Safety and pharmacokinetics of escalated doses of weekly intravenous infusion of CCI-779, a novel mTOR inhibitor, in patients with cancer.

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Published in J Clin Oncol on May 10, 2004

Authors

Eric Raymond1, Jérôme Alexandre, Sandrine Faivre, Karina Vera, Eric Materman, Joseph Boni, Cathie Leister, Joan Korth-Bradley, Axel Hanauske, Jean-Pierre Armand

Author Affiliations

1: Department of Medicine, Gustave Roussy Institute, Vellefaux, France. eric.raymond@sls.ap-hop-paris.fr

Associated clinical trials:

Phase I Study of Docetaxel and Temsirolimus in Resistant Solid Malignancies | NCT00703625

Erlotinib and Temsirolimus for Solid Tumors | NCT00770263

A Phase II Study of EVEROLIMUS in Patients With Primary or Relapsed Chondrosarcomas (CHONRAD) | NCT02008019

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