceptors transplanted into the adult murine neural retina requires immune modulation. Stem Cells (2010) 1.42
A randomised placebo-controlled trial of topical steroid in presumed viral conjunctivitis. Br J Ophthalmol (2011) 1.39
Mechanisms of mitotic inhibition in corneal endothelium: contact inhibition and TGF-beta2. Invest Ophthalmol Vis Sci (2002) 1.32
Permanent phenotypic correction of hemophilia B in immunocompetent mice by prenatal gene therapy. Blood (2004) 1.30
AAV-Mediated gene transfer slows photoreceptor loss in the RCS rat model of retinitis pigmentosa. Mol Ther (2003) 1.26
Quality of vision and graft thickness in deep anterior lamellar and penetrating corneal allografts. Am J Ophthalmol (2006) 1.26
HIF-1alpha and HIF-2alpha are differentially activated in distinct cell populations in retinal ischaemia. PLoS One (2010) 1.24
Function of indoleamine 2,3-dioxygenase in corneal allograft rejection and prolongation of allograft survival by over-expression. Eur J Immunol (2006) 1.24
Topographical characterization of cone photoreceptors and the area centralis of the canine retina. Mol Vis (2008) 1.23
Prospects for retinal gene replacement therapy. Trends Genet (2009) 1.20
Differential modulation of retinal degeneration by Ccl2 and Cx3cr1 chemokine signalling. PLoS One (2012) 1.19
Relationship among oxidative stress, DNA damage, and proliferative capacity in human corneal endothelium. Invest Ophthalmol Vis Sci (2008) 1.18
Comparative analysis of progenitor cells isolated from the iris, pars plana, and ciliary body of the adult porcine eye. Stem Cells (2007) 1.17
Age differences in cyclin-dependent kinase inhibitor expression and rb hyperphosphorylation in human corneal endothelial cells. Invest Ophthalmol Vis Sci (2006) 1.15
Inflammatory cytokines induce apoptosis of corneal endothelium through nitric oxide. Invest Ophthalmol Vis Sci (2004) 1.13
Adult ciliary epithelial cells, previously identified as retinal stem cells with potential for retinal repair, fail to differentiate into new rod photoreceptors. Stem Cells (2010) 1.13
In contrast to AAV-mediated Cntf expression, AAV-mediated Gdnf expression enhances gene replacement therapy in rodent models of retinal degeneration. Mol Ther (2006) 1.13
Long-term evaluation of retinal function in Prph2Rd2/Rd2 mice following AAV-mediated gene replacement therapy. J Gene Med (2003) 1.12
Brief report: self-organizing neuroepithelium from human pluripotent stem cells facilitates derivation of photoreceptors. Stem Cells (2013) 1.11
Lentiviral vector integration profiles differ in rodent postmitotic tissues. Mol Ther (2011) 1.06
Marked inhibition of retinal neovascularization in rats following soluble-flt-1 gene transfer. J Gene Med (2004) 1.05
Subretinal delivery of adeno-associated virus serotype 2 results in minimal immune responses that allow repeat vector administration in immunocompetent mice. J Gene Med (2009) 1.04
Increased clusterin expression in Fuchs' endothelial dystrophy. Invest Ophthalmol Vis Sci (2008) 1.04
Decreasing expression of the G1-phase inhibitors, p21Cip1 and p16INK4a, promotes division of corneal endothelial cells from older donors. Mol Vis (2010) 1.00
Assessment and in vivo scoring of murine experimental autoimmune uveoretinitis using optical coherence tomography. PLoS One (2013) 0.99
The tight junction associated signalling proteins ZO-1 and ZONAB regulate retinal pigment epithelium homeostasis in mice. PLoS One (2010) 0.99
Modulation of costimulation by CD28 and CD154 alters the kinetics and cellular characteristics of corneal allograft rejection. Invest Ophthalmol Vis Sci (2003) 0.99
Potential of human umbilical cord blood mesenchymal stem cells to heal damaged corneal endothelium. Mol Vis (2012) 0.98
Subconjunctival bevacizumab induces regression of corneal neovascularisation: a pilot randomised placebo-controlled double-masked trial. Br J Ophthalmol (2012) 0.98
Local administration of an adeno-associated viral vector expressing IL-10 reduces monocyte infiltration and subsequent photoreceptor damage during experimental autoimmune uveitis. Mol Ther (2005) 0.97
Migration, integration and maturation of photoreceptor precursors following transplantation in the mouse retina. Stem Cells Dev (2014) 0.96
Generation of activated sialoadhesin-positive microglia during retinal degeneration. Invest Ophthalmol Vis Sci (2003) 0.95
Retinal dystrophies and gene therapy. Eur J Pediatr (2011) 0.94
Inhibition of ocular neovascularization by hedgehog blockade. Mol Ther (2005) 0.94
3-hydroxykynurenine suppresses CD4+ T-cell proliferation, induces T-regulatory-cell development, and prolongs corneal allograft survival. Invest Ophthalmol Vis Sci (2011) 0.93
Minocycline delays photoreceptor death in the rds mouse through a microglia-independent mechanism. Exp Eye Res (2004) 0.93
Hsp90 inhibition protects against inherited retinal degeneration. Hum Mol Genet (2013) 0.93
Absence of chx10 causes neural progenitors to persist in the adult retina. Invest Ophthalmol Vis Sci (2006) 0.93
Arginine depletion as a mechanism for the immune privilege of corneal allografts. Eur J Immunol (2011) 0.93
Age-related gene response of human corneal endothelium to oxidative stress and DNA damage. Invest Ophthalmol Vis Sci (2011) 0.92
Effects of SOV-induced phosphatase inhibition and expression of protein tyrosine phosphatases in rat corneal endothelial cells. Exp Eye Res (2005) 0.92
Long-term reversal of chronic anemia using a hypoxia-regulated erythropoietin gene therapy. Blood (2002) 0.91
Gene transfer of an engineered zinc finger protein enhances the anti-angiogenic defense system. Mol Ther (2007) 0.91
Bilateral nerve alterations in a unilateral experimental neurotrophic keratopathy model: a lateral conjunctival approach for trigeminal axotomy. PLoS One (2013) 0.90
Successful gene therapy in older Rpe65-deficient dogs following subretinal injection of an adeno-associated vector expressing RPE65. Hum Gene Ther (2013) 0.90
Induced pluripotent stem cell technology for generating photoreceptors. Regen Med (2011) 0.89
Gene therapy for ocular angiogenesis. Clin Sci (Lond) (2003) 0.89
Regenerative medicine: DIY eye. Nature (2011) 0.89
Induction of replication in human corneal endothelial cells by E2F2 transcription factor cDNA transfer. Invest Ophthalmol Vis Sci (2005) 0.89
CD200R signaling inhibits pro-angiogenic gene expression by macrophages and suppresses choroidal neovascularization. Sci Rep (2013) 0.88
GFAP-driven GFP expression in activated mouse Müller glial cells aligning retinal blood vessels following intravitreal injection of AAV2/6 vectors. PLoS One (2010) 0.88
Dendritic cell modification as a route to inhibiting corneal graft rejection by the indirect pathway of allorecognition. Eur J Immunol (2013) 0.88
Endogenous erythropoietin protects neuroretinal function in ischemic retinopathy. Am J Pathol (2012) 0.87
Leber congenital amaurosis associated with AIPL1: challenges in ascribing disease causation, clinical findings, and implications for gene therapy. PLoS One (2012) 0.87
CNTF gene transfer protects ganglion cells in rat retinae undergoing focal injury and branch vessel occlusion. Exp Eye Res (2006) 0.86
Effect of glaucoma on corneal graft survival according to indication for penetrating keratoplasty. Am J Ophthalmol (2010) 0.86
Dominant cone-rod dystrophy: a mouse model generated by gene targeting of the GCAP1/Guca1a gene. PLoS One (2011) 0.85
Protein tyrosine phosphatase-1B (PTP1B) helps regulate EGF-induced stimulation of S-phase entry in human corneal endothelial cells. Mol Vis (2008) 0.85
Immune modulation in corneal transplantation. Transplant Rev (Orlando) (2008) 0.85
Sirolimus and mycophenolate as combination prophylaxis in corneal transplant recipients at high rejection risk. Am J Ophthalmol (2010) 0.83
Neuroprotective gene therapy for the treatment of inherited retinal degeneration. Curr Gene Ther (2007) 0.82
Gene therapeutic prospects in early onset of severe retinal dystrophy: restoration of vision in RPE65 Briard dogs using an AAV serotype 4 vector that specifically targets the retinal pigmented epithelium. Bull Mem Acad R Med Belg (2006) 0.82
Comparative analysis of the retinal potential of embryonic stem cells and amniotic fluid-derived stem cells. Stem Cells Dev (2010) 0.81
Differential effects of costimulatory pathway modulation on corneal allograft survival. Invest Ophthalmol Vis Sci (2006) 0.81
A peptide encoded by exon 6 of VEGF (EG3306) inhibits VEGF-induced angiogenesis in vitro and ischaemic retinal neovascularisation in vivo. Biochem Biophys Res Commun (2003) 0.81
p27kip1 Antisense-induced proliferative activity of rat corneal endothelial cells. Invest Ophthalmol Vis Sci (2004) 0.81
High-titer stocks of adeno-associated virus from replicating amplicons and herpes vectors. Methods Mol Med (2002) 0.79
Von Hippel-Lindau protein in the RPE is essential for normal ocular growth and vascular development. Development (2012) 0.79
Local vs. systemic mononuclear phagocytes in age-related macular degeneration and their regulation by CCL2-CCR2 and CX3CL1-CX3CR1 chemokine signalling. Adv Exp Med Biol (2012) 0.78
Suppression of the allogeneic response by the anti-allergy drug N-(3,4-dimethoxycinnamonyl) anthranilic acid results from T-cell cycle arrest. Immunology (2013) 0.77
The relevance of chemokine signalling in modulating inherited and age-related retinal degenerations. Adv Exp Med Biol (2014) 0.77
Spectral sensitivity measurements reveal partial success in restoring missing rod function with gene therapy. J Vis (2015) 0.76
Gene augmentation trials using the Rpe65-deficient dog: contributions towards development and refinement of human clinical trials. Adv Exp Med Biol (2012) 0.76
Antidepressant medication use in palliative care. Am J Hosp Palliat Care (2006) 0.75
Risks of gene therapy should be weighed against lack of alternatives for many diseases. BMJ (2005) 0.75
Reply to comment on "Ccl2, Cx3cr1 and Ccl2/Cx3cr1 chemokine deficiencies are not sufficient to cause age-related retinal degeneration" by Luhmann et al. (Exp. Eye Res. 107, February 2013, 80-87). Exp Eye Res (2013) 0.75
Characterisation of the phenotype and function of monocyte-derived dendritic cells in allergic conjunctiva. Br J Ophthalmol (2010) 0.75
Longitudinal Changes to Tight Junction Expression and Endothelial Cell Integrity in a Mouse Model of Sterile Corneal Inflammation. Invest Ophthalmol Vis Sci (2016) 0.75
Isolation and culture of adult ciliary epithelial cells, previously identified as retinal stem cells, and retinal progenitor cells. Curr Protoc Stem Cell Biol (2011) 0.75