Published in Am J Physiol Heart Circ Physiol on July 01, 2004
Nitric oxide and peroxynitrite in health and disease. Physiol Rev (2007) 15.49
Measurement of cardiac function using pressure-volume conductance catheter technique in mice and rats. Nat Protoc (2008) 4.50
Role of poly(ADP-ribose) polymerase 1 (PARP-1) in cardiovascular diseases: the therapeutic potential of PARP inhibitors. Cardiovasc Drug Rev (2007) 1.86
Lung injury after hemorrhage is age dependent: role of peroxisome proliferator-activated receptor gamma. Crit Care Med (2009) 1.55
Role of oxidative-nitrosative stress and downstream pathways in various forms of cardiomyopathy and heart failure. Curr Vasc Pharmacol (2005) 1.42
Decreased age-related cardiac dysfunction, myocardial nitrative stress, inflammatory gene expression, and apoptosis in mice lacking fatty acid amide hydrolase. Am J Physiol Heart Circ Physiol (2007) 1.34
Partial nephrectomy as a model for uremic cardiomyopathy in the mouse. Am J Physiol Renal Physiol (2007) 1.31
Role of oxidative and nitrosative stress, longevity genes and poly(ADP-ribose) polymerase in cardiovascular dysfunction associated with aging. Curr Vasc Pharmacol (2005) 1.29
Repair of senescent myocardium by mesenchymal stem cells is dependent on the age of donor mice. J Cell Mol Med (2009) 1.23
Endocannabinoids acting at CB1 receptors mediate the cardiac contractile dysfunction in vivo in cirrhotic rats. Am J Physiol Heart Circ Physiol (2007) 1.22
Beta1-adrenergic receptors stimulate cardiac contractility and CaMKII activation in vivo and enhance cardiac dysfunction following myocardial infarction. Am J Physiol Heart Circ Physiol (2009) 1.17
Altered ventricular torsion and transmural patterns of myocyte relaxation precede heart failure in aging F344 rats. Am J Physiol Heart Circ Physiol (2013) 1.04
Caspase-3 protects stressed organs against cell death. Mol Cell Biol (2012) 1.03
The phosphodiesterase-5 inhibitor vardenafil improves cardiovascular dysfunction in experimental diabetes mellitus. Br J Pharmacol (2009) 0.99
Exercise, vascular stiffness, and tissue transglutaminase. J Am Heart Assoc (2014) 0.93
Measuring regional changes in the diastolic deformation of the left ventricle of SHR rats using microPET technology and hyperelastic warping. Ann Biomed Eng (2008) 0.93
Assessment of contractility in intact ventricular cardiomyocytes using the dimensionless 'Frank-Starling Gain' index. Pflugers Arch (2011) 0.92
Myocardial short-range force responses increase with age in F344 rats. J Mol Cell Cardiol (2008) 0.91
Alagebrium in combination with exercise ameliorates age-associated ventricular and vascular stiffness. Exp Gerontol (2012) 0.90
Single dose treatment with PARP-inhibitor INO-1001 improves aging-associated cardiac and vascular dysfunction. Exp Gerontol (2007) 0.89
Intracardiac injection of matrigel induces stem cell recruitment and improves cardiac functions in a rat myocardial infarction model. J Cell Mol Med (2010) 0.88
Survival, exercise capacity, and left ventricular remodeling in a rat model of chronic mitral regurgitation: serial echocardiography and pressure-volume analysis. Korean Circ J (2011) 0.87
Long-term exercise training attenuates age-related diastolic dysfunction: association of myocardial collagen cross-linking. J Korean Med Sci (2009) 0.87
Adipose-derived cell construct stabilizes heart function and increases microvascular perfusion in an established infarct. Stem Cells Transl Med (2013) 0.87
Cardiac dysfunction in aging conscious rats: altered cardiac cytoskeletal proteins as a potential mechanism. Am J Physiol Heart Circ Physiol (2008) 0.86
Substitution of Brown Norway chromosome 16 preserves cardiac function with aging in a salt-sensitive Dahl consomic rat. Physiol Genomics (2008) 0.86
Mathematical modeling of left ventricular dimensional changes in mice during aging. BMC Syst Biol (2012) 0.85
iPSC-derived human cardiac progenitor cells improve ventricular remodelling via angiogenesis and interstitial networking of infarcted myocardium. J Cell Mol Med (2015) 0.82
Effect of aging on power output properties in rat skinned cardiac myocytes. J Gerontol A Biol Sci Med Sci (2011) 0.82
Cardiac mechanoenergetic cost of elevated plasma viscosity after moderate hemodilution. Biorheology (2010) 0.81
Cardiorenal fibrosis and dysfunction in aging: Imbalance in mediators and regulators of collagen. Peptides (2016) 0.80
Improvement of aging-associated cardiovascular dysfunction by the orally administered copper(II)-aspirinate complex. Rejuvenation Res (2008) 0.79
Exogenous intravascular nitric oxide enhances ventricular function after hemodilution with plasma expander. Life Sci (2011) 0.78
The age dependence of left ventricular filling efficiency. Ultrasound Med Biol (2009) 0.77
Cardiac systolic function recovery after hemorrhage determines survivability during shock. J Trauma (2011) 0.76
Improving cardiac function with new-generation plasma volume expanders. Am J Emerg Med (2012) 0.76
TRC120038, a Novel Dual AT(1)/ET(A) Receptor Blocker for Control of Hypertension, Diabetic Nephropathy, and Cardiomyopathy in ob-ZSF1 Rats. Int J Hypertens (2011) 0.75
Respiratory Effects of Sarafotoxins from the Venom of Different Atractaspis Genus Snake Species. Toxins (Basel) (2016) 0.75
Evaluation of Cardiovascular Risk Factors in the Wistar Audiogenic Rat (WAR) Strain. PLoS One (2015) 0.75
Attenuated sarcomere lengthening of the aged murine left ventricle observed using two-photon fluorescence microscopy. Am J Physiol Heart Circ Physiol (2015) 0.75
Use of pressure-volume conductance catheters in real-time cardiovascular experimentation. Heart Lung Circ (2014) 0.75
Do right-ventricular trabeculae gain energetic advantage from having a greater velocity of shortening? J Physiol (2017) 0.75
Arterial and cardiac aging: major shareholders in cardiovascular disease enterprises: Part II: the aging heart in health: links to heart disease. Circulation (2003) 4.43
Cardiac outcome after peripheral vascular surgery. Comparison of general and regional anesthesia. Anesthesiology (1996) 3.65
Potent metalloporphyrin peroxynitrite decomposition catalyst protects against the development of doxorubicin-induced cardiac dysfunction. Circulation (2003) 2.56
In vivo murine left ventricular pressure-volume relations by miniaturized conductance micromanometry. Am J Physiol (1998) 2.22
The role of poly(ADP-ribose) polymerase activation in the development of myocardial and endothelial dysfunction in diabetes. Diabetes (2002) 2.20
Cardiovascular regulatory mechanisms in advanced age. Physiol Rev (1993) 2.02
Comparative influence of load versus inotropic states on indexes of ventricular contractility: experimental and theoretical analysis based on pressure-volume relationships. Circulation (1987) 1.90
Myocyte cell loss and myocyte cellular hyperplasia in the hypertrophied aging rat heart. Circ Res (1990) 1.89
Transgenic mouse model of stunned myocardium. Science (2000) 1.62
Necrotic and apoptotic myocyte cell death in the aging heart of Fischer 344 rats. Am J Physiol (1996) 1.49
Differences in load dependence of relaxation between the left and right ventricular myocardium as a function of age in rats. Circ Res (1989) 1.47
Parenteral administration of glipizide sodium salt, an inhibitor of adenosine triphosphate-sensitive potassium channels, prolongs short-term survival after severe controlled hemorrhage in rats. Crit Care Med (2003) 1.46
The left ventricular dP/dtmax-end-diastolic volume relation in closed-chest dogs. Circ Res (1985) 1.45
Pharmacologic inhibition of poly(adenosine diphosphate-ribose) polymerase may represent a novel therapeutic approach in chronic heart failure. J Am Coll Cardiol (2002) 1.36
Age-related left ventricular function in the mouse: analysis based on in vivo pressure-volume relationships. Am J Physiol (1999) 1.33
Minimal force-frequency modulation of inotropy and relaxation of in situ murine heart. J Physiol (2001) 1.28
Echocardiographic assessment of age-associated changes in systolic and diastolic function of the female F344 rat heart. J Appl Physiol (1985) (2003) 1.26
Myocardial stiffness derived from end-systolic wall stress and logarithm of reciprocal of wall thickness. Contractility index independent of ventricular size. Circulation (1990) 1.20
Increased systolic performance with diastolic dysfunction in adult spontaneously hypertensive rats. Hypertension (2003) 1.20
Severe myocardial dysfunction induced by ventricular remodeling in aging rat hearts. Am J Physiol (1990) 1.13
Endothelial dysfunction in aging animals: the role of poly(ADP-ribose) polymerase activation. Br J Pharmacol (2002) 1.12
Tumor necrosis factor-alpha from resident lung cells is a key initiating factor in pulmonary ischemia-reperfusion injury. J Thorac Cardiovasc Surg (2004) 1.11
Collagen gene expression in rat left ventricle: interactive effect of age and exercise training. J Appl Physiol (1985) (2000) 1.07
Validation of a mouse conductance system to determine LV volume: comparison to echocardiography and crystals. Am J Physiol Heart Circ Physiol (2000) 1.05
Aging does not affect the activation of the myocyte insulin-like growth factor-1 autocrine system after infarction and ventricular failure in Fischer 344 rats. Circ Res (1996) 1.04
Effects of age on mechanical and structural properties of myocardium of Fischer 344 rats. Am J Physiol (1989) 1.02
Exercise training attenuates aging-associated increases in collagen and collagen crosslinking of the left but not the right ventricle in the rat. Eur J Appl Physiol (2001) 1.01
Individual variation in response to thiopental. Acta Anaesthesiol Scand (1978) 0.96
Computer simulation of the effects of alterations in blood flows and body composition on thiopental pharmacokinetics in humans. Anesthesiology (1997) 0.95
The effect of increasing age on thiopental disposition and anesthetic requirement. Anesthesiology (1985) 0.93
Aging- and training-induced alterations in collagen characteristics of rat left ventricle and papillary muscle. Am J Physiol (1992) 0.93
Effects of aging on quantitative structural properties of coronary vasculature and microvasculature in rats. Am J Physiol (1994) 0.92
The effect of thiopental on peripheral venous tone. Anesthesiology (1961) 0.91
Cellular mechanisms of ventricular failure: myocyte kinetics and geometry with age. Am J Physiol (1992) 0.91
Effects of thiopental on tension development, action potential, and exchange of calcium and potassium in rabbit ventricular myocardium. J Cardiovasc Pharmacol (1981) 0.86
Chronic coronary artery stenosis induces impaired function of remote myocardium: MRI and spectroscopy study in rat. Am J Physiol Heart Circ Physiol (2003) 0.86
Cardiac adaptations to aortic constriction in adult and aged rats. Am J Physiol (1989) 0.82
Age effects on the adaptive response of the female rat heart following aortic constriction. J Gerontol A Biol Sci Med Sci (2000) 0.81
Nitric oxide and peroxynitrite in health and disease. Physiol Rev (2007) 15.49
The therapeutic potential of poly(ADP-ribose) polymerase inhibitors. Pharmacol Rev (2002) 5.92
Poly(ADP-ribose) polymerase and the therapeutic effects of its inhibitors. Nat Rev Drug Discov (2005) 4.61
Therapeutic effects of xanthine oxidase inhibitors: renaissance half a century after the discovery of allopurinol. Pharmacol Rev (2006) 3.27
Early predictors of outcome in comatose survivors of ventricular fibrillation and non-ventricular fibrillation cardiac arrest treated with hypothermia: a prospective study. Crit Care Med (2008) 3.14
Inhibition of GAPDH activity by poly(ADP-ribose) polymerase activates three major pathways of hyperglycemic damage in endothelial cells. J Clin Invest (2003) 2.95
NO-independent stimulators and activators of soluble guanylate cyclase: discovery and therapeutic potential. Nat Rev Drug Discov (2006) 2.84
Simultaneous detection of apoptosis and mitochondrial superoxide production in live cells by flow cytometry and confocal microscopy. Nat Protoc (2007) 2.84
Predictors of awakening from postanoxic status epilepticus after therapeutic hypothermia. Neurology (2009) 2.83
Pharmacological inhibition of CB1 cannabinoid receptor protects against doxorubicin-induced cardiotoxicity. J Am Coll Cardiol (2007) 2.81
Hydrogen sulfide is an endogenous stimulator of angiogenesis. Proc Natl Acad Sci U S A (2009) 2.66
Potent metalloporphyrin peroxynitrite decomposition catalyst protects against the development of doxorubicin-induced cardiac dysfunction. Circulation (2003) 2.56
Simple quantitative detection of mitochondrial superoxide production in live cells. Biochem Biophys Res Commun (2007) 2.51
Soluble guanylate cyclase as an emerging therapeutic target in cardiopulmonary disease. Circulation (2011) 2.48
From evidence to clinical practice: effective implementation of therapeutic hypothermia to improve patient outcome after cardiac arrest. Crit Care Med (2006) 2.48
The role of poly(ADP-ribose) polymerase activation in the development of myocardial and endothelial dysfunction in diabetes. Diabetes (2002) 2.20
CD39 and CD73 in immunity and inflammation. Trends Mol Med (2013) 2.08
Intra-mitochondrial poly(ADP-ribosylation) contributes to NAD+ depletion and cell death induced by oxidative stress. J Biol Chem (2003) 2.04
The vasodilatory response of skin microcirculation to local heating is subject to desensitization. Microcirculation (2009) 2.02
Poly(ADP-ribose) polymerase is involved in the development of diabetic retinopathy via regulation of nuclear factor-kappaB. Diabetes (2004) 2.02
Peroxynitrite is a major trigger of cardiomyocyte apoptosis in vitro and in vivo. Free Radic Biol Med (2006) 1.99
Adenosine augments IL-10 production by macrophages through an A2B receptor-mediated posttranscriptional mechanism. J Immunol (2005) 1.98
Novel phenanthridinone inhibitors of poly (adenosine 5'-diphosphate-ribose) synthetase: potent cytoprotective and antishock agents. Crit Care Med (2002) 1.97
Cannabinoid-2 receptor mediates protection against hepatic ischemia/reperfusion injury. FASEB J (2007) 1.94
Role of superoxide, nitric oxide, and peroxynitrite in doxorubicin-induced cell death in vivo and in vitro. Am J Physiol Heart Circ Physiol (2009) 1.89
Role of poly(ADP-ribose) polymerase 1 (PARP-1) in cardiovascular diseases: the therapeutic potential of PARP inhibitors. Cardiovasc Drug Rev (2007) 1.86
Role of poly(ADP-ribose) polymerase activation in diabetic neuropathy. Diabetes (2004) 1.79
Body temperature regulation and outcome after cardiac arrest and therapeutic hypothermia. Resuscitation (2011) 1.78
CB2-receptor stimulation attenuates TNF-alpha-induced human endothelial cell activation, transendothelial migration of monocytes, and monocyte-endothelial adhesion. Am J Physiol Heart Circ Physiol (2007) 1.77
A2A adenosine receptors and C/EBPbeta are crucially required for IL-10 production by macrophages exposed to Escherichia coli. Blood (2007) 1.76
Role of nitrosative stress and peroxynitrite in the pathogenesis of diabetic complications. Emerging new therapeutical strategies. Curr Med Chem (2005) 1.72
Cardiac and metabolic effects of hypothermia and inhaled hydrogen sulfide in anesthetized and ventilated mice. Crit Care Med (2010) 1.70
Immunity, inflammation and cancer: a leading role for adenosine. Nat Rev Cancer (2013) 1.69
Flagellin from gram-negative bacteria is a potent mediator of acute pulmonary inflammation in sepsis. Shock (2003) 1.64
Role for nitrosative stress in diabetic neuropathy: evidence from studies with a peroxynitrite decomposition catalyst. FASEB J (2004) 1.64
Plasma adenosine concentration increases during exercise: a possible contributing factor in exercise-induced bronchoconstriction in asthma. J Allergy Clin Immunol (2002) 1.59
Effects of intravenous sulfide during resuscitated porcine hemorrhagic shock*. Crit Care Med (2012) 1.58
Cannabidiol attenuates cardiac dysfunction, oxidative stress, fibrosis, and inflammatory and cell death signaling pathways in diabetic cardiomyopathy. J Am Coll Cardiol (2010) 1.56
Cannabidiol attenuates high glucose-induced endothelial cell inflammatory response and barrier disruption. Am J Physiol Heart Circ Physiol (2007) 1.54
Immunomodulatory and neuroprotective effects of inosine. Trends Pharmacol Sci (2004) 1.53
Nitrosative stress and pharmacological modulation of heart failure. Trends Pharmacol Sci (2005) 1.53
Intranuclear localization of apoptosis-inducing factor (AIF) and large scale DNA fragmentation after traumatic brain injury in rats and in neuronal cultures exposed to peroxynitrite. J Neurochem (2002) 1.52
Aldose reductase inhibition counteracts oxidative-nitrosative stress and poly(ADP-ribose) polymerase activation in tissue sites for diabetes complications. Diabetes (2005) 1.49
Investigational A₃ adenosine receptor targeting agents. Expert Opin Investig Drugs (2011) 1.49
Effects of FP15, a peroxynitrite decomposition catalyst on cardiac and pulmonary function after cardiopulmonary bypass. Eur J Cardiothorac Surg (2012) 1.48
The adenosine A3 receptor agonist, N6-(3-iodobenzyl)-adenosine-5'-N-methyluronamide, is protective in two murine models of colitis. Eur J Pharmacol (2003) 1.48
Mesenteric injury after cardiopulmonary bypass: role of poly(adenosine 5'-diphosphate-ribose) polymerase. Crit Care Med (2004) 1.46
Parenteral administration of glipizide sodium salt, an inhibitor of adenosine triphosphate-sensitive potassium channels, prolongs short-term survival after severe controlled hemorrhage in rats. Crit Care Med (2003) 1.46
Clinical perspectives of PARP inhibitors. Pharmacol Res (2005) 1.46
Identification of conserved domains in Salmonella muenchen flagellin that are essential for its ability to activate TLR5 and to induce an inflammatory response in vitro. J Biol Chem (2003) 1.46
Peroxynitrite-induced cytotoxicity: mechanism and opportunities for intervention. Toxicol Lett (2003) 1.45
Resistance to acute septic peritonitis in poly(ADP-ribose) polymerase-1-deficient mice. Shock (2002) 1.44
Poly-ADP-ribose polymerase inhibition protects against myocardial and endothelial reperfusion injury after hypothermic cardiac arrest. J Thorac Cardiovasc Surg (2003) 1.44
Adenosine A2A receptor inactivation increases survival in polymicrobial sepsis. J Immunol (2006) 1.43
Sepsis up-regulates the expression of connexin 40 in rat aortic endothelium. Crit Care Med (2005) 1.40
Cannabinoid-2 receptor agonist HU-308 protects against hepatic ischemia/reperfusion injury by attenuating oxidative stress, inflammatory response, and apoptosis. J Leukoc Biol (2007) 1.39
Pulse wave analysis of aortic pressure: diastole should also be considered. J Hypertens (2013) 1.39
Adenosine promotes alternative macrophage activation via A2A and A2B receptors. FASEB J (2011) 1.38
Cannabinoid-2 receptor limits inflammation, oxidative/nitrosative stress, and cell death in nephropathy. Free Radic Biol Med (2009) 1.38
Gender differences in the endotoxin-induced inflammatory and vascular responses: potential role of poly(ADP-ribose) polymerase activation. J Pharmacol Exp Ther (2005) 1.37
Pharmacologic inhibition of poly(adenosine diphosphate-ribose) polymerase may represent a novel therapeutic approach in chronic heart failure. J Am Coll Cardiol (2002) 1.36
Decreased age-related cardiac dysfunction, myocardial nitrative stress, inflammatory gene expression, and apoptosis in mice lacking fatty acid amide hydrolase. Am J Physiol Heart Circ Physiol (2007) 1.34
Role of peroxynitrite in the pathogenesis of cardiovascular complications of diabetes. Curr Opin Pharmacol (2006) 1.34
A2B adenosine receptors protect against sepsis-induced mortality by dampening excessive inflammation. J Immunol (2010) 1.33
Protective effect of a novel, potent inhibitor of poly(adenosine 5'-diphosphate-ribose) synthetase in a porcine model of severe bacterial sepsis. Crit Care Med (2002) 1.32
Effect of poly(ADP ribose) synthetase inhibition on burn and smoke inhalation injury in sheep. Am J Physiol Lung Cell Mol Physiol (2003) 1.32
A new, potent poly(ADP-ribose) polymerase inhibitor improves cardiac and vascular dysfunction associated with advanced aging. J Pharmacol Exp Ther (2004) 1.32