Published in Hum Mol Genet on February 02, 2011
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Population-specificity of human DNA methylation. Genome Biol (2012) 2.04
Lymphoblastoid cell lines in pharmacogenomic discovery and clinical translation. Pharmacogenomics (2012) 1.63
Association of NCF2, IKZF1, IRF8, IFIH1, and TYK2 with systemic lupus erythematosus. PLoS Genet (2011) 1.59
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Genome-wide transcriptome profiling reveals the functional impact of rare de novo and recurrent CNVs in autism spectrum disorders. Am J Hum Genet (2012) 1.52
Methylation QTLs are associated with coordinated changes in transcription factor binding, histone modifications, and gene expression levels. PLoS Genet (2014) 1.39
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Large-scale hypomethylated blocks associated with Epstein-Barr virus-induced B-cell immortalization. Genome Res (2013) 1.34
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The combination of a genome-wide association study of lymphocyte count and analysis of gene expression data reveals novel asthma candidate genes. Hum Mol Genet (2012) 1.18
Integrating GWAS and expression data for functional characterization of disease-associated SNPs: an application to follicular lymphoma. Am J Hum Genet (2012) 1.14
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Predicting DNA methylation level across human tissues. Nucleic Acids Res (2014) 0.98
Genome-wide survey of interindividual differences of RNA stability in human lymphoblastoid cell lines. Sci Rep (2013) 0.98
Transcriptome study of differential expression in schizophrenia. Hum Mol Genet (2013) 0.97
Cellular genomics for complex traits. Nat Rev Genet (2012) 0.97
Vitamin D receptor ChIP-seq in primary CD4+ cells: relationship to serum 25-hydroxyvitamin D levels and autoimmune disease. BMC Med (2013) 0.97
Identification and validation of genetic variants that influence transcription factor and cell signaling protein levels. Am J Hum Genet (2014) 0.96
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Approaches for establishing the function of regulatory genetic variants involved in disease. Genome Med (2014) 0.87
Inter-ethnic differences in lymphocyte sensitivity to glucocorticoids reflect variation in transcriptional response. Pharmacogenomics J (2011) 0.86
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The B cell transcription program mediates hypomethylation and overexpression of key genes in Epstein-Barr virus-associated proliferative conversion. Genome Biol (2013) 0.85
Genetic and epigenetic variants contributing to clofarabine cytotoxicity. Hum Mol Genet (2013) 0.84
Statin-induced changes in gene expression in EBV-transformed and native B-cells. Hum Mol Genet (2013) 0.83
An eQTL-based method identifies CTTN and ZMAT3 as pemetrexed susceptibility markers. Hum Mol Genet (2011) 0.83
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The presence of Epstein-Barr virus significantly impacts the transcriptional profile in immunodeficiency-associated Burkitt lymphoma. Front Microbiol (2015) 0.82
The effect of freeze-thaw cycles on gene expression levels in lymphoblastoid cell lines. PLoS One (2014) 0.82
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Transcriptome outlier analysis implicates schizophrenia susceptibility genes and enriches putatively functional rare genetic variants. Hum Mol Genet (2015) 0.77
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Analysis of genome-wide RNA-sequencing data suggests age of the CEPH/Utah (CEU) lymphoblastoid cell lines systematically biases gene expression profiles. Sci Rep (2015) 0.75
Epigenome-wide cross-tissue predictive modeling and comparison of cord blood and placental methylation in a birth cohort. Epigenomics (2017) 0.75
Utility of Lymphoblastoid Cell Lines for Induced Pluripotent Stem Cell Generation. Stem Cells Int (2016) 0.75
DNA methylation-based variation between human populations. Mol Genet Genomics (2016) 0.75
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Global variation in copy number in the human genome. Nature (2006) 57.50
Population genomics of human gene expression. Nat Genet (2007) 24.49
Relative impact of nucleotide and copy number variation on gene expression phenotypes. Science (2007) 23.38
A genome-wide association study of global gene expression. Nat Genet (2007) 22.98
STRING 8--a global view on proteins and their functional interactions in 630 organisms. Nucleic Acids Res (2008) 20.62
Mapping the genetic architecture of gene expression in human liver. PLoS Biol (2008) 19.44
Mapping determinants of human gene expression by regional and genome-wide association. Nature (2005) 17.24
Understanding mechanisms underlying human gene expression variation with RNA sequencing. Nature (2010) 16.86
Common regulatory variation impacts gene expression in a cell type-dependent manner. Science (2009) 11.28
Conserved role of intragenic DNA methylation in regulating alternative promoters. Nature (2010) 9.81
High-resolution mapping of expression-QTLs yields insight into human gene regulation. PLoS Genet (2008) 9.68
Abundant quantitative trait loci exist for DNA methylation and gene expression in human brain. PLoS Genet (2010) 8.74
Sensitive, high-resolution chromatin and chromosome mapping in situ: presence and orientation of two closely integrated copies of EBV in a lymphoma line. Cell (1988) 5.16
Genetic analysis of human traits in vitro: drug response and gene expression in lymphoblastoid cell lines. PLoS Genet (2008) 5.08
Gene expression in skin and lymphoblastoid cells: Refined statistical method reveals extensive overlap in cis-eQTL signals. Am J Hum Genet (2010) 3.28
On the design and analysis of gene expression studies in human populations. Nat Genet (2007) 3.07
Identification of genetic variants contributing to cisplatin-induced cytotoxicity by use of a genomewide approach. Am J Hum Genet (2007) 3.05
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Genome-wide discovery of loci influencing chemotherapy cytotoxicity. Proc Natl Acad Sci U S A (2004) 2.37
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Radiation pharmacogenomics: a genome-wide association approach to identify radiation response biomarkers using human lymphoblastoid cell lines. Genome Res (2010) 1.87
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Mapping genes that contribute to daunorubicin-induced cytotoxicity. Cancer Res (2007) 1.73
Epstein-barr virus-induced changes in B-lymphocyte gene expression. J Virol (2002) 1.72
Epstein-barr virus transformation: involvement of latent membrane protein 1-mediated activation of NF-kappaB. Oncogene (1999) 1.69
Expression quantitative trait loci detected in cell lines are often present in primary tissues. Hum Mol Genet (2009) 1.57
Genetic variation in radiation-induced expression phenotypes. Am J Hum Genet (2004) 1.37
Comparison of the DNA methylation profiles of human peripheral blood cells and transformed B-lymphocytes. Hum Genet (2010) 1.31
Variability of gene expression profiles in human blood and lymphoblastoid cell lines. BMC Genomics (2010) 1.22
Maternal and paternal chromosomes 7 show differential methylation of many genes in lymphoblast DNA. Genomics (2001) 1.01
siRNA targeting LMP1-induced apoptosis in EBV-positive lymphoma cells is associated with inhibition of telomerase activity and expression. Cancer Lett (2006) 0.99
Posttranscriptional down-regulation of small ribosomal subunit proteins correlates with reduction of 18S rRNA in RPS19 deficiency. FEBS Lett (2009) 0.98
Pathway-selective suppression of chemokine receptor signaling in B cells by LPS through downregulation of PLC-β2. Cell Mol Immunol (2010) 0.82
[The Haplotype Map of the human genome: a revolution in the genetics of complex diseases]. Med Sci (Paris) (2006) 0.81
B-lymphoblastoid cell lines as a source of reference DNA for human platelet and neutrophil antigen genotyping. Transfusion (2000) 0.80
RNA-seq: an assessment of technical reproducibility and comparison with gene expression arrays. Genome Res (2008) 62.07
Genome-wide association study identifies a second prostate cancer susceptibility variant at 8q24. Nat Genet (2007) 19.18
Understanding mechanisms underlying human gene expression variation with RNA sequencing. Nature (2010) 16.86
A common variant associated with prostate cancer in European and African populations. Nat Genet (2006) 13.47
Two variants on chromosome 17 confer prostate cancer risk, and the one in TCF2 protects against type 2 diabetes. Nat Genet (2007) 12.65
High-resolution mapping of expression-QTLs yields insight into human gene regulation. PLoS Genet (2008) 9.68
DNA methylation patterns associate with genetic and gene expression variation in HapMap cell lines. Genome Biol (2011) 6.48
DNase I sensitivity QTLs are a major determinant of human expression variation. Nature (2012) 6.17
Common sequence variants on 2p15 and Xp11.22 confer susceptibility to prostate cancer. Nat Genet (2008) 6.10
Effect of read-mapping biases on detecting allele-specific expression from RNA-sequencing data. Bioinformatics (2009) 5.62
Accurate inference of transcription factor binding from DNA sequence and chromatin accessibility data. Genome Res (2010) 5.40
High-resolution mapping of crossovers reveals extensive variation in fine-scale recombination patterns among humans. Science (2008) 5.02
The sex-specific genetic architecture of quantitative traits in humans. Nat Genet (2006) 4.93
Sex-specific genetic architecture of human disease. Nat Rev Genet (2008) 4.01
Paternally inherited HLA alleles are associated with women's choice of male odor. Nat Genet (2002) 3.79
Meta-analysis of genome-wide association studies of asthma in ethnically diverse North American populations. Nat Genet (2011) 3.68
Novel case-control test in a founder population identifies P-selectin as an atopy-susceptibility locus. Am J Hum Genet (2003) 3.62
Sex-specific and lineage-specific alternative splicing in primates. Genome Res (2009) 3.61
Quantitative-trait homozygosity and association mapping and empirical genomewide significance in large, complex pedigrees: fasting serum-insulin level in the Hutterites. Am J Hum Genet (2002) 3.51
Noisy splicing drives mRNA isoform diversity in human cells. PLoS Genet (2010) 3.19
Identification of genetic variants that affect histone modifications in human cells. Science (2013) 3.11
Comment on "Widespread RNA and DNA sequence differences in the human transcriptome". Science (2012) 2.79
Best linear unbiased allele-frequency estimation in complex pedigrees. Biometrics (2004) 2.69
Genomics: ENCODE explained. Nature (2012) 2.62
Allele-specific targeting of microRNAs to HLA-G and risk of asthma. Am J Hum Genet (2007) 2.58
Genome-wide association study identifies candidate genes for male fertility traits in humans. Am J Hum Genet (2012) 2.56
Rhinovirus wheezing illness and genetic risk of childhood-onset asthma. N Engl J Med (2013) 2.53
Dissecting the regulatory architecture of gene expression QTLs. Genome Biol (2012) 2.51
Estimating the human mutation rate using autozygosity in a founder population. Nat Genet (2012) 2.44
HLA-G and immune tolerance in pregnancy. FASEB J (2005) 2.37
Absence of the TAP2 human recombination hotspot in chimpanzees. PLoS Biol (2004) 2.22
Primate transcript and protein expression levels evolve under compensatory selection pressures. Science (2013) 2.18
Controls of nucleosome positioning in the human genome. PLoS Genet (2012) 2.14
Different noses for different people. Nat Genet (2003) 2.10
Fine mapping and positional candidate studies identify HLA-G as an asthma susceptibility gene on chromosome 6p21. Am J Hum Genet (2004) 2.03
A genome-wide study of DNA methylation patterns and gene expression levels in multiple human and chimpanzee tissues. PLoS Genet (2011) 1.92
Gene regulation in primates evolves under tissue-specific selection pressures. PLoS Genet (2008) 1.86
Evidence for extensive transmission distortion in the human genome. Am J Hum Genet (2003) 1.86
False positive peaks in ChIP-seq and other sequencing-based functional assays caused by unannotated high copy number regions. Bioinformatics (2011) 1.85
Comparative studies of gene expression and the evolution of gene regulation. Nat Rev Genet (2012) 1.79
Testing for Hardy-Weinberg equilibrium in samples with related individuals. Genetics (2004) 1.75
Deciphering the genetic architecture of variation in the immune response to Mycobacterium tuberculosis infection. Proc Natl Acad Sci U S A (2012) 1.73
Genomic-scale capture and sequencing of endogenous DNA from feces. Mol Ecol (2010) 1.71
Exome sequencing reveals a novel mutation for autosomal recessive non-syndromic mental retardation in the TECR gene on chromosome 19p13. Hum Mol Genet (2011) 1.70
TMEM237 is mutated in individuals with a Joubert syndrome related disorder and expands the role of the TMEM family at the ciliary transition zone. Am J Hum Genet (2011) 1.65
Social environment is associated with gene regulatory variation in the rhesus macaque immune system. Proc Natl Acad Sci U S A (2012) 1.63
Rising prevalence of asthma is sex-specific in a US farming population. J Allergy Clin Immunol (2011) 1.60
Noninvasive analysis of the sputum transcriptome discriminates clinical phenotypes of asthma. Am J Respir Crit Care Med (2015) 1.58
Expression quantitative trait loci detected in cell lines are often present in primary tissues. Hum Mol Genet (2009) 1.57
Characterizing the expression of the human olfactory receptor gene family using a novel DNA microarray. Genome Biol (2007) 1.56
Effects of dog ownership and genotype on immune development and atopy in infancy. J Allergy Clin Immunol (2004) 1.55
Further replication studies of the EVE Consortium meta-analysis identifies 2 asthma risk loci in European Americans. J Allergy Clin Immunol (2012) 1.54
Using DNA microarrays to study gene expression in closely related species. Bioinformatics (2007) 1.50
Prediction of the odorant binding site of olfactory receptor proteins by human-mouse comparisons. Protein Sci (2004) 1.48
Taxonomic classification of bacterial 16S rRNA genes using short sequencing reads: evaluation of effective study designs. PLoS One (2013) 1.46
Empirical data about women's attitudes towards a hypothetical pediatric biobank. Am J Med Genet A (2008) 1.45
Evolution of bitter taste receptors in humans and apes. Mol Biol Evol (2004) 1.45
Variants in DENND1A are associated with polycystic ovary syndrome in women of European ancestry. J Clin Endocrinol Metab (2012) 1.44
Copy number variation of CCL3-like genes affects rate of progression to simian-AIDS in Rhesus Macaques (Macaca mulatta). PLoS Genet (2009) 1.43
Heritability estimation of sex-specific effects on human quantitative traits. Genet Epidemiol (2007) 1.43
Broad-scale recombination patterns underlying proper disjunction in humans. PLoS Genet (2009) 1.42
Sequence variation in the promoter region of the cholinergic receptor muscarinic 3 gene and asthma and atopy. J Allergy Clin Immunol (2003) 1.41
Colloquium papers: Heritability of reproductive fitness traits in a human population. Proc Natl Acad Sci U S A (2009) 1.39
Genetic studies of stuttering in a founder population. J Fluency Disord (2006) 1.39
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Comparative RNA sequencing reveals substantial genetic variation in endangered primates. Genome Res (2011) 1.36
A variant of the myosin light chain kinase gene is associated with severe asthma in African Americans. Genet Epidemiol (2007) 1.32
A genome-wide search for quantitative trait loci contributing to variation in seasonal pollen reactivity. J Allergy Clin Immunol (2006) 1.32
Evidence of balancing selection at the HLA-G promoter region. Hum Mol Genet (2005) 1.27
Evidence for gene-environment interactions in a linkage study of asthma and smoking exposure. J Allergy Clin Immunol (2003) 1.27
Sex-specific genetic architecture of whole blood serotonin levels. Am J Hum Genet (2004) 1.26
Inheritance of most X-linked traits is not dominant or recessive, just X-linked. Am J Med Genet A (2004) 1.25
Sequencing the IL4 locus in African Americans implicates rare noncoding variants in asthma susceptibility. J Allergy Clin Immunol (2009) 1.25
The contribution of RNA decay quantitative trait loci to inter-individual variation in steady-state gene expression levels. PLoS Genet (2012) 1.25
The ABO blood group is a trans-species polymorphism in primates. Proc Natl Acad Sci U S A (2012) 1.23
An evolutionarily conserved sexual signature in the primate brain. PLoS Genet (2008) 1.21
Are common disease susceptibility alleles the same in outbred and founder populations? Eur J Hum Genet (2004) 1.21
Gene expression differences among primates are associated with changes in a histone epigenetic modification. Genetics (2011) 1.20
Gene-environment interaction effects on the development of immune responses in the 1st year of life. Am J Hum Genet (2005) 1.19
Present status on the genetic studies of asthma. Curr Opin Immunol (2002) 1.18
The combination of a genome-wide association study of lymphocyte count and analysis of gene expression data reveals novel asthma candidate genes. Hum Mol Genet (2012) 1.18
Using reporter gene assays to identify cis regulatory differences between humans and chimpanzees. Genetics (2007) 1.18
Genetic variation in immunoregulatory pathways and atopic phenotypes in infancy. J Allergy Clin Immunol (2004) 1.17
Does HLA-dependent chimerism underlie the pathogenesis of juvenile dermatomyositis? J Immunol (2004) 1.16
Genome-wide association study identifies ITGB3 as a QTL for whole blood serotonin. Eur J Hum Genet (2004) 1.15
Major loci influencing serum triglyceride levels on 2q14 and 9p21 localized by homozygosity-by-descent mapping in a large Hutterite pedigree. Hum Mol Genet (2003) 1.12
Genome-wide association studies of asthma indicate opposite immunopathogenesis direction from autoimmune diseases. J Allergy Clin Immunol (2012) 1.11
Variation in ITGB3 is associated with whole-blood serotonin level and autism susceptibility. Eur J Hum Genet (2006) 1.10
Functional comparison of innate immune signaling pathways in primates. PLoS Genet (2010) 1.09
A combination of genomic approaches reveals the role of FOXO1a in regulating an oxidative stress response pathway. PLoS One (2008) 1.08
Resequencing candidate genes implicates rare variants in asthma susceptibility. Am J Hum Genet (2012) 1.08
Loneliness is associated with sleep fragmentation in a communal society. Sleep (2011) 1.08
Human spermatogenic failure purges deleterious mutation load from the autosomes and both sex chromosomes, including the gene DMRT1. PLoS Genet (2013) 1.08
A genome sequence resource for the aye-aye (Daubentonia madagascariensis), a nocturnal lemur from Madagascar. Genome Biol Evol (2011) 1.07
Segmental duplications contribute to gene expression differences between humans and chimpanzees. Genetics (2009) 1.06
Functional variants of the sphingosine-1-phosphate receptor 1 gene associate with asthma susceptibility. J Allergy Clin Immunol (2010) 1.04
Recessive TRAPPC11 mutations cause a disease spectrum of limb girdle muscular dystrophy and myopathy with movement disorder and intellectual disability. Am J Hum Genet (2013) 1.03
Drawing the history of the Hutterite population on a genetic landscape: inference from Y-chromosome and mtDNA genotypes. Eur J Hum Genet (2009) 1.03