Published in J Neurochem on August 01, 2004
Bile acids: regulation of apoptosis by ursodeoxycholic acid. J Lipid Res (2009) 1.36
TUDCA slows retinal degeneration in two different mouse models of retinitis pigmentosa and prevents obesity in Bardet-Biedl syndrome type 1 mice. Invest Ophthalmol Vis Sci (2012) 1.09
p38 phosphorylates Rb on Ser567 by a novel, cell cycle-independent mechanism that triggers Rb-Hdm2 interaction and apoptosis. Oncogene (2010) 1.06
Tauroursodeoxycholic acid preservation of photoreceptor structure and function in the rd10 mouse through postnatal day 30. Invest Ophthalmol Vis Sci (2008) 1.05
Apoptosis in transgenic mice expressing the P301L mutated form of human tau. Mol Med (2008) 1.03
Tauroursodeoxycholic acid prevents E22Q Alzheimer's Abeta toxicity in human cerebral endothelial cells. Cell Mol Life Sci (2009) 0.96
Expression of hereditary hemochromatosis C282Y HFE protein in HEK293 cells activates specific endoplasmic reticulum stress responses. BMC Cell Biol (2007) 0.86
Repair of oxidative DNA damage, cell-cycle regulation and neuronal death may influence the clinical manifestation of Alzheimer's disease. PLoS One (2014) 0.85
p53 and Cell Cycle Proteins Participate in Spinal Motor Neuron Cell Death in ALS. Open Pathol J (2010) 0.80
Galanin protects against nerve injury after shear stress in primary cultured rat cortical neurons. PLoS One (2013) 0.79
Effects of bile acids on neurological function and disease. FASEB J (2016) 0.75
Molecular mechanisms of hepatocellular carcinoma. Hepatology (2008) 3.51
Hepatocyte apoptosis, expression of death receptors, and activation of NF-kappaB in the liver of nonalcoholic and alcoholic steatohepatitis patients. Am J Gastroenterol (2004) 2.70
PIMS modulates immune tolerance by negatively regulating Drosophila innate immune signaling. Cell Host Microbe (2008) 2.48
Human colon cancer profiles show differential microRNA expression depending on mismatch repair status and are characteristic of undifferentiated proliferative states. BMC Cancer (2009) 2.32
Bilirubin induces apoptosis via the mitochondrial pathway in developing rat brain neurons. Hepatology (2002) 1.96
miRNA expression in colon polyps provides evidence for a multihit model of colon cancer. PLoS One (2011) 1.72
Gene networks and microRNAs implicated in aggressive prostate cancer. Cancer Res (2009) 1.68
miR-34a/SIRT1/p53 is suppressed by ursodeoxycholic acid in the rat liver and activated by disease severity in human non-alcoholic fatty liver disease. J Hepatol (2012) 1.59
MicroRNAs identified in highly purified liver-derived mitochondria may play a role in apoptosis. RNA Biol (2009) 1.55
MicroRNA-143 reduces viability and increases sensitivity to 5-fluorouracil in HCT116 human colorectal cancer cells. FEBS J (2009) 1.54
The role of p53 in apoptosis. Discov Med (2010) 1.46
Double-stranded siRNA targeted to the huntingtin gene does not induce DNA methylation. Biochem Biophys Res Commun (2004) 1.44
Delivering the promise of miRNA cancer therapeutics. Drug Discov Today (2012) 1.43
Cellular and molecular mechanisms of hepatocellular carcinoma: an update. Arch Toxicol (2012) 1.42
Identification of microRNAs during rat liver regeneration after partial hepatectomy and modulation by ursodeoxycholic acid. Am J Physiol Gastrointest Liver Physiol (2010) 1.38
miR-34a regulates mouse neural stem cell differentiation. PLoS One (2011) 1.37
Bile acids: regulation of apoptosis by ursodeoxycholic acid. J Lipid Res (2009) 1.36
Genome-wide transcriptional profiling reveals microRNA-correlated genes and biological processes in human lymphoblastoid cell lines. PLoS One (2009) 1.35
Perturbation of 14q32 miRNAs-cMYC gene network in osteosarcoma. Bone (2011) 1.31
Tauroursodeoxycholic acid, a bile acid, is neuroprotective in a transgenic animal model of Huntington's disease. Proc Natl Acad Sci U S A (2002) 1.29
Tauroursodeoxycholic acid reduces apoptosis and protects against neurological injury after acute hemorrhagic stroke in rats. Proc Natl Acad Sci U S A (2003) 1.27
Heme oxygenase-1 gene delivery by Sleeping Beauty inhibits vascular stasis in a murine model of sickle cell disease. J Mol Med (Berl) (2010) 1.23
miR-143 overexpression impairs growth of human colon carcinoma xenografts in mice with induction of apoptosis and inhibition of proliferation. PLoS One (2011) 1.21
Neuroprotection by a bile acid in an acute stroke model in the rat. J Cereb Blood Flow Metab (2002) 1.19
MicroRNAs as gatekeepers of apoptosis. J Cell Physiol (2010) 1.18
Tool from ancient pharmacopoeia prevents vision loss. Mol Vis (2006) 1.17
Regulation of heme oxygenase-1 protein expression by miR-377 in combination with miR-217. J Biol Chem (2010) 1.16
Apoptosis-associated microRNAs are modulated in mouse, rat and human neural differentiation. BMC Genomics (2010) 1.12
Nanocapsule-delivered Sleeping Beauty mediates therapeutic Factor VIII expression in liver sinusoidal endothelial cells of hemophilia A mice. J Clin Invest (2009) 1.11
A facile method for somatic, lifelong manipulation of multiple genes in the mouse liver. Hepatology (2008) 1.09
Evaluation of a new high-dimensional miRNA profiling platform. BMC Med Genomics (2009) 1.08
Bile acid levels are increased in the liver of patients with steatohepatitis. Eur J Gastroenterol Hepatol (2008) 1.06
c-Jun N-terminal kinase 1/c-Jun activation of the p53/microRNA 34a/sirtuin 1 pathway contributes to apoptosis induced by deoxycholic acid in rat liver. Mol Cell Biol (2014) 1.06
Genomewide microRNA down-regulation as a negative feedback mechanism in the early phases of liver regeneration. Hepatology (2011) 1.05
Efficient mammalian germline transgenesis by cis-enhanced Sleeping Beauty transposition. Transgenic Res (2010) 1.04
Combinatorial treatment of DNA and chromatin-modifying drugs cause cell death in human and canine osteosarcoma cell lines. PLoS One (2012) 1.03
Apoptosis in transgenic mice expressing the P301L mutated form of human tau. Mol Med (2008) 1.03
Ubiquitylation of the initiator caspase DREDD is required for innate immune signalling. EMBO J (2012) 1.03
Bile acids and apoptosis modulation: an emerging role in experimental Alzheimer's disease. Trends Mol Med (2008) 1.03
Mature hepatocytes exhibit unexpected plasticity by direct dedifferentiation into liver progenitor cells in culture. Hepatology (2012) 1.02
TUDCA, a bile acid, attenuates amyloid precursor protein processing and amyloid-β deposition in APP/PS1 mice. Mol Neurobiol (2012) 1.01
Neuronal loss in the rostral ventromedial medulla in a rat model of neuropathic pain. J Neurosci (2011) 1.01
DNA methylation of Sleeping Beauty with transposition into the mouse genome. Genes Cells (2005) 1.01
p53 interaction with JMJD3 results in its nuclear distribution during mouse neural stem cell differentiation. PLoS One (2011) 1.00
Mature microRNAs identified in highly purified nuclei from HCT116 colon cancer cells. RNA Biol (2010) 0.99
p53 is a key molecular target of ursodeoxycholic acid in regulating apoptosis. J Biol Chem (2007) 0.99
Differential regulation of cyclin D1 and cell death by bile acids in primary rat hepatocytes. Am J Physiol Gastrointest Liver Physiol (2007) 0.98
Tauroursodeoxycholic acid modulates p53-mediated apoptosis in Alzheimer's disease mutant neuroblastoma cells. J Neurochem (2006) 0.98
Tauroursodeoxycholic acid improves the survival and function of nigral transplants in a rat model of Parkinson's disease. Cell Transplant (2002) 0.97
Polysome trafficking of transcripts and microRNAs in regenerating liver after partial hepatectomy. Am J Physiol Gastrointest Liver Physiol (2009) 0.97
Inhibition of Fas expression by RNAi modulates 5-fluorouracil-induced apoptosis in HCT116 cells expressing wild-type p53. Biochim Biophys Acta (2006) 0.97
Distinct regulatory functions of calpain 1 and 2 during neural stem cell self-renewal and differentiation. PLoS One (2012) 0.96
Tauroursodeoxycholic acid prevents amyloid-beta peptide-induced neuronal death via a phosphatidylinositol 3-kinase-dependent signaling pathway. Mol Med (2004) 0.96
Sleeping Beauty transposition in the mouse genome is associated with changes in DNA methylation at the site of insertion. Genomics (2006) 0.96
Administration of tauroursodeoxycholic acid (TUDCA) reduces apoptosis following myocardial infarction in rat. Am J Chin Med (2007) 0.95
Tauroursodeoxycholic acid prevents Bax-induced membrane perturbation and cytochrome C release in isolated mitochondria. Biochemistry (2003) 0.95
Rat cultured neuronal and glial cells respond differently to toxicity of unconjugated bilirubin. Pediatr Res (2002) 0.93
Endoplasmic reticulum enrollment in Alzheimer's disease. Mol Neurobiol (2012) 0.93
Targeting the p53 pathway of apoptosis. Curr Pharm Des (2010) 0.92
Efficient recovery of proteins from multiple source samples after TRIzol(®) or TRIzol(®)LS RNA extraction and long-term storage. BMC Genomics (2013) 0.92
Erythroid-specific expression of beta-globin by the sleeping beauty transposon for Sickle cell disease. Biochemistry (2007) 0.92
Apoptosis inducing activity of benzophenanthridine-type alkaloids and 2-arylbenzofuran neolignans in HCT116 colon carcinoma cells. Phytomedicine (2013) 0.91
Dose-dependent differential mRNA target selection and regulation by let-7a-7f and miR-17-92 cluster microRNAs. RNA Biol (2012) 0.91
Inhibition of microRNA-24 expression in liver prevents hepatic lipid accumulation and hyperlipidemia. Hepatology (2014) 0.91
Caspases and p53 modulate FOXO3A/Id1 signaling during mouse neural stem cell differentiation. J Cell Biochem (2009) 0.90