The human papillomavirus E7 oncoprotein.

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Published in Virology on November 12, 2008

Authors

Margaret E McLaughlin-Drubin1, Karl Münger

Author Affiliations

1: Brigham and Women's Hospital and Department of Medicine, Harvard Medical School, Boston, MA 02115, USA. mdrubin@rics.bwh.harvard.edu

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HPV16 E7 oncogene expression in normal human epithelial cells causes molecular changes indicative of an epithelial to mesenchymal transition. Virology (2009) 0.99

Ring-opening and ring-closing reactions of a shikimic acid-derived substrate leading to diverse small molecules. J Comb Chem (2007) 0.96

The helix-loop-helix protein ID1 localizes to centrosomes and rapidly induces abnormal centrosome numbers. Oncogene (2004) 0.95

Automated biochemical, morphological, and organizational assessment of precancerous changes from endogenous two-photon fluorescence images. PLoS One (2011) 0.95

Selective suppression of monocyte chemoattractant protein-1 expression by human papillomavirus E6 and E7 oncoproteins in human cervical epithelial and epidermal cells. Int J Cancer (2003) 0.95

Molecular pathways executing the "trophic sentinel" response in HPV-16 E7-expressing normal human diploid fibroblasts upon growth factor deprivation. Virology (2004) 0.91

Aberrations in the MTS1 tumor suppressor locus in oral squamous cell carcinoma lines preferentially affect the INK4A gene and result in increased cdk6 activity. Oral Oncol (2002) 0.91

Centrosome abnormalities and genomic instability induced by human papillomavirus oncoproteins. Prog Cell Cycle Res (2003) 0.91

Human papillomaviruses as therapeutic targets in human cancer. J Clin Oncol (2011) 0.90

Delocalization of the microtubule motor Dynein from mitotic spindles by the human papillomavirus E7 oncoprotein is not sufficient for induction of multipolar mitoses. Cancer Res (2008) 0.89

Clld7, a candidate tumor suppressor on chromosome 13q14, regulates pathways of DNA damage/repair and apoptosis. Cancer Res (2010) 0.87

Excessive centrosome abnormalities without ongoing numerical chromosome instability in a Burkitt's lymphoma. Mol Cancer (2003) 0.87

TID1, a mammalian homologue of the drosophila tumor suppressor lethal(2) tumorous imaginal discs, regulates activation-induced cell death in Th2 cells. Oncogene (2003) 0.86

Depletion of physiological levels of the human TID1 protein renders cancer cell lines resistant to apoptosis mediated by multiple exogenous stimuli. Oncogene (2004) 0.85

Expression of a viral oncoprotein in normal human epithelial cells triggers an autophagy-related process: is autophagy an "Achilles' heel" of human cancers? Autophagy (2009) 0.81

The human papillomavirus type 8 E2 gene encodes a transforming activity sufficient for skin tumor formation in transgenic mice. J Invest Dermatol (2008) 0.79

Tripeptidyl Peptidase II Is Required for c-MYC-Induced Centriole Overduplication and a Novel Therapeutic Target in c-MYC-Associated Neoplasms. Genes Cancer (2010) 0.79

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Intrinsic fluorescence changes associated with apoptosis of human epithelial keratinocytes. Gynecol Oncol (2005) 0.78

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Make WARTS, not cancer! Oncogene (2004) 0.75