Published in Am J Respir Cell Mol Biol on July 15, 2004
Functions and mechanisms of action of CCN matricellular proteins. Int J Biochem Cell Biol (2008) 3.62
Transforming growth factor-beta and fibrosis. World J Gastroenterol (2007) 2.35
Matricellular proteins in cardiac adaptation and disease. Physiol Rev (2012) 2.01
Procoagulant signalling mechanisms in lung inflammation and fibrosis: novel opportunities for pharmacological intervention? Br J Pharmacol (2008) 1.80
Connective tissue growth factor promotes fibrosis downstream of TGFbeta and IL-6 in chronic cardiac allograft rejection. Am J Transplant (2009) 1.59
Smad3-dependent CCN2 mediates fibronectin expression in human skin dermal fibroblasts. PLoS One (2017) 1.39
Epithelial-mesenchymal transition in primary human bronchial epithelial cells is Smad-dependent and enhanced by fibronectin and TNF-alpha. Fibrogenesis Tissue Repair (2010) 1.37
Connective tissue growth factor (CCN2, CTGF) and organ fibrosis: lessons from transgenic animals. J Cell Commun Signal (2009) 1.30
Complex regulation of pulmonary inflammation and fibrosis by CCL18. Am J Pathol (2007) 1.28
Susceptibility to liver fibrosis in mice expressing a connective tissue growth factor transgene in hepatocytes. Hepatology (2009) 1.28
Novel therapeutic approaches for pulmonary fibrosis. Br J Pharmacol (2011) 1.24
Adenosine metabolism and murine strain-specific IL-4-induced inflammation, emphysema, and fibrosis. J Clin Invest (2006) 1.22
The role of mouse strain differences in the susceptibility to fibrosis: a systematic review. Fibrogenesis Tissue Repair (2013) 1.13
Conditional overexpression of connective tissue growth factor disrupts postnatal lung development. Am J Respir Cell Mol Biol (2009) 1.11
Fibrosis of two: Epithelial cell-fibroblast interactions in pulmonary fibrosis. Biochim Biophys Acta (2013) 1.11
Roles for CCN2 in normal physiological processes. Cell Mol Life Sci (2011) 1.06
Thrombospondin-1-deficient mice are not protected from bleomycin-induced pulmonary fibrosis. Am J Respir Cell Mol Biol (2010) 1.06
Connective tissue growth factor causes EMT-like cell fate changes in vivo and in vitro. J Cell Sci (2013) 1.03
The immunology of fibrosis: innate and adaptive responses. Trends Immunol (2010) 1.01
Blocking follistatin-like 1 attenuates bleomycin-induced pulmonary fibrosis in mice. J Exp Med (2015) 0.98
Adenoviral gene transfer of bioactive TGFbeta1 to the rodent eye as a novel model for anterior subcapsular cataract. Mol Vis (2007) 0.93
Hypoxia in human trophoblasts stimulates the expression and secretion of connective tissue growth factor. Endocrinology (2008) 0.93
TGF-beta, IL-6, IL-17 and CTGF direct multiple pathologies of chronic cardiac allograft rejection. Immunotherapy (2010) 0.92
Towards an anti-fibrotic therapy for scleroderma: targeting myofibroblast differentiation and recruitment. Fibrogenesis Tissue Repair (2010) 0.90
Matrilysin (Matrix Metalloproteinase-7) regulates anti-inflammatory and antifibrotic pulmonary dendritic cells that express CD103 (alpha(E)beta(7)-integrin). Am J Pathol (2009) 0.90
Activin, neutrophils, and inflammation: just coincidence? Semin Immunopathol (2013) 0.85
alpha2-antiplasmin is associated with the progression of fibrosis. Am J Pathol (2009) 0.84
Matrix, mesenchyme, and mechanotransduction. Ann Am Thorac Soc (2015) 0.84
Silencing of WISP3 suppresses gastric cancer cell proliferation and metastasis and inhibits Wnt/β-catenin signaling. Int J Clin Exp Pathol (2014) 0.83
Connective tissue growth factor (CTGF) expression modulates response to high glucose. PLoS One (2013) 0.81
Differential Immunometabolic Phenotype in Th1 and Th2 Dominant Mouse Strains in Response to High-Fat Feeding. PLoS One (2015) 0.78
Getting out of a sticky situation: targeting the myofibroblast in scleroderma. Open Rheumatol J (2012) 0.77
Expression variations of connective tissue growth factor in pulmonary arteries from smokers with and without chronic obstructive pulmonary disease. Sci Rep (2015) 0.77
Tracheal Aspirate Levels of the Matricellular Protein SPARC Predict Development of Bronchopulmonary Dysplasia. PLoS One (2015) 0.76
TAZ contributes to pulmonary fibrosis by activating profibrotic functions of lung fibroblasts. Sci Rep (2017) 0.76
Comparison of bleomycin-induced pulmonary apoptosis between NMRI mice and C57BL/6 mice. Res Pharm Sci (2013) 0.75
Efficacy and safety of nintedanib in idiopathic pulmonary fibrosis. N Engl J Med (2014) 10.62
Beta-catenin and TCF mediate cell positioning in the intestinal epithelium by controlling the expression of EphB/ephrinB. Cell (2002) 8.08
Circulating fibrocytes are an indicator of poor prognosis in idiopathic pulmonary fibrosis. Am J Respir Crit Care Med (2009) 4.41
The bleomycin animal model: a useful tool to investigate treatment options for idiopathic pulmonary fibrosis? Int J Biochem Cell Biol (2007) 3.33
Smad3 null mice develop airspace enlargement and are resistant to TGF-beta-mediated pulmonary fibrosis. J Immunol (2004) 2.95
Ly6Chi monocytes direct alternatively activated profibrotic macrophage regulation of lung fibrosis. Am J Respir Crit Care Med (2011) 2.15
Regulation of transforming growth factor-β1-driven lung fibrosis by galectin-3. Am J Respir Crit Care Med (2011) 2.09
Pro: Inflammatory mechanisms are a minor component of the pathogenesis of idiopathic pulmonary fibrosis. Am J Respir Crit Care Med (2002) 2.08
Pulmonary fibrosis: searching for model answers. Am J Respir Cell Mol Biol (2005) 2.05
Adenoviral gene transfer of connective tissue growth factor in the lung induces transient fibrosis. Am J Respir Crit Care Med (2003) 2.05
Metastatic growth from dormant cells induced by a col-I-enriched fibrotic environment. Cancer Res (2010) 1.95
TGF-beta and Smad3 signaling link inflammation to chronic fibrogenesis. J Immunol (2005) 1.85
Effects of budesonide and formoterol on allergen-induced airway responses, inflammation, and airway remodeling in asthma. J Allergy Clin Immunol (2009) 1.76
Significant mobilization of both conventional and regulatory T cells with AMD3100. Blood (2011) 1.73
Progressive transforming growth factor beta1-induced lung fibrosis is blocked by an orally active ALK5 kinase inhibitor. Am J Respir Crit Care Med (2004) 1.66
Meta-analysis: peritoneal membrane transport, mortality, and technique failure in peritoneal dialysis. J Am Soc Nephrol (2006) 1.65
Differences in the fibrogenic response after transfer of active transforming growth factor-beta1 gene to lungs of "fibrosis-prone" and "fibrosis-resistant" mouse strains. Am J Respir Cell Mol Biol (2002) 1.61
Prolonged peritoneal gene expression using a helper-dependent adenovirus. Perit Dial Int (2009) 1.55
Re-evaluation of fibrogenic cytokines in lung fibrosis. Curr Pharm Des (2003) 1.52
Dysfunction and remodeling of the mouse airway persist after resolution of acute allergen-induced airway inflammation. Am J Respir Cell Mol Biol (2002) 1.49
The pathophysiology of the peritoneal membrane. J Am Soc Nephrol (2010) 1.47
Vascular endothelial growth factor expression in peritoneal mesothelial cells undergoing transdifferentiation. Perit Dial Int (2008) 1.47
A new direction in the pathogenesis of idiopathic pulmonary fibrosis? Respir Res (2001) 1.47
Transforming growth factor-β: activation by neuraminidase and role in highly pathogenic H5N1 influenza pathogenesis. PLoS Pathog (2010) 1.44
Suppression of tumorigenicity by adenovirus-mediated gene transfer of decorin. Oncogene (2002) 1.42
VEGF ameliorates pulmonary hypertension through inhibition of endothelial apoptosis in experimental lung fibrosis in rats. J Clin Invest (2009) 1.41
Transforming growth factor-beta regulates house dust mite-induced allergic airway inflammation but not airway remodeling. Am J Respir Crit Care Med (2008) 1.40
Myofibroblast differentiation is induced in keratinocyte-fibroblast co-cultures and is antagonistically regulated by endogenous transforming growth factor-beta and interleukin-1. Am J Pathol (2004) 1.39
Three spectrophotometric assays for the measurement of the five respiratory chain complexes in minuscule biological samples. Clin Chim Acta (2006) 1.38
TGF-beta1 induces progressive pleural scarring and subpleural fibrosis. J Immunol (2007) 1.36
Low-intensity warfarin is ineffective for the prevention of PTFE graft failure in patients on hemodialysis: a randomized controlled trial. J Am Soc Nephrol (2002) 1.34
Antigen presentation by exosomes released from peptide-pulsed dendritic cells is not suppressed by the presence of active CTL. J Immunol (2007) 1.32
Pulmonary hypertension and idiopathic pulmonary fibrosis: a tale of angiogenesis, apoptosis, and growth factors. Am J Respir Cell Mol Biol (2010) 1.28
Costimulatory ligand 4-1BBL (CD137L) as an efficient adjuvant for human antiviral cytotoxic T cell responses. Proc Natl Acad Sci U S A (2004) 1.27
Matrix metalloproteinase 3 is a mediator of pulmonary fibrosis. Am J Pathol (2011) 1.27
Mouse and human lung fibroblasts regulate dendritic cell trafficking, airway inflammation, and fibrosis through integrin αvβ8-mediated activation of TGF-β. J Clin Invest (2011) 1.25
A human type 5 adenovirus-based tuberculosis vaccine induces robust T cell responses in humans despite preexisting anti-adenovirus immunity. Sci Transl Med (2013) 1.22
Overexpression of tumor necrosis factor-alpha diminishes pulmonary fibrosis induced by bleomycin or transforming growth factor-beta. Am J Respir Cell Mol Biol (2003) 1.20
Comparative evaluation of two severe acute respiratory syndrome (SARS) vaccine candidates in mice challenged with SARS coronavirus. J Gen Virol (2006) 1.16
Negative regulation of lung inflammation and immunopathology by TNF-α during acute influenza infection. Am J Pathol (2011) 1.16
Transforming growth factor-beta 1-mediated neuroprotection against excitotoxic injury in vivo. J Cereb Blood Flow Metab (2003) 1.16
TGF-beta1 gene transfer to the mouse colon leads to intestinal fibrosis. Am J Physiol Gastrointest Liver Physiol (2005) 1.15
Smad3-dependent and -independent pathways are involved in peritoneal membrane injury. Kidney Int (2009) 1.15
Lung development and susceptibility to chronic obstructive pulmonary disease. Proc Am Thorac Soc (2006) 1.15
Epithelial expression of profibrotic mediators in a model of allergen-induced airway remodeling. Am J Respir Cell Mol Biol (2004) 1.14
The role of mouse strain differences in the susceptibility to fibrosis: a systematic review. Fibrogenesis Tissue Repair (2013) 1.13
Progressive pulmonary fibrosis is mediated by TGF-beta isoform 1 but not TGF-beta3. Int J Biochem Cell Biol (2007) 1.11
Gene transfer of matrix metalloproteinase-9 induces tumor regression of breast cancer in vivo. Cancer Res (2008) 1.11
Ocular gene transfer of active TGF-beta induces changes in anterior segment morphology and elevated IOP in rats. Invest Ophthalmol Vis Sci (2009) 1.10
TNF-alpha reduces cerebral blood volume and disrupts tissue homeostasis via an endothelin- and TNFR2-dependent pathway. Brain (2002) 1.09
Smad3 signaling involved in pulmonary fibrosis and emphysema. Proc Am Thorac Soc (2006) 1.09
Severe acute respiratory syndrome vaccine efficacy in ferrets: whole killed virus and adenovirus-vectored vaccines. J Gen Virol (2008) 1.07
Targeting genes for treatment in idiopathic pulmonary fibrosis: challenges and opportunities, promises and pitfalls. Proc Am Thorac Soc (2006) 1.07
Anxiety and cognition in histamine H3 receptor-/- mice. Eur J Neurosci (2004) 1.07
Inhibition of HSP27 blocks fibrosis development and EMT features by promoting Snail degradation. FASEB J (2013) 1.06
ParticipACTION: A mass media campaign targeting parents of inactive children; knowledge, saliency, and trialing behaviours. Int J Behav Nutr Phys Act (2009) 1.05
Estradiol increases extracellular levels of vascular endothelial growth factor in vivo in murine mammary cancer. Int J Cancer (2003) 1.04
Inflammatory cytokines, angiogenesis, and fibrosis in the rat peritoneum. Am J Pathol (2002) 1.04
Lens-specific expression of TGF-beta induces anterior subcapsular cataract formation in the absence of Smad3. Invest Ophthalmol Vis Sci (2006) 1.03
Fatal pericardial tamponade after Wallstent implantation for malignant superior vena cava syndrome. J Endovasc Ther (2002) 1.02
Idiopathic pulmonary fibrosis: from epithelial injury to biomarkers--insights from the bench side. Respiration (2013) 1.00
Comparison between conventional and "clinical" assessment of experimental lung fibrosis. J Transl Med (2008) 1.00
Therapeutic effect of angiostatin gene transfer in a murine model of endometriosis. Am J Pathol (2002) 1.00
Angiogenesis in pulmonary fibrosis: too much or not enough? Chest (2012) 1.00
Severe sepsis exacerbates cell-mediated immunity in the lung due to an altered dendritic cell cytokine profile. Am J Pathol (2006) 0.99
Transforming growth factor-beta: importance in long-term peritoneal membrane changes. Perit Dial Int (2005) 0.99