Published in BMC Genomics on May 23, 2004
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Beta cell-specific Znt8 deletion in mice causes marked defects in insulin processing, crystallisation and secretion. Diabetologia (2010) 3.48
Insulin storage and glucose homeostasis in mice null for the granule zinc transporter ZnT8 and studies of the type 2 diabetes-associated variants. Diabetes (2009) 2.92
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X-ray fluorescence microscopy reveals accumulation and secretion of discrete intracellular zinc pools in the lactating mouse mammary gland. PLoS One (2010) 1.09
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SLC30A3 responds to glucose- and zinc variations in beta-cells and is critical for insulin production and in vivo glucose-metabolism during beta-cell stress. PLoS One (2009) 0.99
The cation diffusion facilitator gene cdf-2 mediates zinc metabolism in Caenorhabditis elegans. Genetics (2009) 0.94
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A novel triple mix radiobinding assay for the three ZnT8 (ZnT8-RWQ) autoantibody variants in children with newly diagnosed diabetes. J Immunol Methods (2011) 0.93
Genetic factors and manganese-induced neurotoxicity. Front Genet (2014) 0.90
Effect of methylene blue on the genomic response to reperfusion injury induced by cardiac arrest and cardiopulmonary resuscitation in porcine brain. BMC Med Genomics (2010) 0.85
Identification of inositol polyphosphate 4-phosphatase type II as a novel tumor resistance biomarker in human laryngeal cancer HEp-2 cells. Cancer Biol Ther (2012) 0.83
Radioresistance in a human laryngeal squamous cell carcinoma cell line is associated with DNA methylation changes and topoisomerase II α. Cancer Biol Ther (2015) 0.82
Direct Comparison of Manganese Detoxification/Efflux Proteins and Molecular Characterization of ZnT10 Protein as a Manganese Transporter. J Biol Chem (2016) 0.81
Common Polymorphisms in the Solute Carrier SLC30A10 are Associated With Blood Manganese and Neurological Function. Toxicol Sci (2015) 0.80
Identification of CYP genes in Mytilus (mussel) and Crassostrea (oyster) species: first approach to the full complement of cytochrome P450 genes in bivalves. Mar Environ Res (2009) 0.80
Comparative genomic analysis of slc39a12/ZIP12: insight into a zinc transporter required for vertebrate nervous system development. PLoS One (2014) 0.80
Widespread expression of zinc transporter ZnT (SLC30) family members in mouse endocrine cells. Histochem Cell Biol (2012) 0.78
A potential role for zinc alterations in the pathogenesis of Alzheimer's disease. Biofactors (2012) 0.77
The effects of interactions between selenium and zinc serum concentration and SEP15 and SLC30A3 gene polymorphisms on memory scores in a population of mature and elderly adults. Genes Nutr (2013) 0.76
Genome wide identification, phylogeny and expression of zinc transporter genes in common carp. PLoS One (2014) 0.75
Disease-Homologous Mutation in the Cation Diffusion Facilitator Protein MamM Causes Single-Domain Structural Loss and Signifies Its Importance. Sci Rep (2016) 0.75
Zinc transporters are differentially expressed in human non-small cell lung cancer. Oncotarget (2016) 0.75
Upregulation of zinc transporter 2 in the blood-CSF barrier following lead exposure. Exp Biol Med (Maywood) (2013) 0.75
Influence of iron metabolism on manganese transport and toxicity. Metallomics (2017) 0.75
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Kinetic study of the antiport mechanism of an Escherichia coli zinc transporter, ZitB. J Biol Chem (2004) 1.40
ZnT7, a novel mammalian zinc transporter, accumulates zinc in the Golgi apparatus. J Biol Chem (2002) 1.37
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Functional characterization of a novel mammalian zinc transporter, ZnT6. J Biol Chem (2002) 1.35
Synaptically-released zinc inhibits N-methyl-D-aspartate receptor activation at recurrent mossy fiber synapses. Brain Res (2001) 1.16
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Differential regulation of zinc efflux transporters ZnT-1, ZnT-5 and ZnT-7 gene expression by zinc levels: a real-time RT-PCR study. Biochem Pharmacol (2004) 1.02
Distribution of the zinc transporter ZnT-1 in comparison with chelatable zinc in the mouse brain. J Comp Neurol (2002) 0.96
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Identification and cloning of a beta-cell-specific zinc transporter, ZnT-8, localized into insulin secretory granules. Diabetes (2004) 4.25
In vivo expression and functional characterization of the zinc transporter ZnT8 in glucose-induced insulin secretion. J Cell Sci (2006) 3.82
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Antioxidant supplementation increases the risk of skin cancers in women but not in men. J Nutr (2007) 2.66
Cyclobutane pyrimidine dimers are predominant DNA lesions in whole human skin exposed to UVA radiation. Proc Natl Acad Sci U S A (2006) 2.19
Effect of supplementation with antioxidants upon long-term risk of hypertension in the SU.VI.MAX study: association with plasma antioxidant levels. J Hypertens (2005) 1.67
Investigation of transport mechanisms and regulation of intracellular Zn2+ in pancreatic alpha-cells. J Biol Chem (2008) 1.48
Oxidation of the sugar moiety of DNA by ionizing radiation or bleomycin could induce the formation of a cluster DNA lesion. Proc Natl Acad Sci U S A (2007) 1.47
Enzymatic antioxidant balance and cognitive decline in aging--the EVA study. Eur J Epidemiol (2004) 1.45
Soil fungi reduce the iron content and the DNA damaging effects of asbestos fibers. Environ Sci Technol (2006) 1.40
Cellular background level of 8-oxo-7,8-dihydro-2'-deoxyguanosine: an isotope based method to evaluate artefactual oxidation of DNA during its extraction and subsequent work-up. Carcinogenesis (2002) 1.36
ZnT-8, a pancreatic beta-cell-specific zinc transporter. Biometals (2005) 1.32
Effects of long-term antioxidant supplementation and association of serum antioxidant concentrations with risk of metabolic syndrome in adults. Am J Clin Nutr (2009) 1.21
Expression of prion protein increases cellular copper binding and antioxidant enzyme activities but not copper delivery. J Biol Chem (2002) 1.15
Repair of the three main types of bipyrimidine DNA photoproducts in human keratinocytes exposed to UVB and UVA radiations. DNA Repair (Amst) (2005) 1.14
Characterization of lysine-guanine cross-links upon one-electron oxidation of a guanine-containing oligonucleotide in the presence of a trilysine peptide. J Am Chem Soc (2006) 1.11
Free zinc ions outside a narrow concentration range are toxic to a variety of cells in vitro. Exp Biol Med (Maywood) (2010) 1.10
Overloaded training increases exercise-induced oxidative stress and damage. Can J Appl Physiol (2003) 1.08
Tolbutamide controls glucagon release from mouse islets differently than glucose: involvement of K(ATP) channels from both α-cells and δ-cells. Diabetes (2013) 1.06
Evaluation of cytotoxicity and oxidative DNA damaging effects of di(2-ethylhexyl)-phthalate (DEHP) and mono(2-ethylhexyl)-phthalate (MEHP) on MA-10 Leydig cells and protection by selenium. Toxicol Appl Pharmacol (2010) 1.06
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Total plasma carotenoids and mortality in the elderly: results of the Epidemiology of Vascular Ageing (EVA) study. Br J Nutr (2008) 1.05
Predominance of the 1,N2-propano 2'-deoxyguanosine adduct among 4-hydroxy-2-nonenal-induced DNA lesions. Free Radic Biol Med (2004) 1.02
Differential regulation of zinc efflux transporters ZnT-1, ZnT-5 and ZnT-7 gene expression by zinc levels: a real-time RT-PCR study. Biochem Pharmacol (2004) 1.02
Cytotoxic effect of ciprofloxacin in primary culture of rat astrocytes and protection by Vitamin E. Toxicology (2006) 1.00
SLC30A8 mutations in type 2 diabetes. Diabetologia (2014) 0.99
Preventive effect of zinc against cadmium-induced oxidative stress in the rat testis. J Reprod Dev (2007) 0.99
Prion infection impairs copper binding of cultured cells. J Biol Chem (2003) 0.99
Hydroxyl radical is not the main reactive species involved in the degradation of DNA bases by copper in the presence of hydrogen peroxide. Chem Res Toxicol (2003) 0.98
Trapping of 4-hydroxynonenal by glutathione efficiently prevents formation of DNA adducts in human cells. Free Radic Biol Med (2007) 0.96
Plasma carotenoid levels and cognitive performance in an elderly population: results of the EVA Study. J Gerontol A Biol Sci Med Sci (2007) 0.96
TOX4 and its binding partners recognize DNA adducts generated by platinum anticancer drugs. Arch Biochem Biophys (2010) 0.94
Zinc transporter gene expression is regulated by pro-inflammatory cytokines: a potential role for zinc transporters in beta-cell apoptosis? BMC Endocr Disord (2009) 0.94
Larger yield of cyclobutane dimers than 8-oxo-7,8-dihydroguanine in the DNA of UVA-irradiated human skin cells. Mutat Res (2004) 0.94
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Assessment of DNA damage by comet assay on frozen total blood: method and evaluation in smokers and non-smokers. Mutat Res (2004) 0.93
Impairment of the antioxidant properties of serum albumin in patients with diabetes: protective effects of metformin. Clin Sci (Lond) (2008) 0.93
Effects of static magnetic field and cadmium on oxidative stress and DNA damage in rat cortex brain and hippocampus. Toxicol Ind Health (2010) 0.93
Selenium supplementation ameliorates static magnetic field-induced disorders in antioxidant status in rat tissues. Environ Toxicol Pharmacol (2010) 0.92
Antioxidant supplementation preserves antioxidant response in physical training and low antioxidant intake. Br J Nutr (2004) 0.92
Ciprofloxacin-induced DNA damage in primary culture of rat astrocytes and protection by Vitamin E. Neurotoxicology (2005) 0.92
Alterations of the lipid profile after 7.5 years of low-dose antioxidant supplementation in the SU.VI.MAX Study. Lipids (2005) 0.90
The toxicity redox mechanisms of cadmium alone or together with copper and zinc homeostasis alteration: its redox biomarkers. J Trace Elem Med Biol (2011) 0.89
Detection of chlorinated DNA and RNA nucleosides by HPLC coupled to tandem mass spectrometry as potential biomarkers of inflammation. J Chromatogr B Analyt Technol Biomed Life Sci (2005) 0.88
A robust liquid chromatography tandem mass spectrometry method for total plasma homocysteine determination in clinical practice. Clin Chem Lab Med (2006) 0.88
Homocysteine, cardiovascular disease risk factors, and habitual diet in the French Supplementation with Antioxidant Vitamins and Minerals Study. Am J Clin Nutr (2002) 0.88
Influence of static magnetic field on cadmium toxicity: study of oxidative stress and DNA damage in rat tissues. J Trace Elem Med Biol (2006) 0.88
Oxidative stress impairs intracellular events involved in antigen processing and presentation to T cells. Cell Stress Chaperones (2003) 0.88
Singlet oxygen-mediated damage to cellular DNA determined by the comet assay associated with DNA repair enzymes. Biol Chem (2004) 0.87
Antioxidant status and risk of cancer in the SU.VI.MAX study: is the effect of supplementation dependent on baseline levels? Br J Nutr (2005) 0.87
Protective effect of selenium supplementation on the genotoxicity of di(2-ethylhexyl)phthalate and mono(2-ethylhexyl)phthalate treatment in LNCaP cells. Free Radic Biol Med (2010) 0.87
Antioxidant supplementation and tapering exercise improve exercise-induced antioxidant response. J Am Coll Nutr (2003) 0.87
Plasma carotenoids and onset of dysglycemia in an elderly population: results of the Epidemiology of Vascular Ageing Study. Diabetes Care (2008) 0.87
Overexpression of cellular prion protein induces an antioxidant environment altering T cell development in the thymus. J Immunol (2006) 0.87
Oxidative stress induced by cadmium in the C6 cell line: role of copper and zinc. Biol Trace Elem Res (2011) 0.86
Incidence of cancers, ischemic cardiovascular diseases and mortality during 5-year follow-up after stopping antioxidant vitamins and minerals supplements: a postintervention follow-up in the SU.VI.MAX Study. Int J Cancer (2010) 0.86
Unrepaired cyclobutane pyrimidine dimers do not prevent proliferation of UV-B-irradiated cultured human fibroblasts. Photochem Photobiol (2004) 0.86
Iron status and risk of cancers in the SU.VI.MAX cohort. J Nutr (2005) 0.86
Detection of new radiation-induced DNA lesions by liquid chromatography coupled to tandem mass spectrometry. Rapid Commun Mass Spectrom (2004) 0.85
Changes in gene expression in rat thymocytes identified by cDNA array support the occurrence of oxidative stress in early magnesium deficiency. Biochim Biophys Acta (2002) 0.85
Differential repair of UVB-induced cyclobutane pyrimidine dimers in cultured human skin cells and whole human skin. DNA Repair (Amst) (2008) 0.84
Relationships between different types of fruit and vegetable consumption and serum concentrations of antioxidant vitamins. Br J Nutr (2008) 0.84
Ageing effects on the expression of cell defence genes after UVA irradiation in human male cutaneous fibroblasts using cDNA arrays. J Photochem Photobiol B (2005) 0.83
Differential p53-mediated responses to solar-simulated radiation in human papillomavirus type 16-infected keratinocytes. Exp Dermatol (2007) 0.82
Zinc supplementation ameliorates static magnetic field-induced oxidative stress in rat tissues. Environ Toxicol Pharmacol (2006) 0.82
Influence of a static magnetic field (250 mT) on the antioxidant response and DNA integrity in THP1 cells. Phys Med Biol (2007) 0.82
Effects of cadmium and zinc on solar-simulated light-irradiated cells: potential role of zinc-metallothionein in zinc-induced genoprotection. Arch Biochem Biophys (2002) 0.82
Biphasic response of ciprofloxacin in human fibroblast cell cultures. Nonlinearity Biol Toxicol Med (2003) 0.82
Hypoxia lowers SLC30A8/ZnT8 expression and free cytosolic Zn2+ in pancreatic beta cells. Diabetologia (2014) 0.82
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Thyroidal effects of di-(2-ethylhexyl) phthalate in rats of different selenium status. J Environ Pathol Toxicol Oncol (2012) 0.81
Age-dependent DNA repair and cell cycle distribution of human skin fibroblasts in response to UVA irradiation. J Photochem Photobiol B (2006) 0.81
Low doses of selenium specifically stimulate the repair of oxidative DNA damage in LNCaP prostate cancer cells. Free Radic Res (2012) 0.80
Relation between homocysteine concentrations and the consumption of different types of alcoholic beverages: the French Supplementation with Antioxidant Vitamins and Minerals Study. Am J Clin Nutr (2003) 0.80
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Iodine and/or selenium deficiency alters tissue distribution pattern of other trace elements in rats. Biol Trace Elem Res (2003) 0.79
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An oligonucleotide microarray for the monitoring of repair enzyme activity toward different DNA base damage. Anal Biochem (2004) 0.78
Interactions between doxorubicin and the human iron regulatory system. Biochim Biophys Acta (2003) 0.78
Prion protein protects against DNA damage induced by paraquat in cultured cells. Free Radic Biol Med (2004) 0.78
Effects of di(2-ethylhexyl)phthalate on testicular oxidant/antioxidant status in selenium-deficient and selenium-supplemented rats. Environ Toxicol (2011) 0.78
Chromium III histidinate exposure modulates gene expression in HaCaT human keratinocytes exposed to oxidative stress. Biol Trace Elem Res (2009) 0.77
Prion protein protects against zinc-mediated cytotoxicity by modifying intracellular exchangeable zinc and inducing metallothionein expression. J Trace Elem Med Biol (2009) 0.77
Formation of isodialuric acid lesion within DNA oligomers via one-electron oxidation of 5-hydroxyuracil: characterization, stability and excision repair. Nucleic Acids Res (2006) 0.77
Metallothionein expression in HaCaT and C6 cell lines exposed to cadmium. J Trace Elem Med Biol (2009) 0.77