Published in Circulation on July 12, 2004
Heat shock factor-1 knockout enhances cholesterol 7α-hydroxylase (CYP7A1) and multidrug transporter (MDR1) gene expressions to attenuate atherosclerosis. Cardiovasc Res (2016) 1.39
Development of subtype-selective oestrogen receptor-based therapeutics. Nat Rev Drug Discov (2011) 1.39
A proteomic approach to differentiate histologically classified stable and unstable plaques from human carotid arteries. Atherosclerosis (2008) 1.14
Heat shock protein 27 (HSP27): biomarker of disease and therapeutic target. Fibrogenesis Tissue Repair (2012) 1.13
Small heat shock proteins in smooth muscle. Pharmacol Ther (2008) 1.13
Intraplaque haemorrhages as the trigger of plaque vulnerability. Eur Heart J (2011) 1.13
Serum heat shock protein 27 and diabetes complications in the EURODIAB prospective complications study: a novel circulating marker for diabetic neuropathy. Diabetes (2008) 1.11
Heat shock protein 27: its potential role in vascular disease. Int J Exp Pathol (2006) 1.09
Antibody titres to heat shock protein 27 are elevated in patients with acute coronary syndrome. Int J Exp Pathol (2008) 1.08
Extracellular HSP27 acts as a signaling molecule to activate NF-κB in macrophages. Cell Stress Chaperones (2012) 1.06
A proteomic focus on the alterations occurring at the human atherosclerotic coronary intima. Mol Cell Proteomics (2011) 0.90
Proteotoxic stress and circulating cell stress proteins in the cardiovascular diseases. Cell Stress Chaperones (2012) 0.90
Identification of a protective role for protein phosphatase 1cgamma1 against oxidative stress-induced vascular smooth muscle cell apoptosis. J Biol Chem (2008) 0.88
Proteomic analysis permits the identification of new biomarkers of arterial wall remodeling in hypertension. Mol Med (2008) 0.85
Molecular chaperones and heat shock proteins in atherosclerosis. Am J Physiol Heart Circ Physiol (2011) 0.84
Heat shock proteins: pathogenic role in atherosclerosis and potential therapeutic implications. Autoimmune Dis (2012) 0.84
Pediatric Sepsis - Part V: Extracellular Heat Shock Proteins: Alarmins for the Host Immune System. Open Inflamm J (2011) 0.82
Expression of heat shock proteins and nitrotyrosine in small arteries from patients with coronary heart disease. Heart Vessels (2009) 0.81
Proteomic Biomarkers of Atherosclerosis. Biomark Insights (2008) 0.81
Modification of the secretion pattern of proteases, inflammatory mediators, and extracellular matrix proteins by human aortic valve is key in severe aortic stenosis. Mol Cell Proteomics (2013) 0.81
Chronic over-expression of heat shock protein 27 attenuates atherogenesis and enhances plaque remodeling: a combined histological and mechanical assessment of aortic lesions. PLoS One (2013) 0.79
Simvastatin and losartan differentially and synergistically inhibit atherosclerosis in apolipoprotein e(-/-) mice. Korean Circ J (2012) 0.78
Heat shock protein 27 is spatially distributed in the human placenta and decreased during labor. PLoS One (2013) 0.77
Heat shock protein-27 delays acute rejection after cardiac transplantation: an experimental model. Transplantation (2014) 0.77
Plasma heat shock protein 27 is associated with coronary artery disease, abdominal aortic aneurysm and peripheral artery disease. Springerplus (2014) 0.77
Extracellular Release and Signaling by Heat Shock Protein 27: Role in Modifying Vascular Inflammation. Front Immunol (2016) 0.76
Applications of Two-Dimensional Electrophoresis Technology to the Study of Atherosclerosis. EJIFCC (2008) 0.75
Cooling the fire of atherosclerosis with heat shock protein 27. J Am Coll Cardiol (2013) 0.75
Novel network biomarkers profile based coronary artery disease risk stratification in Asian Indians. Adv Biomed Res (2013) 0.75
HSP27 Inhibits Homocysteine-Induced Endothelial Apoptosis by Modulation of ROS Production and Mitochondrial Caspase-Dependent Apoptotic Pathway. Biomed Res Int (2016) 0.75
Increased expression of phosphorylated forms of heat-shock protein-27 and p38MAPK in macrophage-rich regions of fibro-fatty atherosclerotic lesions in the rabbit. Int J Exp Pathol (2016) 0.75
Development of human protein reference database as an initial platform for approaching systems biology in humans. Genome Res (2003) 14.79
Highly selective enrichment of phosphorylated peptides from peptide mixtures using titanium dioxide microcolumns. Mol Cell Proteomics (2005) 6.34
Quantifying the evolutionary dynamics of language. Nature (2007) 6.12
Proteomic analysis of post-translational modifications. Nat Biotechnol (2003) 5.87
Quantitative phosphoproteomics applied to the yeast pheromone signaling pathway. Mol Cell Proteomics (2005) 5.07
Parallel bacterial evolution within multiple patients identifies candidate pathogenicity genes. Nat Genet (2011) 4.81
Human Proteinpedia enables sharing of human protein data. Nat Biotechnol (2008) 4.21
Analysis of protein phosphorylation using mass spectrometry: deciphering the phosphoproteome. Trends Biotechnol (2002) 3.85
Mutations in myosin heavy chain 11 cause a syndrome associating thoracic aortic aneurysm/aortic dissection and patent ductus arteriosus. Nat Genet (2006) 3.65
Phosphoproteomics of the Arabidopsis plasma membrane and a new phosphorylation site database. Plant Cell (2004) 3.51
Large-scale analysis of in vivo phosphorylated membrane proteins by immobilized metal ion affinity chromatography and mass spectrometry. Mol Cell Proteomics (2003) 2.98
Prevalence of fabry disease in a cohort of 508 unrelated patients with hypertrophic cardiomyopathy. J Am Coll Cardiol (2007) 2.95
TGF-beta signaling in vascular fibrosis. Cardiovasc Res (2007) 2.86
Evolutionary paths to antibiotic resistance under dynamically sustained drug selection. Nat Genet (2011) 2.86
Highly selective enrichment of phosphorylated peptides using titanium dioxide. Nat Protoc (2006) 2.71
Angiotensin II activates the Smad pathway in vascular smooth muscle cells by a transforming growth factor-beta-independent mechanism. Circulation (2005) 2.55
Biomarkers in cardiovascular medicine. Rev Esp Cardiol (2009) 2.34
The pseudokinase domain of JAK2 is a dual-specificity protein kinase that negatively regulates cytokine signaling. Nat Struct Mol Biol (2011) 2.20
The vascular smooth muscle cell in arterial pathology: a cell that can take on multiple roles. Cardiovasc Res (2012) 2.08
SIMAC (sequential elution from IMAC), a phosphoproteomics strategy for the rapid separation of monophosphorylated from multiply phosphorylated peptides. Mol Cell Proteomics (2007) 1.98
Interleukin-10 deficiency increases atherosclerosis, thrombosis, and low-density lipoproteins in apolipoprotein E knockout mice. Mol Med (2003) 1.95
A specific p47phox -serine phosphorylated by convergent MAPKs mediates neutrophil NADPH oxidase priming at inflammatory sites. J Clin Invest (2006) 1.92
Analytical strategies for phosphoproteomics. Proteomics (2009) 1.85
Fcgamma receptor deficiency confers protection against atherosclerosis in apolipoprotein E knockout mice. Circ Res (2006) 1.81
NF-kappaB activation and overexpression of regulated genes in human diabetic nephropathy. Nephrol Dial Transplant (2004) 1.78
Soluble TWEAK and PTX3 in nondialysis CKD patients: impact on endothelial dysfunction and cardiovascular outcomes. Clin J Am Soc Nephrol (2011) 1.77
Angiotensin II activates the Smad pathway during epithelial mesenchymal transdifferentiation. Kidney Int (2008) 1.77
Angiotensin II: a key factor in the inflammatory and fibrotic response in kidney diseases. Nephrol Dial Transplant (2005) 1.76
Mechanism for activation of the growth factor-activated AGC kinases by turn motif phosphorylation. EMBO J (2007) 1.74
Syndromic and non-syndromic aneurysms of the human ascending aorta share activation of the Smad2 pathway. J Pathol (2009) 1.74
Modification-specific proteomics of plasma membrane proteins: identification and characterization of glycosylphosphatidylinositol-anchored proteins released upon phospholipase D treatment. J Proteome Res (2006) 1.71
Biochemical and functional characterization of the interaction between pentraxin 3 and C1q. Eur J Immunol (2003) 1.67
Modification-specific proteomics: strategies for characterization of post-translational modifications using enrichment techniques. Proteomics (2009) 1.66
Protein hydrogen exchange measured at single-residue resolution by electron transfer dissociation mass spectrometry. Anal Chem (2009) 1.65
Proteomic analysis of glycosylphosphatidylinositol-anchored membrane proteins. Mol Cell Proteomics (2003) 1.65
A CD31-derived peptide prevents angiotensin II-induced atherosclerosis progression and aneurysm formation. Cardiovasc Res (2012) 1.63
Involvement of the mural thrombus as a site of protease release and activation in human aortic aneurysms. Am J Pathol (2002) 1.63
The CD163-expressing macrophages recognize and internalize TWEAK: potential consequences in atherosclerosis. Atherosclerosis (2009) 1.59
Radiolabeled fucoidan as a p-selectin targeting agent for in vivo imaging of platelet-rich thrombus and endothelial activation. J Nucl Med (2011) 1.58
Identification of phosphorylation sites in protein kinase A substrates using artificial neural networks and mass spectrometry. J Proteome Res (2004) 1.57
Autophosphorylation of JAK2 on tyrosines 221 and 570 regulates its activity. Mol Cell Biol (2004) 1.55
Angiotensin II, via AT1 and AT2 receptors and NF-kappaB pathway, regulates the inflammatory response in unilateral ureteral obstruction. J Am Soc Nephrol (2004) 1.55
Dynamic histone H3 epigenome marking during the intraerythrocytic cycle of Plasmodium falciparum. Proc Natl Acad Sci U S A (2009) 1.54
M1 macrophages act as LTβR-independent lymphoid tissue inducer cells during atherosclerosis-related lymphoid neogenesis. Cardiovasc Res (2013) 1.54
(99m)Tc-annexin V and (111)In-antimyosin antibody uptake in experimental myocardial infarction in rats. Eur J Nucl Med Mol Imaging (2005) 1.52
Tumor necrosis factor-like weak inducer of apoptosis (TWEAK) enhances vascular and renal damage induced by hyperlipidemic diet in ApoE-knockout mice. Arterioscler Thromb Vasc Biol (2009) 1.52
Electron transfer dissociation facilitates the measurement of deuterium incorporation into selectively labeled peptides with single residue resolution. J Am Chem Soc (2008) 1.47
Cell cycle-specific UNG2 phosphorylations regulate protein turnover, activity and association with RPA. EMBO J (2007) 1.46
NetPhosYeast: prediction of protein phosphorylation sites in yeast. Bioinformatics (2007) 1.46
Identification of major allergens in watermelon. Int Arch Allergy Immunol (2009) 1.46
The sphingolipid long-chain base-Pkh1/2-Ypk1/2 signaling pathway regulates eisosome assembly and turnover. J Biol Chem (2008) 1.45
Identification of ischemia-regulated phosphorylation sites in connexin43: A possible target for the antiarrhythmic peptide analogue rotigaptide (ZP123). J Mol Cell Cardiol (2006) 1.45
Proteomics in chromatin biology and epigenetics: Elucidation of post-translational modifications of histone proteins by mass spectrometry. J Proteomics (2012) 1.44
Blocking the EP3 receptor for PGE2 with DG-041 decreases thrombosis without impairing haemostatic competence. Cardiovasc Res (2013) 1.43
The cytokine TWEAK modulates renal tubulointerstitial inflammation. J Am Soc Nephrol (2008) 1.43
Evaluation of matrix metalloproteinases in atherosclerosis using a novel noninvasive imaging approach. Arterioscler Thromb Vasc Biol (2008) 1.41
AKI associated with macroscopic glomerular hematuria: clinical and pathophysiologic consequences. Clin J Am Soc Nephrol (2011) 1.40
Anti-inflammatory and immunomodulatory effects of statins. Kidney Int (2003) 1.39
Stable isotope labeling of Arabidopsis thaliana cells and quantitative proteomics by mass spectrometry. Mol Cell Proteomics (2005) 1.39
Renin-angiotensin system activation and interstitial inflammation in human diabetic nephropathy. Kidney Int Suppl (2003) 1.39
Peptide sequencing and characterization of post-translational modifications by enhanced ion-charging and liquid chromatography electron-transfer dissociation tandem mass spectrometry. Anal Chem (2007) 1.35
Transcriptional co-activator protein p100 interacts with snRNP proteins and facilitates the assembly of the spliceosome. Nucleic Acids Res (2007) 1.31
3-Hydroxy-3-methyl-glutaryl coenzyme A reductase inhibitors, atorvastatin and simvastatin, induce apoptosis of vascular smooth muscle cells by downregulation of Bcl-2 expression and Rho A prenylation. Atherosclerosis (2002) 1.31
Global histone analysis by mass spectrometry reveals a high content of acetylated lysine residues in the malaria parasite Plasmodium falciparum. J Proteome Res (2009) 1.30
Collagen is reduced and disrupted in human aneurysms and dissections of ascending aorta. Hum Pathol (2008) 1.30
Extracellular matrix remodelling in human aortic valve disease: the role of matrix metalloproteinases and their tissue inhibitors. Eur Heart J (2005) 1.26
18F-FDG uptake assessed by PET/CT in abdominal aortic aneurysms is associated with cellular and molecular alterations prefacing wall deterioration and rupture. J Nucl Med (2013) 1.26
Renal and vascular hypertension-induced inflammation: role of angiotensin II. Curr Opin Nephrol Hypertens (2006) 1.26
Identification of soluble tumor necrosis factor-like weak inducer of apoptosis (sTWEAK) as a possible biomarker of subclinical atherosclerosis. Arterioscler Thromb Vasc Biol (2007) 1.25
Topological determinants and consequences of adventitial responses to arterial wall injury. Arterioscler Thromb Vasc Biol (2007) 1.25
Heat shock protein 90 inhibitors attenuate inflammatory responses in atherosclerosis. Cardiovasc Res (2010) 1.23
Quantitative mass spectrometry of histones H3.2 and H3.3 in Suz12-deficient mouse embryonic stem cells reveals distinct, dynamic post-translational modifications at Lys-27 and Lys-36. Mol Cell Proteomics (2010) 1.23
VEMS 3.0: algorithms and computational tools for tandem mass spectrometry based identification of post-translational modifications in proteins. J Proteome Res (2005) 1.22
Additive effects of soluble TWEAK and inflammation on mortality in hemodialysis patients. Clin J Am Soc Nephrol (2008) 1.22
Metastasis-related plasma membrane proteins of human breast cancer cells identified by comparative quantitative mass spectrometry. Mol Cell Proteomics (2009) 1.21
Protease nexin-1 inhibits plasminogen activation-induced apoptosis of adherent cells. J Biol Chem (2003) 1.21
Rituximab treatment of adult patients with steroid-resistant focal segmental glomerulosclerosis. Clin J Am Soc Nephrol (2009) 1.21
TRPC6 mutational analysis in a large cohort of patients with focal segmental glomerulosclerosis. Nephrol Dial Transplant (2009) 1.21
Connective tissue growth factor is a mediator of angiotensin II-induced fibrosis. Circulation (2003) 1.21
Molecular mechanisms of angiotensin II-induced vascular injury. Curr Hypertens Rep (2003) 1.20
Faulty initiation of proteoglycan synthesis causes cardiac and joint defects. Am J Hum Genet (2011) 1.20
WAVE regulatory complex activation by cooperating GTPases Arf and Rac1. Proc Natl Acad Sci U S A (2011) 1.20
Involvement of intraplaque hemorrhage in atherothrombosis evolution via neutrophil protease enrichment. J Leukoc Biol (2007) 1.18
Autophosphorylation is essential for the in vivo function of the Lotus japonicus Nod factor receptor 1 and receptor-mediated signalling in cooperation with Nod factor receptor 5. Plant J (2010) 1.17
Biological significance of decreased HSP27 in human atherosclerosis. Arterioscler Thromb Vasc Biol (2006) 1.16