Irreversible inhibitors of the EGF receptor may circumvent acquired resistance to gefitinib.

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Published in Proc Natl Acad Sci U S A on May 16, 2005

Authors

Eunice L Kwak1, Raffaella Sordella, Daphne W Bell, Nadia Godin-Heymann, Ross A Okimoto, Brian W Brannigan, Patricia L Harris, David R Driscoll, Panos Fidias, Thomas J Lynch, Sridhar K Rabindran, John P McGinnis, Allan Wissner, Sreenath V Sharma, Kurt J Isselbacher, Jeffrey Settleman, Daniel A Haber

Author Affiliations

1: Center for Molecular Therapeutics, Massachusetts General Hospital Cancer Center, Harvard Medical School, Charlestown, MA 02129, USA.

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