Controlling tumor growth by modulating endogenous production of reactive oxygen species.

PubWeight™: 3.12‹?› | Rank: Top 1%

🔗 View Article (PMID 15705895)

Published in Cancer Res on February 01, 2005

Authors

Alexis Laurent1, Carole Nicco, Christiane Chéreau, Claire Goulvestre, Jérôme Alexandre, Arnaud Alves, Eva Lévy, Francois Goldwasser, Yves Panis, Olivier Soubrane, Bernard Weill, Frédéric Batteux

Author Affiliations

1: Laboratoire d'Immunologie and Laboratoire de Recherche Chirurgicale, Unité Propre de Recherche de l'Enseignement Supérieur 1833, Faculté Cochin, Université Paris V, 75679 Paris Cedex 14, France.

Articles citing this

(truncated to the top 100)

Autophagic programmed cell death by selective catalase degradation. Proc Natl Acad Sci U S A (2006) 4.81

Mechanisms of pre-apoptotic calreticulin exposure in immunogenic cell death. EMBO J (2009) 2.72

Redox-directed cancer therapeutics: molecular mechanisms and opportunities. Antioxid Redox Signal (2009) 2.33

Regulation of reactive oxygen species generation in cell signaling. Mol Cells (2011) 1.85

Redox control of the cell cycle in health and disease. Antioxid Redox Signal (2009) 1.72

Synergistic activity of the SRC family kinase inhibitor dasatinib and oxaliplatin in colon carcinoma cells is mediated by oxidative stress. Cancer Res (2009) 1.54

Regulation of lung cancer cell migration and invasion by reactive oxygen species and caveolin-1. J Biol Chem (2010) 1.43

Targeting cancer cells with reactive oxygen and nitrogen species generated by atmospheric-pressure air plasma. PLoS One (2014) 1.42

The involvement of the tyrosine kinase c-Src in the regulation of reactive oxygen species generation mediated by NADPH oxidase-1. Mol Biol Cell (2008) 1.37

A role for mitochondrial dysfunction in perpetuating radiation-induced genomic instability. Cancer Res (2006) 1.34

Anticancer activity of metal complexes: involvement of redox processes. Antioxid Redox Signal (2011) 1.32

Reactive oxygen species regulate hypoxia-inducible factor 1alpha differentially in cancer and ischemia. Mol Cell Biol (2008) 1.21

Gemcitabine/cannabinoid combination triggers autophagy in pancreatic cancer cells through a ROS-mediated mechanism. Cell Death Dis (2011) 1.18

Reactive oxygen species controls endometriosis progression. Am J Pathol (2009) 1.18

NQO1-activated phenothiazinium redox cyclers for the targeted bioreductive induction of cancer cell apoptosis. Free Radic Biol Med (2007) 1.16

Oxidative stress modulates DNA methylation during melanocyte anchorage blockade associated with malignant transformation. Neoplasia (2007) 1.15

Redox control of liver function in health and disease. Antioxid Redox Signal (2010) 1.12

Production of superoxide anions by keratinocytes initiates P. acnes-induced inflammation of the skin. PLoS Pathog (2009) 1.11

Phase 2 study of neoadjuvant treatment with NOV-002 in combination with doxorubicin and cyclophosphamide followed by docetaxel in patients with HER-2 negative clinical stage II-IIIc breast cancer. Breast Cancer Res Treat (2011) 1.08

Role and cellular source of nicotinamide adenine dinucleotide phosphate oxidase in hepatic fibrosis. Hepatology (2010) 1.08

Downregulation of tumor growth and invasion by redox-active nanoparticles. Antioxid Redox Signal (2013) 1.07

Cytotoxicity of withaferin A in glioblastomas involves induction of an oxidative stress-mediated heat shock response while altering Akt/mTOR and MAPK signaling pathways. Invest New Drugs (2012) 1.06

Modulation of cellular redox state underlies antagonism between oxaliplatin and cetuximab in human colorectal cancer cell lines. Br J Pharmacol (2009) 1.05

Reactive oxygen species signaling in cancer: comparison with aging. Aging Dis (2010) 1.02

ROS-activated anticancer prodrugs: a new strategy for tumor-specific damage. Ther Deliv (2012) 1.02

Hyperbaric oxygen therapy for malignancy: a review. World J Surg (2006) 1.01

NADPH oxidase NOX1 controls autocrine growth of liver tumor cells through up-regulation of the epidermal growth factor receptor pathway. J Biol Chem (2010) 1.00

Mcl-1 promotes lung cancer cell migration by directly interacting with VDAC to increase mitochondrial Ca2+ uptake and reactive oxygen species generation. Cell Death Dis (2014) 0.98

Cancer prevention and therapy through the modulation of the tumor microenvironment. Semin Cancer Biol (2015) 0.97

Radical oxygen species production induced by advanced oxidation protein products predicts clinical evolution and response to treatment in systemic sclerosis. Ann Rheum Dis (2007) 0.95

Sildenafil inhibits the growth of human colorectal cancer in vitro and in vivo. Am J Cancer Res (2015) 0.94

Replicative senescence induced by Romo1-derived reactive oxygen species. J Biol Chem (2008) 0.93

Liver injury induced by anticancer chemotherapy and radiation therapy. Int J Hepatol (2013) 0.93

SOD mimetics: a novel class of androgen receptor inhibitors that suppresses castration-resistant growth of prostate cancer. Mol Cancer Ther (2011) 0.92

The mTOR/AKT inhibitor temsirolimus prevents deep infiltrating endometriosis in mice. Am J Pathol (2011) 0.91

The redox antimalarial dihydroartemisinin targets human metastatic melanoma cells but not primary melanocytes with induction of NOXA-dependent apoptosis. Invest New Drugs (2011) 0.91

Synthesis and screening of 3-MA derivatives for autophagy inhibitors. Autophagy (2013) 0.91

Antimelanoma activity of the redox dye DCPIP (2,6-dichlorophenolindophenol) is antagonized by NQO1. Biochem Pharmacol (2009) 0.91

Hepatitis B virus X protein enhances cisplatin-induced hepatotoxicity via a mechanism involving degradation of Mcl-1. J Virol (2011) 0.91

The catalase C-262T gene polymorphism and cancer risk: a systematic review and meta-analysis. Medicine (Baltimore) (2015) 0.90

Treatment of oxaliplatin-induced peripheral neuropathy by intravenous mangafodipir. J Clin Invest (2013) 0.90

Manganese superoxide dismutase regulates a redox cycle within the cell cycle. Antioxid Redox Signal (2013) 0.90

The impact of redox and thiol status on the bone marrow: Pharmacological intervention strategies. Pharmacol Ther (2010) 0.90

Base excision repair of reactive oxygen species-initiated 7,8-dihydro-8-oxo-2'-deoxyguanosine inhibits the cytotoxicity of platinum anticancer drugs. Mol Cancer Ther (2009) 0.89

Oxidative stress induces mitochondrial DNA damage and cytotoxicity through independent mechanisms in human cancer cells. Biomed Res Int (2012) 0.89

Enhanced tumorigenicity by mitochondrial DNA mild mutations. Oncotarget (2015) 0.89

Thiostrepton is an inducer of oxidative and proteotoxic stress that impairs viability of human melanoma cells but not primary melanocytes. Biochem Pharmacol (2012) 0.88

C-reactive protein, lipid-soluble micronutrients, and survival in colorectal cancer patients. Cancer Epidemiol Biomarkers Prev (2013) 0.88

Oxidative inactivation of the lipid phosphatase phosphatase and tensin homolog on chromosome ten (PTEN) as a novel mechanism of acquired long QT syndrome. J Biol Chem (2010) 0.86

Phosphorylation and subcellular localization of p27Kip1 regulated by hydrogen peroxide modulation in cancer cells. PLoS One (2012) 0.86

Quantifying intracellular hydrogen peroxide perturbations in terms of concentration. Redox Biol (2014) 0.85

The pepper's natural ingredient capsaicin induces autophagy blockage in prostate cancer cells. Oncotarget (2016) 0.85

Oxidative cytotoxic agent withaferin A resensitizes temozolomide-resistant glioblastomas via MGMT depletion and induces apoptosis through Akt/mTOR pathway inhibitory modulation. Invest New Drugs (2014) 0.85

Cellular Mechanisms of Oxidative Stress and Action in Melanoma. Oxid Med Cell Longev (2015) 0.84

Ent-11α-Hydroxy-15-oxo-kaur-16-en-19-oic-acid Inhibits Growth of Human Lung Cancer A549 Cells by Arresting Cell Cycle and Triggering Apoptosis. Chin J Cancer Res (2012) 0.84

Role of Reactive Oxygen Species in the Abrogation of Oxaliplatin Activity by Cetuximab in Colorectal Cancer. J Natl Cancer Inst (2015) 0.84

Reactive oxygen species-mediated therapeutic response and resistance in glioblastoma. Cell Death Dis (2015) 0.83

Involvement of tumor macrophage HIFs in chemotherapy effectiveness: mathematical modeling of oxygen, pH, and glutathione. PLoS One (2014) 0.82

Increased serum oxidative stress markers in women with uterine leiomyoma. PLoS One (2013) 0.82

Distinct redox profiles of selected human prostate carcinoma cell lines: implications for rational design of redox therapy. Cancers (Basel) (2011) 0.82

Mechanisms of superoxide signaling in epigenetic processes: relation to aging and cancer. Aging Dis (2015) 0.82

Chemical genetics analysis of an aniline mustard anticancer agent reveals complex I of the electron transport chain as a target. J Biol Chem (2011) 0.81

Highly and Broad-Spectrum In Vitro Antitumor Active cis-Dichloridoplatinum(II) Complexes with 7-Azaindoles. PLoS One (2015) 0.81

The magnetic resonance imaging contrast agent mangafodipir exerts antitumor activity via a previously described superoxide dismutase mimetic activity. Cancer Res (2006) 0.81

Mitochondrial genome variations in advanced stage endometriosis: a study in South Indian population. PLoS One (2012) 0.81

Mammalian numb-interacting protein 1/dual oxidase maturation factor 1 directs neuronal fate in stem cells. J Biol Chem (2010) 0.81

Suppression of cancer growth by nonviral gene therapy based on a novel reactive oxygen species-responsive promoter. Mol Ther (2009) 0.81

3-Methyl pyruvate enhances radiosensitivity through increasing mitochondria-derived reactive oxygen species in tumor cell lines. J Radiat Res (2014) 0.81

The effect of alpha lipoic acid on the developmental competence of mouse isolated preantral follicles. J Assist Reprod Genet (2012) 0.80

Spontaneous and radiation-induced chromosomal instability and persistence of chromosome aberrations after radiotherapy in lymphocytes from prostate cancer patients. Radiat Environ Biophys (2009) 0.80

Select cyclopentenone prostaglandins trigger glutathione efflux and the role of ABCG2 transport. Free Radic Biol Med (2009) 0.79

The Antitumor Activity of Plant-Derived Non-Psychoactive Cannabinoids. J Neuroimmune Pharmacol (2015) 0.79

The organotelluride catalyst LAB027 prevents colon cancer growth in the mice. Cell Death Dis (2011) 0.79

First clinical experience with the magnetic resonance imaging contrast agent and superoxide dismutase mimetic mangafodipir as an adjunct in cancer chemotherapy-a translational study. Transl Oncol (2012) 0.79

Malabaricone-A induces a redox imbalance that mediates apoptosis in U937 cell line. PLoS One (2012) 0.79

Effects of MnDPDP and ICRF-187 on Doxorubicin-Induced Cardiotoxicity and Anticancer Activity. Transl Oncol (2012) 0.78

Oxaliplatin induces different cellular and molecular chemoresistance patterns in colorectal cancer cell lines of identical origins. BMC Genomics (2013) 0.78

Ubiquitin C-terminal hydrolase-L1 increases cancer cell invasion by modulating hydrogen peroxide generated via NADPH oxidase 4. Oncotarget (2015) 0.78

Effects of methanolic extracts from broad beans on cellular growth and antioxidant enzyme activity. Environ Health Prev Med (2007) 0.78

Efficient antitumor effect of co-drug-loaded nanoparticles with gelatin hydrogel by local implantation. Sci Rep (2016) 0.78

European contribution to the study of ROS: A summary of the findings and prospects for the future from the COST action BM1203 (EU-ROS). Redox Biol (2017) 0.77

Oxidative damage and antioxidative therapy in systemic sclerosis. Mediators Inflamm (2014) 0.77

Targeting reactive oxygen species in development and progression of pancreatic cancer. Expert Rev Anticancer Ther (2016) 0.77

Dasatinib, a Src inhibitor, sensitizes liver metastatic colorectal carcinoma to oxaliplatin in tumors with high levels of phospho-Src. Oncotarget (2016) 0.77

Effect of Uncaria tomentosa Extract on Apoptosis Triggered by Oxaliplatin Exposure on HT29 Cells. Evid Based Complement Alternat Med (2014) 0.77

ROS and Brain Gliomas: An Overview of Potential and Innovative Therapeutic Strategies. Int J Mol Sci (2016) 0.77

Superior therapeutic index of calmangafodipir in comparison to mangafodipir as a chemotherapy adjunct. Transl Oncol (2012) 0.76

Pro-Oxidant Activity of Amine-Pyridine-Based Iron Complexes Efficiently Kills Cancer and Cancer Stem-Like Cells. PLoS One (2015) 0.76

Imbalance in redox status is associated with tumor aggressiveness and poor outcome in lung adenocarcinoma patients. J Cancer Res Clin Oncol (2014) 0.76

Systemic oxidative stress could predict assisted reproductive technique outcome. J Assist Reprod Genet (2015) 0.76

Prostate tumor-induced angiogenesis is blocked by exosomes derived from menstrual stem cells through the inhibition of reactive oxygen species. Oncotarget (2016) 0.76

Piperlongumine Suppresses Proliferation of Human Oral Squamous Cell Carcinoma through Cell Cycle Arrest, Apoptosis and Senescence. Int J Mol Sci (2016) 0.76

Antiproliferative effects of cannabinoid agonists on deep infiltrating endometriosis. Am J Pathol (2010) 0.76

Tumor grade related expression of neuroglobin is negatively regulated by PPARγ and confers antioxidant activity in glioma progression. Redox Biol (2017) 0.75

The Role of Catalase C262T Gene Polymorphism in the Susceptibility and Survival of Cancers. Sci Rep (2016) 0.75

Magnetic Resonance Imaging Identifies Differential Response to Pro-Oxidant Chemotherapy in a Xenograft Model. Transl Oncol (2016) 0.75

SH003 induces apoptosis of DU145 prostate cancer cells by inhibiting ERK-involved pathway. BMC Complement Altern Med (2016) 0.75

Yu Ping Feng San reverses cisplatin-induced multi-drug resistance in lung cancer cells via regulating drug transporters and p62/TRAF6 signalling. Sci Rep (2016) 0.75

Co-delivery of paclitaxel and tetrandrine via iRGD peptide conjugated lipid-polymer hybrid nanoparticles overcome multidrug resistance in cancer cells. Sci Rep (2017) 0.75

Artonin E induces p53-independent G1 cell cycle arrest and apoptosis through ROS-mediated mitochondrial pathway and livin suppression in MCF-7 cells. Drug Des Devel Ther (2017) 0.75

Articles by these authors

Randomized, double-blind study of denosumab versus zoledronic acid in the treatment of bone metastases in patients with advanced cancer (excluding breast and prostate cancer) or multiple myeloma. J Clin Oncol (2011) 6.16

Amoxicillin plus clavulanic acid versus appendicectomy for treatment of acute uncomplicated appendicitis: an open-label, non-inferiority, randomised controlled trial. Lancet (2011) 5.89

Methodological index for non-randomized studies (minors): development and validation of a new instrument. ANZ J Surg (2003) 5.61

Antimicrobial activity of mucosal-associated invariant T cells. Nat Immunol (2010) 4.25

Safety and pharmacokinetics of escalated doses of weekly intravenous infusion of CCI-779, a novel mTOR inhibitor, in patients with cancer. J Clin Oncol (2004) 3.40

Cholecystocolonic fistula: facts and myths. A review of the 231 published cases. J Hepatobiliary Pancreat Surg (2008) 2.40

Postoperative mortality and morbidity in French patients undergoing colorectal surgery: results of a prospective multicenter study. Arch Surg (2005) 2.39

Recommendations for laparoscopic liver resection: a report from the second international consensus conference held in Morioka. Ann Surg (2015) 2.36

ICAM-1 on exosomes from mature dendritic cells is critical for efficient naive T-cell priming. Blood (2005) 2.34

Pancreaticogastrostomy is superior to pancreaticojejunostomy for prevention of pancreatic fistula after pancreaticoduodenectomy: an updated meta-analysis of randomized controlled trials. Ann Surg (2015) 2.29

Benefit of laparoscopy for rectal resection in patients operated simultaneously for synchronous liver metastases: preliminary experience. Surgery (2008) 2.25

Brief report: prevalence of antineutrophil cytoplasmic antibodies in infective endocarditis. Arthritis Rheumatol (2014) 2.24

Improvement of the therapeutic index of anticancer drugs by the superoxide dismutase mimic mangafodipir. J Natl Cancer Inst (2006) 2.18

Laparoscopic living donor hepatectomy for liver transplantation in children. Lancet (2002) 2.15

Perineal or Abdominal Approach First During Intersphincteric Resection for Low Rectal Cancer: Which Is the Best Strategy? Dis Colon Rectum (2015) 2.13

Segmental reversal of the small bowel can end permanent parenteral nutrition dependency: an experience of 38 adults with short bowel syndrome. Ann Surg (2012) 2.01

Liver transplantation for neuroendocrine tumors in Europe-results and trends in patient selection: a 213-case European liver transplant registry study. Ann Surg (2013) 1.98

Factors associated with clinically significant anastomotic leakage after large bowel resection: multivariate analysis of 707 patients. World J Surg (2002) 1.97

Platelet CD154 potentiates interferon-alpha secretion by plasmacytoid dendritic cells in systemic lupus erythematosus. Sci Transl Med (2010) 1.83

Laparoscopic colorectal surgery in elderly patients: a matched case-control study in 178 patients. J Am Coll Surg (2007) 1.73

Early survival and safety of ALPPS: first report of the International ALPPS Registry. Ann Surg (2014) 1.69

Mangafodipir prevents liver injury induced by acetaminophen in the mouse. J Hepatol (2003) 1.67

Rectal cancer surgery with or without bowel preparation: The French GRECCAR III multicenter single-blinded randomized trial. Ann Surg (2010) 1.67

Accumulation of hydrogen peroxide is an early and crucial step for paclitaxel-induced cancer cell death both in vitro and in vivo. Int J Cancer (2006) 1.60

Treatment of stage IVA hepatocellular carcinoma: should we reappraise the role of surgery? Arch Surg (2008) 1.58

Redo surgery for failed colorectal or coloanal anastomosis: a valuable surgical challenge. Surgery (2010) 1.56

Cost effectiveness of integrated medicine in patients with cancer receiving anticancer chemotherapy. J Oncol Pract (2012) 1.50

Erythromycin improves the quality of EGD in patients with acute upper GI bleeding: a randomized controlled study. Gastrointest Endosc (2002) 1.49

Sinusoidal obstruction syndrome and nodular regenerative hyperplasia are frequent oxaliplatin-associated liver lesions and partially prevented by bevacizumab in patients with hepatic colorectal metastasis. Histopathology (2010) 1.48

Postresuscitation syndrome: potential role of hydroxyl radical-induced endothelial cell damage. Crit Care Med (2011) 1.47

Inhibition of maturation and function of dendritic cells by intravenous immunoglobulin. Blood (2002) 1.46

Removable intraductal stenting in duct-to-duct biliary reconstruction in liver transplantation. Transpl Int (2011) 1.42

Preliminary report of major surgery in liver transplant recipients receiving m-TOR inhibitors without therapeutic discontinuation. World J Surg (2014) 1.42

Split liver transplantation using extended right grafts: the natural history of segment 4 and its impact on early postoperative outcomes. Liver Transpl (2012) 1.40

[Ileoanal anastomosis without ileostomy... and without laparotomy?]. Gastroenterol Clin Biol (2002) 1.38

Patients with acute liver failure listed for superurgent liver transplantation in France: reevaluation of the Clichy-Villejuif criteria. Liver Transpl (2015) 1.38

European experience of laparoscopic major hepatectomy. J Hepatobiliary Pancreat Sci (2013) 1.33

International experience for laparoscopic major liver resection. J Hepatobiliary Pancreat Sci (2014) 1.23

Risk factors for intra-abdominal septic complications after a first ileocecal resection for Crohn's disease: a multivariate analysis in 161 consecutive patients. Dis Colon Rectum (2007) 1.22

Pivotal role of superoxide anion and beneficial effect of antioxidant molecules in murine steatohepatitis. Hepatology (2004) 1.21

Reactive oxygen species controls endometriosis progression. Am J Pathol (2009) 1.18

Mitogenic insulin receptor-A is overexpressed in human hepatocellular carcinoma due to EGFR-mediated dysregulation of RNA splicing factors. Cancer Res (2013) 1.17

Sorafenib-induced hepatocellular carcinoma cell death depends on reactive oxygen species production in vitro and in vivo. Mol Cancer Ther (2012) 1.13

Recurrent liver abscess secondary to ingested fish bone migration: report of a case. Surg Today (2008) 1.13

Predicting postoperative mortality in patients undergoing colorectal surgery. World J Surg (2006) 1.11

Production of superoxide anions by keratinocytes initiates P. acnes-induced inflammation of the skin. PLoS Pathog (2009) 1.11

Which magnetic resonance imaging findings accurately evaluate inflammation in small bowel Crohn's disease? A retrospective comparison with surgical pathologic analysis. Inflamm Bowel Dis (2010) 1.10

Impact of complex Crohn's disease on the outcome of laparoscopic ileocecal resection: a comparative clinical study in 124 patients. Dis Colon Rectum (2009) 1.10

Effect of integrated palliative care on the quality of end-of-life care: retrospective analysis of 521 cancer patients. BMJ Support Palliat Care (2012) 1.09

Altered endoplasmic reticulum stress affects translation in inactive colon tissue from patients with ulcerative colitis. Gastroenterology (2011) 1.09

Expression of endomembrane calcium pumps in colon and gastric cancer cells. Induction of SERCA3 expression during differentiation. J Biol Chem (2002) 1.09

An observational study of bevacizumab-induced hypertension as a clinical biomarker of antitumor activity. Oncologist (2011) 1.08

Selective oxidation of DNA topoisomerase 1 induces systemic sclerosis in the mouse. J Immunol (2009) 1.08

AGEs bind to mesothelial cells via RAGE and stimulate VCAM-1 expression. Kidney Int (2002) 1.05

Targeting ADAM-17/notch signaling abrogates the development of systemic sclerosis in a murine model. Arthritis Rheum (2010) 1.05

Major liver resection without clamping: a prospective reappraisal in the era of modern surgical tools. J Am Coll Surg (2004) 1.04

Involvement of Ca2+/calmodulin-dependent protein kinase II in endothelial NO production and endothelium-dependent relaxation. Am J Physiol Heart Circ Physiol (2003) 1.04

The AFC score: validation of a 4-item predicting score of postoperative mortality after colorectal resection for cancer or diverticulitis: results of a prospective multicenter study in 1049 patients. Ann Surg (2007) 1.04

Temporary placement of partially covered self-expandable metal stents for anastomotic biliary strictures after liver transplantation: a prospective, multicenter study. Gastrointest Endosc (2010) 1.04

Multiple OXPHOS deficiency in the liver, kidney, heart, and skeletal muscle of patients with methylmalonic aciduria and propionic aciduria. Pediatr Res (2009) 1.04

HIP/PAP accelerates liver regeneration and protects against acetaminophen injury in mice. Hepatology (2005) 1.03