Published in Transplantation on June 15, 2004
Thrombotic microangiopathy associated with humoral rejection of cardiac xenografts from alpha1,3-galactosyltransferase gene-knockout pigs in baboons. Am J Pathol (2008) 1.36
Recipient tissue factor expression is associated with consumptive coagulopathy in pig-to-primate kidney xenotransplantation. Am J Transplant (2010) 1.21
Coagulation dysregulation as a barrier to xenotransplantation in the primate. Transpl Immunol (2008) 1.17
Current status of xenotransplantation and prospects for clinical application. Xenotransplantation (2009) 1.15
Expression of tissue factor and initiation of clotting by human platelets and monocytes after incubation with porcine endothelial cells. Transplantation (2008) 1.01
Overcoming the barriers to xenotransplantation: prospects for the future. Expert Rev Clin Immunol (2010) 0.99
Antibody-mediated xenograft injury: mechanisms and protective strategies. Transpl Immunol (2009) 0.89
Pathologic characteristics of transplanted kidney xenografts. J Am Soc Nephrol (2011) 0.89
Kidney xenotransplantation. Kidney Int (2013) 0.88
Early graft failure of GalTKO pig organs in baboons is reduced by expression of a human complement pathway-regulatory protein. Xenotransplantation (2015) 0.87
Atorvastatin or transgenic expression of TFPI inhibits coagulation initiated by anti-nonGal IgG binding to porcine aortic endothelial cells. J Thromb Haemost (2010) 0.86
Immunobiological barriers to xenotransplantation. Int J Surg (2015) 0.82
Regulation of human platelet aggregation by genetically modified pig endothelial cells and thrombin inhibition. Xenotransplantation (2013) 0.82
Application of cyclophosphamide-induced tolerance in alpha1,3-galactosyltransferase knockout mice presensitized with Gal alpha 1-3Gal beta-4-GlcNAc antigens. Surg Today (2008) 0.77
Current status of pig kidney xenotransplantation. Int J Surg (2015) 0.77
Potential factors influencing the development of thrombocytopenia and consumptive coagulopathy after genetically modified pig liver xenotransplantation. Transpl Int (2012) 0.77
Minimal effect of bortezomib in reducing anti-pig antibodies in human leukocyte antigen-sensitized patients: a pilot study. Xenotransplantation (2013) 0.75
Generation of CMAHKO/GTKO/shTNFRI-Fc/HO-1 quadruple gene modified pigs. Transgenic Res (2017) 0.75
Adenosine generation catalyzed by CD39 and CD73 expressed on regulatory T cells mediates immune suppression. J Exp Med (2007) 10.00
Purinergic signaling during inflammation. N Engl J Med (2012) 4.08
Uric acid and survival in chronic heart failure: validation and application in metabolic, functional, and hemodynamic staging. Circulation (2003) 3.89
Coordinated adenine nucleotide phosphohydrolysis and nucleoside signaling in posthypoxic endothelium: role of ectonucleotidases and adenosine A2B receptors. J Exp Med (2003) 3.71
Alpha1,3-galactosyltransferase gene-knockout pigs for xenotransplantation: where do we go from here? Transplantation (2007) 3.65
Heart transplantation in baboons using alpha1,3-galactosyltransferase gene-knockout pigs as donors: initial experience. Nat Med (2004) 3.58
An emerging pattern of subtrochanteric stress fractures: a long-term complication of alendronate therapy? Injury (2008) 3.50
CD39 is the dominant Langerhans cell-associated ecto-NTPDase: modulatory roles in inflammation and immune responsiveness. Nat Med (2002) 3.18
Endogenous adenosine produced during hypoxia attenuates neutrophil accumulation: coordination by extracellular nucleotide metabolism. Blood (2004) 2.80
Acute rejection is associated with antibodies to non-Gal antigens in baboons using Gal-knockout pig kidneys. Nat Med (2005) 2.67
Dysfunctional CD39(POS) regulatory T cells and aberrant control of T-helper type 17 cells in autoimmune hepatitis. Hepatology (2014) 2.29
ATP release from activated neutrophils occurs via connexin 43 and modulates adenosine-dependent endothelial cell function. Circ Res (2006) 2.23
CD39/ectonucleoside triphosphate diphosphohydrolase 1 provides myocardial protection during cardiac ischemia/reperfusion injury. Circulation (2007) 2.09
Heart failure reversal by ventricular unloading in patients with chronic cardiomyopathy: criteria for weaning from ventricular assist devices. Eur Heart J (2010) 2.06
Prolonged survival of porcine hepatocytes in cynomolgus monkeys. Gastroenterology (2006) 2.04
Coagulopathy in cirrhosis - the role of the platelet in hemostasis. J Hepatol (2013) 2.01
Ectonucleotidases of CD39 family modulate vascular inflammation and thrombosis in transplantation. Semin Thromb Hemost (2005) 1.86
Clinical xenotransplantation: the next medical revolution? Lancet (2011) 1.84
Contribution of E-NTPDase1 (CD39) to renal protection from ischemia-reperfusion injury. FASEB J (2007) 1.84
Stat3 and Gfi-1 transcription factors control Th17 cell immunosuppressive activity via the regulation of ectonucleotidase expression. Immunity (2012) 1.82
Selected physiologic compatibilities and incompatibilities between human and porcine organ systems. Xenotransplantation (2006) 1.81
Thrombotic microangiopathic glomerulopathy in human decay accelerating factor-transgenic swine-to-baboon kidney xenografts. J Am Soc Nephrol (2005) 1.79
Central role of Sp1-regulated CD39 in hypoxia/ischemia protection. Blood (2008) 1.79
From the Cover: CD39 deletion exacerbates experimental murine colitis and human polymorphisms increase susceptibility to inflammatory bowel disease. Proc Natl Acad Sci U S A (2009) 1.75
Prediction of cardiac stability after weaning from left ventricular assist devices in patients with idiopathic dilated cardiomyopathy. Circulation (2008) 1.73
The mitochondrial uncoupling protein-2 promotes chemoresistance in cancer cells. Cancer Res (2008) 1.71
The early and late results of combined off-pump coronary artery bypass grafting and pulmonary resection in patients with concomitant lung cancer and unstable coronary heart disease. Eur J Cardiothorac Surg (2008) 1.70
Prognostic impact of microvasculopathy on survival after heart transplantation: evidence from 9713 endomyocardial biopsies. Circulation (2007) 1.69
CD39/ENTPD1 expression by CD4+Foxp3+ regulatory T cells promotes hepatic metastatic tumor growth in mice. Gastroenterology (2010) 1.69
CD39 and control of cellular immune responses. Purinergic Signal (2007) 1.68
Promotion of liver regeneration by natural killer cells in a murine model is dependent on extracellular adenosine triphosphate phosphohydrolysis. Hepatology (2013) 1.66
Salutary effects of adiponectin on colon cancer: in vivo and in vitro studies in mice. Gut (2012) 1.65
Hepatic function after genetically engineered pig liver transplantation in baboons. Transplantation (2010) 1.64
Thromboregulatory manifestations in human CD39 transgenic mice and the implications for thrombotic disease and transplantation. J Clin Invest (2004) 1.61
Sublethal heat treatment promotes epithelial-mesenchymal transition and enhances the malignant potential of hepatocellular carcinoma. Hepatology (2013) 1.59
Transcriptome characterization of estrogen-treated human myocardium identifies myosin regulatory light chain interacting protein as a sex-specific element influencing contractile function. J Am Coll Cardiol (2012) 1.56
alpha1,3-Galactosyltransferase gene-knockout pig heart transplantation in baboons with survival approaching 6 months. Transplantation (2005) 1.56
Heme oxygenase-1 and its reaction product, carbon monoxide, prevent inflammation-related apoptotic liver damage in mice. Hepatology (2003) 1.52
Extracellular UDP enhances P2X-mediated bladder smooth muscle contractility via P2Y(6) activation of the phospholipase C/inositol trisphosphate pathway. FASEB J (2013) 1.51
IL-27 acts on DCs to suppress the T cell response and autoimmunity by inducing expression of the immunoregulatory molecule CD39. Nat Immunol (2013) 1.50
Femoral cortical stress lesions in long-term bisphosphonate therapy: a herald of impending fracture? J Orthop Trauma (2010) 1.50
Investigation of red blood cells from alpha1,3-galactosyltransferase-knockout pigs for human blood transfusion. Transfusion (2004) 1.48
Carbon monoxide orchestrates a protective response through PPARgamma. Immunity (2006) 1.47
The innate immune response and activation of coagulation in alpha1,3-galactosyltransferase gene-knockout xenograft recipients. Transplantation (2009) 1.47
Xenogeneic thymus transplantation in a pig-to-baboon model. Transplantation (2003) 1.47
Clinical, haemodynamic and echocardiographic features of early cardiac graft dysfunction. Kardiol Pol (2012) 1.46
An industry perspective on the monitoring of subvisible particles as a quality attribute for protein therapeutics. J Pharm Sci (2010) 1.45
Ectonucleotidases as regulators of purinergic signaling in thrombosis, inflammation, and immunity. Adv Pharmacol (2011) 1.45
In vitro investigation of pig cells for resistance to human antibody-mediated rejection. Transpl Int (2008) 1.44
HGF and SDF-1-mediated mobilization of CD133+ BMSC for hepatic regeneration following extensive liver resection. Liver Int (2013) 1.42
Strain and strain rate imaging by echocardiography - basic concepts and clinical applicability. Curr Cardiol Rev (2009) 1.41
Extracellular nucleotide signaling in adult neural stem cells: synergism with growth factor-mediated cellular proliferation. Development (2006) 1.41
Left ventricular wall motion abnormality and myocardial dysfunction in stress cardiomyopathy: new pathophysiological aspects suggested by echocardiography. Int J Cardiol (2008) 1.40
Modulation of endothelial cell migration by extracellular nucleotides: involvement of focal adhesion kinase and phosphatidylinositol 3-kinase-mediated pathways. Thromb Haemost (2005) 1.38
Cloning and characterization of mouse nucleoside triphosphate diphosphohydrolase-8. Biochemistry (2004) 1.36
Thrombotic microangiopathy associated with humoral rejection of cardiac xenografts from alpha1,3-galactosyltransferase gene-knockout pigs in baboons. Am J Pathol (2008) 1.36
The ecto-nucleoside triphosphate diphosphohydrolase NTPDase2/CD39L1 is expressed in a novel functional compartment within the liver. Hepatology (2002) 1.34
Vascular CD39/ENTPD1 directly promotes tumor cell growth by scavenging extracellular adenosine triphosphate. Neoplasia (2011) 1.34
Disordered purinergic signaling inhibits pathological angiogenesis in cd39/Entpd1-null mice. Am J Pathol (2007) 1.32
Expression of the ecto-ATPase NTPDase2 in the germinal zones of the developing and adult rat brain. Eur J Neurosci (2003) 1.31
SP1-dependent induction of CD39 facilitates hepatic ischemic preconditioning. J Immunol (2010) 1.31
Ecto-nucleoside triphosphate diphosphohydrolase 1 (E-NTPDase1/CD39) regulates neutrophil chemotaxis by hydrolyzing released ATP to adenosine. J Biol Chem (2008) 1.31
Beneficial effects of CD39/ecto-nucleoside triphosphate diphosphohydrolase-1 in murine intestinal ischemia-reperfusion injury. Thromb Haemost (2004) 1.31
Attenuated, flow-induced ATP release contributes to absence of flow-sensitive, purinergic Cai2+ signaling in human ADPKD cyst epithelial cells. Am J Physiol Renal Physiol (2009) 1.28
P2Y receptors play a critical role in epithelial cell communication and migration. J Cell Biochem (2004) 1.27
Natural killer T cell dysfunction in CD39-null mice protects against concanavalin A-induced hepatitis. Hepatology (2008) 1.27
Predictors of endoscopic inflammation in patients with ulcerative colitis in clinical remission. Inflamm Bowel Dis (2013) 1.27
Expression of P2Y nucleotide receptors and ectonucleotidases in quiescent and activated rat hepatic stellate cells. Am J Physiol Gastrointest Liver Physiol (2004) 1.27
Clinical islet xenotransplantation: how close are we? Diabetes (2012) 1.26
Thrombotic microangiopathy and graft arteriopathy in pig hearts following transplantation into baboons. Xenotransplantation (2004) 1.26
Ecto-nucleotidases of the CD39/NTPDase family modulate platelet activation and thrombus formation: Potential as therapeutic targets. Blood Cells Mol Dis (2006) 1.24
The role of purinergic signaling in the liver and in transplantation: effects of extracellular nucleotides on hepatic graft vascular injury, rejection and metabolism. Front Biosci (2008) 1.24
Cooperative effect of biliverdin and carbon monoxide on survival of mice in immune-mediated liver injury. Hepatology (2004) 1.24
Rapid loss of intraportally transplanted islets: an overview of pathophysiology and preventive strategies. Xenotransplantation (2007) 1.20
Cell surface biliverdin reductase mediates biliverdin-induced anti-inflammatory effects via phosphatidylinositol 3-kinase and Akt. J Biol Chem (2009) 1.20
Upregulation of CD39/NTPDases and P2 receptors in human pancreatic disease. Am J Physiol Gastrointest Liver Physiol (2006) 1.19
Deletion of cd39/entpd1 results in hepatic insulin resistance. Diabetes (2008) 1.18
Coagulation dysregulation as a barrier to xenotransplantation in the primate. Transpl Immunol (2008) 1.17
Suppression of natural and elicited antibodies in pig-to-baboon heart transplantation using a human anti-human CD154 mAb-based regimen. Am J Transplant (2004) 1.17
Hormonal therapy of the brain-dead organ donor: experimental and clinical studies. Transplantation (2006) 1.17
Purinergic signaling during inflammation. N Engl J Med (2013) 1.17
The choice of anatomical site for islet transplantation. Cell Transplant (2008) 1.17