The solution structure of the N-terminal domain of human vitronectin: proximal sites that regulate fibrinolysis and cell migration.

PubWeight™: 0.88‹?›

🔗 View Article (PMID 15123712)

Published in J Biol Chem on April 30, 2004

Authors

Anand Mayasundari1, Neil A Whittemore, Engin H Serpersu, Cynthia B Peterson

Author Affiliations

1: Department of Biochemistry and Cellular and Molecular Biology and the Center of Excellence in Structural Biology, University of Tennessee, Knoxville, Tennessee 37996, USA.

Articles by these authors

Studying multiprotein complexes by multisignal sedimentation velocity analytical ultracentrifugation. Proc Natl Acad Sci U S A (2004) 2.74

Hydrogen-deuterium (H/D) exchange mapping of Abeta 1-40 amyloid fibril secondary structure using nuclear magnetic resonance spectroscopy. Biochemistry (2005) 1.46

Slow amyloid nucleation via α-helix-rich oligomeric intermediates in short polyglutamine-containing huntingtin fragments. J Mol Biol (2011) 1.17

Discovery of non-carbohydrate inhibitors of aminoglycoside-modifying enzymes. Bioorg Med Chem (2005) 0.96

A mechanism for assembly of complexes of vitronectin and plasminogen activator inhibitor-1 from sedimentation velocity analysis. J Biol Chem (2005) 0.94

Incorporation of vitronectin into fibrin clots. Evidence for a binding interaction between vitronectin and gamma A/gamma' fibrinogen. J Biol Chem (2001) 0.94

A deletion mutant of vitronectin lacking the somatomedin B domain exhibits residual plasminogen activator inhibitor-1-binding activity. J Biol Chem (2008) 0.93

Solution structure of recombinant somatomedin B domain from vitronectin produced in Pichia pastoris. Protein Sci (2007) 0.91

A model for the three-dimensional structure of human plasma vitronectin from small-angle scattering measurements. Biochemistry (2005) 0.90

Characterization of a site on PAI-1 that binds to vitronectin outside of the somatomedin B domain. J Biol Chem (2008) 0.89

Vitronectin inhibits neutrophil apoptosis through activation of integrin-associated signaling pathways. Am J Respir Cell Mol Biol (2012) 0.88

Inhibition of neutrophil apoptosis by PAI-1. Am J Physiol Lung Cell Mol Physiol (2011) 0.87

Plasminogen activator inhibitor type 1 promotes the self-association of vitronectin into complexes exhibiting altered incorporation into the extracellular matrix. J Biol Chem (2002) 0.86

Detection of specific solvent rearrangement regions of an enzyme: NMR and ITC studies with aminoglycoside phosphotransferase(3')-IIIa. Biochemistry (2007) 0.85

Sml1p is a dimer in solution: characterization of denaturation and renaturation of recombinant Sml1p. Biochemistry (2004) 0.85

Crystal structure of plasminogen activator inhibitor-1 in an active conformation with normal thermodynamic stability. J Biol Chem (2011) 0.84

Metals affect the structure and activity of human plasminogen activator inhibitor-1. I. Modulation of stability and protease inhibition. Protein Sci (2011) 0.84

Activation of the zymogen to urokinase-type plasminogen activator is associated with increased interdomain flexibility. J Mol Biol (2011) 0.83

ATP binding enables broad antibiotic selectivity of aminoglycoside phosphotransferase(3')-IIIa: an elastic network analysis. J Mol Biol (2011) 0.83

Isolation of aminoglycoside nucleotidyltransferase (2'')-Ia from inclusion bodies as active, monomeric enzyme. Protein Expr Purif (2004) 0.83

Thermodynamics of aminoglycoside binding to aminoglycoside-3'-phosphotransferase IIIa studied by isothermal titration calorimetry. Biochemistry (2004) 0.83

Tissue-type plasminogen activator-plasmin-BDNF modulate glutamate-induced phase-shifts of the mouse suprachiasmatic circadian clock in vitro. Eur J Neurosci (2009) 0.83

Metals affect the structure and activity of human plasminogen activator inhibitor-1. II. Binding affinity and conformational changes. Protein Sci (2011) 0.83

Enzyme-substrate interactions with an antibiotic resistance enzyme: aminoglycoside nucleotidyltransferase(2'')-Ia characterized by kinetic and thermodynamic methods. Biochemistry (2005) 0.82

Interactions of coenzyme A with the aminoglycoside acetyltransferase (3)-IIIb and thermodynamics of a ternary system. Biochemistry (2010) 0.82

Antibiotic selection by the promiscuous aminoglycoside acetyltransferase-(3)-IIIb is thermodynamically achieved through the control of solvent rearrangement. Biochemistry (2011) 0.81

Vitronectin inhibits efferocytosis through interactions with apoptotic cells as well as with macrophages. J Immunol (2013) 0.81

Molecular determinants of affinity for aminoglycoside binding to the aminoglycoside nucleotidyltransferase(2'')-Ia. Biochemistry (2006) 0.80

Interactions of plasminogen activator inhibitor-1 with vitronectin involve an extensive binding surface and induce mutual conformational rearrangements. Biochemistry (2009) 0.80

Deciphering interactions of the aminoglycoside phosphotransferase(3')-IIIa with its ligands. Biopolymers (2009) 0.79

Assignment of the four disulfides in the N-terminal somatomedin B domain of native vitronectin isolated from human plasma. J Biol Chem (2004) 0.79

Metallohistins: a new class of plant metal-binding proteins. J Protein Chem (2002) 0.79

Coenzyme A binding to the aminoglycoside acetyltransferase (3)-IIIb increases conformational sampling of antibiotic binding site. Biochemistry (2011) 0.79

Ligand promiscuity through the eyes of the aminoglycoside N3 acetyltransferase IIa. Protein Sci (2013) 0.79

NMR detected hydrogen-deuterium exchange reveals differential dynamics of antibiotic- and nucleotide-bound aminoglycoside phosphotransferase 3'-IIIa. J Am Chem Soc (2009) 0.79

Thermodynamics and kinetics of association of antibiotics with the aminoglycoside acetyltransferase (3)-IIIb, a resistance-causing enzyme. Biochemistry (2010) 0.78

Cloning, overexpression, and purification of aminoglycoside antibiotic 3-acetyltransferase-IIIb: conformational studies with bound substrates. Biochemistry (2002) 0.78

Dissection of aminoglycoside-enzyme interactions: a calorimetric and NMR study of neomycin B binding to the aminoglycoside phosphotransferase(3')-IIIa. J Am Chem Soc (2006) 0.78

Thermodynamic characterization of a thermostable antibiotic resistance enzyme, the aminoglycoside nucleotidyltransferase (4'). Biochemistry (2012) 0.78

Transient kinetics of aminoglycoside phosphotransferase(3')-IIIa reveals a potential drug target in the antibiotic resistance mechanism. FEBS Lett (2012) 0.78

Protein dynamics are influenced by the order of ligand binding to an antibiotic resistance enzyme. Biochemistry (2013) 0.75

Thermophilic Enzyme or Mesophilic Enzyme with Enhanced Thermostability: Can We Draw a Line? J Phys Chem B (2017) 0.75

Correction to Thermodynamic Characterization of a Thermostable Antibiotic Resistance Enzyme, the Aminoglycoside Nucleotidyltransferase (4'). Biochemistry (2015) 0.75

Solvent reorganization plays a temperature-dependent role in antibiotic selection by a thermostable aminoglycoside nucleotidyltransferase-4'. Biochemistry (2014) 0.75