White matter hyperintensities are associated with impairment of memory, attention, and global cognitive performance in older stroke patients.

PubWeight™: 1.26‹?› | Rank: Top 10%

🔗 View Article (PMID 15118186)

Published in Stroke on April 29, 2004

Authors

Emma J Burton1, Rose Anne Kenny, John O'Brien, Sally Stephens, Michael Bradbury, Elise Rowan, Raj Kalaria, Michael Firbank, Keith Wesnes, Clive Ballard

Author Affiliations

1: Institute for Ageing and Health, Newcastle General Hospital, Newcastle, UK.

Articles citing this

Vascular risk factors and dementia: how to move forward? Neurology (2009) 2.97

Spatial distribution of white-matter hyperintensities in Alzheimer disease, cerebral amyloid angiopathy, and healthy aging. Stroke (2008) 2.12

Cerebral white matter: neuroanatomy, clinical neurology, and neurobehavioral correlates. Ann N Y Acad Sci (2008) 1.85

Vascular basis for brain degeneration: faltering controls and risk factors for dementia. Nutr Rev (2010) 1.44

Correlations between MRI white matter lesion location and executive function and episodic memory. Neurology (2011) 1.43

Functional impact of white matter hyperintensities in cognitively normal elderly subjects. Arch Neurol (2010) 1.36

Quantification of myelin loss in frontal lobe white matter in vascular dementia, Alzheimer's disease, and dementia with Lewy bodies. Acta Neuropathol (2010) 1.31

White matter hyperintensities as a predictor of neuropsychological deficits post-stroke. J Neurol Neurosurg Psychiatry (2005) 1.24

Differential impact of cerebral white matter changes, diabetes, hypertension and stroke on cognitive performance among non-disabled elderly. The LADIS study. J Neurol Neurosurg Psychiatry (2007) 1.17

The association of magnetic resonance imaging measures with cognitive function in a biracial population sample. Arch Neurol (2010) 1.05

White matter hyperintensity and cognitive functioning in the racial and ethnic minority cohort of the Framingham Heart Study. Neuroepidemiology (2010) 0.90

Blood pressure and cognition among older adults: a meta-analysis. Arch Clin Neuropsychol (2013) 0.90

Measurement of brain activation during an upright stepping reaction task using functional near-infrared spectroscopy. Hum Brain Mapp (2012) 0.86

The relation of dietary choline to cognitive performance and white-matter hyperintensity in the Framingham Offspring Cohort. Am J Clin Nutr (2011) 0.86

Lessons from a mouse model characterizing features of vascular cognitive impairment with white matter changes. J Aging Res (2011) 0.86

Association of white matter hyperintensities and gray matter volume with cognition in older individuals without cognitive impairment. Brain Struct Funct (2015) 0.83

Frontal white matter hyperintensities, clasmatodendrosis and gliovascular abnormalities in ageing and post-stroke dementia. Brain (2015) 0.83

Applying Automated MR-Based Diagnostic Methods to the Memory Clinic: A Prospective Study. J Alzheimers Dis (2015) 0.81

Subcortical hyperintensity volumetrics in Alzheimer's disease and normal elderly in the Sunnybrook Dementia Study: correlations with atrophy, executive function, mental processing speed, and verbal memory. Alzheimers Res Ther (2014) 0.81

Stroke injury, cognitive impairment and vascular dementia. Biochim Biophys Acta (2016) 0.80

Effects of a Visual Distracter Task on the Gait of Elderly versus Young Persons. Curr Gerontol Geriatr Res (2011) 0.79

The independent contributions of cognitive impairment and neuropsychiatric symptoms to everyday function in older adults. Clin Neuropsychol (2014) 0.78

The impact of cerebrovascular aging on vascular cognitive impairment and dementia. Ageing Res Rev (2016) 0.77

Impact of Strategically Located White Matter Hyperintensities on Cognition in Memory Clinic Patients with Small Vessel Disease. PLoS One (2016) 0.75

Whole blood gene expression and white matter Hyperintensities. Mol Neurodegener (2017) 0.75

Burden and Predictors of Poststroke Cognitive Impairment in a Sample of Ghanaian Stroke Survivors. J Stroke Cerebrovasc Dis (2017) 0.75

Low-grade albuminuria is associated with poor memory performance in the nondemented Chinese elderly with type 2 diabetes. Metab Brain Dis (2017) 0.75

Articles by these authors

Revising the definition of Alzheimer's disease: a new lexicon. Lancet Neurol (2010) 8.74

Sertraline or mirtazapine for depression in dementia (HTA-SADD): a randomised, multicentre, double-blind, placebo-controlled trial. Lancet (2011) 6.09

Donepezil and memantine for moderate-to-severe Alzheimer's disease. N Engl J Med (2012) 5.64

Multiple populations of artemisinin-resistant Plasmodium falciparum in Cambodia. Nat Genet (2013) 5.22

Efficacy of treating pain to reduce behavioural disturbances in residents of nursing homes with dementia: cluster randomised clinical trial. BMJ (2011) 4.37

Vascular cognitive impairment. Lancet Neurol (2003) 3.73

Effect of enhanced psychosocial care on antipsychotic use in nursing home residents with severe dementia: cluster randomised trial. BMJ (2006) 3.69

Patients with recurrent falls attending Accident & Emergency benefit from multifactorial intervention--a randomised controlled trial. Age Ageing (2005) 3.42

Neuropathology of dementia in Parkinson's disease: a prospective, community-based study. Ann Neurol (2005) 3.31

Sensitivity and specificity of dopamine transporter imaging with 123I-FP-CIT SPECT in dementia with Lewy bodies: a phase III, multicentre study. Lancet Neurol (2007) 3.25

Prion-like propagation of mutant superoxide dismutase-1 misfolding in neuronal cells. Proc Natl Acad Sci U S A (2011) 3.23

Multifactorial intervention after a fall in older people with cognitive impairment and dementia presenting to the accident and emergency department: randomised controlled trial. BMJ (2003) 2.71

Dementia with Lewy bodies. Lancet Neurol (2004) 2.66

Changes in white matter as determinant of global functional decline in older independent outpatients: three year follow-up of LADIS (leukoaraiosis and disability) study cohort. BMJ (2009) 2.51

Telomere length predicts poststroke mortality, dementia, and cognitive decline. Ann Neurol (2006) 2.50

Guidelines on management (diagnosis and treatment) of syncope--update 2004. Europace (2004) 2.47

Dietary factors and low-grade inflammation in relation to overweight and obesity. Br J Nutr (2011) 2.16

Memantine in patients with Parkinson's disease dementia or dementia with Lewy bodies: a double-blind, placebo-controlled, multicentre trial. Lancet Neurol (2009) 2.10

Guidelines on management (diagnosis and treatment) of syncope-update 2004. Executive Summary. Eur Heart J (2004) 2.01

Carotid sinus hypersensitivity in asymptomatic older persons: implications for diagnosis of syncope and falls. Arch Intern Med (2006) 1.94

Prospective follow-up study between 3 and 15 months after stroke: improvements and decline in cognitive function among dementia-free stroke survivors >75 years of age. Stroke (2003) 1.89

Ischemic basis for deep white matter hyperintensities in major depression: a neuropathological study. Arch Gen Psychiatry (2002) 1.88

Memantine for dementia in adults older than 40 years with Down's syndrome (MEADOWS): a randomised, double-blind, placebo-controlled trial. Lancet (2012) 1.88

Cognitive impairment in patients with Parkinson's disease: diagnosis, biomarkers, and treatment. Lancet Neurol (2012) 1.86

Potentiation of electrical and chemical synaptic transmission mediated by endocannabinoids. Neuron (2007) 1.85

A frailty instrument for primary care: findings from the Survey of Health, Ageing and Retirement in Europe (SHARE). BMC Geriatr (2010) 1.71

Sensory stimulation in dementia. BMJ (2002) 1.71

Chewing gum selectively improves aspects of memory in healthy volunteers. Appetite (2002) 1.65

Improving quality of life for people with dementia in care homes: making psychosocial interventions work. Br J Psychiatry (2012) 1.65

Towards defining the neuropathological substrates of vascular dementia. J Neurol Sci (2004) 1.63

Do older pedestrians have enough time to cross roads in Dublin? A critique of the Traffic Management Guidelines based on clinical research findings. Age Ageing (2009) 1.61

Visual hallucinations in dementia with Lewy bodies: transcranial magnetic stimulation study. Br J Psychiatry (2011) 1.58

CSF amyloid-beta and tau proteins, and cognitive performance, in early and untreated Parkinson's disease: the Norwegian ParkWest study. J Neurol Neurosurg Psychiatry (2010) 1.55

Use of drugs with anticholinergic effect and impact on cognition in Parkinson's disease: a cohort study. J Neurol Neurosurg Psychiatry (2009) 1.54

Quetiapine and rivastigmine and cognitive decline in Alzheimer's disease: randomised double blind placebo controlled trial. BMJ (2005) 1.54

Characterizing mild cognitive impairment in incident Parkinson disease: the ICICLE-PD study. Neurology (2013) 1.53

Risk of rapid global functional decline in elderly patients with severe cerebral age-related white matter changes: the LADIS study. Arch Intern Med (2007) 1.52

Neuropsychiatric symptoms in Alzheimer's disease: past progress and anticipation of the future. Alzheimers Dement (2013) 1.51

CSF amyloid β38 as a novel diagnostic marker for dementia with Lewy bodies. J Neurol Neurosurg Psychiatry (2010) 1.50

Frailty and cognitive impairment--a review of the evidence and causal mechanisms. Ageing Res Rev (2013) 1.50

Drop attacks in older adults: systematic assessment has a high diagnostic yield. J Am Geriatr Soc (2005) 1.47

Antipsychotics for people with dementia. BMJ (2008) 1.45

Implementation of a telepharmacy service to provide round-the-clock medication order review by pharmacists. Am J Health Syst Pharm (2010) 1.43

Dopamine-stimulated dephosphorylation of connexin 36 mediates AII amacrine cell uncoupling. J Neurosci (2009) 1.43

Drug repositioning for Alzheimer's disease. Nat Rev Drug Discov (2012) 1.42

Effective interventions to prevent falls in older people. Br J Gen Pract (2002) 1.42

The prevalence of falls in older persons paced for atrioventricular block and sick sinus syndrome. Am J Geriatr Cardiol (2003) 1.41

2001-2011: A Decade of the LADIS (Leukoaraiosis And DISability) Study: What Have We Learned about White Matter Changes and Small-Vessel Disease? Cerebrovasc Dis (2011) 1.40

Anti-psychotic drug use in older people. Age Ageing (2002) 1.39

Management of behavioral problems in Alzheimer's disease. Int Psychogeriatr (2010) 1.38

Dopamine transporter loss visualized with FP-CIT SPECT in the differential diagnosis of dementia with Lewy bodies. Arch Neurol (2004) 1.33

Prevalence and severity of gait disorders in Alzheimer's and non-Alzheimer's dementias. J Am Geriatr Soc (2005) 1.31

Incidence and prediction of falls in dementia: a prospective study in older people. PLoS One (2009) 1.31

Cognitive associations of subcortical white matter lesions in older people. Ann N Y Acad Sci (2002) 1.29

Clinical practice with anti-dementia drugs: a consensus statement from British Association for Psychopharmacology. J Psychopharmacol (2006) 1.29

Orthostatic hypotension in Parkinson's disease: association with cognitive decline? Int J Geriatr Psychiatry (2006) 1.29

Hypertension is a potential risk factor for vascular dementia: systematic review. Int J Geriatr Psychiatry (2010) 1.28

Systematic review and meta-analysis show that dementia with Lewy bodies is a visual-perceptual and attentional-executive dementia. Dement Geriatr Cogn Disord (2003) 1.27

Determining the minimum clinically important differences for outcomes in the DOMINO trial. Int J Geriatr Psychiatry (2010) 1.26

Parkinson's disease dementia and dementia with Lewy bodies: different aspects of one entity. Int Psychogeriatr (2009) 1.26

A review of cognitive impairment and cerebral metabolite abnormalities in patients with hepatitis C infection. AIDS (2005) 1.25

Salvia for dementia therapy: review of pharmacological activity and pilot tolerability clinical trial. Pharmacol Biochem Behav (2003) 1.25

The effect of staff training on agitation and use of restraint in nursing home residents with dementia: a single-blind, randomized controlled trial. J Clin Psychiatry (2010) 1.25

Longitudinal cognitive decline in subcortical ischemic vascular disease--the LADIS Study. Cerebrovasc Dis (2009) 1.25

Frequency and case identification of dementia with Lewy bodies using the revised consensus criteria. Dement Geriatr Cogn Disord (2008) 1.24

Aromas of rosemary and lavender essential oils differentially affect cognition and mood in healthy adults. Int J Neurosci (2003) 1.23

Effects of hypertension on attention, memory, and executive function in older adults. Health Psychol (2003) 1.23

Assessment and treatment of pain in people with dementia. Nat Rev Neurol (2012) 1.22

Subjective memory complaints, white-matter lesions, depressive symptoms, and cognition in elderly patients. Am J Geriatr Psychiatry (2005) 1.21

Optimised anaesthesia to reduce post operative cognitive decline (POCD) in older patients undergoing elective surgery, a randomised controlled trial. PLoS One (2012) 1.21

Diagnostic criteria for vascular cognitive disorders: a VASCOG statement. Alzheimer Dis Assoc Disord (2014) 1.21

Age, hypertension, and lacunar stroke are the major determinants of the severity of age-related white matter changes. The LADIS (Leukoaraiosis and Disability in the Elderly) Study. Cerebrovasc Dis (2006) 1.20

Inflammation in Alzheimer's disease: relevance to pathogenesis and therapy. Alzheimers Res Ther (2010) 1.20

A comparison of (99m)Tc-HMPAO SPET changes in dementia with Lewy bodies and Alzheimer's disease using statistical parametric mapping. Eur J Nucl Med Mol Imaging (2002) 1.19

The frailty index in Europeans: association with age and mortality. Age Ageing (2012) 1.17

Using timed up-and-go to identify frail members of the older population. J Gerontol A Biol Sci Med Sci (2012) 1.17

Differential impact of cerebral white matter changes, diabetes, hypertension and stroke on cognitive performance among non-disabled elderly. The LADIS study. J Neurol Neurosurg Psychiatry (2007) 1.17

Seasonal variation of serum vitamin D and the effect of vitamin D supplementation in Irish community-dwelling older people. Age Ageing (2010) 1.17

Low macular pigment optical density is associated with lower cognitive performance in a large, population-based sample of older adults. Neurobiol Aging (2013) 1.16

Caregiver preference for rivastigmine patches versus capsules for the treatment of Alzheimer disease. Neurology (2007) 1.16

Connexin 35/36 is phosphorylated at regulatory sites in the retina. Vis Neurosci (2007) 1.15

Efficacy of memantine for agitation in Alzheimer's dementia: a randomised double-blind placebo controlled trial. PLoS One (2012) 1.14

Brief psychosocial therapy for the treatment of agitation in Alzheimer disease (the CALM-AD trial). Am J Geriatr Psychiatry (2009) 1.14

Association between timed up-and-go and memory, executive function, and processing speed. J Am Geriatr Soc (2012) 1.14

The pattern of cognitive performance in CADASIL: a monogenic condition leading to subcortical ischemic vascular dementia. Am J Psychiatry (2005) 1.13

Autonomic function is impaired in elderly stroke survivors. Stroke (2005) 1.13

Photoreceptor coupling is controlled by connexin 35 phosphorylation in zebrafish retina. J Neurosci (2009) 1.11

Medial temporal atrophy rather than white matter hyperintensities predict cognitive decline in stroke survivors. Neurobiol Aging (2006) 1.11