1
|
Phosphoinositide signalling links O-GlcNAc transferase to insulin resistance.
|
Nature
|
2008
|
3.98
|
2
|
Recruitment of O-GlcNAc transferase to promoters by corepressor mSin3A: coupling protein O-GlcNAcylation to transcriptional repression.
|
Cell
|
2002
|
2.89
|
3
|
O-GlcNAc modification is an endogenous inhibitor of the proteasome.
|
Cell
|
2003
|
2.51
|
4
|
Induction of KLF4 in basal keratinocytes blocks the proliferation-differentiation switch and initiates squamous epithelial dysplasia.
|
Oncogene
|
2005
|
2.50
|
5
|
Proteasome function is regulated by cyclic AMP-dependent protein kinase through phosphorylation of Rpt6.
|
J Biol Chem
|
2007
|
1.66
|
6
|
Characterization of the histone acetyltransferase (HAT) domain of a bifunctional protein with activable O-GlcNAcase and HAT activities.
|
J Biol Chem
|
2004
|
1.66
|
7
|
Keratin 14 Cre transgenic mice authenticate keratin 14 as an oocyte-expressed protein.
|
Genesis
|
2004
|
1.48
|
8
|
Disrupting the enzyme complex regulating O-GlcNAcylation blocks signaling and development.
|
Glycobiology
|
2006
|
1.41
|
9
|
Accumulation of protein O-GlcNAc modification inhibits proteasomes in the brain and coincides with neuronal apoptosis in brain areas with high O-GlcNAc metabolism.
|
J Neurochem
|
2004
|
1.20
|
10
|
Alloxan is an inhibitor of the enzyme O-linked N-acetylglucosamine transferase.
|
Biochem Biophys Res Commun
|
2002
|
1.14
|
11
|
Metabolic control of proteasome function.
|
Physiology (Bethesda)
|
2007
|
1.00
|
12
|
O-GlcNAc integrates the proteasome and transcriptome to regulate nuclear hormone receptors.
|
Mol Cell Biol
|
2006
|
0.99
|
13
|
The role of O-linked protein glycosylation in beta-cell dysfunction.
|
Int J Mol Med
|
2002
|
0.94
|
14
|
Phosphorylation of mouse glutamine-fructose-6-phosphate amidotransferase 2 (GFAT2) by cAMP-dependent protein kinase increases the enzyme activity.
|
J Biol Chem
|
2004
|
0.85
|
15
|
Location and characterization of the O-GlcNAcase active site.
|
Biochim Biophys Acta
|
2006
|
0.85
|
16
|
Streptozotocin, an O-GlcNAcase inhibitor, blunts insulin and growth hormone secretion.
|
Mol Cell Endocrinol
|
2002
|
0.84
|
17
|
The histone acetyltransferase NCOAT contains a zinc finger-like motif involved in substrate recognition.
|
J Biol Chem
|
2005
|
0.83
|
18
|
O-GlcNAcylation enhances FOXO4 transcriptional regulation in response to stress.
|
FEBS Lett
|
2010
|
0.82
|
19
|
Streptozotocin inhibits O-GlcNAcase via the production of a transition state analog.
|
Biochem Biophys Res Commun
|
2005
|
0.82
|
20
|
Increased O-GlcNAc causes disrupted lens fiber cell differentiation and cataracts.
|
Biochem Biophys Res Commun
|
2009
|
0.81
|
21
|
Muscle-specific overexpression of NCOATGK, splice variant of O-GlcNAcase, induces skeletal muscle atrophy.
|
Am J Physiol Cell Physiol
|
2010
|
0.77
|
22
|
Proteolytic processing of TGFalpha redirects its mitogenic activity: the membrane-anchored form is autocrine, the secreted form is paracrine.
|
Biochim Biophys Acta
|
2004
|
0.75
|