Published in Biometrics on June 01, 2004
Characterizing a 5P-Linked BHR Susceptibility Locus | NCT00006512
Mapping autism risk loci using genetic linkage and chromosomal rearrangements. Nat Genet (2007) 14.05
Effect of variation in CHI3L1 on serum YKL-40 level, risk of asthma, and lung function. N Engl J Med (2008) 4.58
Case-control association testing with related individuals: a more powerful quasi-likelihood score test. Am J Hum Genet (2007) 3.74
ROADTRIPS: case-control association testing with partially or completely unknown population and pedigree structure. Am J Hum Genet (2010) 2.92
Nonparametric tests of association of multiple genes with human disease. Am J Hum Genet (2005) 2.87
Testing for Hardy-Weinberg equilibrium in samples with related individuals. Genetics (2004) 1.75
Association of APOL1 variants with mild kidney disease in the first-degree relatives of African American patients with non-diabetic end-stage renal disease. Kidney Int (2012) 1.59
Genome-wide association study of plasma lipoprotein(a) levels identifies multiple genes on chromosome 6q. J Lipid Res (2009) 1.34
A genomewide search using an original pairwise sampling approach for large genealogies identifies a new locus for total and low-density lipoprotein cholesterol in two genetically differentiated isolates of Sardinia. Am J Hum Genet (2004) 1.24
An unbiased estimator of gene diversity in samples containing related individuals. Mol Biol Evol (2008) 1.18
A note on the rationale for estimating genealogical coancestry from molecular markers. Genet Sel Evol (2011) 1.14
An Incomplete-Data Quasi-likelihood Approach to Haplotype-Based Genetic Association Studies on Related Individuals. J Am Stat Assoc (2009) 1.07
Genome-wide linkage scan and association study of PARL to the expression of LHON families in Thailand. Hum Genet (2010) 0.97
MASTOR: mixed-model association mapping of quantitative traits in samples with related individuals. Am J Hum Genet (2013) 0.94
XM: association testing on the X-chromosome in case-control samples with related individuals. Genet Epidemiol (2012) 0.93
BLUP genotype imputation for case-control association testing with related individuals and missing data. J Comput Biol (2012) 0.89
Variant calling in low-coverage whole genome sequencing of a Native American population sample. BMC Genomics (2014) 0.88
Campora: a young genetic isolate in South Italy. Hum Hered (2007) 0.88
Population stratification and patterns of linkage disequilibrium. Genet Epidemiol (2009) 0.87
Pharmacogenetics in American Indian populations: analysis of CYP2D6, CYP3A4, CYP3A5, and CYP2C9 in the Confederated Salish and Kootenai Tribes. Pharmacogenet Genomics (2013) 0.86
Genetic liability to schizophrenia in Oceanic Palau: a search in the affected and maternal generation. Hum Genet (2007) 0.86
Testing for association based on excess allele sharing in a sample of related cases and controls. Hum Genet (2007) 0.85
ATRIUM: testing untyped SNPs in case-control association studies with related individuals. Am J Hum Genet (2009) 0.85
Application of a new method for GWAS in a related case/control sample with known pedigree structure: identification of new loci for nephrolithiasis. PLoS Genet (2011) 0.84
Identity-by-descent estimation and mapping of qualitative traits in large, complex pedigrees. Genetics (2008) 0.82
Quality control of genotypes using heritability estimates of gene content at the marker. Genetics (2015) 0.82
Variation in genes controlling warfarin disposition and response in American Indian and Alaska Native people: CYP2C9, VKORC1, CYP4F2, CYP4F11, GGCX. Pharmacogenet Genomics (2015) 0.81
The contribution of the functional IL6R polymorphism rs2228145, eQTLs and other genome-wide SNPs to the heritability of plasma sIL-6R levels. Behav Genet (2014) 0.81
Detecting population stratification using related individuals. BMC Proc (2009) 0.81
Efficient analysis of large datasets and sex bias with ADMIXTURE. BMC Bioinformatics (2016) 0.80
Automated SNP genotype clustering algorithm to improve data completeness in high-throughput SNP genotyping datasets from custom arrays. Genomics Proteomics Bioinformatics (2007) 0.79
Regression modeling of allele frequencies and testing Hardy Weinberg Equilibrium. Hum Hered (2013) 0.78
Family-based association analysis: a fast and efficient method of multivariate association analysis with multiple variants. BMC Bioinformatics (2015) 0.78
Efficient generalized least squares method for mixed population and family-based samples in genome-wide association studies. Genet Epidemiol (2014) 0.76
Adjusting heterogeneous ascertainment bias for genetic association analysis with extended families. BMC Med Genet (2015) 0.75
FARVATX: Family-Based Rare Variant Association Test for X-Linked Genes. Genet Epidemiol (2016) 0.75
Genotype-Based Score Test for Association Testing in Families. Stat Biosci (2015) 0.75
Family-Based Rare Variant Association Analysis: A Fast and Efficient Method of Multivariate Phenotype Association Analysis. Genet Epidemiol (2016) 0.75
An Unbiased Estimator of Gene Diversity with Improved Variance for Samples Containing Related and Inbred Individuals of any Ploidy. G3 (Bethesda) (2016) 0.75
Genetics, Diet, and Season Are Associated with Serum 25-Hydroxycholecalciferol Concentration in a Yup'ik Study Population from Southwestern Alaska. J Nutr (2015) 0.75
On the association analysis of CNV data: a fast and robust family-based association method. BMC Bioinformatics (2017) 0.75
CERAMIC: Case-Control Association Testing in Samples with Related Individuals, Based on Retrospective Mixed Model Analysis with Adjustment for Covariates. PLoS Genet (2016) 0.75
Genome-wide association study identifies a second prostate cancer susceptibility variant at 8q24. Nat Genet (2007) 19.18
A common variant associated with prostate cancer in European and African populations. Nat Genet (2006) 13.47
Two variants on chromosome 17 confer prostate cancer risk, and the one in TCF2 protects against type 2 diabetes. Nat Genet (2007) 12.65
Common sequence variants on 2p15 and Xp11.22 confer susceptibility to prostate cancer. Nat Genet (2008) 6.10
Optimal surface segmentation in volumetric images--a graph-theoretic approach. IEEE Trans Pattern Anal Mach Intell (2006) 5.58
High-resolution mapping of crossovers reveals extensive variation in fine-scale recombination patterns among humans. Science (2008) 5.02
Automated 3-D intraretinal layer segmentation of macular spectral-domain optical coherence tomography images. IEEE Trans Med Imaging (2009) 4.96
The sex-specific genetic architecture of quantitative traits in humans. Nat Genet (2006) 4.93
Paternally inherited HLA alleles are associated with women's choice of male odor. Nat Genet (2002) 3.79
Meta-analysis of genome-wide association studies of asthma in ethnically diverse North American populations. Nat Genet (2011) 3.68
Intraretinal layer segmentation of macular optical coherence tomography images using optimal 3-D graph search. IEEE Trans Med Imaging (2008) 3.68
Novel case-control test in a founder population identifies P-selectin as an atopy-susceptibility locus. Am J Hum Genet (2003) 3.62
Quantitative-trait homozygosity and association mapping and empirical genomewide significance in large, complex pedigrees: fasting serum-insulin level in the Hutterites. Am J Hum Genet (2002) 3.51
TRIM30 alpha negatively regulates TLR-mediated NF-kappa B activation by targeting TAB2 and TAB3 for degradation. Nat Immunol (2008) 3.02
Allele-specific targeting of microRNAs to HLA-G and risk of asthma. Am J Hum Genet (2007) 2.58
Genome-wide association study identifies candidate genes for male fertility traits in humans. Am J Hum Genet (2012) 2.56
Rhinovirus wheezing illness and genetic risk of childhood-onset asthma. N Engl J Med (2013) 2.53
Estimating the human mutation rate using autozygosity in a founder population. Nat Genet (2012) 2.44
HLA-G and immune tolerance in pregnancy. FASEB J (2005) 2.37
LOGISMOS--layered optimal graph image segmentation of multiple objects and surfaces: cartilage segmentation in the knee joint. IEEE Trans Med Imaging (2010) 2.14
Fine mapping and positional candidate studies identify HLA-G as an asthma susceptibility gene on chromosome 6p21. Am J Hum Genet (2004) 2.03
Evidence for extensive transmission distortion in the human genome. Am J Hum Genet (2003) 1.86
Corin gene minor allele defined by 2 missense mutations is common in blacks and associated with high blood pressure and hypertension. Circulation (2005) 1.84
Testing for Hardy-Weinberg equilibrium in samples with related individuals. Genetics (2004) 1.75
The effects of EBV transformation on gene expression levels and methylation profiles. Hum Mol Genet (2011) 1.74
Exome sequencing reveals a novel mutation for autosomal recessive non-syndromic mental retardation in the TECR gene on chromosome 19p13. Hum Mol Genet (2011) 1.70
Optimal graph search segmentation using arc-weighted graph for simultaneous surface detection of bladder and prostate. Med Image Comput Comput Assist Interv (2009) 1.69
TMEM237 is mutated in individuals with a Joubert syndrome related disorder and expands the role of the TMEM family at the ciliary transition zone. Am J Hum Genet (2011) 1.65
Incorporation of regional information in optimal 3-D graph search with application for intraretinal layer segmentation of optical coherence tomography images. Inf Process Med Imaging (2007) 1.64
Rising prevalence of asthma is sex-specific in a US farming population. J Allergy Clin Immunol (2011) 1.60
Noninvasive analysis of the sputum transcriptome discriminates clinical phenotypes of asthma. Am J Respir Crit Care Med (2015) 1.58
Treatment of early non-small cell lung cancer, stage IA, by image-guided robotic stereotactic radioablation--CyberKnife. Cancer J (2007) 1.57
Effects of dog ownership and genotype on immune development and atopy in infancy. J Allergy Clin Immunol (2004) 1.55
Peste des petits ruminants virus in Tibet, China. Emerg Infect Dis (2009) 1.54
Further replication studies of the EVE Consortium meta-analysis identifies 2 asthma risk loci in European Americans. J Allergy Clin Immunol (2012) 1.54
ECM1 controls T(H)2 cell egress from lymph nodes through re-expression of S1P(1). Nat Immunol (2011) 1.54
Nitric oxide suppresses NLRP3 inflammasome activation and protects against LPS-induced septic shock. Cell Res (2013) 1.54
Novel bunyavirus in domestic and captive farmed animals, Minnesota, USA. Emerg Infect Dis (2013) 1.53
Empirical data about women's attitudes towards a hypothetical pediatric biobank. Am J Med Genet A (2008) 1.45
Variants in DENND1A are associated with polycystic ovary syndrome in women of European ancestry. J Clin Endocrinol Metab (2012) 1.44
Heritability estimation of sex-specific effects on human quantitative traits. Genet Epidemiol (2007) 1.43
Broad-scale recombination patterns underlying proper disjunction in humans. PLoS Genet (2009) 1.42
Sequence variation in the promoter region of the cholinergic receptor muscarinic 3 gene and asthma and atopy. J Allergy Clin Immunol (2003) 1.41
Colloquium papers: Heritability of reproductive fitness traits in a human population. Proc Natl Acad Sci U S A (2009) 1.39
Association studies for asthma and atopic diseases: a comprehensive review of the literature. Respir Res (2003) 1.39
Genetic studies of stuttering in a founder population. J Fluency Disord (2006) 1.39
Optimal multiple surface segmentation with shape and context priors. IEEE Trans Med Imaging (2012) 1.38
Use of varying constraints in optimal 3-D graph search for segmentation of macular optical coherence tomography images. Med Image Comput Comput Assist Interv (2007) 1.34
Graphene oxide--MnO2 nanocomposites for supercapacitors. ACS Nano (2010) 1.34
A variant of the myosin light chain kinase gene is associated with severe asthma in African Americans. Genet Epidemiol (2007) 1.32
A genome-wide search for quantitative trait loci contributing to variation in seasonal pollen reactivity. J Allergy Clin Immunol (2006) 1.32
CyberKnife radiosurgery for stage I lung cancer: results at 36 months. Clin Lung Cancer (2007) 1.28
Evidence of balancing selection at the HLA-G promoter region. Hum Mol Genet (2005) 1.27
Evidence for gene-environment interactions in a linkage study of asthma and smoking exposure. J Allergy Clin Immunol (2003) 1.27
Sex-specific genetic architecture of whole blood serotonin levels. Am J Hum Genet (2004) 1.26
Inheritance of most X-linked traits is not dominant or recessive, just X-linked. Am J Med Genet A (2004) 1.25
A genome-wide scan for obesity in African-Americans. Diabetes (2002) 1.25
Sequencing the IL4 locus in African Americans implicates rare noncoding variants in asthma susceptibility. J Allergy Clin Immunol (2009) 1.25
The ABO blood group is a trans-species polymorphism in primates. Proc Natl Acad Sci U S A (2012) 1.23
Globally optimal tumor segmentation in PET-CT images: a graph-based co-segmentation method. Inf Process Med Imaging (2011) 1.21
Are common disease susceptibility alleles the same in outbred and founder populations? Eur J Hum Genet (2004) 1.21
Simultaneous segmentation of multiple closed surfaces using optimal graph searching. Inf Process Med Imaging (2005) 1.19
Gene-environment interaction effects on the development of immune responses in the 1st year of life. Am J Hum Genet (2005) 1.19
Tripartite-motif protein 30 negatively regulates NLRP3 inflammasome activation by modulating reactive oxygen species production. J Immunol (2010) 1.19
Present status on the genetic studies of asthma. Curr Opin Immunol (2002) 1.18
The combination of a genome-wide association study of lymphocyte count and analysis of gene expression data reveals novel asthma candidate genes. Hum Mol Genet (2012) 1.18
Suppression of the interferon and NF-κB responses by severe fever with thrombocytopenia syndrome virus. J Virol (2012) 1.17
Genetic variation in immunoregulatory pathways and atopic phenotypes in infancy. J Allergy Clin Immunol (2004) 1.17
Does HLA-dependent chimerism underlie the pathogenesis of juvenile dermatomyositis? J Immunol (2004) 1.16
Genome-wide association study identifies ITGB3 as a QTL for whole blood serotonin. Eur J Hum Genet (2004) 1.15
A genome-wide linkage and association study using COGA data. BMC Genet (2005) 1.14
Comparison of 3 reconstructive techniques in the surgical management of multilevel cervical spondylotic myelopathy. Spine (Phila Pa 1976) (2012) 1.12
Major loci influencing serum triglyceride levels on 2q14 and 9p21 localized by homozygosity-by-descent mapping in a large Hutterite pedigree. Hum Mol Genet (2003) 1.12
Genome-wide association studies of asthma indicate opposite immunopathogenesis direction from autoimmune diseases. J Allergy Clin Immunol (2012) 1.11
Variation in ITGB3 is associated with whole-blood serotonin level and autism susceptibility. Eur J Hum Genet (2006) 1.10
Resequencing candidate genes implicates rare variants in asthma susceptibility. Am J Hum Genet (2012) 1.08
Loneliness is associated with sleep fragmentation in a communal society. Sleep (2011) 1.08
Human spermatogenic failure purges deleterious mutation load from the autosomes and both sex chromosomes, including the gene DMRT1. PLoS Genet (2013) 1.08
Optimal graph search based segmentation of airway tree double surfaces across bifurcations. IEEE Trans Med Imaging (2012) 1.06
Functional variants of the sphingosine-1-phosphate receptor 1 gene associate with asthma susceptibility. J Allergy Clin Immunol (2010) 1.04
Recessive TRAPPC11 mutations cause a disease spectrum of limb girdle muscular dystrophy and myopathy with movement disorder and intellectual disability. Am J Hum Genet (2013) 1.03
Drawing the history of the Hutterite population on a genetic landscape: inference from Y-chromosome and mtDNA genotypes. Eur J Hum Genet (2009) 1.03
Aperture modulated arc therapy. Phys Med Biol (2003) 1.03
A meta-analysis of genome-wide association studies for serum total IgE in diverse study populations. J Allergy Clin Immunol (2012) 1.01
Meta-analysis of genome-wide scans for blood pressure in African American and Nigerian samples. The National Heart, Lung, and Blood Institute GeneLink Project. Am J Hypertens (2006) 1.01
A population-based study of autosomal-recessive disease-causing mutations in a founder population. Am J Hum Genet (2012) 1.00
Variation in ITGB3 is associated with asthma and sensitization to mold allergen in four populations. Am J Respir Crit Care Med (2005) 1.00
A genome-wide scan for body mass index among Nigerian families. Obes Res (2003) 0.99
Fine mapping and positional candidate studies on chromosome 5p13 identify multiple asthma susceptibility loci. J Allergy Clin Immunol (2006) 0.99
Comparative study with new accuracy metrics for target volume contouring in PET image guided radiation therapy. IEEE Trans Med Imaging (2012) 0.99
Surface-region context in optimal multi-object graph-based segmentation: robust delineation of pulmonary tumors. Inf Process Med Imaging (2011) 0.98
Linkage analysis with dense SNP maps in isolated populations. Hum Hered (2009) 0.98
Use of baculovirus expression system for generation of virus-like particles: successes and challenges. Protein Expr Purif (2013) 0.98
Detection and genetic characterization of peste des petits ruminants virus in free-living bharals (Pseudois nayaur) in Tibet, China. Res Vet Sci (2010) 0.97
Dec2 promotes Th2 cell differentiation by enhancing IL-2R signaling. J Immunol (2009) 0.97
Cytotoxic T-lymphocyte antigen-4 polymorphisms and susceptibility to osteosarcoma. DNA Cell Biol (2011) 0.97
Accurate imputation of rare and common variants in a founder population from a small number of sequenced individuals. Genet Epidemiol (2012) 0.96
Empirical data about women's attitudes toward a biobank focused on pregnancy outcomes. Am J Med Genet A (2008) 0.96
Evaluating the evidence for transmission distortion in human pedigrees. Genetics (2012) 0.96