Published in Circulation on December 03, 2007
Potential depot medroxyprogesterone acetate-triggered torsades de pointes in a case of congenital type 2 long QT syndrome. Heart Rhythm (2012) 2.09
Clinical and genetic determinants of torsade de pointes risk. Circulation (2012) 1.67
Risk of recurrent cardiac events after onset of menopause in women with congenital long-QT syndrome types 1 and 2. Circulation (2011) 1.41
Caveolae, ion channels and cardiac arrhythmias. Prog Biophys Mol Biol (2009) 1.35
Acute effects of oestrogen on the guinea pig and human IKr channels and drug-induced prolongation of cardiac repolarization. J Physiol (2008) 1.28
Caveolae create local signalling domains through their distinct protein content, lipid profile and morphology. J Mol Cell Cardiol (2011) 1.05
Computational approaches to understand cardiac electrophysiology and arrhythmias. Am J Physiol Heart Circ Physiol (2012) 1.05
Long QT syndrome: beyond the causal mutation. J Physiol (2013) 1.00
Computational models reduce complexity and accelerate insight into cardiac signaling networks. Circ Res (2011) 1.00
Computational cardiology: the heart of the matter. ISRN Cardiol (2012) 0.96
Sex differences in mechanisms of cardiac excitation-contraction coupling. Pflugers Arch (2013) 0.94
Acute effects of sex steroid hormones on susceptibility to cardiac arrhythmias: a simulation study. PLoS Comput Biol (2010) 0.94
In silico prediction of drug therapy in catecholaminergic polymorphic ventricular tachycardia. J Physiol (2015) 0.92
Progesterone impairs human ether-a-go-go-related gene (HERG) trafficking by disruption of intracellular cholesterol homeostasis. J Biol Chem (2011) 0.90
Atrial fibrillation in women: epidemiology, pathophysiology, presentation, and prognosis. Nat Rev Cardiol (2016) 0.89
Re-evaluating the efficacy of beta-adrenergic agonists and antagonists in long QT-3 syndrome through computational modelling. Cardiovasc Res (2009) 0.87
Influence of progesterone on endometrial nitric oxide synthase expression. Fertil Steril (2008) 0.87
Sex hormones and the QT interval: a review. J Womens Health (Larchmt) (2012) 0.86
Oestrogen upregulates L-type Ca²⁺ channels via oestrogen-receptor- by a regional genomic mechanism in female rabbit hearts. J Physiol (2011) 0.86
Computational cardiology: how computer simulations could be used to develop new therapies and advance existing ones. Europace (2012) 0.85
Molecular Pathophysiology of Congenital Long QT Syndrome. Physiol Rev (2017) 0.85
In silico Prediction of Sex-Based Differences in Human Susceptibility to Cardiac Ventricular Tachyarrhythmias. Front Physiol (2012) 0.84
Pregnenolone sulphate-independent inhibition of TRPM3 channels by progesterone. Cell Calcium (2011) 0.83
Gender differences in factors influencing electrocardiographic findings of left ventricular hypertrophy in severe aortic stenosis. Heart Vessels (2013) 0.82
A long QT mutation substitutes cholesterol for phosphatidylinositol-4,5-bisphosphate in KCNQ1 channel regulation. PLoS One (2014) 0.81
Sex-specific modification of progesterone receptor expression by 17β-oestradiol in human cardiac tissues. Biol Sex Differ (2010) 0.81
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Oral contraceptive use and the risk of cardiac events in patients with long QT syndrome. Heart Rhythm (2014) 0.77
Rabbit-specific computational modelling of ventricular cell electrophysiology: Using populations of models to explore variability in the response to ischemia. Prog Biophys Mol Biol (2016) 0.77
Computational Models for Predictive Cardiac Ion Channel Pharmacology. Drug Discov Today Dis Models (2014) 0.76
Sex hormonal regulation of cardiac ion channels in drug-induced QT syndromes. Pharmacol Ther (2016) 0.75
A Combined Approach Using Patch-Clamp Study and Computer Simulation Study for Understanding Long QT Syndrome and TdP in Women. Curr Cardiol Rev (2008) 0.75
Long QTc Syndrome Type 2 Presenting in a Postpartum Patient on Medroxyprogesterone. Case Rep Cardiol (2014) 0.75
Progesterone modulates SERCA2a expression and function in rabbit cardiomyocytes. Am J Physiol Cell Physiol (2014) 0.75
Influence of Oral Progesterone Administration on Drug-Induced QT Interval Lengthening: A Randomized, Double-Blind, Placebo-Controlled Crossover Study. JACC Clin Electrophysiol (2016) 0.75
Acute exposure to progesterone attenuates cardiac contraction by modifying myofilament calcium sensitivity in the female mouse heart. Am J Physiol Heart Circ Physiol (2016) 0.75
Microdomain-specific localization of functional ion channels in cardiomyocytes: an emerging concept of local regulation and remodelling. Biophys Rev (2015) 0.75
Adult Ventricular Myocytes Segregate KCNQ1 and KCNE1 to Keep the IKs Amplitude in Check Until When Larger IKs Is Needed. Circ Arrhythm Electrophysiol (2017) 0.75
Roles and indications for use of implantable defibrillator and resynchronization therapy in the prevention of sudden cardiac death in heart failure. Heart Fail Rev (2016) 0.75
Progesterone Protects Against Bisphenol A-Induced Arrhythmias in Female Rat Cardiac Myocytes via Rapid Signaling. Endocrinology (2017) 0.75
A multiscale computational modelling approach predicts mechanisms of female sex risk in the setting of arousal-induced arrhythmias. J Physiol (2017) 0.75
The MicroArray Quality Control (MAQC) project shows inter- and intraplatform reproducibility of gene expression measurements. Nat Biotechnol (2006) 30.90
A model of (often mixed) stereotype content: competence and warmth respectively follow from perceived status and competition. J Pers Soc Psychol (2002) 7.36
Rat toxicogenomic study reveals analytical consistency across microarray platforms. Nat Biotechnol (2006) 5.14
Pluripotent stem cells induced from mouse somatic cells by small-molecule compounds. Science (2013) 4.94
Requirement of a macromolecular signaling complex for beta adrenergic receptor modulation of the KCNQ1-KCNE1 potassium channel. Science (2002) 4.49
Variant of SCN5A sodium channel implicated in risk of cardiac arrhythmia. Science (2002) 4.40
Meta-analysis identifies six new susceptibility loci for atrial fibrillation. Nat Genet (2012) 3.71
Simultaneous phase and size control of upconversion nanocrystals through lanthanide doping. Nature (2010) 3.53
Histone H3 and H4 ubiquitylation by the CUL4-DDB-ROC1 ubiquitin ligase facilitates cellular response to DNA damage. Mol Cell (2006) 3.39
Cancer siRNA therapy by tumor selective delivery with ligand-targeted sterically stabilized nanoparticle. Nucleic Acids Res (2004) 3.03
NOTCH reprograms mitochondrial metabolism for proinflammatory macrophage activation. J Clin Invest (2015) 2.93
Integrative genomic and functional analyses reveal neuronal subtype differentiation bias in human embryonic stem cell lines. Proc Natl Acad Sci U S A (2007) 2.60
Using siRNA in prophylactic and therapeutic regimens against SARS coronavirus in Rhesus macaque. Nat Med (2005) 2.55
Expectation-maximization-driven geodesic active contour with overlap resolution (EMaGACOR): application to lymphocyte segmentation on breast cancer histopathology. IEEE Trans Biomed Eng (2010) 2.52
A global in vivo Drosophila RNAi screen identifies NOT3 as a conserved regulator of heart function. Cell (2010) 2.27
Genome-wide association analysis identifies new lung cancer susceptibility loci in never-smoking women in Asia. Nat Genet (2012) 2.26
Targeted synthesis of a porous aromatic framework with high stability and exceptionally high surface area. Angew Chem Int Ed Engl (2009) 2.22
Osteopontin deficiency does not prevent but promotes alcoholic neutrophilic hepatitis in mice. Hepatology (2014) 2.17
Impact of plaque morphology on creatine kinase-MB elevation in patients with elective stent implantation. Int J Cardiol (2010) 2.05
Clinical short-term results of radiofrequency ablation in liver cancers. World J Gastroenterol (2002) 2.04
Inhibition of IkappaB phosphorylation in cardiomyocytes attenuates myocardial ischemia/reperfusion injury. Cardiovasc Res (2004) 1.99
Genome-wide analysis uncovers regulation of long intergenic noncoding RNAs in Arabidopsis. Plant Cell (2012) 1.99
Late-phase thromboembolism after catheter ablation for paroxysmal atrial fibrillation. Circ J (2014) 1.98
Impact of statin use before the onset of acute myocardial infarction on coronary plaque morphology of the culprit lesion. Angiology (2012) 1.97
Disease characterization using LQTS-specific induced pluripotent stem cells. Cardiovasc Res (2012) 1.95
Endogenous histones function as alarmins in sterile inflammatory liver injury through Toll-like receptor 9 in mice. Hepatology (2011) 1.94
Mst1 inhibits autophagy by promoting the interaction between Beclin1 and Bcl-2. Nat Med (2013) 1.93
Clinical implications of reconnection between the left atrium and isolated pulmonary veins provoked by adenosine triphosphate after extensive encircling pulmonary vein isolation. J Cardiovasc Electrophysiol (2007) 1.88
Culture, distress, and oxytocin receptor polymorphism (OXTR) interact to influence emotional support seeking. Proc Natl Acad Sci U S A (2010) 1.79
Sex chromosome complement and gonadal sex influence aggressive and parental behaviors in mice. J Neurosci (2006) 1.78
A computational model to predict the effects of class I anti-arrhythmic drugs on ventricular rhythms. Sci Transl Med (2011) 1.78
Effect of sodium-channel blockade on early repolarization in inferior/lateral leads in patients with idiopathic ventricular fibrillation and Brugada syndrome. Heart Rhythm (2011) 1.71
Inhibition of ocular angiogenesis by siRNA targeting vascular endothelial growth factor pathway genes: therapeutic strategy for herpetic stromal keratitis. Am J Pathol (2004) 1.70
Impact of adenosine-provoked acute dormant pulmonary vein conduction on recurrence of atrial fibrillation. J Cardiovasc Electrophysiol (2011) 1.70
Ultrasound-microbubble-mediated intercellular adhesion molecule-1 small interfering ribonucleic acid transfection attenuates neointimal formation after arterial injury in mice. J Am Coll Cardiol (2010) 1.68
Complex spatial distribution and dynamics of an abundant Escherichia coli outer membrane protein, LamB. Mol Microbiol (2004) 1.66
Characterization of cytokine/chemokine profiles of severe acute respiratory syndrome. Am J Respir Crit Care Med (2005) 1.66
Prevalence and distribution of sarcomeric gene mutations in Japanese patients with familial hypertrophic cardiomyopathy. Circ J (2011) 1.64
Genes that escape from X inactivation. Hum Genet (2011) 1.63
Adiponectin protects against doxorubicin-induced cardiomyopathy by anti-apoptotic effects through AMPK up-regulation. Cardiovasc Res (2010) 1.63
Local unipolar and bipolar electrogram criteria for evaluating the transmurality of atrial ablation lesions at different catheter orientations relative to the endocardial surface. Heart Rhythm (2010) 1.61
The biosynthetic gene cluster of the maytansinoid antitumor agent ansamitocin from Actinosynnema pretiosum. Proc Natl Acad Sci U S A (2002) 1.61
Nitric oxide inhibits ischemia/reperfusion-induced myocardial apoptosis by modulating cyclin A-associated kinase activity. Cardiovasc Res (2003) 1.60
Ultrabroadband light absorption by a sawtooth anisotropic metamaterial slab. Nano Lett (2012) 1.59
Autonomic control of cardiac action potentials: role of potassium channel kinetics in response to sympathetic stimulation. Circ Res (2005) 1.58
Computer-aided detection and diagnosis of breast cancer with mammography: recent advances. IEEE Trans Inf Technol Biomed (2009) 1.58
Cardiomyocyte proliferation and protection against post-myocardial infarction heart failure by cyclin D1 and Skp2 ubiquitin ligase. Cardiovasc Res (2008) 1.57
Long-term clinical outcome of extensive pulmonary vein isolation-based catheter ablation therapy in patients with paroxysmal and persistent atrial fibrillation. Heart (2010) 1.55
Comparative genome analysis of Trichophyton rubrum and related dermatophytes reveals candidate genes involved in infection. MBio (2012) 1.55
Increase in activated protein C mediates acute traumatic coagulopathy in mice. Shock (2009) 1.53
Renal function after catheter ablation of atrial fibrillation. Circulation (2011) 1.53
The CRISPR/Cas system mediates efficient genome engineering in Bombyx mori. Cell Res (2013) 1.52
Gender and age differences in candidates for radiofrequency catheter ablation of idiopathic ventricular arrhythmias. Circ J (2011) 1.51
New human leukocyte antigen risk allele in Japanese patients with Takayasu arteritis. Circ J (2012) 1.51
Ribosome engineering and secondary metabolite production. Adv Appl Microbiol (2004) 1.51
Cucurbitacin B regulates immature myeloid cell differentiation and enhances antitumor immunity in patients with lung cancer. Cancer Biother Radiopharm (2012) 1.51
Discovery of molecular mechanisms of traditional Chinese medicinal formula Si-Wu-Tang using gene expression microarray and connectivity map. PLoS One (2011) 1.49
Incidence of late thromboembolic events after catheter ablation of atrial fibrillation. Circ J (2011) 1.48
Detection of epithelial to mesenchymal transition in airways of a bleomycin induced pulmonary fibrosis model derived from an alpha-smooth muscle actin-Cre transgenic mouse. Respir Res (2007) 1.46
Toll-like receptor-2 plays a fundamental role in periodontal bacteria-accelerated abdominal aortic aneurysms. Circ J (2013) 1.46
Clinical study regarding the anatomical structures of the right atrial isthmus using intra-cardiac echocardiography: implication for catheter ablation of common atrial flutter. J Interv Card Electrophysiol (2005) 1.45
Ambulatory ECG-based T-wave alternans and heart rate turbulence predict high risk of arrhythmic events in patients with old myocardial infarction. Circ J (2009) 1.45
J wave and fragmented QRS formation during the hyperacute phase in Takotsubo cardiomyopathy. Circ J (2014) 1.44
Assessment of echo-attenuated plaque by optical coherence tomography and its impact on post-procedural creatine kinase-myocardial band elevation in elective stent implantation. JACC Cardiovasc Interv (2011) 1.44
Pitavastatin suppresses acute and chronic rejection in murine cardiac allografts. Transplantation (2007) 1.44
Kinesin spindle protein inhibitor SB743921 induces mitotic arrest and apoptosis and overcomes imatinib resistance of chronic myeloid leukemia cells. Leuk Lymphoma (2014) 1.44
Pedicled deep inferior epigastric perforator flap: an alternative method to repair groin and scrotal defects. Ann Plast Surg (2006) 1.43
Additive effects of β-blockers on renin-angiotensin system inhibitors for patients after acute myocardial infarction treated with primary coronary revascularization. Circ J (2011) 1.43
Early treatment with clarithromycin attenuates rat autoimmune myocarditis via inhibition of matrix metalloproteinase activity. Heart (2010) 1.43
Catheter ablation of atrial fibrillation in patients with valvular heart disease: long-term follow-up results. J Cardiovasc Electrophysiol (2010) 1.42
Perindopril augments ecto-ATP diphosphohydrolase activity and enhances endothelial anti-platelet function in human umbilical vein endothelial cells. J Hypertens (2003) 1.42
Utility of distinctive local electrogram pattern and aortographic anatomical position in catheter manipulation at coronary cusps. J Cardiovasc Electrophysiol (2010) 1.41
Evaluation by indirect immunofluorescent assay and enzyme linked immunosorbent assay of the dynamic changes of serum antibody responses against severe acute respiratory syndrome coronavirus. Chin Med J (Engl) (2005) 1.41
Variability of microcirculatory resistance index and its relationship with fractional flow reserve in patients with intermediate coronary artery lesions. Circ J (2013) 1.41
Synergistic effect of combined HMG-CoA reductase inhibitor and angiotensin-II receptor blocker therapy in patients with chronic heart failure: the HF-COSTAR trial. Circ J (2011) 1.40
Clinical utility of adenosine-infusion test at a repeat atrial fibrillation ablation procedure. Heart Rhythm (2012) 1.40
Directed differentiation of human embryonic stem cells into thymic epithelial progenitor-like cells reconstitutes the thymic microenvironment in vivo. Cell Stem Cell (2013) 1.40
Detection of epidermal growth factor receptor mutations in plasma by mutant-enriched PCR assay for prediction of the response to gefitinib in patients with non-small-cell lung cancer. Int J Cancer (2009) 1.40
Synthesis, characterization, antioxidant activities, and DNA-binding studies of (E)-N'-[1-(pyridin-2-yl)ethylidene]isonicotinohydrazide and its Pr(III) and Nd(III) complexes. Chem Pharm Bull (Tokyo) (2010) 1.40
Current state of symptomatic aortic valve stenosis in the Japanese elderly. Circ J (2011) 1.39
Electrocardiography characteristics of isolated non-compaction of ventricular myocardium in Japanese adult patients. Circ J (2010) 1.39
Clinical assessment of antiarrhythmic agents for paroxysmal atrial fibrillation guided by modification of electrophysiologic arrhythmogenicity. J Cardiovasc Electrophysiol (2004) 1.39
Clinical effect of implantable cardioverter defibrillator replacements: when should you resume driving after an implantable cardioverter defibrillator replacement? Circ J (2010) 1.39
Astrocytic glutamate release-induced transient depolarization and epileptiform discharges in hippocampal CA1 pyramidal neurons. J Neurophysiol (2005) 1.39
Amiodarone-induced thyrotoxicosis late after amiodarone withdrawal. Circ J (2013) 1.38
Near-infrared to mid-infrared photoluminescence of Bi2O3-GeO2 binary glasses. Opt Lett (2012) 1.38
Influence of microvascular resistance on fractional flow reserve after successful percutaneous coronary intervention. Catheter Cardiovasc Interv (2014) 1.38
First identification of the hepatotoxic microcystins in the serum of a chronically exposed human population together with indication of hepatocellular damage. Toxicol Sci (2009) 1.37
Stacked Sparse Autoencoder (SSAE) for Nuclei Detection on Breast Cancer Histopathology Images. IEEE Trans Med Imaging (2015) 1.37
Differential but convergent functions of Ca2+ binding to synaptotagmin-1 C2 domains mediate neurotransmitter release. Proc Natl Acad Sci U S A (2009) 1.37
Two cap-binding proteins CBP20 and CBP80 are involved in processing primary MicroRNAs. Plant Cell Physiol (2008) 1.35
Identification of candidate prostate cancer biomarkers in prostate needle biopsy specimens using proteomic analysis. Int J Cancer (2007) 1.35
Hematopoietic progenitor kinase 1 negatively regulates T cell receptor signaling and T cell-mediated immune responses. Nat Immunol (2006) 1.34
Integrative metabolic regulation of peripheral tissue fatty acid oxidation by the SRC kinase family member Fyn. Cell Metab (2007) 1.34