Published in Arch Neurol on June 01, 2004
Coenzyme Q10 in Huntington's Disease (HD) (2CARE) | NCT00608881
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Should we lower cholesterol as much as possible? BMJ (2006) 1.43
Primary and secondary CoQ(10) deficiencies in humans. Biofactors (2011) 1.09
Naturopathic medicine and type 2 diabetes: a retrospective analysis from an academic clinic. Altern Med Rev (2006) 1.07
CoQ10 deficiency diseases in adults. Mitochondrion (2007) 0.93
Coenzyme q10 and statin-induced mitochondrial dysfunction. Ochsner J (2010) 0.93
Impact of adherence to statins on chronic heart failure in primary prevention. Br J Clin Pharmacol (2008) 0.91
Lipid-lowering medication use and aggression scores in women: a report from the NHLBI-sponsored WISE study. J Womens Health (Larchmt) (2008) 0.90
Coenzyme Q10 levels are low and may be associated with the inflammatory cascade in septic shock. Crit Care (2011) 0.89
The effects of statins on the mevalonic acid pathway in recombinant yeast strains expressing human HMG-CoA reductase. BMC Biotechnol (2013) 0.89
Statins in heart failure: do we need another trial? Vasc Health Risk Manag (2013) 0.88
Protection of rat skeletal muscle fibers by either L-carnitine or coenzyme Q10 against statins toxicity mediated by mitochondrial reactive oxygen generation. Front Physiol (2013) 0.83
Effect of Coenzyme Q10 Supplementation in Statin-Treated Obese Rats. Biomol Ther (Seoul) (2016) 0.82
Statins more than cholesterol lowering agents in Alzheimer disease: their pleiotropic functions as potential therapeutic targets. Biochem Pharmacol (2013) 0.80
Plasma Coenzyme Q10 Predicts Lipid-lowering Response to High-Dose Atorvastatin. J Clin Lipidol (2008) 0.79
Rosuvastatin and atorvastatin: comparative effects on glucose metabolism in non-diabetic patients with dyslipidaemia. Clin Med Insights Endocrinol Diabetes (2012) 0.79
Benefits & risks of statin therapy for primary prevention of cardiovascular disease in Asian Indians - a population with the highest risk of premature coronary artery disease & diabetes. Indian J Med Res (2013) 0.79
Statin-induced Myopathy. Glob Adv Health Med (2012) 0.79
Statin-associated polymyositis following omeprazole treatment. Clin Med Res (2013) 0.77
Ubisol-Q10 Prevents Glutamate-Induced Cell Death by Blocking Mitochondrial Fragmentation and Permeability Transition Pore Opening. Int J Biol Sci (2016) 0.77
Molecular mechanisms of statin intolerance. Arch Med Sci (2016) 0.77
Coenzyme Q10 and cognition in atorvastatin treated dogs. Neurosci Lett (2011) 0.76
The Interaction Between Statins and Exercise: Mechanisms and Strategies to Counter the Musculoskeletal Side Effects of This Combination Therapy. Ochsner J (2015) 0.75
Rhabdomyolysis in the setting of induced hypothyroidism and statin therapy: a case report. Eur Thyroid J (2015) 0.75
Should we lower cholesterol as much as possible? Cholesterol is good? BMJ (2006) 0.75
Effect of rosuvastatin on plasma coenzyme Q10 in HIV-infected individuals on antiretroviral therapy. HIV Clin Trials (2016) 0.75
Atorvastatin but Not Pravastatin Impairs Mitochondrial Function in Human Pancreatic Islets and Rat β-Cells. Direct Effect of Oxidative Stress. Sci Rep (2017) 0.75
Heart disease and stroke statistics--2010 update: a report from the American Heart Association. Circulation (2009) 27.89
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Executive summary: heart disease and stroke statistics--2010 update: a report from the American Heart Association. Circulation (2010) 9.18
MPV17 encodes an inner mitochondrial membrane protein and is mutated in infantile hepatic mitochondrial DNA depletion. Nat Genet (2006) 3.17
Cyclooxygenase-2 is instrumental in Parkinson's disease neurodegeneration. Proc Natl Acad Sci U S A (2003) 2.74
A mutation in para-hydroxybenzoate-polyprenyl transferase (COQ2) causes primary coenzyme Q10 deficiency. Am J Hum Genet (2005) 2.73
Leigh syndrome with nephropathy and CoQ10 deficiency due to decaprenyl diphosphate synthase subunit 2 (PDSS2) mutations. Am J Hum Genet (2006) 2.66
Human mitochondrial DNA: roles of inherited and somatic mutations. Nat Rev Genet (2012) 2.59
D-beta-hydroxybutyrate rescues mitochondrial respiration and mitigates features of Parkinson disease. J Clin Invest (2003) 2.25
Deficiency of tetralinoleoyl-cardiolipin in Barth syndrome. Ann Neurol (2002) 2.14
ADCK3, an ancestral kinase, is mutated in a form of recessive ataxia associated with coenzyme Q10 deficiency. Am J Hum Genet (2008) 2.04
White matter hyperintensities and subclinical infarction: associations with psychomotor speed and cognitive flexibility. Stroke (2008) 1.84
The association between endothelial dysfunction and cardiovascular outcomes in a population-based multi-ethnic cohort. Atherosclerosis (2006) 1.83
Heterogeneity of coenzyme Q10 deficiency: patient study and literature review. Arch Neurol (2012) 1.77
High-sensitivity C-reactive protein, lipoprotein-associated phospholipase A2, and outcome after ischemic stroke. Arch Intern Med (2006) 1.73
The myopathic form of coenzyme Q10 deficiency is caused by mutations in the electron-transferring-flavoprotein dehydrogenase (ETFDH) gene. Brain (2007) 1.73
Mitochondrial DNA deletions inhibit proteasomal activity and stimulate an autophagic transcript. Free Radic Biol Med (2006) 1.73
Missense mutation of the COQ2 gene causes defects of bioenergetics and de novo pyrimidine synthesis. Hum Mol Genet (2007) 1.67
Varying loads of the mitochondrial DNA A3243G mutation in different tissues: implications for diagnosis. Am J Med Genet A (2004) 1.64
Impact of resting heart rate on mortality, disability and cognitive decline in patients after ischaemic stroke. Eur Heart J (2012) 1.62
Phospholipid abnormalities in children with Barth syndrome. J Am Coll Cardiol (2003) 1.59
Human NARP mitochondrial mutation metabolism corrected with alpha-ketoglutarate/aspartate: a potential new therapy. Arch Neurol (2009) 1.58
A homoplasmic mitochondrial transfer ribonucleic acid mutation as a cause of maternally inherited hypertrophic cardiomyopathy. J Am Coll Cardiol (2003) 1.57
Navajo neurohepatopathy is caused by a mutation in the MPV17 gene. Am J Hum Genet (2006) 1.53
Altered thymidine metabolism due to defects of thymidine phosphorylase. J Biol Chem (2001) 1.52
Mitochondrial DNA abnormalities and autistic spectrum disorders. J Pediatr (2004) 1.49
Coenzyme Q10 levels are low and associated with increased mortality in post-cardiac arrest patients. Resuscitation (2012) 1.47
Coenzyme Q-responsive Leigh's encephalopathy in two sisters. Ann Neurol (2002) 1.45
Respiratory chain dysfunction and oxidative stress correlate with severity of primary CoQ10 deficiency. FASEB J (2008) 1.41
Pathogenic exon-trapping by SVA retrotransposon and rescue in Fukuyama muscular dystrophy. Nature (2011) 1.41
Mitochondrial DNA depletion syndrome due to mutations in the RRM2B gene. Neuromuscul Disord (2008) 1.39
Reactive oxygen species, oxidative stress, and cell death correlate with level of CoQ10 deficiency. FASEB J (2010) 1.36
The spectrum of exercise tolerance in mitochondrial myopathies: a study of 40 patients. Brain (2003) 1.35
Risk of developing a mitochondrial DNA deletion disorder. Lancet (2004) 1.34
Human coenzyme Q10 deficiency. Neurochem Res (2006) 1.34
Inflammatory biomarkers of vascular risk as correlates of leukoariosis. Stroke (2009) 1.32
Early-onset familial parkinsonism due to POLG mutations. Ann Neurol (2006) 1.31
Mitochondrial dysfunction in mut methylmalonic acidemia. FASEB J (2008) 1.31
Loss-of-function mutations in MGME1 impair mtDNA replication and cause multisystemic mitochondrial disease. Nat Genet (2013) 1.30
Clinical and genetic heterogeneity in progressive external ophthalmoplegia due to mutations in polymerase gamma. Arch Neurol (2003) 1.29
Lack of paternal inheritance of muscle mitochondrial DNA in sporadic mitochondrial myopathies. Ann Neurol (2003) 1.28
Treatment of CoQ(10) deficient fibroblasts with ubiquinone, CoQ analogs, and vitamin C: time- and compound-dependent effects. PLoS One (2010) 1.26
Metabolic syndrome, endothelial dysfunction, and risk of cardiovascular events: the Northern Manhattan Study (NOMAS). Am Heart J (2008) 1.22
POLG mutations and Alpers syndrome. Ann Neurol (2005) 1.19
Therapeutic prospects for mitochondrial disease. Trends Mol Med (2010) 1.17
Copper supplementation restores cytochrome c oxidase activity in cultured cells from patients with SCO2 mutations. Biochem J (2002) 1.17
A functionally dominant mitochondrial DNA mutation. Hum Mol Genet (2008) 1.17
Mitochondrial DNA depletion and dGK gene mutations. Ann Neurol (2002) 1.17
Next-generation sequencing reveals DGUOK mutations in adult patients with mitochondrial DNA multiple deletions. Brain (2012) 1.16
Effect of the Glycine Antagonist Gavestinel on cerebral infarcts in acute stroke patients, a randomized placebo-controlled trial: The GAIN MRI Substudy. Cerebrovasc Dis (2005) 1.16
Nerve conduction abnormalities in patients with MELAS and the A3243G mutation. Arch Neurol (2006) 1.15
Protean phenotypic features of the A3243G mitochondrial DNA mutation. Arch Neurol (2009) 1.15
Social determinants of physical inactivity in the Northern Manhattan Study (NOMAS). J Community Health (2010) 1.14
Effect of ezetimibe and/or simvastatin on coenzyme Q10 levels in plasma: a randomised trial. Drug Saf (2006) 1.12
Primary coenzyme Q10 deficiency and the brain. Biofactors (2003) 1.11
Molecular basis of infantile reversible cytochrome c oxidase deficiency myopathy. Brain (2009) 1.10
Short communication: transplacental nucleoside analogue exposure and mitochondrial parameters in HIV-uninfected children. AIDS Res Hum Retroviruses (2011) 1.09
Neutral lipid storage disease with subclinical myopathy due to a retrotransposal insertion in the PNPLA2 gene. Neuromuscul Disord (2010) 1.09
Novel mutations in the adipose triglyceride lipase gene causing neutral lipid storage disease with myopathy. Biochem Biophys Res Commun (2008) 1.07
Mitochondrial fusion and function in Charcot-Marie-Tooth type 2A patient fibroblasts with mitofusin 2 mutations. Exp Neurol (2008) 1.07
MERRF and Kearns-Sayre overlap syndrome due to the mitochondrial DNA m.3291T>C mutation. Muscle Nerve (2011) 1.07
ANO10 mutations cause ataxia and coenzyme Q₁₀ deficiency. J Neurol (2014) 1.07
Glycogen synthase (GYS1) mutation causes a novel skeletal muscle glycogenosis. Genomics (2008) 1.06
Coenzyme Q deficiency in muscle. Curr Opin Neurol (2011) 1.05
Clinical spectrum of mitochondrial DNA depletion due to mutations in the thymidine kinase 2 gene. Arch Neurol (2006) 1.05
New insights in the field of muscle glycogenoses. Curr Opin Neurol (2013) 1.05
Progressive external ophthalmoplegia and vision and hearing loss in a patient with mutations in POLG2 and OPA1. Arch Neurol (2008) 1.04
Novel mitochondrial DNA ND5 mutation in a patient with clinical features of MELAS and MERRF. Arch Neurol (2005) 1.03
A new muscle glycogen storage disease associated with glycogenin-1 deficiency. Ann Neurol (2014) 1.03
Mutation screening in patients with isolated cytochrome c oxidase deficiency. Pediatr Res (2003) 1.02
Mitochondrial myopathy of childhood associated with mitochondrial DNA depletion and a homozygous mutation (T77M) in the TK2 gene. Arch Neurol (2003) 1.02
Muscle coenzyme Q10 level in statin-related myopathy. Arch Neurol (2005) 1.01
Alterations in plasma complement levels after human ischemic stroke. Neurosurgery (2006) 1.00
A novel polymerase gamma mutation in a family with ophthalmoplegia, neuropathy, and Parkinsonism. Arch Neurol (2004) 0.99
Fatal infantile neuromuscular presentation of glycogen storage disease type IV. Neuromuscul Disord (2004) 0.97
An investigation of statistical power for continuous arterial spin labeling imaging at 1.5 T. Neuroimage (2007) 0.97
Effect of telmisartan on functional outcome, recurrence, and blood pressure in patients with acute mild ischemic stroke: a PRoFESS subgroup analysis. Stroke (2009) 0.96
MPV17 Mutations Causing Adult-Onset Multisystemic Disorder With Multiple Mitochondrial DNA Deletions. Arch Neurol (2012) 0.96
TMEM14C is required for erythroid mitochondrial heme metabolism. J Clin Invest (2014) 0.96
A diagnostic algorithm for metabolic myopathies. Curr Neurol Neurosci Rep (2010) 0.96
Levels of acute phase proteins remain stable after ischemic stroke. BMC Neurol (2006) 0.95
Mutant COQ2 in multiple-system atrophy. N Engl J Med (2014) 0.95
Effects of inhibiting CoQ10 biosynthesis with 4-nitrobenzoate in human fibroblasts. PLoS One (2012) 0.94
Cerebral metabolic abnormalities in A3243G mitochondrial DNA mutation carriers. Neurology (2014) 0.94
Aortic rupture in mitochondrial encephalopathy, lactic acidosis, and stroke-like episodes. Arch Neurol (2006) 0.93
Genome-wide association analysis identifies a mutation in the thiamine transporter 2 (SLC19A3) gene associated with Alaskan Husky encephalopathy. PLoS One (2013) 0.93
CoQ10 deficiency diseases in adults. Mitochondrion (2007) 0.93
Oxidative stress biomarkers in sporadic ALS. Amyotroph Lateral Scler (2008) 0.93
Exercise-induced cramp, myoglobinuria, and tubular aggregates in phosphoglycerate mutase deficiency. Muscle Nerve (2006) 0.93
A novel mitochondrial tRNA(Leu(UUR)) mutation in a patient with features of MERRF and Kearns-Sayre syndrome. Neuromuscul Disord (2003) 0.91
Infantile encephaloneuromyopathy and defective mitochondrial translation are due to a homozygous RMND1 mutation. Am J Hum Genet (2012) 0.91
Cytochrome c oxidase deficiency due to a novel SCO2 mutation mimics Werdnig-Hoffmann disease. Arch Neurol (2002) 0.91