|
1
|
C-reactive protein and other circulating markers of inflammation in the prediction of coronary heart disease.
|
N Engl J Med
|
2004
|
15.30
|
|
2
|
C-reactive protein, fibrinogen, and cardiovascular disease prediction.
|
N Engl J Med
|
2012
|
6.39
|
|
3
|
Plasma fibrinogen level and the risk of major cardiovascular diseases and nonvascular mortality: an individual participant meta-analysis.
|
JAMA
|
2005
|
5.60
|
|
4
|
C-reactive protein and its role in metabolic syndrome: mendelian randomisation study.
|
Lancet
|
2005
|
5.51
|
|
5
|
Aspirin for prevention of cardiovascular events in a general population screened for a low ankle brachial index: a randomized controlled trial.
|
JAMA
|
2010
|
5.10
|
|
6
|
Long-term interleukin-6 levels and subsequent risk of coronary heart disease: two new prospective studies and a systematic review.
|
PLoS Med
|
2008
|
4.34
|
|
7
|
C-reactive protein is an independent predictor of risk for the development of diabetes in the West of Scotland Coronary Prevention Study.
|
Diabetes
|
2002
|
3.59
|
|
8
|
Physical activity and hemostatic and inflammatory variables in elderly men.
|
Circulation
|
2002
|
2.75
|
|
9
|
Seven haemostatic gene polymorphisms in coronary disease: meta-analysis of 66,155 cases and 91,307 controls.
|
Lancet
|
2006
|
2.72
|
|
10
|
C-reactive protein, interleukin-6, and soluble adhesion molecules as predictors of progressive peripheral atherosclerosis in the general population: Edinburgh Artery Study.
|
Circulation
|
2005
|
2.53
|
|
11
|
Association of C-reactive protein with blood pressure and hypertension: life course confounding and mendelian randomization tests of causality.
|
Arterioscler Thromb Vasc Biol
|
2005
|
2.42
|
|
12
|
Associations of vitamin C status, fruit and vegetable intakes, and markers of inflammation and hemostasis.
|
Am J Clin Nutr
|
2006
|
2.24
|
|
13
|
Associations between cigarette smoking, pipe/cigar smoking, and smoking cessation, and haemostatic and inflammatory markers for cardiovascular disease.
|
Eur Heart J
|
2005
|
2.21
|
|
14
|
Lipoprotein(a) levels and risk of future coronary heart disease: large-scale prospective data.
|
Arch Intern Med
|
2008
|
2.01
|
|
15
|
Inflammation, insulin resistance, and diabetes--Mendelian randomization using CRP haplotypes points upstream.
|
PLoS Med
|
2008
|
1.95
|
|
16
|
Relative value of inflammatory, hemostatic, and rheological factors for incident myocardial infarction and stroke: the Edinburgh Artery Study.
|
Circulation
|
2007
|
1.85
|
|
17
|
Hormone replacement therapy and risk of venous thromboembolism in postmenopausal women: systematic review and meta-analysis.
|
BMJ
|
2008
|
1.78
|
|
18
|
Gender differences in the cross-sectional relationships between sleep duration and markers of inflammation: Whitehall II study.
|
Sleep
|
2009
|
1.77
|
|
19
|
Adipokines and risk of type 2 diabetes in older men.
|
Diabetes Care
|
2007
|
1.63
|
|
20
|
D-dimer predicts early clinical progression in ischemic stroke: confirmation using routine clinical assays.
|
Stroke
|
2006
|
1.60
|
|
21
|
Adipocytokines and risk of stroke in older people: a nested case-control study.
|
Int J Epidemiol
|
2008
|
1.59
|
|
22
|
Inflammatory cytokines and risk of coronary heart disease: new prospective study and updated meta-analysis.
|
Eur Heart J
|
2013
|
1.53
|
|
23
|
Extent of regression dilution for established and novel coronary risk factors: results from the British Regional Heart Study.
|
Eur J Cardiovasc Prev Rehabil
|
2004
|
1.47
|
|
24
|
Diurnal, seasonal, and blood-processing patterns in levels of circulating fibrinogen, fibrin D-dimer, C-reactive protein, tissue plasminogen activator, and von Willebrand factor in a 45-year-old population.
|
Circulation
|
2007
|
1.47
|
|
25
|
Inflammatory, haemostatic, and rheological markers for incident peripheral arterial disease: Edinburgh Artery Study.
|
Eur Heart J
|
2007
|
1.47
|
|
26
|
Cognitive decline and markers of inflammation and hemostasis: the Edinburgh Artery Study.
|
J Am Geriatr Soc
|
2007
|
1.46
|
|
27
|
Association of novel genetic Loci with circulating fibrinogen levels: a genome-wide association study in 6 population-based cohorts.
|
Circ Cardiovasc Genet
|
2009
|
1.41
|
|
28
|
Association between raised inflammatory markers and cognitive decline in elderly people with type 2 diabetes: the Edinburgh Type 2 Diabetes Study.
|
Diabetes
|
2009
|
1.34
|
|
29
|
Plasma leptin: associations with metabolic, inflammatory and haemostatic risk factors for cardiovascular disease.
|
Atherosclerosis
|
2006
|
1.29
|
|
30
|
Associations of fibrinogen and C-reactive protein with prevalent and incident coronary heart disease are attenuated by adjustment for confounding factors. British Women's Heart and Health Study.
|
Thromb Haemost
|
2005
|
1.29
|
|
31
|
The association of C-reactive protein and CRP genotype with coronary heart disease: findings from five studies with 4,610 cases amongst 18,637 participants.
|
PLoS One
|
2008
|
1.28
|
|
32
|
Guidelines on fibrinogen assays.
|
Br J Haematol
|
2003
|
1.23
|
|
33
|
Associations of inflammatory and haemostatic biomarkers with poor outcome in acute ischaemic stroke.
|
Cerebrovasc Dis
|
2009
|
1.21
|
|
34
|
Adult socioeconomic position, C-reactive protein and interleukin-6 in the Whitehall II prospective study.
|
Eur J Epidemiol
|
2007
|
1.21
|
|
35
|
Associations of proinflammatory cytokines with the risk of recurrent stroke.
|
Stroke
|
2008
|
1.17
|
|
36
|
Randomized controlled trial of homocysteine-lowering vitamin treatment in elderly patients with vascular disease.
|
Am J Clin Nutr
|
2005
|
1.17
|
|
37
|
The metabolic syndrome and insulin resistance: relationship to haemostatic and inflammatory markers in older non-diabetic men.
|
Atherosclerosis
|
2005
|
1.13
|
|
38
|
Interleukin-6 -174G>C polymorphism and risk of coronary heart disease in West of Scotland coronary prevention study (WOSCOPS).
|
Arterioscler Thromb Vasc Biol
|
2002
|
1.12
|
|
39
|
Influence of socioeconomic status and job control on plasma fibrinogen responses to acute mental stress.
|
Psychosom Med
|
2003
|
1.12
|
|
40
|
Endothelial dysfunction and inflammation in asymptomatic proteinuria.
|
Kidney Int
|
2003
|
1.10
|
|
41
|
C-reactive protein: associations with haematological variables, cardiovascular risk factors and prevalent cardiovascular disease.
|
Br J Haematol
|
2003
|
1.09
|
|
42
|
Associations of inflammatory and hemostatic variables with the risk of recurrent stroke.
|
Stroke
|
2005
|
1.07
|
|
43
|
Peripheral levels of fibrinogen, C-reactive protein, and plasma viscosity predict future cognitive decline in individuals without dementia.
|
Psychosom Med
|
2009
|
1.07
|
|
44
|
The associations of interleukin-6 (IL-6) and downstream inflammatory markers with risk of cardiovascular disease: the Caerphilly Study.
|
Atherosclerosis
|
2009
|
1.07
|
|
45
|
Cardiovascular risk parameters in men with ankylosing spondylitis in comparison with non-inflammatory control subjects: relevance of systemic inflammation.
|
Clin Sci (Lond)
|
2005
|
1.06
|
|
46
|
Genetic associations for activated partial thromboplastin time and prothrombin time, their gene expression profiles, and risk of coronary artery disease.
|
Am J Hum Genet
|
2012
|
1.05
|
|
47
|
Renal function and cardiovascular mortality in elderly men: the role of inflammatory, procoagulant, and endothelial biomarkers.
|
Eur Heart J
|
2006
|
1.05
|
|
48
|
Hemostatic function and progressing ischemic stroke: D-dimer predicts early clinical progression.
|
Stroke
|
2004
|
1.05
|
|
49
|
Genetic predictors of fibrin D-dimer levels in healthy adults.
|
Circulation
|
2011
|
1.05
|
|
50
|
Oral contraceptives, hormone replacement therapy, thrombophilias and risk of venous thromboembolism: a systematic review. The Thrombosis: Risk and Economic Assessment of Thrombophilia Screening (TREATS) Study.
|
Thromb Haemost
|
2005
|
1.01
|
|
51
|
Association of the factor XII 46C>T polymorphism with risk of coronary heart disease (CHD) in the WOSCOPS study.
|
Atherosclerosis
|
2002
|
0.99
|
|
52
|
Relationships of inflammatory and haemostatic markers with social class: results from a population-based study of older men.
|
Atherosclerosis
|
2007
|
0.99
|
|
53
|
Interleukin 18 and coronary heart disease: prospective study and systematic review.
|
Atherosclerosis
|
2011
|
0.98
|
|
54
|
Tissue plasminogen activator, von Willebrand factor, and risk of type 2 diabetes in older men.
|
Diabetes Care
|
2008
|
0.97
|
|
55
|
Childhood intelligence and midlife inflammatory and hemostatic biomarkers: the National Child Development Study (1958) cohort.
|
Health Psychol
|
2011
|
0.95
|
|
56
|
Hemostatic factors, inflammatory markers, and progressive peripheral atherosclerosis: the Edinburgh Artery Study.
|
Am J Epidemiol
|
2005
|
0.94
|
|
57
|
Association between plasma IL-6, the IL6 -174G>C gene variant and the metabolic syndrome in type 2 diabetes mellitus.
|
Mol Genet Metab
|
2006
|
0.92
|
|
58
|
Prolonged elevations in haemostatic and rheological responses following psychological stress in low socioeconomic status men and women.
|
Thromb Haemost
|
2003
|
0.92
|
|
59
|
Do inflammatory biomarkers add to the discrimination of cardiovascular disease after allowing for social deprivation? Results from a 10-year cohort study in Glasgow, Scotland.
|
Eur Heart J
|
2009
|
0.90
|
|
60
|
Distributions of C-reactive protein measured by high-sensitivity assays in apparently healthy men and women from different populations in Europe.
|
Clin Chem
|
2003
|
0.90
|
|
61
|
Genetic variants associated with altered plasma levels of C-reactive protein are not associated with late-life cognitive ability in four Scottish samples.
|
Behav Genet
|
2009
|
0.90
|
|
62
|
Reduced lung function in patients with abdominal aortic aneurysm is associated with activation of inflammation and hemostasis, not smoking or cardiovascular disease.
|
J Vasc Surg
|
2006
|
0.89
|
|
63
|
Metabolic syndrome, haemostatic and inflammatory markers, cerebrovascular and peripheral arterial disease: The Edinburgh Artery Study.
|
Atherosclerosis
|
2008
|
0.88
|
|
64
|
The association between homocysteine and myocardial infarction is independent of age, sex, blood pressure, cholesterol, smoking and markers of inflammation: the Glasgow Myocardial Infarction Study.
|
Blood Coagul Fibrinolysis
|
2006
|
0.88
|
|
65
|
Activation of hemostasis and decline in cognitive function in older people.
|
Arterioscler Thromb Vasc Biol
|
2009
|
0.87
|
|
66
|
Inflammation and not cardiovascular risk factors is associated with short leukocyte telomere length in 13- to 16-year-old adolescents.
|
Arterioscler Thromb Vasc Biol
|
2012
|
0.86
|
|
67
|
Does sticky blood predict a sticky end? Associations of blood viscosity, haematocrit and fibrinogen with mortality in the West of Scotland.
|
Br J Haematol
|
2003
|
0.85
|
|
68
|
Circulating TNFalpha levels in older men and women do not show independent prospective relations with MI or stroke.
|
Atherosclerosis
|
2008
|
0.85
|
|
69
|
Higher IL-6 levels but not IL6 -174G>C or -572G>C genotype are associated with post-operative complication following coronary artery bypass graft (CABG) surgery.
|
Atherosclerosis
|
2008
|
0.84
|
|
70
|
The effects of different alcoholic drinks on lipids, insulin and haemostatic and inflammatory markers in older men.
|
Thromb Haemost
|
2003
|
0.83
|
|
71
|
A specific elevation in tissue plasminogen activator antigen in women with polycystic ovarian syndrome.
|
J Clin Endocrinol Metab
|
2002
|
0.83
|
|
72
|
Body fat distribution in relation to smoking and exogenous hormones in British women.
|
Clin Endocrinol (Oxf)
|
2012
|
0.82
|
|
73
|
A gene-centric analysis of activated partial thromboplastin time and activated protein C resistance using the HumanCVD focused genotyping array.
|
Eur J Hum Genet
|
2012
|
0.82
|
|
74
|
Vascular dysfunction and alteration of novel and classic cardiovascular risk factors in mothers of growth restricted offspring.
|
Atherosclerosis
|
2008
|
0.81
|
|
75
|
Genetic associations between fibrinogen and cognitive performance in three Scottish cohorts.
|
Behav Genet
|
2011
|
0.81
|
|
76
|
Does fibrinogen add to prediction of cardiovascular disease? Results from the Scottish Heart Health Extended Cohort Study.
|
Br J Haematol
|
2009
|
0.81
|
|
77
|
Increased C-reactive protein levels in overweight and obese women taking exogenous hormones: the United Kingdom Women's Heart Study (UKWHS).
|
Clin Endocrinol (Oxf)
|
2009
|
0.80
|
|
78
|
Angina and intermittent claudication in 7403 participants of the 2003 Scottish Health Survey: impact on general and mental health, quality of life and five-year mortality.
|
Int J Cardiol
|
2012
|
0.79
|
|
79
|
Relationship of the platelet glycoprotein PlA and fibrinogen T/G+1689 polymorphisms with peripheral arterial disease and ischaemic heart disease.
|
Thromb Res
|
2003
|
0.79
|
|
80
|
Tissue plasminogen activator antigen predicts medium-term left ventricular end-systolic volume after acute myocardial infarction.
|
J Thromb Thrombolysis
|
2010
|
0.78
|
|
81
|
Incident venous thromboembolic events in the Prospective Study of Pravastatin in the Elderly at Risk (PROSPER).
|
BMC Geriatr
|
2011
|
0.78
|
|
82
|
Prospective study of IL-18 and risk of MI and stroke in men and women aged 60-79 years: a nested case-control study.
|
Cytokine
|
2012
|
0.78
|
|
83
|
Direct comparisons of three alternative plasma fibrinogen assays with the von Clauss assay in prediction of cardiovascular disease and all-causes mortality: the Scottish Heart Health Extended Cohort.
|
Br J Haematol
|
2013
|
0.77
|
|
84
|
Low-intensity warfarin reduces thrombin generation and fibrin turnover, but not low-grade inflammation, in men at risk of myocardial infarction.
|
Br J Haematol
|
2004
|
0.77
|
|
85
|
Indices of obesity and cardiovascular risk factors in British women.
|
Obes Facts
|
2008
|
0.77
|
|
86
|
Fibrinogen assays for cardiovascular risk assessment.
|
Clin Chem
|
2010
|
0.77
|
|
87
|
Successful elimination of factor VIII inhibitor using cyclosporin A.
|
Br J Haematol
|
2003
|
0.76
|
|
88
|
Resonance-thrombography indices of the haemostatic process in relation to risk of incident coronary heart disease: 9 years follow-up in the Caerphilly Prospective Heart Disease Study.
|
Br J Haematol
|
2004
|
0.76
|
|
89
|
Plasma Biomarkers of Inflammation, Endothelial Function and Hemostasis in Cerebral Small Vessel Disease.
|
Cerebrovasc Dis
|
2015
|
0.76
|
|
90
|
Britain's failure to tackle research misconduct: UK bodies are now working together to set up panel on misconduct.
|
BMJ
|
2004
|
0.75
|
|
91
|
Glucocorticoid treatment and impaired mood, memory and metabolism in people with diabetes: the Edinburgh Type 2 Diabetes Study.
|
Eur J Endocrinol
|
2012
|
0.75
|
|
92
|
The association between blood coagulation activity and lung function: a population-based study.
|
PLoS One
|
2010
|
0.75
|
|
93
|
Our inability to predict thromboembolic events after prosthetic valve surgery.
|
J Heart Valve Dis
|
2006
|
0.75
|
|
94
|
Venous thrombosis prevention - more than just guidelines.
|
Br J Haematol
|
2010
|
0.75
|
|
95
|
Genome-wide association studies identify genetic loci for low von Willebrand factor levels.
|
Eur J Hum Genet
|
2016
|
0.75
|
|
96
|
On the route to combined evidence from OC and HRT/ERT.
|
Eur J Contracept Reprod Health Care
|
2002
|
0.75
|