A role for Drosophila IAP1-mediated caspase inhibition in Rac-dependent cell migration.

PubWeight™: 1.69‹?› | Rank: Top 3%

🔗 View Article (PMID 15242648)

Published in Cell on July 09, 2004

Authors

Erika R Geisbrecht1, Denise J Montell

Author Affiliations

1: Department of Biological Chemistry, Johns Hopkins School of Medicine, 725 N. Wolfe Street, Baltimore, MD 21205, USA.

Articles citing this

IAPs: what's in a name? Mol Cell (2008) 3.66

IAP regulation of metastasis. Cancer Cell (2010) 2.47

Light-mediated activation reveals a key role for Rac in collective guidance of cell movement in vivo. Nat Cell Biol (2010) 2.45

The CARD-carrying caspase Dronc is essential for most, but not all, developmental cell death in Drosophila. Development (2005) 2.19

The Jekyll and Hyde functions of caspases. Dev Cell (2009) 1.87

Mechanical feedback through E-cadherin promotes direction sensing during collective cell migration. Cell (2014) 1.76

Corpse Engulfment Generates a Molecular Memory that Primes the Macrophage Inflammatory Response. Cell (2016) 1.47

Genetic control of programmed cell death (apoptosis) in Drosophila. Fly (Austin) (2009) 1.42

IAPs regulate the plasticity of cell migration by directly targeting Rac1 for degradation. EMBO J (2011) 1.36

Drosophila ELMO/CED-12 interacts with Myoblast city to direct myoblast fusion and ommatidial organization. Dev Biol (2007) 1.31

Metacaspase Yca1 is required for clearance of insoluble protein aggregates. Proc Natl Acad Sci U S A (2010) 1.30

Rac1 drives melanoblast organization during mouse development by orchestrating pseudopod- driven motility and cell-cycle progression. Dev Cell (2011) 1.29

The role of apoptosis-induced proliferation for regeneration and cancer. Cold Spring Harb Perspect Biol (2012) 1.28

Group choreography: mechanisms orchestrating the collective movement of border cells. Nat Rev Mol Cell Biol (2012) 1.25

Border-cell migration requires integration of spatial and temporal signals by the BTB protein Abrupt. Nat Cell Biol (2009) 1.25

Physiological functions of caspases beyond cell death. Am J Pathol (2006) 1.22

Mechanisms of nitric oxide interplay with Rho GTPase family members in modulation of actin membrane dynamics in pericytes and fibroblasts. Am J Pathol (2005) 1.22

Inhibitor of apoptosis proteins in eukaryotic evolution and development: a model of thematic conservation. Dev Cell (2008) 1.21

Basolateral junctions utilize warts signaling to control epithelial-mesenchymal transition and proliferation crucial for migration and invasion of Drosophila ovarian epithelial cells. Genetics (2008) 1.21

Drosophila caspase transduces Shaggy/GSK-3beta kinase activity in neural precursor development. EMBO J (2005) 1.14

Spatial restriction of receptor tyrosine kinase activity through a polarized endocytic cycle controls border cell migration. Proc Natl Acad Sci U S A (2010) 1.13

Guidance molecules in axon pruning and cell death. Cold Spring Harb Perspect Biol (2010) 1.13

Survivin - The inconvenient IAP. Semin Cell Dev Biol (2015) 1.04

IAPs on the move: role of inhibitors of apoptosis proteins in cell migration. Cell Death Dis (2013) 1.01

Temporal regulation of Drosophila IAP1 determines caspase functions in sensory organ development. J Cell Biol (2009) 1.01

Pathways regulating apoptosis during patterning and development. Curr Opin Genet Dev (2007) 0.98

Cell behaviors regulated by guidance cues in collective migration of border cells. J Cell Biol (2011) 0.97

A sensitized PiggyBac-based screen for regulators of border cell migration in Drosophila. Genetics (2007) 0.92

Survivin promotes oxidative phosphorylation, subcellular mitochondrial repositioning, and tumor cell invasion. Sci Signal (2015) 0.92

Proteolytic fragmentation of inositol 1,4,5-trisphosphate receptors: a novel mechanism regulating channel activity? J Physiol (2015) 0.90

Bursicon signaling mutations separate the epithelial-mesenchymal transition from programmed cell death during Drosophila melanogaster wing maturation. Genetics (2008) 0.90

How dietary arachidonic- and docosahexaenoic- acid rich oils differentially affect the murine hepatic transcriptome. Lipids Health Dis (2006) 0.89

Psidin, a conserved protein that regulates protrusion dynamics and cell migration. Genes Dev (2011) 0.89

Cell survival and polarity of Drosophila follicle cells require the activity of ecdysone receptor B1 isoform. Genetics (2008) 0.87

The core and conserved role of MAL is homeostatic regulation of actin levels. Genes Dev (2014) 0.86

Transcriptional regulation of Profilin during wound closure in Drosophila larvae. J Cell Sci (2012) 0.86

Microtubules and Lis-1/NudE/dynein regulate invasive cell-on-cell migration in Drosophila. PLoS One (2012) 0.84

Blocking apoptotic signaling rescues axon guidance in Netrin mutants. Cell Rep (2013) 0.83

Genetic interaction screens identify a role for hedgehog signaling in Drosophila border cell migration. Dev Dyn (2013) 0.83

Dronc caspase exerts a non-apoptotic function to restrain phospho-Numb-induced ectopic neuroblast formation in Drosophila. Development (2011) 0.83

GMF promotes leading-edge dynamics and collective cell migration in vivo. Curr Biol (2014) 0.83

Two distinct but convergent groups of cells trigger Torso receptor tyrosine kinase activation by independently expressing torso-like. Proc Natl Acad Sci U S A (2007) 0.82

Tango7 directs cellular remodeling by the Drosophila apoptosome. Genes Dev (2013) 0.82

Detecting caspase activity in Drosophila larval imaginal discs. Methods Mol Biol (2014) 0.81

IAPs as E3 ligases of Rac1: shaping the move. Small GTPases (2012) 0.79

The role of the RING-finger protein Elfless in Drosophila spermatogenesis and apoptosis. Fly (Austin) (2008) 0.79

Ubiquitin-mediated regulation of RhoGTPase signalling: IAPs and HACE1 enter the fray. EMBO J (2012) 0.78

Modeling the Transitions between Collective and Solitary Migration Phenotypes in Cancer Metastasis. Sci Rep (2015) 0.78

Wallenda regulates JNK-mediated cell death in Drosophila. Cell Death Dis (2015) 0.78

Fine-Tuning of the Actin Cytoskeleton and Cell Adhesion During Drosophila Development by the Unconventional Guanine Nucleotide Exchange Factors Myoblast City and Sponge. Genetics (2015) 0.77

Caspase-dependent non-apoptotic processes in development. Cell Death Differ (2017) 0.76

The unconventional myosin CRINKLED and its mammalian orthologue MYO7A regulate caspases in their signalling roles. Nat Commun (2016) 0.76

Niche signaling promotes stem cell survival in the Drosophila testis via the JAK-STAT target DIAP1. Dev Biol (2015) 0.75

Regulation of Cell Death by IAPs and Their Antagonists. Curr Top Dev Biol (2015) 0.75

IKK epsilon signaling: not just NF-kappaB. Curr Biol (2006) 0.75

Non-canonical roles for Yorkie and Drosophila Inhibitor of Apoptosis 1 in epithelial tube size control. PLoS One (2014) 0.75

Articles by these authors

Ovarian cancer metastasis: integrating insights from disparate model organisms. Nat Rev Cancer (2005) 3.20

Light-mediated activation reveals a key role for Rac in collective guidance of cell movement in vivo. Nat Cell Biol (2010) 2.45

Myosin VI is required for E-cadherin-mediated border cell migration. Nat Cell Biol (2002) 2.25

Activated signal transducer and activator of transcription (STAT) 3: localization in focal adhesions and function in ovarian cancer cell motility. Cancer Res (2004) 2.24

Tissue elongation requires oscillating contractions of a basal actomyosin network. Nat Cell Biol (2010) 2.15

Cellular and molecular mechanisms of border cell migration analyzed using time-lapse live-cell imaging. Dev Cell (2007) 2.09

A protocol for culturing Drosophila melanogaster stage 9 egg chambers for live imaging. Nat Protoc (2007) 1.81

Analysis of cell migration using whole-genome expression profiling of migratory cells in the Drosophila ovary. Dev Cell (2006) 1.73

Requirement for JAK/STAT signaling throughout border cell migration in Drosophila. Development (2005) 1.35

PVF1, a PDGF/VEGF homolog, is sufficient to guide border cells and interacts genetically with Taiman. Development (2003) 1.35

Multiple EGFR ligands participate in guiding migrating border cells. Dev Biol (2006) 1.33

Requirement for Par-6 and Bazooka in Drosophila border cell migration. Development (2004) 1.26

Cell survival, DNA damage, and oncogenic transformation after a transient and reversible apoptotic response. Mol Biol Cell (2012) 1.25

Rab11 regulates cell-cell communication during collective cell movements. Nat Cell Biol (2013) 1.19

Feedback inhibition of Jak/STAT signaling by apontic is required to limit an invasive cell population. Dev Cell (2008) 1.11

Enabled and Capping protein play important roles in shaping cell behavior during Drosophila oogenesis. Dev Biol (2009) 1.10

Cellular and molecular mechanisms of single and collective cell migrations in Drosophila: themes and variations. Annu Rev Genet (2014) 1.00

PAR-1 kinase regulates epithelial detachment and directional protrusion of migrating border cells. Curr Biol (2008) 0.98

Castor is required for Hedgehog-dependent cell-fate specification and follicle stem cell maintenance in Drosophila oogenesis. Proc Natl Acad Sci U S A (2013) 0.98

Shining light on Drosophila oogenesis: live imaging of egg development. Curr Opin Genet Dev (2011) 0.98

miRNA-mediated feedback inhibition of JAK/STAT morphogen signalling establishes a cell fate threshold. Nat Cell Biol (2011) 0.98

Analysis of cell migration using Drosophila as a model system. Methods Mol Biol (2005) 0.96

A role for extra macrochaetae downstream of Notch in follicle cell differentiation. Development (2004) 0.95

Modeling migration and metastasis in Drosophila. J Mammary Gland Biol Neoplasia (2007) 0.95

Border cell migration: a model system for live imaging and genetic analysis of collective cell movement. Methods Mol Biol (2011) 0.90

Psidin, a conserved protein that regulates protrusion dynamics and cell migration. Genes Dev (2011) 0.89

Genes that drive invasion and migration in Drosophila. Curr Opin Genet Dev (2004) 0.87

Light activated cell migration in synthetic extracellular matrices. Biomaterials (2012) 0.81

A new trick for Cyclin-Cdk: activation of STAT. Dev Cell (2003) 0.77

Border Cell Migration: A Model System for Live Imaging and Genetic Analysis of Collective Cell Movement. Methods Mol Biol (2015) 0.75

Cell and molecular dynamics: visualizing, measuring, and manipulating the chemistry of life. Pflugers Arch (2013) 0.75