Published in Neurochem Int on October 01, 2004
Neuroprotection by adenosine in the brain: From A(1) receptor activation to A (2A) receptor blockade. Purinergic Signal (2005) 1.58
In vivo evaluation of [(11)C]preladenant positron emission tomography for quantification of adenosine A2A receptors in the rat brain. J Cereb Blood Flow Metab (2016) 0.75
Presynaptic control of striatal glutamatergic neurotransmission by adenosine A1-A2A receptor heteromers. J Neurosci (2006) 2.29
Adenosine A2A receptors are essential for long-term potentiation of NMDA-EPSCs at hippocampal mossy fiber synapses. Neuron (2008) 2.09
Adenosine and brain function. Int Rev Neurobiol (2005) 1.97
Mitochondria dysfunction of Alzheimer's disease cybrids enhances Abeta toxicity. J Neurochem (2004) 1.58
Ubiquitin proteasome system in Parkinson's disease: a keeper or a witness? Exp Neurol (2012) 1.50
Neuroinflammation, oxidative stress and the pathogenesis of Alzheimer's disease. Curr Pharm Des (2010) 1.50
Adenosine receptor antagonists including caffeine alter fetal brain development in mice. Sci Transl Med (2013) 1.46
Mitochondrial dysfunction and reactive oxygen species in excitotoxicity and apoptosis: implications for the pathogenesis of neurodegenerative diseases. Neurochem Res (2003) 1.34
Insulin in central nervous system: more than just a peripheral hormone. J Aging Res (2012) 1.33
Adenosine receptors and brain diseases: neuroprotection and neurodegeneration. Biochim Biophys Acta (2010) 1.32
Cytochrome c oxidase is decreased in Alzheimer's disease platelets. Neurobiol Aging (2004) 1.30
Dual presynaptic control by ATP of glutamate release via facilitatory P2X1, P2X2/3, and P2X3 and inhibitory P2Y1, P2Y2, and/or P2Y4 receptors in the rat hippocampus. J Neurosci (2005) 1.29
A critical role of the adenosine A2A receptor in extrastriatal neurons in modulating psychomotor activity as revealed by opposite phenotypes of striatum and forebrain A2A receptor knock-outs. J Neurosci (2008) 1.27
Involvement of cannabinoid receptors in the regulation of neurotransmitter release in the rodent striatum: a combined immunochemical and pharmacological analysis. J Neurosci (2005) 1.26
Adenosine A2A receptor antagonists exert motor and neuroprotective effects by distinct cellular mechanisms. Ann Neurol (2008) 1.24
Caffeine and adenosine A(2a) receptor antagonists prevent beta-amyloid (25-35)-induced cognitive deficits in mice. Exp Neurol (2006) 1.23
Adenosine A2A receptor blockade prevents synaptotoxicity and memory dysfunction caused by beta-amyloid peptides via p38 mitogen-activated protein kinase pathway. J Neurosci (2009) 1.23
Adenosine receptor heteromers and their integrative role in striatal function. ScientificWorldJournal (2007) 1.22
Modulator effects of interleukin-1beta and tumor necrosis factor-alpha on AMPA-induced excitotoxicity in mouse organotypic hippocampal slice cultures. J Neurosci (2005) 1.19
Mitochondrial-dependent Ca2+ handling in Huntington's disease striatal cells: effect of histone deacetylase inhibitors. J Neurosci (2006) 1.19
Lipoic acid and N-acetyl cysteine decrease mitochondrial-related oxidative stress in Alzheimer disease patient fibroblasts. J Alzheimers Dis (2007) 1.19
Autophagocytosis of mitochondria is prominent in Alzheimer disease. J Neuropathol Exp Neurol (2007) 1.18
An endoplasmic-reticulum-specific apoptotic pathway is involved in prion and amyloid-beta peptides neurotoxicity. Neurobiol Dis (2006) 1.17
CXCL12/CXCR4 promotes motility and proliferation of glioma cells. Cancer Biol Ther (2010) 1.17
Key modulatory role of presynaptic adenosine A2A receptors in cortical neurotransmission to the striatal direct pathway. ScientificWorldJournal (2009) 1.16
Alzheimer disease and the role of free radicals in the pathogenesis of the disease. CNS Neurol Disord Drug Targets (2008) 1.15
Adenosine A2A receptors control neuroinflammation and consequent hippocampal neuronal dysfunction. J Neurochem (2011) 1.15
Increased autophagic degradation of mitochondria in Alzheimer disease. Autophagy (2007) 1.14
Co-localization and functional interaction between adenosine A(2A) and metabotropic group 5 receptors in glutamatergic nerve terminals of the rat striatum. J Neurochem (2005) 1.11
Cellular and molecular mechanisms involved in the neurotoxicity of opioid and psychostimulant drugs. Brain Res Rev (2008) 1.11
Metformin promotes isolated rat liver mitochondria impairment. Mol Cell Biochem (2007) 1.10
The release of calcium from the endoplasmic reticulum induced by amyloid-beta and prion peptides activates the mitochondrial apoptotic pathway. Neurobiol Dis (2008) 1.09
An integrative view of the role of oxidative stress, mitochondria and insulin in Alzheimer's disease. J Alzheimers Dis (2009) 1.08
Morphological alterations induced by doxorubicin on H9c2 myoblasts: nuclear, mitochondrial, and cytoskeletal targets. Cell Biol Toxicol (2008) 1.08
Oxidative stress involvement in alpha-synuclein oligomerization in Parkinson's disease cybrids. Antioxid Redox Signal (2009) 1.08
Brain mitochondrial dysfunction as a link between Alzheimer's disease and diabetes. J Neurol Sci (2007) 1.07
Mitochondrial function in Parkinson's disease cybrids containing an nt2 neuron-like nuclear background. Mitochondrion (2008) 1.07
Mechanisms of action of metformin in type 2 diabetes and associated complications: an overview. Mini Rev Med Chem (2008) 1.07
Decrease of adenosine A1 receptor density and of adenosine neuromodulation in the hippocampus of kindled rats. Eur J Neurosci (2003) 1.06
Differential glutamate-dependent and glutamate-independent adenosine A1 receptor-mediated modulation of dopamine release in different striatal compartments. J Neurochem (2007) 1.05
Tamoxifen and estradiol interact with the flavin mononucleotide site of complex I leading to mitochondrial failure. J Biol Chem (2006) 1.05
Overactivation of calcineurin induced by amyloid-beta and prion proteins. Neurochem Int (2008) 1.04
Pharmacology of adenosine A2A receptors and therapeutic applications. Curr Top Med Chem (2003) 1.04
Insulin restores metabolic function in cultured cortical neurons subjected to oxidative stress. Diabetes (2006) 1.04
Insulin signaling, glucose metabolism and mitochondria: major players in Alzheimer's disease and diabetes interrelation. Brain Res (2012) 1.04
Cholesterol and statins in Alzheimer's disease: current controversies. Exp Neurol (2009) 1.03
Alzheimer's disease: a lesson from mitochondrial dysfunction. Antioxid Redox Signal (2007) 1.02
Metformin protects the brain against the oxidative imbalance promoted by type 2 diabetes. Med Chem (2008) 1.01
Neuroprotection by caffeine and adenosine A2A receptor blockade of beta-amyloid neurotoxicity. Br J Pharmacol (2003) 1.01
Pre-synaptic adenosine A2A receptors control cannabinoid CB1 receptor-mediated inhibition of striatal glutamatergic neurotransmission. J Neurochem (2010) 0.99
Blood oxidative stress markers in non-alcoholic steatohepatitis and how it correlates with diet. Scand J Gastroenterol (2008) 0.99
Cytosolic and mitochondrial ROS in staurosporine-induced retinal cell apoptosis. Free Radic Biol Med (2003) 0.99
Alzheimer-specific epitopes of tau represent lipid peroxidation-induced conformations. Free Radic Biol Med (2005) 0.98
Increased vulnerability of brain mitochondria in diabetic (Goto-Kakizaki) rats with aging and amyloid-beta exposure. Diabetes (2003) 0.98
Induction of cytochrome c-mediated apoptosis by amyloid beta 25-35 requires functional mitochondria. Brain Res (2002) 0.98
Involvement of endoplasmic reticulum Ca2+ release through ryanodine and inositol 1,4,5-triphosphate receptors in the neurotoxic effects induced by the amyloid-beta peptide. J Neurosci Res (2004) 0.98
Blockade of adenosine A(2A) receptors prevents staurosporine-induced apoptosis of rat hippocampal neurons. Neurobiol Dis (2007) 0.97
Caffeine consumption attenuates neurochemical modifications in the hippocampus of streptozotocin-induced diabetic rats. J Neurochem (2009) 0.97
Dysfunctional mitochondria uphold calpain activation: contribution to Parkinson's disease pathology. Neurobiol Dis (2009) 0.97
Endoplasmic reticulum and mitochondria interplay mediates apoptotic cell death: relevance to Parkinson's disease. Neurochem Int (2009) 0.96
Epigenetics in neurodegeneration: a new layer of complexity. Prog Neuropsychopharmacol Biol Psychiatry (2010) 0.96
Caffeine consumption prevents diabetes-induced memory impairment and synaptotoxicity in the hippocampus of NONcZNO10/LTJ mice. PLoS One (2012) 0.96
Subcellular localization of adenosine A(1) receptors in nerve terminals and synapses of the rat hippocampus. Brain Res (2003) 0.96
Adenosine A3 receptors are located in neurons of the rat hippocampus. Neuroreport (2003) 0.95
Activation of microglial cells triggers a release of brain-derived neurotrophic factor (BDNF) inducing their proliferation in an adenosine A2A receptor-dependent manner: A2A receptor blockade prevents BDNF release and proliferation of microglia. J Neuroinflammation (2013) 0.95
FK506 prevents mitochondrial-dependent apoptotic cell death induced by 3-nitropropionic acid in rat primary cortical cultures. Neurobiol Dis (2004) 0.94
Neurodegeneration in an Abeta-induced model of Alzheimer's disease: the role of Cdk5. Aging Cell (2009) 0.94
Cdk5 acts as a mediator of neuronal cell cycle re-entry triggered by amyloid-beta and prion peptides. Cell Cycle (2009) 0.94
Binding of the prototypical adenosine A(2A) receptor agonist CGS 21680 to the cerebral cortex of adenosine A(1) and A(2A) receptor knockout mice. Br J Pharmacol (2004) 0.94
Oxidative stress: the old enemy in Alzheimer's disease pathophysiology. Curr Alzheimer Res (2005) 0.93
Endoplasmic reticulum stress occurs downstream of GluN2B subunit of N-methyl-d-aspartate receptor in mature hippocampal cultures treated with amyloid-β oligomers. Aging Cell (2012) 0.93
Effects of estrogen in the brain: is it a neuroprotective agent in Alzheimer's disease? Curr Aging Sci (2010) 0.93
Lack of evidence for functional TRPV1 vanilloid receptors in rat hippocampal nerve terminals. Neurosci Lett (2006) 0.93
Adenosine A2A receptors modulate glutamate uptake in cultured astrocytes and gliosomes. Glia (2012) 0.93
Role of cyclin-dependent kinase 5 in the neurodegenerative process triggered by amyloid-Beta and prion peptides: implications for Alzheimer's disease and prion-related encephalopathies. Cell Mol Neurobiol (2007) 0.92
GABA release by basket cells onto Purkinje cells, in rat cerebellar slices, is directly controlled by presynaptic purinergic receptors, modulating Ca2+ influx. Cell Calcium (2008) 0.92
Long-term effect of convulsive behavior on the density of adenosine A1 and A 2A receptors in the rat cerebral cortex. Epilepsia (2005) 0.92
Microtubule depolymerization potentiates alpha-synuclein oligomerization. Front Aging Neurosci (2010) 0.92
Insulin is a two-edged knife on the brain. J Alzheimers Dis (2009) 0.92
Insulin neuroprotection against oxidative stress is mediated by Akt and GSK-3beta signaling pathways and changes in protein expression. Biochim Biophys Acta (2008) 0.91
ER-mediated stress induces mitochondrial-dependent caspases activation in NT2 neuron-like cells. BMB Rep (2009) 0.91
Mitochondrial metabolism in Parkinson's disease impairs quality control autophagy by hampering microtubule-dependent traffic. Hum Mol Genet (2012) 0.91
Ecto-5'-nucleotidase (CD73)-mediated formation of adenosine is critical for the striatal adenosine A2A receptor functions. J Neurosci (2013) 0.91
Amyloid-β-induced mitochondrial dysfunction impairs the autophagic lysosomal pathway in a tubulin dependent pathway. J Alzheimers Dis (2011) 0.90
Enhanced role of adenosine A(2A) receptors in the modulation of LTP in the rat hippocampus upon ageing. Eur J Neurosci (2011) 0.90
GDNF control of the glutamatergic cortico-striatal pathway requires tonic activation of adenosine A receptors. J Neurochem (2009) 0.90
Metabolic alterations induced by sucrose intake and Alzheimer's disease promote similar brain mitochondrial abnormalities. Diabetes (2012) 0.89
Doxorubicin-induced mitochondrial dysfunction is secondary to nuclear p53 activation in H9c2 cardiomyoblasts. Cancer Chemother Pharmacol (2009) 0.89
Vital imaging of H9c2 myoblasts exposed to tert-butylhydroperoxide--characterization of morphological features of cell death. BMC Cell Biol (2007) 0.89
CB₁ receptor activation inhibits neuronal and astrocytic intermediary metabolism in the rat hippocampus. Neurochem Int (2011) 0.89
CB1 receptor antagonism increases hippocampal acetylcholine release: site and mechanism of action. Mol Pharmacol (2006) 0.89