Published in Amyotroph Lateral Scler on June 01, 2008
Molecular pathways of motor neuron injury in amyotrophic lateral sclerosis. Nat Rev Neurol (2011) 2.73
Phase II trial of CoQ10 for ALS finds insufficient evidence to justify phase III. Ann Neurol (2009) 1.31
Nutraceutical antioxidants as novel neuroprotective agents. Molecules (2010) 1.29
Mechanisms, models and biomarkers in amyotrophic lateral sclerosis. Amyotroph Lateral Scler Frontotemporal Degener (2013) 1.16
Is SOD1 loss of function involved in amyotrophic lateral sclerosis? Brain (2013) 1.05
Clinical perspective on oxidative stress in sporadic amyotrophic lateral sclerosis. Free Radic Biol Med (2013) 1.03
Candidate proteins, metabolites and transcripts in the Biomarkers for Spinal Muscular Atrophy (BforSMA) clinical study. PLoS One (2012) 0.95
ALS Multicenter Cohort Study of Oxidative Stress (ALS COSMOS): study methodology, recruitment, and baseline demographic and disease characteristics. Amyotroph Lateral Scler Frontotemporal Degener (2014) 0.94
Protein oxidative modifications in the ageing brain: consequence for the onset of neurodegenerative disease. Free Radic Res (2010) 0.93
The application of biomarkers in clinical trials for motor neuron disease. Biomark Med (2010) 0.92
The wobbler mouse, an ALS animal model. Mol Genet Genomics (2013) 0.92
Genetic biomarkers for ALS disease in transgenic SOD1(G93A) mice. PLoS One (2012) 0.91
Applying proteomics to the diagnosis and treatment of ALS and related diseases. Muscle Nerve (2009) 0.89
Oxidative Stress in Neurodegenerative Diseases. Mol Neurobiol (2015) 0.89
Isoprostanes and neuroprostanes as biomarkers of oxidative stress in neurodegenerative diseases. Oxid Med Cell Longev (2014) 0.88
Role of ROS and RNS Sources in Physiological and Pathological Conditions. Oxid Med Cell Longev (2016) 0.84
Humoral factors in ALS patients during disease progression. J Neuroinflammation (2015) 0.81
Roles of vitamin D in amyotrophic lateral sclerosis: possible genetic and cellular signaling mechanisms. Mol Brain (2013) 0.79
Voltammetric microwell array for oxidized guanosine in intact ds-DNA. Anal Chem (2013) 0.79
Classifying oxidative stress by F2-isoprostane levels across human diseases: A meta-analysis. Redox Biol (2017) 0.79
A Temporal Association between Accumulated Petrol (Gasoline) Lead Emissions and Motor Neuron Disease in Australia. Int J Environ Res Public Health (2015) 0.78
Fluid-Based Biomarkers for Amyotrophic Lateral Sclerosis. Neurotherapeutics (2016) 0.78
Glutathione peroxidase 4: a new player in neurodegeneration? Mol Psychiatry (2016) 0.75
Positron emission tomography in amyotrophic lateral sclerosis: Towards targeting of molecular pathological hallmarks. Eur J Nucl Med Mol Imaging (2016) 0.75
The ALSFRS-R: a revised ALS functional rating scale that incorporates assessments of respiratory function. BDNF ALS Study Group (Phase III). J Neurol Sci (1999) 9.95
Unraveling the mechanisms involved in motor neuron degeneration in ALS. Annu Rev Neurosci (2004) 6.99
Oxidative stress in neurodegeneration: cause or consequence? Nat Med (2004) 4.72
Decline in skeletal muscle mitochondrial function with aging in humans. Proc Natl Acad Sci U S A (2005) 4.03
Occurrence of amyotrophic lateral sclerosis among Gulf War veterans. Neurology (2003) 3.82
Prospective study of military service and mortality from ALS. Neurology (2005) 3.59
Isoprostanes: markers and mediators of oxidative stress. FASEB J (2004) 2.83
Protein carbonylation, cellular dysfunction, and disease progression. J Cell Mol Med (2006) 2.59
Protein carbonyl measurement by a sensitive ELISA method. Free Radic Biol Med (1997) 2.14
Repair of 8-oxodeoxyguanosine lesions in mitochondrial dna depends on the oxoguanine dna glycosylase (OGG1) gene and 8-oxoguanine accumulates in the mitochondrial dna of OGG1-defective mice. Cancer Res (2001) 2.04
Oxidative stress, chronic disease, and muscle wasting. Muscle Nerve (2007) 1.97
Oxidative stress in brain aging, neurodegenerative and vascular diseases: an overview. J Chromatogr B Analyt Technol Biomed Life Sci (2005) 1.86
Creatine in Huntington disease is safe, tolerable, bioavailable in brain and reduces serum 8OH2'dG. Neurology (2006) 1.73
Molecular and cellular pathways of neurodegeneration in motor neurone disease. J Neurol Neurosurg Psychiatry (2005) 1.55
The pathogenesis of clinical depression: stressor- and cytokine-induced alterations of neuroplasticity. Neuroscience (2005) 1.55
Relationship between urinary 15-F2t-isoprostane and 8-oxodeoxyguanosine levels and breast cancer risk. Cancer Epidemiol Biomarkers Prev (2006) 1.48
Serum myeloperoxidase and mortality in maintenance hemodialysis patients. Am J Kidney Dis (2006) 1.44
Effects of age and caloric restriction on lipid peroxidation: measurement of oxidative stress by F2-isoprostane levels. J Gerontol A Biol Sci Med Sci (2005) 1.41
Nutritional status is a prognostic factor for survival in ALS patients. Neurology (1999) 1.40
Organophosphorus ester-induced chronic neurotoxicity. Arch Environ Health (2003) 1.37
Population-based case-control study of amyotrophic lateral sclerosis in western Washington State. I. Cigarette smoking and alcohol consumption. Am J Epidemiol (2000) 1.36
Determination of 8-hydroxydeoxyguanosine by an immunoaffinity chromatography-monoclonal antibody-based ELISA. Free Radic Biol Med (1995) 1.35
Systemic increase of oxidative nucleic acid damage in Parkinson's disease and multiple system atrophy. Neurobiol Dis (2002) 1.34
Magnetic-field-induced DNA strand breaks in brain cells of the rat. Environ Health Perspect (2004) 1.33
The isoprostanes: their quantification as an index of oxidant stress status in vivo. Drug Metab Rev (2001) 1.31
Increased oxidative damage to DNA in ALS patients. Free Radic Biol Med (2000) 1.29
Abnormal glutamate metabolism in amyotrophic lateral sclerosis. Ann Neurol (1987) 1.29
Hypermetabolism in ALS: correlations with clinical and paraclinical parameters. Neurodegener Dis (2005) 1.26
A carbon column-based liquid chromatography electrochemical approach to routine 8-hydroxy-2'-deoxyguanosine measurements in urine and other biologic matrices: a one-year evaluation of methods. Free Radic Biol Med (1999) 1.23
Exercise-induced oxidative stress:myths, realities and physiological relevance. Sports Med (2005) 1.22
Mitochondrial alterations in the spinal cord of patients with sporadic amyotrophic lateral sclerosis. J Neuropathol Exp Neurol (2007) 1.20
Increased CSF F2-isoprostane concentration in probable AD. Neurology (1999) 1.19
The skin in amyotrophic lateral sclerosis. Amyotroph Lateral Scler Other Motor Neuron Disord (2000) 1.18
Increased lipid peroxidation in sera of ALS patients: a potential biomarker of disease burden. Neurology (2004) 1.15
Tobacco smoke induces both apoptosis and necrosis in mammalian cells: differential effects of HSP70. Am J Physiol (1998) 1.13
Acrolein induces axolemmal disruption, oxidative stress, and mitochondrial impairment in spinal cord tissue. Neurochem Int (2004) 1.11
Mitochondria in amyotrophic lateral sclerosis: a trigger and a target. Neurodegener Dis (2004) 1.07
Endogenous oxidative damage of mtDNA. Mutat Res (1999) 1.07
Comparison between high-performance liquid chromatography and enzyme-linked immunosorbent assay for the determination of 8-hydroxy-2'-deoxyguanosine in human urine. Cancer Epidemiol Biomarkers Prev (2002) 1.05
Investigation of the therapeutic effects of edaravone, a free radical scavenger, on amyotrophic lateral sclerosis (Phase II study). Amyotroph Lateral Scler (2006) 1.05
Oxidative stress induced by lead, cadmium and arsenic mixtures: 30-day, 90-day, and 180-day drinking water studies in rats: an overview. Biometals (2004) 1.03
Chronic obstructive pulmonary disease: effects beyond the lungs. Curr Opin Pulm Med (2006) 1.00
Urinary 8-hydroxydeoxyguanosine levels as a biomarker for progression of Parkinson disease. Neurology (2005) 0.93
Nitration of manganese superoxide dismutase in cerebrospinal fluids is a marker for peroxynitrite-mediated oxidative stress in neurodegenerative diseases. Ann Neurol (2000) 0.88
Increased isoprostane and prostaglandin are prominent in neurons in Alzheimer disease. Mol Neurodegener (2007) 0.88
The involvement of copper transporter in lead-induced oxidative stress in astroglia. Neurochem Res (2005) 0.87
Blood oxidative stress in amyotrophic lateral sclerosis. J Neurol Sci (2000) 0.87
Oxidative stress in rat cortical neurons and astrocytes induced by paraquat in vitro. Neurotox Res (2002) 0.86
Mitochondriopathy mimicking amyotrophic lateral sclerosis. Neurologist (2003) 0.85
Alterations in anti-oxidative defence enzymes in erythrocytes from sporadic amyotrophic lateral sclerosis (SALS) and familial ALS patients. Clin Chem Lab Med (2006) 0.84
Is ALS a systemic disorder? Evidence from muscle mitochondria. Exp Neurol (2006) 0.81
Lead-induced cell death of human neuroblastoma cells involves GSH deprivation. Cell Mol Biol Lett (2005) 0.81
Mechanism of organophosphates (nerve gases and pesticides) and antidotes: electron transfer and oxidative stress. Curr Med Chem (2003) 0.80
The advanced glycation end-product N epsilon-(carboxymethyl)lysine level is elevated in cerebrospinal fluid of patients with amyotrophic lateral sclerosis. Neurosci Lett (2004) 0.78
Cancer-related cachexia and oxidative stress: beyond current therapeutic options. Expert Rev Anticancer Ther (2003) 0.77
Effect of selenium and vitamin E on risk of prostate cancer and other cancers: the Selenium and Vitamin E Cancer Prevention Trial (SELECT). JAMA (2008) 13.35
A metagenomic survey of microbes in honey bee colony collapse disorder. Science (2007) 11.72
Broadly cross-reactive antibodies dominate the human B cell response against 2009 pandemic H1N1 influenza virus infection. J Exp Med (2011) 7.29
Water arsenic exposure and children's intellectual function in Araihazar, Bangladesh. Environ Health Perspect (2004) 5.19
The Breast Cancer Family Registry: an infrastructure for cooperative multinational, interdisciplinary and translational studies of the genetic epidemiology of breast cancer. Breast Cancer Res (2004) 4.54
Association between maternal use of folic acid supplements and risk of autism spectrum disorders in children. JAMA (2013) 4.08
Neuropsychological prediction of conversion to Alzheimer disease in patients with mild cognitive impairment. Arch Gen Psychiatry (2006) 3.44
Water manganese exposure and children's intellectual function in Araihazar, Bangladesh. Environ Health Perspect (2006) 3.42
Mutant LRRK2(R1441G) BAC transgenic mice recapitulate cardinal features of Parkinson's disease. Nat Neurosci (2009) 3.24
Measles outbreak--California, December 2014-February 2015. MMWR Morb Mortal Wkly Rep (2015) 3.20
Designing the Selenium and Vitamin E Cancer Prevention Trial (SELECT). J Natl Cancer Inst (2005) 2.99
California pertussis epidemic, 2010. J Pediatr (2012) 2.91
Environmental toxins and breast cancer on Long Island. I. Polycyclic aromatic hydrocarbon DNA adducts. Cancer Epidemiol Biomarkers Prev (2002) 2.83
Cyclooxygenase-2 is instrumental in Parkinson's disease neurodegeneration. Proc Natl Acad Sci U S A (2003) 2.74
A mutation in para-hydroxybenzoate-polyprenyl transferase (COQ2) causes primary coenzyme Q10 deficiency. Am J Hum Genet (2005) 2.73
The Long Island Breast Cancer Study Project: description of a multi-institutional collaboration to identify environmental risk factors for breast cancer. Breast Cancer Res Treat (2002) 2.71
Short telomere length and breast cancer risk: a study in sister sets. Cancer Res (2007) 2.70
Astrovirus encephalitis in boy with X-linked agammaglobulinemia. Emerg Infect Dis (2010) 2.69
Leigh syndrome with nephropathy and CoQ10 deficiency due to decaprenyl diphosphate synthase subunit 2 (PDSS2) mutations. Am J Hum Genet (2006) 2.66
Cognitive deficits predict low treatment retention in cocaine dependent patients. Drug Alcohol Depend (2005) 2.66
Streptococcus pneumoniae coinfection is correlated with the severity of H1N1 pandemic influenza. PLoS One (2009) 2.65
Effects of major depression on remission and relapse of substance dependence. Arch Gen Psychiatry (2002) 2.56
Genomic DNA methylation among women in a multiethnic New York City birth cohort. Cancer Epidemiol Biomarkers Prev (2008) 2.52
DNA methylation in white blood cells: association with risk factors in epidemiologic studies. Epigenetics (2011) 2.51
Water arsenic exposure and intellectual function in 6-year-old children in Araihazar, Bangladesh. Environ Health Perspect (2006) 2.50
Analysis of self-selection bias in a population-based cohort study of autism spectrum disorders. Paediatr Perinat Epidemiol (2013) 2.42
Folate and arsenic metabolism: a double-blind, placebo-controlled folic acid-supplementation trial in Bangladesh. Am J Clin Nutr (2006) 2.41
A novel, efficient, randomized selection trial comparing combinations of drug therapy for ALS. Amyotroph Lateral Scler (2008) 2.28
D-beta-hydroxybutyrate rescues mitochondrial respiration and mitigates features of Parkinson disease. J Clin Invest (2003) 2.25
DNA repair capacity of lymphoblastoid cell lines from sisters discordant for breast cancer. J Natl Cancer Inst (2005) 2.20
Significant differences in global genomic DNA methylation by gender and race/ethnicity in peripheral blood. Epigenetics (2011) 2.12
Novel borna virus in psittacine birds with proventricular dilatation disease. Emerg Infect Dis (2008) 2.10
Metabolomic profiling to develop blood biomarkers for Parkinson's disease. Brain (2008) 2.10
Associations between breast cancer risk and the catalase genotype, fruit and vegetable consumption, and supplement use. Am J Epidemiol (2005) 2.03
Predicting hepatocellular carcinoma by detection of aberrant promoter methylation in serum DNA. Clin Cancer Res (2007) 2.02
Elevated blood harmane (1-methyl-9H-pyrido[3,4-b]indole) concentrations in essential tremor. Neurotoxicology (2007) 1.98
Folate, homocysteine, and arsenic metabolism in arsenic-exposed individuals in Bangladesh. Environ Health Perspect (2005) 1.97
Global methylation profiles in DNA from different blood cell types. Epigenetics (2011) 1.94
Combining early markers strongly predicts conversion from mild cognitive impairment to Alzheimer's disease. Biol Psychiatry (2008) 1.93
Increased plaque burden in brains of APP mutant MnSOD heterozygous knockout mice. J Neurochem (2004) 1.92
Genomic methylation of peripheral blood leukocyte DNA: influences of arsenic and folate in Bangladeshi adults. Am J Clin Nutr (2007) 1.91
Lipid-dependent membrane protein topogenesis. Annu Rev Biochem (2009) 1.91
Folate, Cobalamin, Cysteine, Homocysteine, and Arsenic Metabolism among Children in Bangladesh. Environ Health Perspect (2009) 1.83
Arsenic and manganese exposure and children's intellectual function. Neurotoxicology (2011) 1.82
Acid suppression therapy may not alter malignant progression in Barrett's metaplasia showing p53 protein accumulation. Am J Gastroenterol (2002) 1.81
Genome-wide DNA methylation profiles in hepatocellular carcinoma. Hepatology (2012) 1.81
Selecting promising ALS therapies in clinical trials. Neurology (2006) 1.80
Heterogeneity of coenzyme Q10 deficiency: patient study and literature review. Arch Neurol (2012) 1.77
Folate and cobalamin deficiencies and hyperhomocysteinemia in Bangladesh. Am J Clin Nutr (2005) 1.74
Impaired carbohydrate digestion and transport and mucosal dysbiosis in the intestines of children with autism and gastrointestinal disturbances. PLoS One (2011) 1.74
The myopathic form of coenzyme Q10 deficiency is caused by mutations in the electron-transferring-flavoprotein dehydrogenase (ETFDH) gene. Brain (2007) 1.73
An observational study of cognitive impairment in amyotrophic lateral sclerosis. Arch Neurol (2006) 1.73
Folic acid supplementation lowers blood arsenic. Am J Clin Nutr (2007) 1.70
Telomere length, oxidative damage, antioxidants and breast cancer risk. Int J Cancer (2009) 1.70
Arsenic exposure from drinking water, dietary intakes of B vitamins and folate, and risk of high blood pressure in Bangladesh: a population-based, cross-sectional study. Am J Epidemiol (2006) 1.66
Parkinsonism genes: culprits and clues. J Neurochem (2006) 1.66
Adaptive immune neuroprotection in G93A-SOD1 amyotrophic lateral sclerosis mice. PLoS One (2008) 1.65
Neural mitochondrial Ca2+ capacity impairment precedes the onset of motor symptoms in G93A Cu/Zn-superoxide dismutase mutant mice. J Neurochem (2006) 1.64
Varying loads of the mitochondrial DNA A3243G mutation in different tissues: implications for diagnosis. Am J Med Genet A (2004) 1.64
Replication and functional genomic analyses of the breast cancer susceptibility locus at 6q25.1 generalize its importance in women of chinese, Japanese, and European ancestry. Cancer Res (2011) 1.59
Heart and skeletal muscle inflammation of farmed salmon is associated with infection with a novel reovirus. PLoS One (2010) 1.58
Altered thymidine metabolism due to defects of thymidine phosphorylase. J Biol Chem (2001) 1.52
Choline metabolism and risk of breast cancer in a population-based study. FASEB J (2008) 1.51
Functional impairment in elderly patients with mild cognitive impairment and mild Alzheimer disease. Arch Gen Psychiatry (2011) 1.50
Telomere length in hepatocellular carcinoma and paired adjacent non-tumor tissues by quantitative PCR. Cancer Invest (2007) 1.50
Environmental toxins and breast cancer on Long Island. II. Organochlorine compound levels in blood. Cancer Epidemiol Biomarkers Prev (2002) 1.50
Efficacy, safety, and tolerability of sertraline in patients with late-life depression and comorbid medical illness. J Am Geriatr Soc (2004) 1.49
Determinants of arsenic metabolism: blood arsenic metabolites, plasma folate, cobalamin, and homocysteine concentrations in maternal-newborn pairs. Environ Health Perspect (2007) 1.49
No association between arsenic exposure from drinking water and diabetes mellitus: a cross-sectional study in Bangladesh. Environ Health Perspect (2010) 1.48
Relationship between urinary 15-F2t-isoprostane and 8-oxodeoxyguanosine levels and breast cancer risk. Cancer Epidemiol Biomarkers Prev (2006) 1.48
Coenzyme Q10 levels are low and associated with increased mortality in post-cardiac arrest patients. Resuscitation (2012) 1.47
Aberrant promoter hypermethylation and genomic hypomethylation in tumor, adjacent normal tissues and blood from breast cancer patients. Anticancer Res (2010) 1.46
Environmental tobacco smoke and breast cancer incidence. Environ Res (2004) 1.45
Folate deficiency, hyperhomocysteinemia, low urinary creatinine, and hypomethylation of leukocyte DNA are risk factors for arsenic-induced skin lesions. Environ Health Perspect (2008) 1.45
Comparison of DNA- and RNA-based methods for detection of truncating BRCA1 mutations. Hum Mutat (2002) 1.44
Improving organochlorine biomarker models for cancer research. Cancer Epidemiol Biomarkers Prev (2005) 1.44
Prenatal exposure to maternal genital and reproductive infections and adult schizophrenia. Am J Psychiatry (2006) 1.44
Association between plasma 25-hydroxyvitamin D and breast cancer risk. Cancer Prev Res (Phila) (2009) 1.44
Atorvastatin decreases the coenzyme Q10 level in the blood of patients at risk for cardiovascular disease and stroke. Arch Neurol (2004) 1.42
A 10-item smell identification scale related to risk for Alzheimer's disease. Ann Neurol (2005) 1.42
Fluorescence in situ hybridization is necessary to detect an association between chromosome aberrations and polycyclic aromatic hydrocarbon exposure in utero and reveals nonrandom chromosome involvement. Environ Mol Mutagen (2007) 1.42
Maternal prenatal urinary phthalate metabolite concentrations and child mental, psychomotor, and behavioral development at 3 years of age. Environ Health Perspect (2011) 1.42
Respiratory chain dysfunction and oxidative stress correlate with severity of primary CoQ10 deficiency. FASEB J (2008) 1.41
Manganese exposure from drinking water and children's academic achievement. Neurotoxicology (2011) 1.41