Published in Am J Respir Cell Mol Biol on November 24, 2004
Allergen-induced peribronchial fibrosis and mucus production mediated by IkappaB kinase beta-dependent genes in airway epithelium. Proc Natl Acad Sci U S A (2005) 1.87
Adiponectin deficiency increases allergic airway inflammation and pulmonary vascular remodeling. Am J Respir Cell Mol Biol (2009) 1.65
Transforming growth factor-beta1 suppresses airway hyperresponsiveness in allergic airway disease. Am J Respir Crit Care Med (2007) 1.63
Jun N-terminal kinase 1 regulates epithelial-to-mesenchymal transition induced by TGF-beta1. J Cell Sci (2008) 1.60
c-Jun N-terminal kinase 1 is required for the development of pulmonary fibrosis. Am J Respir Cell Mol Biol (2008) 1.26
Airway epithelial cells from asthmatic children differentially express proremodeling factors. J Allergy Clin Immunol (2012) 1.13
Extracellular matrix remodeling by dynamic strain in a three-dimensional tissue-engineered human airway wall model. Am J Respir Cell Mol Biol (2006) 1.09
Time course of airway remodelling after an acute chlorine gas exposure in mice. Respir Res (2008) 1.08
Induction of the plasminogen activator system by mechanical stimulation of human bronchial epithelial cells. Am J Respir Cell Mol Biol (2006) 1.04
Allergen-induced airway remodelling. Eur Respir J (2007) 0.98
Controversy surrounding the increased expression of TGF beta 1 in asthma. Respir Res (2007) 0.92
Augmentation of arginase 1 expression by exposure to air pollution exacerbates the airways hyperresponsiveness in murine models of asthma. Respir Res (2011) 0.89
Coagulation factor Xa modulates airway remodeling in a murine model of asthma. Am J Respir Crit Care Med (2006) 0.88
The -675 4G/5G polymorphism in plasminogen activator inhibitor-1 gene is associated with risk of asthma: a meta-analysis. PLoS One (2012) 0.87
A severe deficiency of coagulation factor VIIa results in attenuation of the asthmatic response in mice. Am J Physiol Lung Cell Mol Physiol (2009) 0.85
Laser capture microdissection reveals dose-response of gene expression in situ consequent to asbestos exposure. Int J Exp Pathol (2007) 0.82
Cross-talk between human mast cells and bronchial epithelial cells in plasminogen activator inhibitor-1 production via transforming growth factor-β1. Am J Respir Cell Mol Biol (2015) 0.79
Asthmatic airway epithelial cells differentially regulate fibroblast expression of extracellular matrix components. J Allergy Clin Immunol (2014) 0.79
Immune Modulation of the T Cell Response in Asthma through Wnt10b. Am J Respir Cell Mol Biol (2016) 0.75
Plasminogen activator inhibitor-1 does not contribute to the pulmonary pathology induced by acute exposure to ozone. Physiol Rep (2016) 0.75
Interplay of extracellular matrix and leukocytes in lung inflammation. Cell Immunol (2016) 0.75
Mepolizumab for prednisone-dependent asthma with sputum eosinophilia. N Engl J Med (2009) 5.90
Circulating fibrocytes are an indicator of poor prognosis in idiopathic pulmonary fibrosis. Am J Respir Crit Care Med (2009) 4.41
Improving quality of care for acute myocardial infarction: The Guidelines Applied in Practice (GAP) Initiative. JAMA (2002) 4.36
The bleomycin animal model: a useful tool to investigate treatment options for idiopathic pulmonary fibrosis? Int J Biochem Cell Biol (2007) 3.33
Smad3 null mice develop airspace enlargement and are resistant to TGF-beta-mediated pulmonary fibrosis. J Immunol (2004) 2.95
Effects of an anti-TSLP antibody on allergen-induced asthmatic responses. N Engl J Med (2014) 2.53
Continuous exposure to house dust mite elicits chronic airway inflammation and structural remodeling. Am J Respir Crit Care Med (2003) 2.44
A GABAergic system in airway epithelium is essential for mucus overproduction in asthma. Nat Med (2007) 2.43
Lactobacillus reuteri-induced regulatory T cells protect against an allergic airway response in mice. Am J Respir Crit Care Med (2008) 2.39
Ly6Chi monocytes direct alternatively activated profibrotic macrophage regulation of lung fibrosis. Am J Respir Crit Care Med (2011) 2.15
Regulation of transforming growth factor-β1-driven lung fibrosis by galectin-3. Am J Respir Crit Care Med (2011) 2.09
Pro: Inflammatory mechanisms are a minor component of the pathogenesis of idiopathic pulmonary fibrosis. Am J Respir Crit Care Med (2002) 2.08
Intranasal exposure of mice to house dust mite elicits allergic airway inflammation via a GM-CSF-mediated mechanism. J Immunol (2004) 2.06
Pulmonary fibrosis: searching for model answers. Am J Respir Cell Mol Biol (2005) 2.05
Adenoviral gene transfer of connective tissue growth factor in the lung induces transient fibrosis. Am J Respir Crit Care Med (2003) 2.05
Canadian Thoracic Society 2012 guideline update: diagnosis and management of asthma in preschoolers, children and adults. Can Respir J (2012) 1.96
Interstitial lung disease induced by drugs and radiation. Respiration (2004) 1.95
Metastatic growth from dormant cells induced by a col-I-enriched fibrotic environment. Cancer Res (2010) 1.95
Eosinophilic bronchitis in asthma: a model for establishing dose-response and relative potency of inhaled corticosteroids. J Allergy Clin Immunol (2006) 1.93
TGF-beta and Smad3 signaling link inflammation to chronic fibrogenesis. J Immunol (2005) 1.85
Transient overexpression of TGF-{beta}1 induces epithelial mesenchymal transition in the rodent peritoneum. J Am Soc Nephrol (2004) 1.81
Effects of budesonide and formoterol on allergen-induced airway responses, inflammation, and airway remodeling in asthma. J Allergy Clin Immunol (2009) 1.76
Oral treatment with live Lactobacillus reuteri inhibits the allergic airway response in mice. Am J Respir Crit Care Med (2007) 1.75
Progressive transforming growth factor beta1-induced lung fibrosis is blocked by an orally active ALK5 kinase inhibitor. Am J Respir Crit Care Med (2004) 1.66
Differences in the fibrogenic response after transfer of active transforming growth factor-beta1 gene to lungs of "fibrosis-prone" and "fibrosis-resistant" mouse strains. Am J Respir Cell Mol Biol (2002) 1.61
Influence of zafirlukast and loratadine on exercise-induced bronchoconstriction. J Allergy Clin Immunol (2002) 1.56
Epithelial cells and airway diseases. Immunol Rev (2011) 1.56
Ischemia in broca area is associated with broca aphasia more reliably in acute than in chronic stroke. Stroke (2009) 1.56
Transfer of the active form of transforming growth factor-beta 1 gene to newborn rat lung induces changes consistent with bronchopulmonary dysplasia. Am J Pathol (2003) 1.53
Re-evaluation of fibrogenic cytokines in lung fibrosis. Curr Pharm Des (2003) 1.52
Dysfunction and remodeling of the mouse airway persist after resolution of acute allergen-induced airway inflammation. Am J Respir Cell Mol Biol (2002) 1.49
Safety of sputum induction in moderate-to-severe smoking-related chronic obstructive pulmonary disease. COPD (2006) 1.47
Acute Stroke Imaging Research Roadmap II. Stroke (2013) 1.47
Transforming growth factor-β: activation by neuraminidase and role in highly pathogenic H5N1 influenza pathogenesis. PLoS Pathog (2010) 1.44
Effect of the management of patients with chronic cough by pulmonologists and certified respiratory educators on quality of life: a randomized trial. Chest (2009) 1.43
Increased levels of airway neutrophils reduce the inhibitory effects of inhaled glucocorticosteroids on allergen-induced airway eosinophils. Can Respir J (2002) 1.43
Effects of benralizumab on airway eosinophils in asthmatic patients with sputum eosinophilia. J Allergy Clin Immunol (2013) 1.42
Suppression of tumorigenicity by adenovirus-mediated gene transfer of decorin. Oncogene (2002) 1.42
VEGF ameliorates pulmonary hypertension through inhibition of endothelial apoptosis in experimental lung fibrosis in rats. J Clin Invest (2009) 1.41
A practical guide to the monitoring and management of the complications of systemic corticosteroid therapy. Allergy Asthma Clin Immunol (2013) 1.40
Clinical models to compare the safety and efficacy of inhaled corticosteroids in patients with asthma. Can Respir J (2003) 1.40
Transforming growth factor-beta regulates house dust mite-induced allergic airway inflammation but not airway remodeling. Am J Respir Crit Care Med (2008) 1.40
Myofibroblast differentiation is induced in keratinocyte-fibroblast co-cultures and is antagonistically regulated by endogenous transforming growth factor-beta and interleukin-1. Am J Pathol (2004) 1.39
Three spectrophotometric assays for the measurement of the five respiratory chain complexes in minuscule biological samples. Clin Chim Acta (2006) 1.38
Effects of cardiorespiratory fitness and cerebral blood flow on cognitive outcomes in older women. Neurobiol Aging (2008) 1.37
TGF-beta1 induces progressive pleural scarring and subpleural fibrosis. J Immunol (2007) 1.36
Intracranial plaque enhancement in patients with cerebrovascular events on high-spatial-resolution MR images. Radiology (2014) 1.35
Antigen presentation by exosomes released from peptide-pulsed dendritic cells is not suppressed by the presence of active CTL. J Immunol (2007) 1.32
Connective tissue growth factor is crucial to inducing a profibrotic environment in "fibrosis-resistant" BALB/c mouse lungs. Am J Respir Cell Mol Biol (2004) 1.31
Drug-induced and iatrogenic infiltrative lung disease. Clin Chest Med (2004) 1.28
Pulmonary hypertension and idiopathic pulmonary fibrosis: a tale of angiogenesis, apoptosis, and growth factors. Am J Respir Cell Mol Biol (2010) 1.28
Costimulatory ligand 4-1BBL (CD137L) as an efficient adjuvant for human antiviral cytotoxic T cell responses. Proc Natl Acad Sci U S A (2004) 1.27
House dust mite facilitates ovalbumin-specific allergic sensitization and airway inflammation. Am J Respir Crit Care Med (2005) 1.27
Matrix metalloproteinase 3 is a mediator of pulmonary fibrosis. Am J Pathol (2011) 1.27
Mouse and human lung fibroblasts regulate dendritic cell trafficking, airway inflammation, and fibrosis through integrin αvβ8-mediated activation of TGF-β. J Clin Invest (2011) 1.25
Type 2 cytokines in the pathogenesis of sustained airway dysfunction and airway remodeling in mice. Am J Respir Crit Care Med (2003) 1.25
Effect of interferon-gamma on allergic airway responses in interferon-gamma-deficient mice. Am J Respir Crit Care Med (2002) 1.24
Kinetics of bone marrow eosinophilopoiesis and associated cytokines after allergen inhalation. Am J Respir Crit Care Med (2003) 1.24
A human type 5 adenovirus-based tuberculosis vaccine induces robust T cell responses in humans despite preexisting anti-adenovirus immunity. Sci Transl Med (2013) 1.22
Basic mechanisms and clinical implications of peritoneal fibrosis. Perit Dial Int (2004) 1.21
Overexpression of tumor necrosis factor-alpha diminishes pulmonary fibrosis induced by bleomycin or transforming growth factor-beta. Am J Respir Cell Mol Biol (2003) 1.20
Heat shock proteins: cell protection through protein triage. ScientificWorldJournal (2010) 1.19
Influence of airway wall stiffness and parenchymal tethering on the dynamics of bronchoconstriction. Am J Physiol Lung Cell Mol Physiol (2010) 1.16
Airway hyperresponsiveness. Chest (2003) 1.16
Comparative evaluation of two severe acute respiratory syndrome (SARS) vaccine candidates in mice challenged with SARS coronavirus. J Gen Virol (2006) 1.16
Negative regulation of lung inflammation and immunopathology by TNF-α during acute influenza infection. Am J Pathol (2011) 1.16
Transforming growth factor-beta 1-mediated neuroprotection against excitotoxic injury in vivo. J Cereb Blood Flow Metab (2003) 1.16
A new short-term mouse model of chronic obstructive pulmonary disease identifies a role for mast cell tryptase in pathogenesis. J Allergy Clin Immunol (2013) 1.16
Lung development and susceptibility to chronic obstructive pulmonary disease. Proc Am Thorac Soc (2006) 1.15
TGF-beta1 gene transfer to the mouse colon leads to intestinal fibrosis. Am J Physiol Gastrointest Liver Physiol (2005) 1.15
Repression of inflammatory gene expression in human pulmonary epithelial cells by small-molecule IkappaB kinase inhibitors. J Pharmacol Exp Ther (2007) 1.11
Gene transfer of matrix metalloproteinase-9 induces tumor regression of breast cancer in vivo. Cancer Res (2008) 1.11
Progressive pulmonary fibrosis is mediated by TGF-beta isoform 1 but not TGF-beta3. Int J Biochem Cell Biol (2007) 1.11
Ocular gene transfer of active TGF-beta induces changes in anterior segment morphology and elevated IOP in rats. Invest Ophthalmol Vis Sci (2009) 1.10
TNF-alpha reduces cerebral blood volume and disrupts tissue homeostasis via an endothelin- and TNFR2-dependent pathway. Brain (2002) 1.09
Smad3 signaling involved in pulmonary fibrosis and emphysema. Proc Am Thorac Soc (2006) 1.09
Targeting genes for treatment in idiopathic pulmonary fibrosis: challenges and opportunities, promises and pitfalls. Proc Am Thorac Soc (2006) 1.07
Is interleukin-13 critical in maintaining airway hyperresponsiveness in allergen-challenged mice? Am J Respir Crit Care Med (2004) 1.07
Severe acute respiratory syndrome vaccine efficacy in ferrets: whole killed virus and adenovirus-vectored vaccines. J Gen Virol (2008) 1.07
Inhibition of HSP27 blocks fibrosis development and EMT features by promoting Snail degradation. FASEB J (2013) 1.06
Pathogenesis of murine experimental allergic rhinitis: a study of local and systemic consequences of IL-5 deficiency. J Immunol (2002) 1.06