PubRank

Raffaella Sordella

Author PubWeight™ 113.57‹?›

Top papers

Rank Title Journal Year PubWeight™‹?›
1 Activating mutations in the epidermal growth factor receptor underlying responsiveness of non-small-cell lung cancer to gefitinib. N Engl J Med 2004 71.08
2 Identification of genotype-correlated sensitivity to selective kinase inhibitors by using high-throughput tumor cell line profiling. Proc Natl Acad Sci U S A 2007 8.23
3 Irreversible inhibitors of the EGF receptor may circumvent acquired resistance to gefitinib. Proc Natl Acad Sci U S A 2005 6.82
4 Amplification of MET may identify a subset of cancers with extreme sensitivity to the selective tyrosine kinase inhibitor PHA-665752. Proc Natl Acad Sci U S A 2006 5.23
5 Inherited susceptibility to lung cancer may be associated with the T790M drug resistance mutation in EGFR. Nat Genet 2005 4.00
6 A rapid and scalable system for studying gene function in mice using conditional RNA interference. Cell 2011 3.69
7 TGF-beta IL-6 axis mediates selective and adaptive mechanisms of resistance to molecular targeted therapy in lung cancer. Proc Natl Acad Sci U S A 2010 2.72
8 DLC1 is a chromosome 8p tumor suppressor whose loss promotes hepatocellular carcinoma. Genes Dev 2008 2.60
9 Epidermal growth factor receptor mutants from human lung cancers exhibit enhanced catalytic activity and increased sensitivity to gefitinib. Cancer Res 2007 2.30
10 DOCK4, a GTPase activator, is disrupted during tumorigenesis. Cell 2003 1.94
11 Towards patient-based cancer therapeutics. Nat Biotechnol 2010 1.63
12 SHP-2 positively regulates myogenesis by coupling to the Rho GTPase signaling pathway. Mol Cell Biol 2004 1.53
13 p190 Rho-GTPase activating protein associates with plexins and it is required for semaphorin signalling. J Cell Sci 2005 1.31
14 Increased prevalence of EGFR-mutant lung cancer in women and in East Asian populations: analysis of estrogen-related polymorphisms. Clin Cancer Res 2008 1.12
15 An FF domain-dependent protein interaction mediates a signaling pathway for growth factor-induced gene expression. Mol Cell 2005 1.05
16 Metabolic alterations in lung cancer-associated fibroblasts correlated with increased glycolytic metabolism of the tumor. Mol Cancer Res 2013 0.97
17 Distinct but overlapping functions for the closely related p190 RhoGAPs in neural development. Dev Neurosci 2006 0.87
18 TAp73 is essential for germ cell adhesion and maturation in testis. J Cell Biol 2014 0.86
19 TP53 exon-6 truncating mutations produce separation of function isoforms with pro-tumorigenic functions. Elife 2017 0.75