Published in Oncogene on November 04, 2004
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Molecular mechanism of hTid-1, the human homolog of Drosophila tumor suppressor l(2)Tid, in the regulation of NF-kappaB activity and suppression of tumor growth. Mol Cell Biol (2005) 0.88
DNAJB6 chaperones PP2A mediated dephosphorylation of GSK3β to downregulate β-catenin transcription target, osteopontin. Oncogene (2012) 0.87
hTID-1 defines a novel regulator of c-Met Receptor signaling in renal cell carcinomas. Oncogene (2011) 0.85
Tid1 is a Smad-binding protein that can modulate Smad7 activity in developing embryos. Biochem J (2006) 0.79
The tumor suppressor hTid1 inhibits STAT5b activity via functional interaction. J Biol Chem (2010) 0.78
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In vivo evidence of htid suppressive activity on ErbB-2 in breast cancers over expressing the receptor. J Transl Med (2010) 0.75
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Interpreting cancer genomes using systematic host network perturbations by tumour virus proteins. Nature (2012) 4.35
Association of the human papillomavirus type 16 E7 oncoprotein with the 600-kDa retinoblastoma protein-associated factor, p600. Proc Natl Acad Sci U S A (2005) 2.51
The human papillomavirus E7 oncoprotein. Virology (2008) 2.32
Dissection of human papillomavirus E6 and E7 function in transgenic mouse models of cervical carcinogenesis. Cancer Res (2003) 2.32
The human papillomavirus type 16 E6 and E7 oncoproteins independently induce numerical and structural chromosome instability. Cancer Res (2002) 2.16
Mechanisms of genomic instability in human cancer: insights from studies with human papillomavirus oncoproteins. Int J Cancer (2004) 1.90
Bovine papillomavirus E7 transformation function correlates with cellular p600 protein binding. Proc Natl Acad Sci U S A (2005) 1.76
A discrete population of squamocolumnar junction cells implicated in the pathogenesis of cervical cancer. Proc Natl Acad Sci U S A (2012) 1.64
Oncogenic activities of human papillomaviruses. Virus Res (2009) 1.60
The human DEK proto-oncogene is a senescence inhibitor and an upregulated target of high-risk human papillomavirus E7. J Virol (2005) 1.57
Viral perturbations of host networks reflect disease etiology. PLoS Comput Biol (2012) 1.54
Human papillomavirus E7 oncoprotein induces KDM6A and KDM6B histone demethylase expression and causes epigenetic reprogramming. Proc Natl Acad Sci U S A (2011) 1.53
Quantitative role of the human papillomavirus type 16 E5 gene during the productive stage of the viral life cycle. J Virol (2003) 1.49
The human papillomavirus type 16 E6 oncoprotein activates mTORC1 signaling and increases protein synthesis. J Virol (2010) 1.49
Abrogation of the retinoblastoma tumor suppressor checkpoint during keratinocyte immortalization is not sufficient for induction of centrosome-mediated genomic instability. Cancer Res (2003) 1.48
Recapitulation of the effects of the human papillomavirus type 16 E7 oncogene on mouse epithelium by somatic Rb deletion and detection of pRb-independent effects of E7 in vivo. Mol Cell Biol (2003) 1.43
Systematic identification of interactions between host cell proteins and E7 oncoproteins from diverse human papillomaviruses. Proc Natl Acad Sci U S A (2012) 1.33
Human papillomavirus type 16 E7 oncoprotein can induce abnormal centrosome duplication through a mechanism independent of inactivation of retinoblastoma protein family members. J Virol (2003) 1.31
Human papillomavirus type 16 E7 oncoprotein associates with E2F6. J Virol (2008) 1.22
Kinase requirements in human cells: II. Genetic interaction screens identify kinase requirements following HPV16 E7 expression in cancer cells. Proc Natl Acad Sci U S A (2008) 1.17
Endogenous optical biomarkers of normal and human papillomavirus immortalized epithelial cells. Int J Cancer (2008) 1.16
Human papillomavirus 16 E7 inactivator of retinoblastoma family proteins complements human cytomegalovirus lacking UL97 protein kinase. Proc Natl Acad Sci U S A (2009) 1.14
Cullin 1 functions as a centrosomal suppressor of centriole multiplication by regulating polo-like kinase 4 protein levels. Cancer Res (2009) 1.14
Stabilization and functional impairment of the tumor suppressor p53 by the human papillomavirus type 16 E7 oncoprotein. Virology (2002) 1.12
Human papillomaviruses and centrosome duplication errors: modeling the origins of genomic instability. Oncogene (2002) 1.10
Cyclin-dependent kinase inhibitor indirubin-3'-oxime selectively inhibits human papillomavirus type 16 E7-induced numerical centrosome anomalies. Oncogene (2004) 1.07
Human papillomavirus E7 protein deregulates mitosis via an association with nuclear mitotic apparatus protein 1. J Virol (2008) 1.06
Centrosomes, genomic instability, and cervical carcinogenesis. Crit Rev Eukaryot Gene Expr (2003) 1.05
Diagnostic cellular organization features extracted from autofluorescence images. Opt Lett (2007) 1.05
Human papillomavirus type 16 E7 oncoprotein associates with the centrosomal component gamma-tubulin. J Virol (2007) 1.04
Human papillomavirus E7 oncoprotein dysregulates steroid receptor coactivator 1 localization and function. J Virol (2006) 1.03
Intrinsic fluorescence and redox changes associated with apoptosis of primary human epithelial cells. J Biomed Opt (2007) 1.02
NF-kappaB-mediated induction of p21(Cip1/Waf1) by tumor necrosis factor alpha induces growth arrest and cytoprotection in normal human keratinocytes. Mol Cancer Res (2003) 1.02
Id proteins--tumor markers or oncogenes? Cancer Biol Ther (2002) 1.01
Direct association of the HPV16 E7 oncoprotein with cyclin A/CDK2 and cyclin E/CDK2 complexes. Virology (2008) 1.00
HPV16 E7 oncogene expression in normal human epithelial cells causes molecular changes indicative of an epithelial to mesenchymal transition. Virology (2009) 0.99
Ring-opening and ring-closing reactions of a shikimic acid-derived substrate leading to diverse small molecules. J Comb Chem (2007) 0.96
Selective suppression of monocyte chemoattractant protein-1 expression by human papillomavirus E6 and E7 oncoproteins in human cervical epithelial and epidermal cells. Int J Cancer (2003) 0.95
Automated biochemical, morphological, and organizational assessment of precancerous changes from endogenous two-photon fluorescence images. PLoS One (2011) 0.95
The helix-loop-helix protein ID1 localizes to centrosomes and rapidly induces abnormal centrosome numbers. Oncogene (2004) 0.95
Centrosome abnormalities and genomic instability induced by human papillomavirus oncoproteins. Prog Cell Cycle Res (2003) 0.91
Molecular pathways executing the "trophic sentinel" response in HPV-16 E7-expressing normal human diploid fibroblasts upon growth factor deprivation. Virology (2004) 0.91
Aberrations in the MTS1 tumor suppressor locus in oral squamous cell carcinoma lines preferentially affect the INK4A gene and result in increased cdk6 activity. Oral Oncol (2002) 0.91
Human papillomaviruses as therapeutic targets in human cancer. J Clin Oncol (2011) 0.90
Delocalization of the microtubule motor Dynein from mitotic spindles by the human papillomavirus E7 oncoprotein is not sufficient for induction of multipolar mitoses. Cancer Res (2008) 0.89
Clld7, a candidate tumor suppressor on chromosome 13q14, regulates pathways of DNA damage/repair and apoptosis. Cancer Res (2010) 0.87
Excessive centrosome abnormalities without ongoing numerical chromosome instability in a Burkitt's lymphoma. Mol Cancer (2003) 0.87
TID1, a mammalian homologue of the drosophila tumor suppressor lethal(2) tumorous imaginal discs, regulates activation-induced cell death in Th2 cells. Oncogene (2003) 0.86
Expression of a viral oncoprotein in normal human epithelial cells triggers an autophagy-related process: is autophagy an "Achilles' heel" of human cancers? Autophagy (2009) 0.81
Tripeptidyl Peptidase II Is Required for c-MYC-Induced Centriole Overduplication and a Novel Therapeutic Target in c-MYC-Associated Neoplasms. Genes Cancer (2010) 0.79
The human papillomavirus type 8 E2 gene encodes a transforming activity sufficient for skin tumor formation in transgenic mice. J Invest Dermatol (2008) 0.79
Long-term maintenance of human keratinocytes in vitro. J Invest Dermatol (2005) 0.78
Intrinsic fluorescence changes associated with apoptosis of human epithelial keratinocytes. Gynecol Oncol (2005) 0.78
Increased in vitro lifespan of primary human keratinocytes correlates with decreased migration. J Invest Dermatol (2006) 0.77
Make WARTS, not cancer! Oncogene (2004) 0.75