PubRank

Thomas E Edwards

Author PubWeight™ 31.64‹?›

Top papers

Rank Title Journal Year PubWeight™‹?›
1 Cocrystal structure of a class I preQ1 riboswitch reveals a pseudoknot recognizing an essential hypermodified nucleobase. Nat Struct Mol Biol 2009 1.88
2 Thermodynamic analysis of ligand binding and ligand binding-induced tertiary structure formation by the thiamine pyrophosphate riboswitch. RNA 2009 1.48
3 Structure of hepatitis C virus polymerase in complex with primer-template RNA. J Virol 2012 1.39
4 High-throughput protein production and purification at the Seattle Structural Genomics Center for Infectious Disease. Acta Crystallogr Sect F Struct Biol Cryst Commun 2011 1.37
5 Structural basis for specific, high-affinity tetracycline binding by an in vitro evolved aptamer and artificial riboswitch. Chem Biol 2008 1.35
6 Unique motifs and hydrophobic interactions shape the binding of modified DNA ligands to protein targets. Proc Natl Acad Sci U S A 2012 1.28
7 SAD phasing using iodide ions in a high-throughput structural genomics environment. J Struct Funct Genomics 2011 1.23
8 Combining functional and structural genomics to sample the essential Burkholderia structome. PLoS One 2013 1.21
9 Nanometer distance measurements on RNA using PELDOR. J Am Chem Soc 2003 1.21
10 A new alpha-helical extension promotes RNA binding by the dsRBD of Rnt1p RNAse III. EMBO J 2004 1.12
11 The Protein Maker: an automated system for high-throughput parallel purification. Acta Crystallogr Sect F Struct Biol Cryst Commun 2011 0.99
12 Crystal structure of interleukin-6 in complex with a modified nucleic acid ligand. J Biol Chem 2014 0.96
13 Monitoring tat peptide binding to TAR RNA by solid-state 31P-19F REDOR NMR. Nucleic Acids Res 2005 0.94
14 Leveraging structure determination with fragment screening for infectious disease drug targets: MECP synthase from Burkholderia pseudomallei. J Struct Funct Genomics 2011 0.92
15 Nanovolume optimization of protein crystal growth using the microcapillary protein crystallization system. J Appl Crystallogr 2010 0.88
16 A structural biology approach enables the development of antimicrobials targeting bacterial immunophilins. Antimicrob Agents Chemother 2013 0.86
17 X-ray structure determination of the glycine cleavage system protein H of Mycobacterium tuberculosis using an inverse Compton synchrotron X-ray source. J Struct Funct Genomics 2010 0.85
18 Structural basis of the substrate specificity of bifunctional isocitrate dehydrogenase kinase/phosphatase. Biochemistry 2011 0.83
19 Structure of the cystathionine γ-synthase MetB from Mycobacterium ulcerans. Acta Crystallogr Sect F Struct Biol Cryst Commun 2011 0.83
20 An ensemble of structures of Burkholderia pseudomallei 2,3-bisphosphoglycerate-dependent phosphoglycerate mutase. Acta Crystallogr Sect F Struct Biol Cryst Commun 2011 0.83
21 Fragment screening of infectious disease targets in a structural genomics environment. Methods Enzymol 2011 0.82
22 Inhibitor-bound complexes of dihydrofolate reductase-thymidylate synthase from Babesia bovis. Acta Crystallogr Sect F Struct Biol Cryst Commun 2011 0.81
23 The impact of nitric oxide toxicity on the evolution of the glutathione transferase superfamily: a proposal for an evolutionary driving force. J Biol Chem 2013 0.81
24 Crystal structure of a macrophage migration inhibitory factor from Giardia lamblia. J Struct Funct Genomics 2013 0.80
25 Structure of fumarate hydratase from Rickettsia prowazekii, the agent of typhus and suspected relative of the mitochondria. Acta Crystallogr Sect F Struct Biol Cryst Commun 2011 0.78
26 BrabA.11339.a: anomalous diffraction and ligand binding guide towards the elucidation of the function of a 'putative β-lactamase-like protein' from Brucella melitensis. Acta Crystallogr Sect F Struct Biol Cryst Commun 2011 0.78
27 Structure of a Nudix hydrolase (MutT) in the Mg(2+)-bound state from Bartonella henselae, the bacterium responsible for cat scratch fever. Acta Crystallogr Sect F Struct Biol Cryst Commun 2011 0.77
28 Multi-target parallel processing approach for gene-to-structure determination of the influenza polymerase PB2 subunit. J Vis Exp 2013 0.77
29 Structural insights into the functional role of the Hcn sub-domain of the receptor-binding domain of the botulinum neurotoxin mosaic serotype C/D. Biochimie 2013 0.77
30 Cytidine derivatives as IspF inhibitors of Burkolderia pseudomallei. Bioorg Med Chem Lett 2013 0.76
31 Mycobacterium tuberculosis Rv2179c protein establishes a new exoribonuclease family with broad phylogenetic distribution. J Biol Chem 2013 0.75
32 Correction: Brucella melitensis Methionyl-tRNA-Synthetase (MetRS), a Potential Drug Target for Brucellosis. PLoS One 2016 0.75