Published in J Biol Chem on December 23, 2002
The octarepeat domain of the prion protein binds Cu(II) with three distinct coordination modes at pH 7.4. J Am Chem Soc (2005) 1.80
Copper coordination in the full-length, recombinant prion protein. Biochemistry (2003) 1.66
Copper and the prion protein: methods, structures, function, and disease. Annu Rev Phys Chem (2007) 1.56
Copper binding in the prion protein. Acc Chem Res (2004) 1.29
The role of the octarepeat region in neuroprotective function of the cellular prion protein. Brain Pathol (2007) 1.25
Normal cellular prion protein protects against manganese-induced oxidative stress and apoptotic cell death. Toxicol Sci (2007) 1.09
Multiple forms of copper (II) co-ordination occur throughout the disordered N-terminal region of the prion protein at pH 7.4. Biochem J (2006) 0.98
Absence of the cellular prion protein exacerbates and prolongs neuroinflammation in experimental autoimmune encephalomyelitis. Am J Pathol (2008) 0.95
Redox control of prion and disease pathogenesis. Antioxid Redox Signal (2010) 0.93
Functional implications of multistage copper binding to the prion protein. Proc Natl Acad Sci U S A (2009) 0.86
Gene expression profile following stable expression of the cellular prion protein. Cell Mol Neurobiol (2004) 0.86
Identification of the copper(II) coordinating residues in the prion protein by metal-catalyzed oxidation mass spectrometry: evidence for multiple isomers at low copper(II) loadings. Biochemistry (2008) 0.86
Fragmentation and dimerization of copper-loaded prion protein by copper-catalysed oxidation. Biochem J (2005) 0.85
Prion protein and aging. Front Cell Dev Biol (2014) 0.83
Green fluorescent protein as a reporter of prion protein folding. Virol J (2006) 0.82
PRNP M129V homozygosity in multiple system atrophy vs. Parkinson's disease. Clin Auton Res (2008) 0.82
A spectroscopic and voltammetric study of the pH-dependent Cu(II) coordination to the peptide GGGTH: relevance to the fifth Cu(II) site in the prion protein. J Biol Inorg Chem (2006) 0.82
Fragment length influences affinity for Cu2+ and Ni2+ binding to His96 or His111 of the prion protein and spectroscopic evidence for a multiple histidine binding only at low pH. Biochem J (2007) 0.81
Cytosolic caspases mediate mislocalised SOD2 depletion in an in vitro model of chronic prion infection. Dis Model Mech (2013) 0.81
Helicobacter pylori upregulates prion protein expression in gastric mucosa: a possible link to prion disease. World J Gastroenterol (2005) 0.81
Cellular prion protein (PrP(C)) and its role in stress responses. Int J Clin Exp Med (2015) 0.81
Helix 3 is necessary and sufficient for prion protein's anti-Bax function. J Neurochem (2009) 0.80
Analysis of the polymorphic prion protein gene codon 129 in idiopathic Parkinson's disease. J Neural Transm (Vienna) (2005) 0.80
Insights into prion protein function from atomistic simulations. Prion (2010) 0.78
Role of the cellular prion protein in the neuron adaptation strategy to copper deficiency. Cell Mol Neurobiol (2012) 0.77
Real-time kinetics of discontinuous and highly conformational metal-ion binding sites of prion protein. J Biol Inorg Chem (2007) 0.77
Prion protein self-peptides modulate prion interactions and conversion. BMC Biochem (2009) 0.76
Conditional modulation of membrane protein expression in cultured cells mediated by prion protein recognition of short phosphorothioate oligodeoxynucleotides. J Biol Chem (2010) 0.76
Physiological Functions of the Cellular Prion Protein. Front Mol Biosci (2017) 0.75
Gene Signature of Human Oral Mucosa Fibroblasts: Comparison with Dermal Fibroblasts and Induced Pluripotent Stem Cells. Biomed Res Int (2015) 0.75
Copper and Zinc Interactions with Cellular Prion Proteins Change Solubility of Full-Length Glycosylated Isoforms and Induce the Occurrence of Heterogeneous Phenotypes. PLoS One (2016) 0.75
Biological characteristics of Chinese hamster ovary cells transfected with bovine Prnp. J Vet Sci (2007) 0.75
Metal Dyshomeostasis and Their Pathological Role in Prion and Prion-Like Diseases: The Basis for a Nutritional Approach. Front Neurosci (2017) 0.75
Cells release prions in association with exosomes. Proc Natl Acad Sci U S A (2004) 5.17
The SU.VI.MAX Study: a randomized, placebo-controlled trial of the health effects of antioxidant vitamins and minerals. Arch Intern Med (2004) 4.47
Identification and cloning of a beta-cell-specific zinc transporter, ZnT-8, localized into insulin secretory granules. Diabetes (2004) 4.25
In vivo expression and functional characterization of the zinc transporter ZnT8 in glucose-induced insulin secretion. J Cell Sci (2006) 3.82
Antioxidant supplementation increases the risk of skin cancers in women but not in men. J Nutr (2007) 2.66
Screening of 145 anti-PrP monoclonal antibodies for their capacity to inhibit PrPSc replication in infected cells. J Biol Chem (2004) 2.54
A newly identified type of scrapie agent can naturally infect sheep with resistant PrP genotypes. Proc Natl Acad Sci U S A (2005) 2.47
BSE agent signatures in a goat. Vet Rec (2005) 2.35
Facilitated cross-species transmission of prions in extraneural tissue. Science (2012) 2.26
Cyclobutane pyrimidine dimers are predominant DNA lesions in whole human skin exposed to UVA radiation. Proc Natl Acad Sci U S A (2006) 2.19
Prion agent diversity and species barrier. Vet Res (2008) 1.80
Cell specific differences between human adipose-derived and mesenchymal-stromal cells despite similar differentiation potentials. Exp Cell Res (2008) 1.79
Identification of the epitope region capable of inducing neutralizing antibodies against the porcine epidemic diarrhea virus. Mol Cells (2002) 1.77
A bovine prion acquires an epidemic bovine spongiform encephalopathy strain-like phenotype on interspecies transmission. J Neurosci (2007) 1.75
Rejuvenating senescent and centenarian human cells by reprogramming through the pluripotent state. Genes Dev (2011) 1.73
Effect of supplementation with antioxidants upon long-term risk of hypertension in the SU.VI.MAX study: association with plasma antioxidant levels. J Hypertens (2005) 1.67
Standard preanalytical coding for biospecimens: defining the sample PREanalytical code. Cancer Epidemiol Biomarkers Prev (2010) 1.60
The physical relationship between infectivity and prion protein aggregates is strain-dependent. PLoS Pathog (2010) 1.59
Generation of a replication-competent, propagation-deficient virus vector based on the transmissible gastroenteritis coronavirus genome. J Virol (2002) 1.57
Isolation from cattle of a prion strain distinct from that causing bovine spongiform encephalopathy. PLoS Pathog (2006) 1.55
Retrovirus infection strongly enhances scrapie infectivity release in cell culture. EMBO J (2006) 1.53
Stem cell therapy extends incubation and survival time in prion-infected mice in a time window-dependant manner. J Infect Dis (2011) 1.51
Recommendations to standardize preanalytical confounding factors in Alzheimer's and Parkinson's disease cerebrospinal fluid biomarkers: an update. Biomark Med (2012) 1.48
Oxidation of the sugar moiety of DNA by ionizing radiation or bleomycin could induce the formation of a cluster DNA lesion. Proc Natl Acad Sci U S A (2007) 1.47
Enzymatic antioxidant balance and cognitive decline in aging--the EVA study. Eur J Epidemiol (2004) 1.45
Chikungunya fever: CNS infection and pathologies of a re-emerging arbovirus. Prog Neurobiol (2009) 1.44
Soil fungi reduce the iron content and the DNA damaging effects of asbestos fibers. Environ Sci Technol (2006) 1.40
Transmission of atypical bovine prions to mice transgenic for human prion protein. Emerg Infect Dis (2008) 1.38
Transgenesis applied to transmissible spongiform encephalopathies. Transgenic Res (2002) 1.38
Sheep and goat BSE propagate more efficiently than cattle BSE in human PrP transgenic mice. PLoS Pathog (2011) 1.38
Cellular background level of 8-oxo-7,8-dihydro-2'-deoxyguanosine: an isotope based method to evaluate artefactual oxidation of DNA during its extraction and subsequent work-up. Carcinogenesis (2002) 1.36
Mouse neuroblastoma cells release prion infectivity associated with exosomal vesicles. Biol Cell (2008) 1.33
Alpha- and beta- cleavages of the amino-terminus of the cellular prion protein. Biol Cell (2004) 1.33
ZnT-8, a pancreatic beta-cell-specific zinc transporter. Biometals (2005) 1.32
In silico identification and expression of SLC30 family genes: an expressed sequence tag data mining strategy for the characterization of zinc transporters' tissue expression. BMC Genomics (2004) 1.31
Highly efficient prion transmission by blood transfusion. PLoS Pathog (2012) 1.30
Prions can infect primary cultured neurons and astrocytes and promote neuronal cell death. Proc Natl Acad Sci U S A (2004) 1.27
Atypical/Nor98 scrapie infectivity in sheep peripheral tissues. PLoS Pathog (2011) 1.26
Stimulation of PrP(C) retrograde transport toward the endoplasmic reticulum increases accumulation of PrP(Sc) in prion-infected cells. J Biol Chem (2002) 1.25
Prominent and persistent extraneural infection in human PrP transgenic mice infected with variant CJD. PLoS One (2008) 1.24
Exosomes: a bubble ride for prions? Traffic (2005) 1.24
Effects of long-term antioxidant supplementation and association of serum antioxidant concentrations with risk of metabolic syndrome in adults. Am J Clin Nutr (2009) 1.21
Depletion of one, six, twelve or twenty major blood proteins before proteomic analysis: the more the better? J Proteomics (2009) 1.20
Cultured peripheral neuroglial cells are highly permissive to sheep prion infection. J Virol (2004) 1.19
Brain and buffy coat transmission of bovine spongiform encephalopathy to the primate Microcebus murinus. Transfusion (2002) 1.18
Prion protein as trans-interacting partner for neurons is involved in neurite outgrowth and neuronal survival. Mol Cell Neurosci (2003) 1.18
Oxidative stress and the prion protein in transmissible spongiform encephalopathies. Brain Res Brain Res Rev (2002) 1.17
Efficient dissemination of prions through preferential transmission to nearby cells. J Gen Virol (2007) 1.15
Filipin prevents pathological prion protein accumulation by reducing endocytosis and inducing cellular PrP release. J Biol Chem (2002) 1.14
Endogenous proteolytic cleavage of disease-associated prion protein to produce C2 fragments is strongly cell- and tissue-dependent. J Biol Chem (2010) 1.14
Repair of the three main types of bipyrimidine DNA photoproducts in human keratinocytes exposed to UVB and UVA radiations. DNA Repair (Amst) (2005) 1.14
Antihypertensive drug guanabenz is active in vivo against both yeast and mammalian prions. PLoS One (2008) 1.13
Prions and exosomes: from PrPc trafficking to PrPsc propagation. Blood Cells Mol Dis (2005) 1.12
Cerebrospinal fluid collection tubes: a critical issue for Alzheimer disease diagnosis. Clin Chem (2012) 1.11
Characterization of lysine-guanine cross-links upon one-electron oxidation of a guanine-containing oligonucleotide in the presence of a trilysine peptide. J Am Chem Soc (2006) 1.11
Biological and biochemical characteristics of prion strains conserved in persistently infected cell cultures. J Virol (2005) 1.11
Overloaded training increases exercise-induced oxidative stress and damage. Can J Appl Physiol (2003) 1.08
The scrapie prion protein is present in flotillin-1-positive vesicles in central- but not peripheral-derived neuronal cell lines. Eur J Neurosci (2005) 1.07
PrP expression and replication by Schwann cells: implications in prion spreading. J Virol (2002) 1.07
Human biospecimen research: experimental protocol and quality control tools. Cancer Epidemiol Biomarkers Prev (2009) 1.06
Evaluation of cytotoxicity and oxidative DNA damaging effects of di(2-ethylhexyl)-phthalate (DEHP) and mono(2-ethylhexyl)-phthalate (MEHP) on MA-10 Leydig cells and protection by selenium. Toxicol Appl Pharmacol (2010) 1.06
Synovial fluid proteomic fingerprint: S100A8, S100A9 and S100A12 proteins discriminate rheumatoid arthritis from other inflammatory joint diseases. Rheumatology (Oxford) (2010) 1.06
Total plasma carotenoids and mortality in the elderly: results of the Epidemiology of Vascular Ageing (EVA) study. Br J Nutr (2008) 1.05
Marked influence of the route of infection on prion strain apparent phenotype in a scrapie transgenic mouse model. Neurobiol Dis (2010) 1.04
Anti-PrP antibodies block PrPSc replication in prion-infected cell cultures by accelerating PrPC degradation. J Neurochem (2004) 1.04
Prion propagation in cultured cells. Br Med Bull (2003) 1.04
The prion or the related Shadoo protein is required for early mouse embryogenesis. FEBS Lett (2009) 1.03
Predominance of the 1,N2-propano 2'-deoxyguanosine adduct among 4-hydroxy-2-nonenal-induced DNA lesions. Free Radic Biol Med (2004) 1.02
Comparison of protease-resistant prion protein inhibitors in cell cultures infected with two strains of mouse and sheep scrapie. Neurosci Lett (2005) 1.02
Differential regulation of zinc efflux transporters ZnT-1, ZnT-5 and ZnT-7 gene expression by zinc levels: a real-time RT-PCR study. Biochem Pharmacol (2004) 1.02
Correlations between soluble α/β forms of amyloid precursor protein and Aβ38, 40, and 42 in human cerebrospinal fluid. Brain Res (2010) 1.01
PrPc does not mediate internalization of PrPSc but is required at an early stage for de novo prion infection of Rov cells. J Virol (2007) 1.01
First survey of fungi in hypersaline soil and water of Mono Lake area (California). Antonie Van Leeuwenhoek (2004) 1.01
Impact of the 2008-2012 French Alzheimer Plan on the use of cerebrospinal fluid biomarkers in research memory center: the PLM Study. J Alzheimers Dis (2013) 1.00
Cytotoxic effect of ciprofloxacin in primary culture of rat astrocytes and protection by Vitamin E. Toxicology (2006) 1.00
Protein biochip systems for the clinical laboratory. Clin Chem Lab Med (2005) 1.00
Risk of Alzheimer's disease biological misdiagnosis linked to cerebrospinal collection tubes. J Alzheimers Dis (2012) 1.00
Prionemia and leukocyte-platelet-associated infectivity in sheep transmissible spongiform encephalopathy models. J Virol (2011) 1.00
Intersite variability of CSF Alzheimer's disease biomarkers in clinical setting. Alzheimers Dement (2012) 0.99
New in vivo and ex vivo models for the experimental study of sheep scrapie: development and perspectives. C R Biol (2002) 0.99
PrPSc binding antibodies are potent inhibitors of prion replication in cell lines. J Biol Chem (2004) 0.99
Preventive effect of zinc against cadmium-induced oxidative stress in the rat testis. J Reprod Dev (2007) 0.99
Clinical proteomics of the cerebrospinal fluid: Towards the discovery of new biomarkers. Proteomics Clin Appl (2008) 0.99
PrP polymorphisms tightly control sheep prion replication in cultured cells. J Virol (2003) 0.99
Prion infection impairs copper binding of cultured cells. J Biol Chem (2003) 0.99
Protein folding activity of ribosomal RNA is a selective target of two unrelated antiprion drugs. PLoS One (2008) 0.98
Hydroxyl radical is not the main reactive species involved in the degradation of DNA bases by copper in the presence of hydrogen peroxide. Chem Res Toxicol (2003) 0.98