Published in J Cell Sci on June 15, 2004
Phosphoproteome analysis of the human mitotic spindle. Proc Natl Acad Sci U S A (2006) 3.56
Proteomic screen defines the Polo-box domain interactome and identifies Rock2 as a Plk1 substrate. EMBO J (2007) 2.48
Cep55, a microtubule-bundling protein, associates with centralspindlin to control the midbody integrity and cell abscission during cytokinesis. Mol Biol Cell (2006) 2.02
Polo-like kinase 1 directs assembly of the HsCyk-4 RhoGAP/Ect2 RhoGEF complex to initiate cleavage furrow formation. PLoS Biol (2009) 2.02
Polo-box domain: a versatile mediator of polo-like kinase function. Cell Mol Life Sci (2010) 1.85
Kinesins and cancer. Nat Rev Cancer (2012) 1.84
Genome-wide microarray evidence that 8-cell human blastomeres over-express cell cycle drivers and under-express checkpoints. J Assist Reprod Genet (2010) 1.69
Phosphorylation- and polo-box-dependent binding of Plk1 to Bub1 is required for the kinetochore localization of Plk1. Mol Biol Cell (2006) 1.68
Plk4 is required for cytokinesis and maintenance of chromosomal stability. Proc Natl Acad Sci U S A (2010) 1.40
Requirement of hCenexin for proper mitotic functions of polo-like kinase 1 at the centrosomes. Mol Cell Biol (2006) 1.36
Functional dynamics of Polo-like kinase 1 at the centrosome. Mol Cell Biol (2009) 1.21
Recruitment of Polo kinase to the spindle midzone during cytokinesis requires the Feo/Klp3A complex. PLoS One (2007) 1.12
A genomic toolkit to investigate kinesin and myosin motor function in cells. Nat Cell Biol (2013) 1.11
Understanding cytokinesis failure. Adv Exp Med Biol (2010) 1.06
The novel mouse Polo-like kinase 5 responds to DNA damage and localizes in the nucleolus. Nucleic Acids Res (2010) 1.02
Liaisons between survivin and Plk1 during cell division and cell death. J Biol Chem (2010) 0.91
Local RhoA activation induces cytokinetic furrows independent of spindle position and cell cycle stage. J Cell Biol (2016) 0.88
Identification of novel variants in colorectal cancer families by high-throughput exome sequencing. Cancer Epidemiol Biomarkers Prev (2013) 0.88
Polo-like kinase 1, on the rise from cell cycle regulation to prostate cancer development. Protein Cell (2012) 0.83
Identification of potential Plk1 targets in a cell-cycle specific proteome through structural dynamics of kinase and Polo box-mediated interactions. PLoS One (2013) 0.81
lin9 is required for mitosis and cell survival during early zebrafish development. J Biol Chem (2009) 0.78
PLK1, A Potential Target for Cancer Therapy. Transl Oncol (2016) 0.77
Evaluation of KIF23 variant 1 expression and relevance as a novel prognostic factor in patients with hepatocellular carcinoma. BMC Cancer (2015) 0.75
Transcriptome analysis reveals potential mechanisms underlying differential heart development in fast- and slow-growing broilers under heat stress. BMC Genomics (2017) 0.75
Polo-like kinase (Plk)1 depletion induces apoptosis in cancer cells. Proc Natl Acad Sci U S A (2003) 2.81
Normal cells, but not cancer cells, survive severe Plk1 depletion. Mol Cell Biol (2006) 2.63
A spindle checkpoint arrest and a cytokinesis failure by the dominant-negative polo-box domain of Plk1 in U-2 OS cells. J Biol Chem (2002) 2.40
Activation of Cdc2/cyclin B and inhibition of centrosome amplification in cells depleted of Plk1 by siRNA. Proc Natl Acad Sci U S A (2002) 2.23
Kinesin-like protein CHO1 is required for the formation of midbody matrix and the completion of cytokinesis in mammalian cells. Mol Biol Cell (2002) 2.15
Phosphorylation of threonine 210 and the role of serine 137 in the regulation of mammalian polo-like kinase. J Biol Chem (2002) 2.15
MiR-375 frequently downregulated in gastric cancer inhibits cell proliferation by targeting JAK2. Cell Res (2010) 2.04
Functional studies on the role of the C-terminal domain of mammalian polo-like kinase. Proc Natl Acad Sci U S A (2002) 2.03
Down-regulation of miR-141 in gastric cancer and its involvement in cell growth. J Gastroenterol (2009) 1.73
Interaction of Aurora-A and centrosomin at the microtubule-nucleating site in Drosophila and mammalian cells. J Cell Biol (2003) 1.58
Characterization of Cep135, a novel coiled-coil centrosomal protein involved in microtubule organization in mammalian cells. J Cell Biol (2002) 1.56
A role for Plk1 phosphorylation of NudC in cytokinesis. Dev Cell (2003) 1.55
The MAP kinase pathway is required for entry into mitosis and cell survival. Oncogene (2004) 1.51
Metabolic stress controls mTORC1 lysosomal localization and dimerization by regulating the TTT-RUVBL1/2 complex. Mol Cell (2012) 1.50
Checkpoint kinase 1 (Chk1) is required for mitotic progression through negative regulation of polo-like kinase 1 (Plk1). Proc Natl Acad Sci U S A (2006) 1.47
Polo-like kinase 3 is required for entry into S phase. Proc Natl Acad Sci U S A (2007) 1.37
Requirement of hCenexin for proper mitotic functions of polo-like kinase 1 at the centrosomes. Mol Cell Biol (2006) 1.36
Mechanisms of mammalian polo-like kinase 1 (Plk1) localization: self- versus non-self-priming. Cell Cycle (2007) 1.33
Role of Plk2 (Snk) in mouse development and cell proliferation. Mol Cell Biol (2003) 1.33
Role of the midbody matrix in cytokinesis: RNAi and genetic rescue analysis of the mammalian motor protein CHO1. Mol Biol Cell (2004) 1.29
Polo-like kinase 1 depletion induces DNA damage in early S prior to caspase activation. Mol Cell Biol (2009) 1.25
Short term cyclin D1 overexpression induces centrosome amplification, mitotic spindle abnormalities, and aneuploidy. J Biol Chem (2004) 1.23
Differential control of Eg5-dependent centrosome separation by Plk1 and Cdk1. EMBO J (2011) 1.22
Hierarchical recruitment of Plk4 and regulation of centriole biogenesis by two centrosomal scaffolds, Cep192 and Cep152. Proc Natl Acad Sci U S A (2013) 1.18
Regulation of microtubule-based microtubule nucleation by mammalian polo-like kinase 1. Proc Natl Acad Sci U S A (2011) 1.15
CCT chaperonin complex is required for the biogenesis of functional Plk1. Mol Cell Biol (2005) 1.14
A Wnt/beta-catenin pathway antagonist Chibby binds Cenexin at the distal end of mother centrioles and functions in primary cilia formation. PLoS One (2012) 1.11
The G-protein regulatory (GPR) motif-containing Leu-Gly-Asn-enriched protein (LGN) and Gialpha3 influence cortical positioning of the mitotic spindle poles at metaphase in symmetrically dividing mammalian cells. Eur J Cell Biol (2006) 1.10
The serum-inducible protein kinase Snk is a G1 phase polo-like kinase that is inhibited by the calcium- and integrin-binding protein CIB. Mol Cancer Res (2003) 1.10
A mammalian NudC-like protein essential for dynein stability and cell viability. Proc Natl Acad Sci U S A (2006) 1.09
Homeobox D10 gene, a candidate tumor suppressor, is downregulated through promoter hypermethylation and associated with gastric carcinogenesis. Mol Med (2012) 1.03
TBCK influences cell proliferation, cell size and mTOR signaling pathway. PLoS One (2013) 0.99
Essential role of Cenexin1, but not Odf2, in ciliogenesis. Cell Cycle (2013) 0.99
Cdk2 plays a critical role in hepatocyte cell cycle progression and survival in the setting of cyclin D1 expression in vivo. Cell Cycle (2009) 0.97
MiR-215 modulates gastric cancer cell proliferation by targeting RB1. Cancer Lett (2013) 0.97
Feed-forward mechanism of converting biochemical cooperativity to mitotic processes at the kinetochore plate. Proc Natl Acad Sci U S A (2011) 0.96
Role of WNT7B-induced noncanonical pathway in advanced prostate cancer. Mol Cancer Res (2013) 0.93
Interaction of Cep135 with a p50 dynactin subunit in mammalian centrosomes. Cell Motil Cytoskeleton (2004) 0.92
ZIC1 is downregulated through promoter hypermethylation, and functions as a tumor suppressor gene in colorectal cancer. PLoS One (2011) 0.91
Polo-like kinase 1 in the life and death of cancer cells. Cell Cycle (2003) 0.91
MicroRNAs as diagnostic biomarkers in gastric cancer. Int J Mol Sci (2012) 0.91
Current management of hemorrhage from severe pelvic fractures: Results of an American Association for the Surgery of Trauma multi-institutional trial. J Trauma Acute Care Surg (2016) 0.89
Monitoring the cell cycle by multi-kinase-dependent regulation of Swe1/Wee1 in budding yeast. Cell Cycle (2005) 0.89
Collagen type I regulates beta-catenin tyrosine phosphorylation and nuclear translocation to promote migration and proliferation of gastric carcinoma cells. Oncol Rep (2010) 0.89
A potential role of collagens expression in distinguishing between premalignant and malignant lesions in stomach. Anat Rec (Hoboken) (2009) 0.89
The nuclear localization signal of mitotic kinesin-like protein Mklp-1: effect on Mklp-1 function during cytokinesis. Biochem Biophys Res Commun (2006) 0.87
Cell division cycle 6, a mitotic substrate of polo-like kinase 1, regulates chromosomal segregation mediated by cyclin-dependent kinase 1 and separase. Proc Natl Acad Sci U S A (2010) 0.87
Finding Plk3. Cell Cycle (2007) 0.86
NudC-like protein 2 regulates the LIS1/dynein pathway by stabilizing LIS1 with Hsp90. Proc Natl Acad Sci U S A (2010) 0.86
Centrosomal protein FOR20 is essential for S-phase progression by recruiting Plk1 to centrosomes. Cell Res (2013) 0.86
Plk1-targeted therapies in TP53- or RAS-mutated cancer. Mutat Res Rev Mutat Res (2014) 0.85
The L279P mutation of nuclear distribution gene C (NudC) influences its chaperone activity and lissencephaly protein 1 (LIS1) stability. J Biol Chem (2010) 0.85
Regulation of the final stage of mitosis by components of the pre-replicative complex and a polo kinase. Cell Cycle (2011) 0.84
Centrosome amplification in CHO and DT40 cells by inactivation of cyclin-dependent kinases. Cytoskeleton (Hoboken) (2011) 0.84
Ectopic expression of Plk1 leads to activation of the spindle checkpoint. Cell Cycle (2006) 0.84
Abnormal centrosomal structure and duplication in Cep135-deficient vertebrate cells. Mol Biol Cell (2013) 0.83
Inhibition of cytokinesis by overexpression of NudCL that is localized to the centrosome and midbody. Cell Res (2009) 0.82
Structural basis for the dephosphorylating activity of PTPRQ towards phosphatidylinositide substrates. Acta Crystallogr D Biol Crystallogr (2013) 0.81
Single-stage internal fixation for thoracolumbar spinal tuberculosis using 4 different surgical approaches. J Spinal Disord Tech (2014) 0.80
Targeting miR-375 in gastric cancer. Expert Opin Ther Targets (2011) 0.80
Converting a microarray signature into a diagnostic test: a trial of custom 74 gene array for clarification and prediction the prognosis of gastric cancer. PLoS One (2013) 0.79
ERK1/2 inhibition enhances apoptosis induced by JAK2 silencing in human gastric cancer SGC7901 cells. Mol Cell Biochem (2013) 0.79
A derivative of chrysin suppresses two-stage skin carcinogenesis by inhibiting mitogen- and stress-activated kinase 1. Cancer Prev Res (Phila) (2013) 0.79
A self-propelled biological process: Plk1-dependent, product-activated feedforward mechanism. Cell Cycle (2011) 0.78
Identification of 3-acyl-2-phenylamino-1,4-dihydroquinolin-4-one derivatives as inhibitors of the phosphatase SerB653 in Porphyromonas gingivalis, implicated in periodontitis. Bioorg Med Chem Lett (2012) 0.78
A chrysin derivative suppresses skin cancer growth by inhibiting cyclin-dependent kinases. J Biol Chem (2013) 0.78
Computed tomography abbreviated assessment of sarcopenia following trauma: The CAAST measurement predicts 6-month mortality in older adult trauma patients. J Trauma Acute Care Surg (2016) 0.77
Aggregation morphologies of a series of heterogemini surfactants with a hydroxyl head group in aqueous solution. Soft Matter (2014) 0.77
Role of REG Iα in gastric carcinogenesis: Gastrin-associated proliferative and anti-apoptotic activities. Mol Med Rep (2010) 0.77
Crystal structure of xenotropic murine leukaemia virus-related virus (XMRV) ribonuclease H. Biosci Rep (2012) 0.77
Crystal structure of constitutively monomeric E. coli Hsp33 mutant with chaperone activity. FEBS Lett (2011) 0.76
Treatment of Aseptic Necrosis of the Lunate Bone (Kienböck Disease) Using a Nickel-Titanium Memory Alloy Arthrodesis Concentrator: A Series of 24 Cases. Medicine (Baltimore) (2015) 0.75
Effects of the phosphatase inhibitors, okadaic acid, ATPgammaS, and calyculin A on the dividing sand dollar egg. Cell Struct Funct (2002) 0.75
Synthesis and antitumor activity of natural compound aloe emodin derivatives. Chem Biol Drug Des (2014) 0.75
Water-soluble MoS3 nanoparticles for photocatalytic H2 evolution. ChemSusChem (2015) 0.75
[Cationic liposome ceftazidime combined with nano-hydroxyapatite/beta-tricalcium phosphate for treatment of chronic osteomyelitis of rabbits]. Zhongguo Xiu Fu Chong Jian Wai Ke Za Zhi (2013) 0.75
[Surgical treatment of degenerative lumbar scoliosis with multi-segment lumbar spinal stenosis]. Zhongguo Xiu Fu Chong Jian Wai Ke Za Zhi (2014) 0.75
Pelvic fracture pattern predicts the need for hemorrhage control intervention-Results of an AAST multi-institutional study. J Trauma Acute Care Surg (2017) 0.75
Surgical rescue: The next pillar of acute care surgery. J Trauma Acute Care Surg (2016) 0.75
Porous carbon nitride nanosheets for enhanced photocatalytic activities. Nanoscale (2014) 0.75
[CLINICAL APPLICATION OF THREE DIMENSIONAL PRINTED NAVIGATION TEMPLATES FOR TREATMENT OF OSTEONECROSIS OF FEMORAL HEAD WITH PEDICLED ILIAC BONE GRAFT]. Zhongguo Xiu Fu Chong Jian Wai Ke Za Zhi (2016) 0.75
A highly efficient noble metal free photocatalytic hydrogen evolution system containing MoP and CdS quantum dots. Nanoscale (2016) 0.75
Pelvic fracture pattern predicts the need for hemorrhage control intervention -- results of a AAST multi-institutional study. J Trauma Acute Care Surg (2017) 0.75