Block of HERG current expressed in HEK293 cells by the Na+-channel blocker cibenzoline.

PubWeight™: 0.75‹?›

🔗 View Article (PMID 15168062)

Published in Heart Vessels on May 01, 2004

Authors

Mikio Hiramatsu1, Long-Mei Wu, Yuji Hirano, Seiko Kawano, Tetsushi Furukawa, Masayasu Hiraoka

Author Affiliations

1: Department of Cardiovascular Disease, Medical Research Institute, Tokyo Medical and Dental University, 1-5-45 Yushima, Bunkyo-ku, Tokyo 113-8510, Japan.

Articles by these authors

Meta-analysis identifies six new susceptibility loci for atrial fibrillation. Nat Genet (2012) 3.71

Disease characterization using LQTS-specific induced pluripotent stem cells. Cardiovasc Res (2012) 1.95

Drugs and Brugada syndrome patients: review of the literature, recommendations, and an up-to-date website (www.brugadadrugs.org). Heart Rhythm (2009) 1.92

Functional characterization of a trafficking-defective HCN4 mutation, D553N, associated with cardiac arrhythmia. J Biol Chem (2004) 1.75

Reentrant tachycardia in pulmonary veins of patients with paroxysmal atrial fibrillation. J Cardiovasc Electrophysiol (2003) 1.57

Identification and characterization of the slowly exchanging pH-dependent conformational rearrangement in KcsA. J Biol Chem (2007) 1.50

The prognostic value of early repolarization (J wave) and ST-segment morphology after J wave in Brugada syndrome: multicenter study in Japan. Heart Rhythm (2012) 1.49

Progesterone regulates cardiac repolarization through a nongenomic pathway: an in vitro patch-clamp and computational modeling study. Circulation (2007) 1.48

Ambulatory ECG-based T-wave alternans and heart rate turbulence predict high risk of arrhythmic events in patients with old myocardial infarction. Circ J (2009) 1.45

J wave and fragmented QRS formation during the hyperacute phase in Takotsubo cardiomyopathy. Circ J (2014) 1.44

Unmasking Brugada-type electrocardiogram on deep inspiration. Circ J (2013) 1.40

Fragmented QRS predicts cardiovascular death of patients with structural heart disease and inducible ventricular tachyarrhythmia. Circ J (2013) 1.40

Identical atrio-His interval and A-A intervals during long RP tachycardia: what is the mechanism? Diagnosis: Atypical AVNRT. Circ Arrhythm Electrophysiol (2014) 1.39

Association of atrial arrhythmia and sinus node dysfunction in patients with catecholaminergic polymorphic ventricular tachycardia. Circ J (2007) 1.38

Resolution of abnormal body surface maps in children with atrial septal defect after intracardiac repair. J Cardiovasc Electrophysiol (2004) 1.38

Nontranscriptional regulation of cardiac repolarization currents by testosterone. Circulation (2005) 1.32

Acute effects of oestrogen on the guinea pig and human IKr channels and drug-induced prolongation of cardiac repolarization. J Physiol (2008) 1.28

Electrical connections between pulmonary veins: implication for ostial ablation of pulmonary veins in patients with paroxysmal atrial fibrillation. Circulation (2002) 1.20

Macroreentrant atrial tachycardia in patients without previous atrial surgery or catheter ablation: clinical and electrophysiological characteristics of scar-related left atrial anterior wall reentry. J Cardiovasc Electrophysiol (2012) 1.19

Aquaporin-2 trafficking is regulated by PDZ-domain containing protein SPA-1. FEBS Lett (2004) 1.18

Role of nitric oxide in Ca2+ sensitivity of the slowly activating delayed rectifier K+ current in cardiac myocytes. Circ Res (2004) 1.15

Complex anatomy surrounding the left atrial posterior wall: analysis with 3D computed tomography. Heart Vessels (2011) 1.12

Integrating genetic, transcriptional, and functional analyses to identify 5 novel genes for atrial fibrillation. Circulation (2014) 1.11

A mutant cardiac sodium channel with multiple biophysical defects associated with overlapping clinical features of Brugada syndrome and cardiac conduction disease. Cardiovasc Res (2002) 1.06

Clinical effectiveness of pulmonary vein isolation for arrhythmic events in a patient with catecholaminergic polymorphic ventricular tachycardia. Heart Vessels (2010) 1.05

Redox- and calmodulin-dependent S-nitrosylation of the KCNQ1 channel. J Biol Chem (2009) 1.05

Nitric oxide-dependent modulation of the delayed rectifier K+ current and the L-type Ca2+ current by ginsenoside Re, an ingredient of Panax ginseng, in guinea-pig cardiomyocytes. Br J Pharmacol (2004) 1.05

Ca(2+) oscillations regulated by Na(+)-Ca(2+) exchanger and plasma membrane Ca(2+) pump induce fluctuations of membrane currents and potentials in human mesenchymal stem cells. Cell Calcium (2003) 1.02

ClC-3B, a novel ClC-3 splicing variant that interacts with EBP50 and facilitates expression of CFTR-regulated ORCC. FASEB J (2002) 1.02

A novel disease gene for Brugada syndrome: sarcolemmal membrane-associated protein gene mutations impair intracellular trafficking of hNav1.5. Circ Arrhythm Electrophysiol (2012) 1.02

A new echocardiographic method for identifying vortex flow in the left ventricle: numerical validation. Ultrasound Med Biol (2010) 1.01

Structural basis of the KcsA K(+) channel and agitoxin2 pore-blocking toxin interaction by using the transferred cross-saturation method. Structure (2003) 0.98

Truncated KCNQ1 mutant, A178fs/105, forms hetero-multimer channel with wild-type causing a dominant-negative suppression due to trafficking defect. FEBS Lett (2004) 0.97

Role of HCN4 channel in preventing ventricular arrhythmia. J Hum Genet (2009) 0.97

Effects of glucose-induced insulin secretion on ST segment elevation in the Brugada syndrome. J Cardiovasc Electrophysiol (2003) 0.95

Role of transient receptor potential vanilloid 2 in LPS-induced cytokine production in macrophages. Biochem Biophys Res Commun (2010) 0.95

An autocrine/paracrine loop linking keratin 14 aggregates to tumor necrosis factor alpha-mediated cytotoxicity in a keratinocyte model of epidermolysis bullosa simplex. J Biol Chem (2003) 0.95

Acute effects of sex steroid hormones on susceptibility to cardiac arrhythmias: a simulation study. PLoS Comput Biol (2010) 0.94

Functional expression of Ca2+ signaling pathways in mouse embryonic stem cells. Cell Calcium (2004) 0.94

Reciprocal control of hERG stability by Hsp70 and Hsc70 with implication for restoration of LQT2 mutant stability. Circ Res (2010) 0.92

Effects of low-dose quinidine on ventricular tachyarrhythmias in patients with Brugada syndrome: low-dose quinidine therapy as an adjunctive treatment. J Cardiovasc Pharmacol (2006) 0.92

Bioluminescent indicators for Ca2+ based on split Renilla luciferase complementation in living cells. Anal Sci (2008) 0.92

Clinical efficacy of abatacept compared to adalimumab and tocilizumab in rheumatoid arthritis patients with high disease activity. Clin Rheumatol (2013) 0.90

Study protocol of a multicenter registry of patients with rheumatoid arthritis starting biologic therapy in Japan: Tsurumai Biologics Communication Registry (TBCR) study. Mod Rheumatol (2011) 0.90

Electrophysiological effects of ginseng and ginsenoside Re in guinea pig ventricular myocytes. Eur J Pharmacol (2003) 0.89

High incidence of device-related and lead-related complications in the dual-chamber implantable cardioverter defibrillator compared with the single-chamber version. Circ J (2002) 0.89

Clinical characteristics and risk stratification in symptomatic and asymptomatic patients with brugada syndrome: multicenter study in Japan. J Cardiovasc Electrophysiol (2007) 0.89

Effects of Na+ channel blocker, pilsicainide, on HERG current expressed in HEK-293 cells. J Cardiovasc Pharmacol (2003) 0.89

Low risk for arrhythmic events in asymptomatic patients with drug-induced type 1 ECG. Do patients with drug-induced Brugada type ECG have poor prognosis? (Con). Circ J (2010) 0.88

A novel action of insulin on cardiac membrane. Circ Res (2003) 0.86

M phase-specific expression and phosphorylation-dependent ubiquitination of the ClC-2 channel. J Biol Chem (2002) 0.86

A novel mutation in KCNQ1 associated with a potent dominant negative effect as the basis for the LQT1 form of the long QT syndrome. J Cardiovasc Electrophysiol (2007) 0.86

KCNE variants reveal a critical role of the beta subunit carboxyl terminus in PKA-dependent regulation of the IKs potassium channel. Channels (Austin) (2009) 0.86

Hsp90 prevents interaction between CHIP and HERG proteins to facilitate maturation of wild-type and mutant HERG proteins. Cardiovasc Res (2013) 0.85

Profiling of serum metabolites in canine lymphoma using gas chromatography mass spectrometry. J Vet Med Sci (2014) 0.85

Na+/K+ ATPase and its functional coupling with Na+/Ca2+ exchanger in mouse embryonic stem cells during differentiation into cardiomyocytes. Cell Calcium (2005) 0.84

Is the ClC-2 chloride channel involved in the Cl- secretory mechanism of gastric parietal cells? FEBS Lett (2004) 0.84

Anti-KCNH2 antibody-induced long QT syndrome: novel acquired form of long QT syndrome. J Am Coll Cardiol (2007) 0.84

Unexpected mexiletine responses of a mutant cardiac Na+ channel implicate the selectivity filter as a structural determinant of antiarrhythmic drug access. Mol Pharmacol (2004) 0.83

Spontaneous T wave alternans in a patient with Brugada syndrome--responses to intravenous administration of class I antiarrhythmic drug, glucose tolerance test, and atrial pacing. J Cardiovasc Electrophysiol (2005) 0.83

A genetically encoded bioluminescent indicator for the sodium channel activity in living cells. J Am Chem Soc (2009) 0.83

Ambulatory electrocardiogram-based T-wave alternans in patients with vasospastic angina during asymptomatic periods. Am J Cardiol (2012) 0.83

Diffusion property differences of the lower leg musculature between athletes and non-athletes using 1.5T MRI. MAGMA (2011) 0.83

Clinical and electrophysiological characteristics in patients with sustained monomorphic reentrant ventricular tachycardia associated with dilated-phase hypertrophic cardiomyopathy. Europace (2011) 0.82

Synergic effects of β-estradiol and erythromycin on hERG currents. J Membr Biol (2011) 0.82

Monitoring C-reactive protein levels to predict favourable clinical outcomes from tocilizumab treatment in patients with rheumatoid arthritis. Mod Rheumatol (2012) 0.82

Early aggressive intervention with tocilizumab for rheumatoid arthritis increases remission rate defined using a Boolean approach in clinical practice. Mod Rheumatol (2011) 0.82

Prophylactic catheter ablation for induced monomorphic ventricular tachycardia in patients with implantable cardioverter defibrillators as primary prevention. Europace (2013) 0.82

Cl- channel blockers inhibit transition of quiescent (G0) fibroblasts into the cell cycle. J Cell Physiol (2003) 0.82

Ion channel remodeling in cardiac hypertrophy is prevented by blood pressure reduction without affecting heart weight increase in rats with abdominal aortic banding. J Cardiovasc Pharmacol (2002) 0.82

Clinical efficacy of abatacept in Japanese rheumatoid arthritis patients. Mod Rheumatol (2012) 0.82

Clinical efficacy of abatacept, tocilizumab, and etanercept in Japanese rheumatoid arthritis patients with inadequate response to anti-TNF monoclonal antibodies. Clin Rheumatol (2014) 0.82

Region- and condition-dependence of the membrane and Ca2+ clocks in the sinus node. Circ J (2011) 0.81

Anti-arrhythmic efficacy of nifekalant hydrochloride, a pure class III anti-arrhythmic agent, in patients with healed myocardial infarction and inducible sustained ventricular tachycardia. J Cardiovasc Pharmacol (2002) 0.81

Twenty-four-week clinical results of adalimumab therapy in Japanese patients with rheumatoid arthritis: retrospective analysis for the best use of adalimumab in daily practice. Mod Rheumatol (2012) 0.80

Stretch of atrial myocytes stimulates recruitment of macrophages via ATP released through gap-junction channels. J Pharmacol Sci (2012) 0.80

Effects of an hERG activator, ICA-105574, on electrophysiological properties of canine hearts. J Pharmacol Sci (2012) 0.80

A receptor-independent effect of estrone sulfate on the HERG channel. J Pharmacol Sci (2009) 0.80

Ca2+ entry-dependent inactivation of L-type Ca current: a novel formulation for cardiac action potential models. Biophys J (2003) 0.80

Calcium-activated CL- current is enhanced by acidosis and contributes to the shortening of action potential duration in rabbit ventricular myocytes. Jpn J Physiol (2002) 0.80

Classification and assessment of computerized diagnostic criteria for Brugada-type electrocardiograms. Heart Rhythm (2010) 0.80

Correlation between pennation angle and image quality of skeletal muscle fibre tractography using deterministic diffusion tensor imaging. J Med Imaging Radiat Oncol (2012) 0.80

Calcium channel blocker and adenosine triphosphate terminate bidirectional ventricular tachycardia in a patient with Andersen-Tawil syndrome. Heart Rhythm (2007) 0.79

Electrical connection between left superior and inferior pulmonary veins in a patient with paroxysmal atrial fibrillation. J Cardiovasc Electrophysiol (2002) 0.79

Influence of meals on variations of ST segment elevation in patients with Brugada syndrome. J Cardiovasc Electrophysiol (2007) 0.79

The mouse sino-atrial node expresses both the type 2 and type 3 Ca(2+) release channels/ryanodine receptors. FEBS Lett (2003) 0.79

Human cardiac ryanodine receptor mutations in ion channel disorders in Japan. Int J Cardiol (2006) 0.79

Novel C-terminus frameshift mutation, 1122fs/147, of HERG in LQT2: additional amino acids generated by frameshift cause accelerated inactivation. J Mol Cell Cardiol (2004) 0.78

Changes in body surface potential distributions induced by isoproterenol and Na channel blockers in patients with the Brugada syndrome. Int J Cardiol (2004) 0.78