Published in J Neurosci on June 09, 2004
5-HT(1A) receptor function in major depressive disorder. Prog Neurobiol (2009) 1.99
Serotonin-1A autoreceptor binding in the dorsal raphe nucleus of depressed suicides. J Psychiatr Res (2007) 1.40
Measuring endogenous 5-HT release by emission tomography: promises and pitfalls. J Cereb Blood Flow Metab (2010) 1.16
Transcriptional regulation of the 5-HT1A receptor: implications for mental illness. Philos Trans R Soc Lond B Biol Sci (2012) 1.10
Deficient serotonin neurotransmission and depression-like serotonin biomarker alterations in tryptophan hydroxylase 2 (Tph2) loss-of-function mice. Mol Psychiatry (2011) 1.10
Exercise, stress resistance, and central serotonergic systems. Exerc Sport Sci Rev (2011) 1.05
Effects of the antidepressant fluoxetine on the subcellular localization of 5-HT1A receptors and SERT. Philos Trans R Soc Lond B Biol Sci (2012) 1.04
The response of neurons in the bed nucleus of the stria terminalis to serotonin: implications for anxiety. Prog Neuropsychopharmacol Biol Psychiatry (2009) 1.03
Activation of 5-HT1A autoreceptors in the dorsal raphe nucleus reduces the behavioral consequences of social defeat. Psychoneuroendocrinology (2008) 1.00
Transcriptional dysregulation of 5-HT1A autoreceptors in mental illness. Mol Brain (2011) 0.99
Uncontrollable, but not controllable, stress desensitizes 5-HT1A receptors in the dorsal raphe nucleus. J Neurosci (2011) 0.97
Anxiety-like behaviors produced by acute fluoxetine administration in male Fischer 344 rats are prevented by prior exercise. Psychopharmacology (Berl) (2008) 0.91
Modifying 5-HT1A Receptor Gene Expression as a New Target for Antidepressant Therapy. Front Neurosci (2010) 0.90
The neurobiology of depression--revisiting the serotonin hypothesis. II. Genetic, epigenetic and clinical studies. Philos Trans R Soc Lond B Biol Sci (2013) 0.86
Fluoxetine treatment ameliorates depression induced by perinatal arsenic exposure via a neurogenic mechanism. Neurotoxicology (2014) 0.86
GABAergic control of depression-related brain states. Adv Pharmacol (2015) 0.86
Synthesis and in vivo evaluation of [(18)F]2-(4-(4-(2-(2-fluoroethoxy)phenyl)piperazin-1-yl)butyl)-4-methyl-1,2,4-triazine-3,5(2H,4H)-dione ([(18)F]FECUMI-101) as an imaging probe for 5-HT1A receptor agonist in nonhuman primates. Bioorg Med Chem (2013) 0.84
Subanesthetic doses of ketamine transiently decrease serotonin transporter activity: a PET study in conscious monkeys. Neuropsychopharmacology (2013) 0.82
Small animal PET imaging of the type 1 cannabinoid receptor in a rodent model for anorexia nervosa. Eur J Nucl Med Mol Imaging (2013) 0.80
MicroPET imaging of 5-HT 1A receptors in rat brain: a test-retest [18F]MPPF study. Eur J Nucl Med Mol Imaging (2008) 0.79
Application of cross-species PET imaging to assess neurotransmitter release in brain. Psychopharmacology (Berl) (2015) 0.79
Facilitation of serotonin signaling by SSRIs is attenuated by social isolation. Neuropsychopharmacology (2014) 0.77
Functional Selectivity and Antidepressant Activity of Serotonin 1A Receptor Ligands. Int J Mol Sci (2015) 0.76
Acute selective serotonin reuptake inhibitors regulate the dorsal raphe nucleus causing amplification of terminal serotonin release. J Neurochem (2016) 0.76
Possible involvement of the JAK/STAT signaling pathway in N-acetylcysteine-mediated antidepressant-like effects. Exp Biol Med (Maywood) (2015) 0.75
Voltammetric and mathematical evidence for dual transport mediation of serotonin clearance in vivo. J Neurochem (2014) 0.75
5-Hydroxytryptamine (5-HT) cellular sequestration during chronic exposure delays 5-HT3 receptor resensitization due to its subsequent release. J Biol Chem (2014) 0.75
Modulation of defensive reflex conditioning in snails by serotonin. Front Behav Neurosci (2015) 0.75
Effects of serotonin on erythropoietin expression in mouse hippocampus. Exp Neurobiol (2013) 0.75
Molecular imaging of individual behaviour. Eur J Nucl Med Mol Imaging (2005) 0.75
Antidepressant-like activity of flunarizine in modified tail suspension test in rats. N Am J Med Sci (2015) 0.75
Association between cerebral cannabinoid 1 receptor availability and body mass index in patients with food intake disorders and healthy subjects: a [(18)F]MK-9470 PET study. Transl Psychiatry (2016) 0.75
Disruption of the nonneuronal tph1 gene demonstrates the importance of peripheral serotonin in cardiac function. Proc Natl Acad Sci U S A (2003) 2.19
Transgenic mice overexpressing the 5-hydroxytryptamine transporter gene in smooth muscle develop pulmonary hypertension. Circ Res (2006) 2.10
Serotonin-induced smooth muscle hyperplasia in various forms of human pulmonary hypertension. Circ Res (2004) 1.92
Maladaptive plasticity of serotonin axon terminals in levodopa-induced dyskinesia. Ann Neurol (2010) 1.80
From glutamate co-release to vesicular synergy: vesicular glutamate transporters. Nat Rev Neurosci (2011) 1.79
Cross talk between endothelial and smooth muscle cells in pulmonary hypertension: critical role for serotonin-induced smooth muscle hyperplasia. Circulation (2006) 1.79
Mice lacking brain/kidney phosphate-activated glutaminase have impaired glutamatergic synaptic transmission, altered breathing, disorganized goal-directed behavior and die shortly after birth. J Neurosci (2006) 1.55
The dual dopamine-glutamate phenotype of growing mesencephalic neurons regresses in mature rat brain. J Comp Neurol (2009) 1.55
Corticosteroid-serotonin interactions in the neurobiological mechanisms of stress-related disorders. Neurosci Biobehav Rev (2008) 1.50
Behavioral, neurochemical, and electrophysiological characterization of a genetic mouse model of depression. Proc Natl Acad Sci U S A (2003) 1.48
Serotonin transporter inhibition prevents and reverses monocrotaline-induced pulmonary hypertension in rats. Circulation (2005) 1.40
Localization of EphA4 in axon terminals and dendritic spines of adult rat hippocampus. J Comp Neurol (2007) 1.34
Polymorphism of the serotonin transporter gene and pulmonary hypertension in chronic obstructive pulmonary disease. Circulation (2003) 1.34
VGLUT3 (vesicular glutamate transporter type 3) contribution to the regulation of serotonergic transmission and anxiety. J Neurosci (2010) 1.29
Angiopoietin/Tie2 pathway influences smooth muscle hyperplasia in idiopathic pulmonary hypertension. Am J Respir Crit Care Med (2006) 1.29
Direct Immunohistochemical Evidence of the Existence of 5-HT1A Autoreceptors on Serotoninergic Neurons in the Midbrain Raphe Nuclei. Eur J Neurosci (1990) 1.21
Attenuation of pain-related behavior in a rat model of trigeminal neuropathic pain by viral-driven enkephalin overproduction in trigeminal ganglion neurons. Mol Ther (2005) 1.14
3,4-methylenedioxymethamphetamine self-administration is abolished in serotonin transporter knockout mice. Biol Psychiatry (2007) 1.14
A 18F-MPPF PET normative database of 5-HT1A receptor binding in men and women over aging. J Nucl Med (2005) 1.13
Cannabinoid CB1 receptors are involved in motivational effects of nicotine in rats. Psychopharmacology (Berl) (2005) 1.12
The antimigraine 5-HT 1B/1D receptor agonists, sumatriptan, zolmitriptan and dihydroergotamine, attenuate pain-related behaviour in a rat model of trigeminal neuropathic pain. Br J Pharmacol (2002) 1.10
Small-animal positron emission tomography as a tool for neuropharmacology. Trends Pharmacol Sci (2010) 1.10
Activation of afferents to the ventral tegmental area in response to acute amphetamine: a double-labelling study. Eur J Neurosci (2007) 1.08
Serotonin transporter inhibitors protect against hypoxic pulmonary hypertension. Am J Respir Crit Care Med (2003) 1.08
5-HT7 receptor activation inhibits mechanical hypersensitivity secondary to capsaicin sensitization in mice. Pain (2008) 1.07
Microglial glucocorticoid receptors play a pivotal role in regulating dopaminergic neurodegeneration in parkinsonism. Proc Natl Acad Sci U S A (2011) 1.07
Lentiviral-mediated targeted NF-kappaB blockade in dorsal spinal cord glia attenuates sciatic nerve injury-induced neuropathic pain in the rat. Mol Ther (2007) 1.04
Enhanced sucrose and cocaine self-administration and cue-induced drug seeking after loss of VGLUT2 in midbrain dopamine neurons in mice. J Neurosci (2011) 1.04
Severe serotonin depletion after conditional deletion of the vesicular monoamine transporter 2 gene in serotonin neurons: neural and behavioral consequences. Neuropsychopharmacology (2011) 1.03
Glutamate corelease promotes growth and survival of midbrain dopamine neurons. J Neurosci (2012) 1.03
Role of the C-terminal di-leucine motif of 5-HT1A and 5-HT1B serotonin receptors in plasma membrane targeting. J Cell Sci (2006) 1.02
Impacts of brain serotonin deficiency following Tph2 inactivation on development and raphe neuron serotonergic specification. PLoS One (2012) 1.02
Neurochemical and behavioral alterations in glucocorticoid receptor-impaired transgenic mice after chronic mild stress. J Neurosci (2004) 1.02
TrkB inhibition as a therapeutic target for CNS-related disorders. Prog Neurobiol (2012) 1.02
Early life blockade of 5-hydroxytryptamine 1A receptors normalizes sleep and depression-like behavior in adult knock-out mice lacking the serotonin transporter. J Neurosci (2006) 1.01
Brain-derived neurotrophic factor-deficient mice exhibit a hippocampal hyperserotonergic phenotype. Int J Neuropsychopharmacol (2007) 1.01
Behavioural and neuroplastic effects of the new-generation antidepressant agomelatine compared to fluoxetine in glucocorticoid receptor-impaired mice. Int J Neuropsychopharmacol (2009) 1.01
Microtubule-associated STOP protein deletion triggers restricted changes in dopaminergic neurotransmission. J Neurochem (2008) 1.00
Differential implication of proinflammatory cytokine interleukin-6 in the development of cephalic versus extracephalic neuropathic pain in rats. J Neurosci (2008) 1.00
Targeting of the 5-HT1A serotonin receptor to neuronal dendrites is mediated by Yif1B. J Neurosci (2008) 1.00
Contribution of 5-HT2 receptor subtypes to sleep-wakefulness and respiratory control, and functional adaptations in knock-out mice lacking 5-HT2A receptors. J Neurosci (2005) 1.00
Is the serotonin transporter involved in the pathogenesis of pulmonary hypertension? J Lab Clin Med (2002) 0.99
5-HT1 receptors. Curr Drug Targets CNS Neurol Disord (2004) 0.99
Sex hormone-dependent desensitization of 5-HT1A autoreceptors in knockout mice deficient in the 5-HT transporter. Eur J Neurosci (2003) 0.99
The CNR1 gene as a pharmacogenetic factor for antipsychotics rather than a susceptibility gene for schizophrenia. Eur Neuropsychopharmacol (2007) 0.98
The 3' region of the DRD2 gene is involved in genetic susceptibility to schizophrenia. Schizophr Res (2004) 0.98
Hippocampal neurogenesis, depressive disorders, and antidepressant therapy. Neural Plast (2007) 0.98
Regional differences in the coupling of 5-hydroxytryptamine-1A receptors to G proteins in the rat brain. Mol Pharmacol (2006) 0.97
The deletion of STOP/MAP6 protein in mice triggers highly altered mood and impaired cognitive performances. J Neurochem (2012) 0.97
Acetylcholine innervation of the adult rat thalamus: distribution and ultrastructural features in dorsolateral geniculate, parafascicular, and reticular thalamic nuclei. J Comp Neurol (2008) 0.97
Life-long hippocampal neurogenesis: environmental, pharmacological and neurochemical modulations. Neurochem Res (2007) 0.97
Chloramphenicol decreases brain glucose utilization and modifies the sleep-wake cycle architecture in rats. J Neurochem (2005) 0.96
The deletion of the microtubule-associated STOP protein affects the serotonergic mouse brain network. J Neurochem (2010) 0.96
Ultrastructural features of the acetylcholine innervation in the developing parietal cortex of rat. J Comp Neurol (2002) 0.96
Parkin deficiency delays motor decline and disease manifestation in a mouse model of synucleinopathy. PLoS One (2009) 0.95
Postnatal development of the cholinergic innervation in the dorsal hippocampus of rat: Quantitative light and electron microscopic immunocytochemical study. J Comp Neurol (2005) 0.95
Effects of a dopamine D3 receptor ligand, BP 897, on acquisition and expression of food-, morphine-, and cocaine-induced conditioned place preference, and food-seeking behavior in rats. Neuropsychopharmacology (2003) 0.93
Ultrastructural characterization of the mesostriatal dopamine innervation in mice, including two mouse lines of conditional VGLUT2 knockout in dopamine neurons. Eur J Neurosci (2012) 0.93
Involvement of 5-HT1A receptors in homeostatic and stress-induced adaptive regulations of paradoxical sleep: studies in 5-HT1A knock-out mice. J Neurosci (2002) 0.93
The A9 allele of the dopamine transporter gene is associated with delirium tremens and alcohol-withdrawal seizure. Biol Psychiatry (2003) 0.92
5-HT7 receptor antagonists as a new class of antidepressants. Drug News Perspect (2007) 0.92
Single intranasal administration of 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine in C57BL/6 mice models early preclinical phase of Parkinson's disease. Neurotox Res (2009) 0.92
Heterogeneous distribution of the serotonin 5-HT(1A) receptor mRNA in chemically identified neurons of the mouse rostral brainstem: Implications for the role of serotonin in the regulation of wakefulness and REM sleep. J Comp Neurol (2010) 0.92
Blockade of beta 1- and desensitization of beta 2-adrenoceptors reduce isoprenaline-induced cardiac fibrosis. Eur J Pharmacol (2004) 0.91
The neurobiology of depression--revisiting the serotonin hypothesis. I. Cellular and molecular mechanisms. Philos Trans R Soc Lond B Biol Sci (2012) 0.91
Novel potent 5-HT(3) receptor ligands based on the pyrrolidone structure: synthesis, biological evaluation, and computational rationalization of the ligand-receptor interaction modalities. Bioorg Med Chem (2002) 0.91
Multiple roles of serotonin in pain control mechanisms--implications of 5-HT₇ and other 5-HT receptor types. Eur J Pharmacol (2013) 0.90
Promotion of non-rapid eye movement sleep and activation of reticular thalamic neurons by a novel MT2 melatonin receptor ligand. J Neurosci (2011) 0.89
Immunolabelling of the 5-HT 3B receptor subunit in the central and peripheral nervous systems in rodents. Eur J Neurosci (2007) 0.89
A comparison of in vivo and in vitro neuroimaging of 5-HT 1A receptor binding sites in the cat brain. J Chem Neuroanat (2006) 0.89
Lack of CB1 receptor activity impairs serotonergic negative feedback. J Neurochem (2009) 0.89
Pharmacological activation of 5-HT7 receptors reduces nerve injury-induced mechanical and thermal hypersensitivity. Pain (2010) 0.89
5-HT2C receptor activation prevents stress-induced enhancement of brain 5-HT turnover and extracellular levels in the mouse brain: modulation by chronic paroxetine treatment. J Neurochem (2010) 0.89
Combining the radiosensitive Beta MicroProbe to nuclear magnetic resonance: theoretical approach for in vivo studies in small animals. J Neurosci Methods (2004) 0.87
Cholinergic innervation and thalamic input in rat nucleus accumbens. J Chem Neuroanat (2008) 0.87
A haplotype of the norepinephrine transporter (Net) gene Slc6a2 is associated with clinical response to atomoxetine in attention-deficit hyperactivity disorder (ADHD). Neuropsychopharmacology (2009) 0.87
5-HT 1A/1B receptor-mediated effects of the selective serotonin reuptake inhibitor, citalopram, on sleep: studies in 5-HT 1A and 5-HT 1B knockout mice. Neuropsychopharmacology (2003) 0.87
Enhanced anxiety observed in cocaine withdrawn rats is associated with altered reactivity of the dorsomedial prefrontal cortex. PLoS One (2012) 0.86
Alcohol intake after serotonin transporter inactivation in mice. Alcohol Alcohol (2003) 0.86
Immunocytochemical evidence for the existence of substance P receptor (NK1) in serotonin neurons of rat and mouse dorsal raphe nucleus. Eur J Neurosci (2006) 0.86
[18F]MPPF as a tool for the in vivo imaging of 5-HT1A receptors in animal and human brain. Neuropharmacology (2006) 0.86
Aggression and the three opioid families (endorphins, enkephalins, and dynorphins) in mice. Behav Genet (2003) 0.86
Test-retest reproducibility of 18F-MPPF PET in healthy humans: a reliability study. J Nucl Med (2007) 0.85
Functional correlates for 5-HT(1A) receptors in maternally deprived rats displaying anxiety and depression-like behaviors. Prog Neuropsychopharmacol Biol Psychiatry (2008) 0.85
Genetic inactivation of prokineticin receptor-1 leads to heart and kidney disorders. Arterioscler Thromb Vasc Biol (2011) 0.85
Biological rhythms and melatonin in mood disorders and their treatments. Pharmacol Ther (2013) 0.85
Differential long-term effects of MDMA on the serotoninergic system and hippocampal cell proliferation in 5-HTT knock-out vs. wild-type mice. Int J Neuropsychopharmacol (2008) 0.85
[18F]F15599, a novel 5-HT1A receptor agonist, as a radioligand for PET neuroimaging. Eur J Nucl Med Mol Imaging (2009) 0.85
Comparative analysis of cholinergic innervation in the dorsal hippocampus of adult mouse and rat: a quantitative immunocytochemical study. Hippocampus (2002) 0.85
Inhibition of gut- and lung-derived serotonin attenuates pulmonary hypertension in mice. Am J Physiol Lung Cell Mol Physiol (2012) 0.85
A postmortem study to compare agonist and antagonist 5-HT1A receptor-binding sites in Alzheimer's disease. CNS Neurosci Ther (2014) 0.84
Differential effects of the novel antidepressant agomelatine (S 20098) versus fluoxetine on 5-HT1A receptors in the rat brain. Neuropharmacology (2004) 0.84
Myotonic dystrophy CTG expansion affects synaptic vesicle proteins, neurotransmission and mouse behaviour. Brain (2013) 0.84
Sleep-stabilizing effects of E-6199, compared to zopiclone, zolpidem and THIP in mice. Sleep (2008) 0.84
N-methyl-D-aspartate receptor-mediated modulations of the anti-allodynic effects of 5-HT1B/1D receptor stimulation in a rat model of trigeminal neuropathic pain. Eur J Pain (2010) 0.84
Beyond the monoaminergic hypothesis: agomelatine, a new antidepressant with an innovative mechanism of action. World J Biol Psychiatry (2009) 0.84