PubRank

James A Brannigan

Author PubWeight™ 43.71‹?›

Top papers

Rank Title Journal Year PubWeight™‹?›
1 N-myristoyltransferase inhibitors as new leads to treat sleeping sickness. Nature 2010 2.90
2 Crystal structure of dihydrodipicolinate synthase (BA3935) from Bacillus anthracis at 1.94 A resolution. Proteins 2006 1.40
3 Selective inhibitors of protozoan protein N-myristoyltransferases as starting points for tropical disease medicinal chemistry programs. PLoS Negl Trop Dis 2012 1.36
4 The crystal structure of YloQ, a circularly permuted GTPase essential for Bacillus subtilis viability. J Mol Biol 2004 1.29
5 Dimer formation and transcription activation in the sporulation response regulator Spo0A. J Mol Biol 2002 1.27
6 A fluorescence-based assay for N-myristoyltransferase activity. Anal Biochem 2011 1.20
7 The structure of the oligopeptide-binding protein, AppA, from Bacillus subtilis in complex with a nonapeptide. J Mol Biol 2005 1.19
8 An ATP-binding cassette-type cysteine transporter in Campylobacter jejuni inferred from the structure of an extracytoplasmic solute receptor protein. Mol Microbiol 2005 1.16
9 Structural and biochemical characterization of a mitochondrial peroxiredoxin from Plasmodium falciparum. Mol Microbiol 2006 1.14
10 The three-dimensional structure of the N-acetylglucosamine-6-phosphate deacetylase, NagA, from Bacillus subtilis: a member of the urease superfamily. J Biol Chem 2003 1.11
11 Discovery of Plasmodium vivax N-myristoyltransferase inhibitors: screening, synthesis, and structural characterization of their binding mode. J Med Chem 2012 1.09
12 Structure and kinetics of a monomeric glucosamine 6-phosphate deaminase: missing link of the NagB superfamily? J Biol Chem 2005 1.05
13 Structural and functional analysis of a conjugated bile salt hydrolase from Bifidobacterium longum reveals an evolutionary relationship with penicillin V acylase. J Biol Chem 2006 1.04
14 The response regulator Spo0A from Bacillus subtilis is efficiently phosphorylated in Escherichia coli. FEMS Microbiol Lett 2003 1.03
15 Design and synthesis of inhibitors of Plasmodium falciparum N-myristoyltransferase, a promising target for antimalarial drug discovery. J Med Chem 2012 1.03
16 Oligomerization of the Bacillus subtilis division protein DivIVA. Microbiology 2002 1.02
17 The Bacillus subtilis signaling protein SpoIVB defines a new family of serine peptidases. J Bacteriol 2002 0.96
18 Structure-based design of potent and selective Leishmania N-myristoyltransferase inhibitors. J Med Chem 2014 0.95
19 Discovery of novel and ligand-efficient inhibitors of Plasmodium falciparum and Plasmodium vivax N-myristoyltransferase. J Med Chem 2012 0.95
20 Design and synthesis of high affinity inhibitors of Plasmodium falciparum and Plasmodium vivax N-myristoyltransferases directed by ligand efficiency dependent lipophilicity (LELP). J Med Chem 2014 0.95
21 The crystal structures of macrophage migration inhibitory factor from Plasmodium falciparum and Plasmodium berghei. Protein Sci 2009 0.95
22 Multifunctional xylooligosaccharide/cephalosporin C deacetylase revealed by the hexameric structure of the Bacillus subtilis enzyme at 1.9A resolution. J Mol Biol 2003 0.93
23 The structures of Micrococcus lysodeikticus catalase, its ferryl intermediate (compound II) and NADPH complex. Acta Crystallogr D Biol Crystallogr 2002 0.89
24 Structure and non-essential function of glycerol kinase in Plasmodium falciparum blood stages. Mol Microbiol 2008 0.88
25 Peptidomimetic inhibitors of N-myristoyltransferase from human malaria and leishmaniasis parasites. Org Biomol Chem 2014 0.87
26 Cloning, preparation and preliminary crystallographic studies of penicillin V acylase autoproteolytic processing mutants. Acta Crystallogr Sect F Struct Biol Cryst Commun 2004 0.86
27 Crystal structure of PurE (BA0288) from Bacillus anthracis at 1.8 A resolution. Proteins 2005 0.86
28 Structures of two superoxide dismutases from Bacillus anthracis reveal a novel active centre. Acta Crystallogr Sect F Struct Biol Cryst Commun 2005 0.85
29 The orthologue of Sjögren's syndrome nuclear autoantigen 1 (SSNA1) in Trypanosoma brucei is an immunogenic self-assembling molecule. PLoS One 2012 0.85
30 Structures of Plasmodium falciparum purine nucleoside phosphorylase complexed with sulfate and its natural substrate inosine. Acta Crystallogr D Biol Crystallogr 2005 0.85
31 Structural characterization of Spo0E-like protein-aspartic acid phosphatases that regulate sporulation in bacilli. J Biol Chem 2006 0.84
32 Mutations of penicillin acylase residue B71 extend substrate specificity by decreasing steric constraints for substrate binding. Biochem J 2003 0.84
33 Expression, purification, crystallization and preliminary X-ray diffraction analysis of conjugated bile salt hydrolase from Bifidobacterium longum. Acta Crystallogr D Biol Crystallogr 2004 0.84
34 Structure of purine nucleoside phosphorylase (DeoD) from Bacillus anthracis. Acta Crystallogr Sect F Struct Biol Cryst Commun 2005 0.83
35 Detection of picomole amounts of biological substrates by para-hydrogen-enhanced NMR methods in conjunction with a suitable receptor complex. J Am Chem Soc 2007 0.79
36 The crystal structure of superoxide dismutase from Plasmodium falciparum. BMC Struct Biol 2006 0.79
37 Alpha-helix E of Spo0A is required for sigmaA- but not for sigmaH-dependent promoter activation in Bacillus subtilis. J Bacteriol 2004 0.77
38 Synthesis and evaluation of α-thymidine analogues as novel antimalarials. J Med Chem 2012 0.77
39 Structural basis for the efficient phosphorylation of AZT-MP (3'-azido-3'-deoxythymidine monophosphate) and dGMP by Plasmodium falciparum type I thymidylate kinase. Biochem J 2010 0.77
40 Cloning, overexpression, crystallization and preliminary X-ray crystallographic analysis of a slow-processing mutant of penicillin G acylase from Kluyvera citrophila. Acta Crystallogr Sect F Struct Biol Cryst Commun 2013 0.77
41 A mutation in GerE that affects cotC promoter activation in Bacillus subtilis. Biochim Biophys Acta 2002 0.77
42 Crystallization of the oligopeptide-binding protein AppA from Bacillus subtilis. Acta Crystallogr D Biol Crystallogr 2003 0.77
43 Cloning, purification, crystallization and preliminary structural studies of penicillin V acylase from Bacillus subtilis. Acta Crystallogr Sect F Struct Biol Cryst Commun 2005 0.76
44 Design, synthesis, and evaluation of 5'-diphenyl nucleoside analogues as inhibitors of the Plasmodium falciparum dUTPase. ChemMedChem 2011 0.75
45 Purification and characterization of YxeI, a penicillin acylase from Bacillus subtilis. Int J Biol Macromol 2011 0.75
46 Bile salt hydrolase, the member of Ntn-hydrolase family: differential modes of structural and functional transitions during denaturation. IUBMB Life 2007 0.75
47 Crystallization of YloQ, a GTPase of unknown function essential for Bacillus subtilis viability. Acta Crystallogr D Biol Crystallogr 2004 0.75
48 The structure of bypass of forespore C, an intercompartmental signaling factor during sporulation in Bacillus. J Biol Chem 2005 0.75