Published in Curr Pharm Des on January 01, 2010
Upregulation of microRNA-451 increases cisplatin sensitivity of non-small cell lung cancer cell line (A549). J Exp Clin Cancer Res (2011) 1.33
p53 interaction with JMJD3 results in its nuclear distribution during mouse neural stem cell differentiation. PLoS One (2011) 1.00
The Unexpected Uses of Urso- and Tauroursodeoxycholic Acid in the Treatment of Non-liver Diseases. Glob Adv Health Med (2014) 0.94
microRNA-106a modulates cisplatin sensitivity by targeting PDCD4 in human ovarian cancer cells. Oncol Lett (2013) 0.91
The up-regulation of histone deacetylase 8 promotes proliferation and inhibits apoptosis in hepatocellular carcinoma. Dig Dis Sci (2013) 0.88
p53 and Ceramide as Collaborators in the Stress Response. Int J Mol Sci (2013) 0.87
Effects of melatonin on the proliferation and apoptosis of sheep granulosa cells under thermal stress. Int J Mol Sci (2014) 0.82
Molecular mechanisms of ursodeoxycholic acid toxicity & side effects: ursodeoxycholic acid freezes regeneration & induces hibernation mode. Int J Mol Sci (2012) 0.81
New Therapeutic Concept of NAD Redox Balance for Cisplatin Nephrotoxicity. Biomed Res Int (2016) 0.79
NAD(+) Metabolism in Age-Related Hearing Loss. Aging Dis (2014) 0.79
Nutlin-3 downregulates p53 phosphorylation on serine392 and induces apoptosis in hepatocellular carcinoma cells. BMB Rep (2014) 0.78
Probing Evolutionary Biography of MicroRNAs and Associated Factors. Curr Genomics (2012) 0.75
Dual anti-ischemic effects of rosmarinic acid n-butyl ester via alleviation of DAPK-p53-mediated neuronal damage and microglial inflammation. Acta Pharmacol Sin (2017) 0.75
Zinc oxide nanoparticles induce apoptosis and autophagy in human ovarian cancer cells. Int J Nanomedicine (2017) 0.75
Molecular mechanisms of hepatocellular carcinoma. Hepatology (2008) 3.51
Hepatocyte apoptosis, expression of death receptors, and activation of NF-kappaB in the liver of nonalcoholic and alcoholic steatohepatitis patients. Am J Gastroenterol (2004) 2.70
Human colon cancer profiles show differential microRNA expression depending on mismatch repair status and are characteristic of undifferentiated proliferative states. BMC Cancer (2009) 2.32
miRNA expression in colon polyps provides evidence for a multihit model of colon cancer. PLoS One (2011) 1.72
Gene networks and microRNAs implicated in aggressive prostate cancer. Cancer Res (2009) 1.68
miR-34a/SIRT1/p53 is suppressed by ursodeoxycholic acid in the rat liver and activated by disease severity in human non-alcoholic fatty liver disease. J Hepatol (2012) 1.59
MicroRNAs identified in highly purified liver-derived mitochondria may play a role in apoptosis. RNA Biol (2009) 1.55
MicroRNA-143 reduces viability and increases sensitivity to 5-fluorouracil in HCT116 human colorectal cancer cells. FEBS J (2009) 1.54
The role of p53 in apoptosis. Discov Med (2010) 1.46
Double-stranded siRNA targeted to the huntingtin gene does not induce DNA methylation. Biochem Biophys Res Commun (2004) 1.44
Delivering the promise of miRNA cancer therapeutics. Drug Discov Today (2012) 1.43
Cellular and molecular mechanisms of hepatocellular carcinoma: an update. Arch Toxicol (2012) 1.42
Identification of microRNAs during rat liver regeneration after partial hepatectomy and modulation by ursodeoxycholic acid. Am J Physiol Gastrointest Liver Physiol (2010) 1.38
miR-34a regulates mouse neural stem cell differentiation. PLoS One (2011) 1.37
Bile acids: regulation of apoptosis by ursodeoxycholic acid. J Lipid Res (2009) 1.36
Genome-wide transcriptional profiling reveals microRNA-correlated genes and biological processes in human lymphoblastoid cell lines. PLoS One (2009) 1.35
Perturbation of 14q32 miRNAs-cMYC gene network in osteosarcoma. Bone (2011) 1.31
Tauroursodeoxycholic acid, a bile acid, is neuroprotective in a transgenic animal model of Huntington's disease. Proc Natl Acad Sci U S A (2002) 1.29
Tauroursodeoxycholic acid reduces apoptosis and protects against neurological injury after acute hemorrhagic stroke in rats. Proc Natl Acad Sci U S A (2003) 1.27
Heme oxygenase-1 gene delivery by Sleeping Beauty inhibits vascular stasis in a murine model of sickle cell disease. J Mol Med (Berl) (2010) 1.23
miR-143 overexpression impairs growth of human colon carcinoma xenografts in mice with induction of apoptosis and inhibition of proliferation. PLoS One (2011) 1.21
Neuroprotection by a bile acid in an acute stroke model in the rat. J Cereb Blood Flow Metab (2002) 1.19
MicroRNAs as gatekeepers of apoptosis. J Cell Physiol (2010) 1.18
Tool from ancient pharmacopoeia prevents vision loss. Mol Vis (2006) 1.17
Regulation of heme oxygenase-1 protein expression by miR-377 in combination with miR-217. J Biol Chem (2010) 1.16
Apoptosis-associated microRNAs are modulated in mouse, rat and human neural differentiation. BMC Genomics (2010) 1.12
Nanocapsule-delivered Sleeping Beauty mediates therapeutic Factor VIII expression in liver sinusoidal endothelial cells of hemophilia A mice. J Clin Invest (2009) 1.11
A facile method for somatic, lifelong manipulation of multiple genes in the mouse liver. Hepatology (2008) 1.09
Evaluation of a new high-dimensional miRNA profiling platform. BMC Med Genomics (2009) 1.08
Kalirin: a novel genetic risk factor for ischemic stroke. Hum Genet (2010) 1.07
Bile acid levels are increased in the liver of patients with steatohepatitis. Eur J Gastroenterol Hepatol (2008) 1.06
c-Jun N-terminal kinase 1/c-Jun activation of the p53/microRNA 34a/sirtuin 1 pathway contributes to apoptosis induced by deoxycholic acid in rat liver. Mol Cell Biol (2014) 1.06
Genomewide microRNA down-regulation as a negative feedback mechanism in the early phases of liver regeneration. Hepatology (2011) 1.05
Efficient mammalian germline transgenesis by cis-enhanced Sleeping Beauty transposition. Transgenic Res (2010) 1.04
Combinatorial treatment of DNA and chromatin-modifying drugs cause cell death in human and canine osteosarcoma cell lines. PLoS One (2012) 1.03
Apoptosis in transgenic mice expressing the P301L mutated form of human tau. Mol Med (2008) 1.03
Bile acids and apoptosis modulation: an emerging role in experimental Alzheimer's disease. Trends Mol Med (2008) 1.03
Mature hepatocytes exhibit unexpected plasticity by direct dedifferentiation into liver progenitor cells in culture. Hepatology (2012) 1.02
TUDCA, a bile acid, attenuates amyloid precursor protein processing and amyloid-β deposition in APP/PS1 mice. Mol Neurobiol (2012) 1.01
DNA methylation of Sleeping Beauty with transposition into the mouse genome. Genes Cells (2005) 1.01
Neuronal loss in the rostral ventromedial medulla in a rat model of neuropathic pain. J Neurosci (2011) 1.01
p53 interaction with JMJD3 results in its nuclear distribution during mouse neural stem cell differentiation. PLoS One (2011) 1.00
Mature microRNAs identified in highly purified nuclei from HCT116 colon cancer cells. RNA Biol (2010) 0.99
p53 is a key molecular target of ursodeoxycholic acid in regulating apoptosis. J Biol Chem (2007) 0.99
Differential regulation of cyclin D1 and cell death by bile acids in primary rat hepatocytes. Am J Physiol Gastrointest Liver Physiol (2007) 0.98
Tauroursodeoxycholic acid modulates p53-mediated apoptosis in Alzheimer's disease mutant neuroblastoma cells. J Neurochem (2006) 0.98
Polysome trafficking of transcripts and microRNAs in regenerating liver after partial hepatectomy. Am J Physiol Gastrointest Liver Physiol (2009) 0.97
Tauroursodeoxycholic acid improves the survival and function of nigral transplants in a rat model of Parkinson's disease. Cell Transplant (2002) 0.97
Inhibition of Fas expression by RNAi modulates 5-fluorouracil-induced apoptosis in HCT116 cells expressing wild-type p53. Biochim Biophys Acta (2006) 0.97
Distinct regulatory functions of calpain 1 and 2 during neural stem cell self-renewal and differentiation. PLoS One (2012) 0.96
Tauroursodeoxycholic acid prevents amyloid-beta peptide-induced neuronal death via a phosphatidylinositol 3-kinase-dependent signaling pathway. Mol Med (2004) 0.96
Sleeping Beauty transposition in the mouse genome is associated with changes in DNA methylation at the site of insertion. Genomics (2006) 0.96
Administration of tauroursodeoxycholic acid (TUDCA) reduces apoptosis following myocardial infarction in rat. Am J Chin Med (2007) 0.95
Tauroursodeoxycholic acid prevents Bax-induced membrane perturbation and cytochrome C release in isolated mitochondria. Biochemistry (2003) 0.95
Endoplasmic reticulum enrollment in Alzheimer's disease. Mol Neurobiol (2012) 0.93
Rat cultured neuronal and glial cells respond differently to toxicity of unconjugated bilirubin. Pediatr Res (2002) 0.93
Erythroid-specific expression of beta-globin by the sleeping beauty transposon for Sickle cell disease. Biochemistry (2007) 0.92
Efficient recovery of proteins from multiple source samples after TRIzol(®) or TRIzol(®)LS RNA extraction and long-term storage. BMC Genomics (2013) 0.92
Apoptosis inducing activity of benzophenanthridine-type alkaloids and 2-arylbenzofuran neolignans in HCT116 colon carcinoma cells. Phytomedicine (2013) 0.91
Dose-dependent differential mRNA target selection and regulation by let-7a-7f and miR-17-92 cluster microRNAs. RNA Biol (2012) 0.91
Inhibition of microRNA-24 expression in liver prevents hepatic lipid accumulation and hyperlipidemia. Hepatology (2014) 0.91
Caspases and p53 modulate FOXO3A/Id1 signaling during mouse neural stem cell differentiation. J Cell Biochem (2009) 0.90
Inhibition of the E2F-1/p53/Bax pathway by tauroursodeoxycholic acid in amyloid beta-peptide-induced apoptosis of PC12 cells. J Neurochem (2004) 0.90
p53 and the regulation of hepatocyte apoptosis: implications for disease pathogenesis. Trends Mol Med (2009) 0.89
Monoterpene bisindole alkaloids, from the African medicinal plant Tabernaemontana elegans, induce apoptosis in HCT116 human colon carcinoma cells. J Ethnopharmacol (2013) 0.89
Ursodeoxycholic acid modulates E2F-1 and p53 expression through a caspase-independent mechanism in transforming growth factor beta1-induced apoptosis of rat hepatocytes. J Biol Chem (2003) 0.89
Sleeping Beauty-mediated down-regulation of huntingtin expression by RNA interference. Biochem Biophys Res Commun (2005) 0.89
One Medicine One Science: a framework for exploring challenges at the intersection of animals, humans, and the environment. Ann N Y Acad Sci (2014) 0.88
Modulation of nuclear steroid receptors by ursodeoxycholic acid inhibits TGF-beta1-induced E2F-1/p53-mediated apoptosis of rat hepatocytes. Biochemistry (2004) 0.88
Apoptosis and Bcl-2 expression in the livers of patients with steatohepatitis. Eur J Gastroenterol Hepatol (2006) 0.88
Stem cell origins and animal models of hepatocellular carcinoma. Dig Dis Sci (2009) 0.87
Death receptors and mitochondria: two prime triggers of neural apoptosis and differentiation. Biochim Biophys Acta (2012) 0.87
Gene repair and transposon-mediated gene therapy. Stem Cells (2002) 0.87
Safety, tolerability, and cerebrospinal fluid penetration of ursodeoxycholic Acid in patients with amyotrophic lateral sclerosis. Clin Neuropharmacol (2010) 0.86
Circulating microRNAs as biomarkers: a new frontier in diagnostics. Liver Transpl (2012) 0.86
Revisiting the metabolic syndrome and paving the way for microRNAs in non-alcoholic fatty liver disease. FEBS J (2014) 0.86
The bile acid tauroursodeoxycholic acid modulates phosphorylation and translocation of bad via phosphatidylinositol 3-kinase in glutamate-induced apoptosis of rat cortical neurons. J Pharmacol Exp Ther (2004) 0.86
MicroRNA-34a Modulates Neural Stem Cell Differentiation by Regulating Expression of Synaptic and Autophagic Proteins. Mol Neurobiol (2014) 0.85