Published in Endocrinology on July 15, 2004
Novel ghrelin assays provide evidence for independent regulation of ghrelin acylation and secretion in healthy young men. J Clin Endocrinol Metab (2008) 1.96
The pharmacokinetics of acyl, des-acyl, and total ghrelin in healthy human subjects. Eur J Endocrinol (2013) 1.36
Ghrelin. Mol Metab (2015) 1.29
Physiologic concentrations of exogenously infused ghrelin reduces insulin secretion without affecting insulin sensitivity in healthy humans. J Clin Endocrinol Metab (2013) 1.08
Structure and physiological actions of ghrelin. Scientifica (Cairo) (2013) 1.06
Kinetics of human serum butyrylcholinesterase inhibition by a novel experimental Alzheimer therapeutic, dihydrobenzodioxepine cymserine. Neurochem Res (2007) 1.04
Plasma butyrylcholinesterase regulates ghrelin to control aggression. Proc Natl Acad Sci U S A (2015) 0.99
Comparison of competitive radioimmunoassays and two-site sandwich assays for the measurement and interpretation of plasma ghrelin levels. J Clin Endocrinol Metab (2010) 0.98
Ghrelin-induced activation of cAMP signal transduction and its negative regulation by endocannabinoids in the hippocampus. Neuropharmacology (2010) 0.96
Stress-related alterations of acyl and desacyl ghrelin circulating levels: mechanisms and functional implications. Peptides (2011) 0.90
Catalytic antibody degradation of ghrelin increases whole-body metabolic rate and reduces refeeding in fasting mice. Proc Natl Acad Sci U S A (2008) 0.90
Acylated ghrelin concentrations are markedly decreased during pregnancy in mothers with and without gestational diabetes: relationship with cholinesterase. Am J Physiol Endocrinol Metab (2009) 0.88
Acylation type determines ghrelin's effects on energy homeostasis in rodents. Endocrinology (2012) 0.88
Abdominal surgery inhibits circulating acyl ghrelin and ghrelin-O-acyltransferase levels in rats: role of the somatostatin receptor subtype 2. Am J Physiol Gastrointest Liver Physiol (2011) 0.87
Regulation of ghrelin structure and membrane binding by phosphorylation. Peptides (2008) 0.85
Elevated ratio of acylated to unacylated ghrelin in children and young adults with Prader-Willi syndrome. Endocrine (2015) 0.84
Administration of exogenous acylated ghrelin or rikkunshito, an endogenous ghrelin enhancer, improves the decrease in postprandial gastric motility in an acute restraint stress mouse model. Neurogastroenterol Motil (2014) 0.84
Molecular forms of butyrylcholinesterase and obesity. Genet Mol Biol (2010) 0.83
The intestinal lymph fistula model--a novel approach to study ghrelin secretion. Am J Physiol Gastrointest Liver Physiol (2009) 0.82
Comparison of 5 monoclonal antibodies for immunopurification of human butyrylcholinesterase on Dynabeads: KD values, binding pairs, and amino acid sequences. Chem Biol Interact (2015) 0.81
Immunohistochemical localization of ghrelin in rodent kidneys. Histochem Cell Biol (2006) 0.80
Cholinesterase and paraoxonase (PON1) enzyme activities in Mexican-American mothers and children from an agricultural community. J Expo Sci Environ Epidemiol (2012) 0.80
Radiometric assay of ghrelin hydrolase activity and (3)H-ghrelin distribution into mouse tissues. Biochem Pharmacol (2015) 0.79
Comparison of cognitive functions between people with silent and wild-type butyrylcholinesterase. J Neural Transm (Vienna) (2007) 0.79
Brain circuits mediating the orexigenic action of peripheral ghrelin: narrow gates for a vast kingdom. Front Endocrinol (Lausanne) (2015) 0.78
The effects of graded levels of calorie restriction: VI. Impact of short-term graded calorie restriction on transcriptomic responses of the hypothalamic hunger and circadian signaling pathways. Aging (Albany NY) (2016) 0.77
Effects of glucose and insulin on acyl ghrelin and desacyl ghrelin, leptin, and adiponectin in pregnant women with diabetes. Metabolism (2009) 0.77
A New Strategy Using Rikkunshito to Treat Anorexia and Gastrointestinal Dysfunction. Evid Based Complement Alternat Med (2015) 0.77
Potential anti-obesity effects of a long-acting cocaine hydrolase. Chem Biol Interact (2016) 0.76
Multi-species sequence comparison reveals conservation of ghrelin gene-derived splice variants encoding a truncated ghrelin peptide. Endocrine (2016) 0.76
Physiological roles for butyrylcholinesterase: A BChE-ghrelin axis. Chem Biol Interact (2016) 0.76
The Pentapeptide RM-131 Promotes Food Intake and Adiposity in Wildtype Mice but Not in Mice Lacking the Ghrelin Receptor. Front Nutr (2015) 0.76
Appetite regulation is independent of the changes in ghrelin levels in pregnant rats fed low-protein diet. Physiol Rep (2015) 0.76
Changes in plasma ghrelin and leptin levels in patients with peptic ulcer and gastritis following eradication of Helicobacter pylori infection. BMC Gastroenterol (2016) 0.75
Cysteine thioesters as myelin proteolipid protein analogues to examine the role of butyrylcholinesterase in myelin decompaction. ACS Chem Neurosci (2010) 0.75
Recent advances in potential clinical application of ghrelin in obesity. J Obes (2012) 0.75
Is Ghrelin Synthesized in the Central Nervous System? Int J Mol Sci (2017) 0.75
Therapeutic Potential of Targeting the Ghrelin Pathway. Int J Mol Sci (2017) 0.75
Ghrelin-Reactive Immunoglobulins in Conditions of Altered Appetite and Energy Balance. Front Endocrinol (Lausanne) (2017) 0.75
Butyrylcholinesterase Deficiency Promotes Adipose Tissue Growth and Hepatic Lipid Accumulation in Male Mice on High-Fat Diet. Endocrinology (2016) 0.75
Unexpected Reaction Pathway for butyrylcholinesterase-catalyzed inactivation of "hunger hormone" ghrelin. Sci Rep (2016) 0.75
Identification of α2 macroglobulin as a major serum ghrelin esterase. Angew Chem Int Ed Engl (2011) 0.75
New Insights into Butyrylcholinesterase Activity Assay: Serum Dilution Factor as a Crucial Parameter. PLoS One (2015) 0.75
Obesity and variants of the GHRL (ghrelin) and BCHE (butyrylcholinesterase) genes. Genet Mol Biol (2011) 0.75
Research priorities in cancer cachexia: The University of Rochester Cancer Center NCI Community Oncology Research Program Research Base Symposium on Cancer Cachexia and Sarcopenia. Curr Opin Support Palliat Care (2017) 0.75
The Role of Ghrelin and Ghrelin Signaling in Aging. Int J Mol Sci (2017) 0.75
The ghrelin/GOAT system regulates obesity-induced inflammation in male mice. Endocrinology (2017) 0.75
Growth hormone secretagogues hexarelin and JMV2894 protect skeletal muscle from mitochondrial damages in a rat model of cisplatin-induced cachexia. Sci Rep (2017) 0.75
The C-terminal nonapeptide of mature chemerin activates the chemerin receptor with low nanomolar potency. J Biol Chem (2003) 1.67
Techniques: promiscuous Galpha proteins in basic research and drug discovery. Trends Pharmacol Sci (2005) 1.21
Identification and characterization of an endogenous chemotactic ligand specific for FPRL2. J Exp Med (2004) 1.14
Murine 3T3-L1 adipocyte cell differentiation model: validated reference genes for qPCR gene expression analysis. PLoS One (2012) 1.06
Transfer of the AQP1 cDNA for the correction of radiation-induced salivary hypofunction. Biochim Biophys Acta (2005) 0.99
Contribution of the carboxyl terminus of the VPAC1 receptor to agonist-induced receptor phosphorylation, internalization, and recycling. J Biol Chem (2005) 0.95
Antisecretory actions of a novel vasoactive intestinal polypeptide (VIP) antagonist in human and rat small intestine. Br J Pharmacol (2005) 0.93
Interaction of the growth hormone-releasing peptides ghrelin and growth hormone-releasing peptide-6 with the motilin receptor in the rabbit gastric antrum. J Pharmacol Exp Ther (2003) 0.93
G protein activation by G protein coupled receptors: ternary complex formation or catalyzed reaction? Biochem Pharmacol (2004) 0.92
Spatial proximity between the VPAC1 receptor and the amino terminus of agonist and antagonist peptides reveals distinct sites of interaction. FASEB J (2012) 0.91
Ghrelin interacts with human plasma lipoproteins. Endocrinology (2007) 0.91
Desensitization of the human motilin receptor by motilides. J Pharmacol Exp Ther (2005) 0.91
Modified aquaporin 5 expression and distribution in submandibular glands from NOD mice displaying autoimmune exocrinopathy. Arthritis Rheum (2007) 0.90
Focus on the short- and long-term effects of ghrelin on energy homeostasis. Nutrition (2010) 0.90
Analysis of the glucagon receptor first extracellular loop by the substituted cysteine accessibility method. Peptides (2011) 0.90
Pharmacological properties of Chinese hamster ovary cells coexpressing two vasoactive intestinal peptide receptors (hVPAC1 and hVPAC2). Br J Pharmacol (2006) 0.87
Mutational and cysteine scanning analysis of the glucagon receptor N-terminal domain. J Biol Chem (2010) 0.87
Glomerular and proximal tubule cysts as early manifestations of Pkd1 deletion. Nephrol Dial Transplant (2009) 0.85
Propiverine and metabolites: differences in binding to muscarinic receptors and in functional models of detrusor contraction. Naunyn Schmiedebergs Arch Pharmacol (2006) 0.85
Ghrelin: a new peptide regulating growth hormone release and food intake. Int J Biochem Cell Biol (2007) 0.84
Comparative efficacy of VIP and analogs on activation and internalization of the recombinant VPAC2 receptor expressed in CHO cells. Peptides (2004) 0.84
Influence of ghrelin on food intake and energy homeostasis. Curr Opin Clin Nutr Metab Care (2007) 0.83
Ghrelin is produced by the human erythroleukemic HEL cell line and involved in an autocrine pathway leading to cell proliferation. Endocrinology (2004) 0.83
Mutations in the carboxy-terminus of the third intracellular loop of the human recombinant VPAC1 receptor impair VIP-stimulated [Ca2+]i increase but not adenylate cyclase stimulation. Cell Signal (2005) 0.83
Ala-scan of ghrelin (1-14): interaction with the recombinant human ghrelin receptor. Peptides (2004) 0.82
Effect of inactivating mutations on phosphorylation and internalization of the human VPAC2 receptor. J Mol Endocrinol (2005) 0.82
Evidence for a direct and functional interaction between the regulators of G protein signaling-2 and phosphorylated C terminus of cholecystokinin-2 receptor. Mol Pharmacol (2008) 0.82
Distribution of salivary aquaporin-5 in Sjögren's syndrome. Lancet (2002) 0.82
Aquaporin expression and function in human pluripotent stem cell-derived retinal pigmented epithelial cells. Invest Ophthalmol Vis Sci (2013) 0.81
Inhibitory pathways in the circular muscle of rat jejunum. Br J Pharmacol (2004) 0.81
Aquaporin expression in blood-retinal barrier cells during experimental autoimmune uveitis. Mol Vis (2010) 0.81
VIP blockade leads to microcephaly in mice via disruption of Mcph1-Chk1 signaling. J Clin Invest (2011) 0.81
Aquaporin-4 overexpression in rat ALS model. Anat Rec (Hoboken) (2009) 0.81
Autocrine proliferative effect of ghrelin on leukemic HL-60 and THP-1 cells. J Endocrinol (2007) 0.80
Perturbation of glycerol metabolism in hepatocytes from n3-PUFA-depleted rats. Int J Mol Med (2012) 0.80
Treatment with infliximab restores normal aquaporin 5 distribution in minor salivary glands of patients with Sjögren's syndrome. Arthritis Rheum (2002) 0.80
Asn229 in the third helix of VPAC1 receptor is essential for receptor activation but not for receptor phosphorylation and internalization: comparison with Asn216 in VPAC2 receptor. Cell Signal (2006) 0.79
Parotid Gland Biopsy as an Additional Diagnostic Tool for Supporting the Diagnosis of Sjögren's Syndrome. Int J Rheumatol (2011) 0.78
Cell surface targeting of VPAC1 receptors: evidence for implication of a quality control system and the proteasome. Biochim Biophys Acta (2008) 0.78
Hexanoylation of a VPAC2 receptor-preferring ligand markedly increased its selectivity and potency. Peptides (2004) 0.78
Expression of the electrogenic Na+-HCO3--cotransporter NBCe1 in tumoral insulin-producing BRIN-BD11 cells. Cell Physiol Biochem (2009) 0.78
Pancreatic beta-cells: Role of glycerol and aquaglyceroporin 7. Int J Biochem Cell Biol (2010) 0.78
A small sequence in the third intracellular loop of the VPAC(1) receptor is responsible for its efficient coupling to the calcium effector. Mol Endocrinol (2002) 0.78
Ribonucleotide reductase and thymidine phosphorylation: two potential targets of azodicarbonamide. Biochem Pharmacol (2002) 0.78
Pituitary adenylate cyclase activating peptide (PACAP) participates in adipogenesis by activating ERK signaling pathway. PLoS One (2013) 0.78
Expression of the aquaporin 8 water channel in a rat salivary epithelial cell. J Cell Physiol (2002) 0.78
Motilin and erythromycin-A share a common binding site in the third transmembrane segment of the motilin receptor. Biochem Pharmacol (2005) 0.78
Coexistence of non-adrenergic non-cholinergic inhibitory and excitatory neurotransmitters in a large neuronal subpopulation in the vaginal segment of the chicken oviduct. Auton Neurosci (2004) 0.77
Recombinant adenovirus administration in rat peritoneum: endothelial expression and safety concerns. Nephrol Dial Transplant (2004) 0.77
Expression of the electrogenic Na+-HCO3--cotransporters NBCe1-A and NBCe1-B in rat pancreatic islet cells. Endocrine (2009) 0.77
Synthesis and affinity studies of himbacine derived muscarinic receptor antagonists. Bioorg Med Chem Lett (2002) 0.77
Polymorphisms for ghrelin with consequences on satiety and metabolic alterations. Curr Opin Clin Nutr Metab Care (2014) 0.77
Evidence for a direct interaction between the Thr11 residue of vasoactive intestinal polypeptide and Tyr184 located in the first extracellular loop of the VPAC2 receptor. Biochem J (2003) 0.76
Contrasting effects of glycerol and urea transport on rat pancreatic beta-cell function. Cell Physiol Biochem (2009) 0.76
Aquaporin-4 as a potential marker of BBB disruption in ALS models. Amyotroph Lateral Scler (2010) 0.75
The neuropeptides vasoactive intestinal peptide (VIP) and pituitary adenylate cyclase activating polypeptide (PACAP) modulate several biochemical pathways in human leukemic myeloid cells. J Neuroimmunol (2004) 0.75
Ac His1 [D-Phe2, K15, R16, L27] VIP (3-7)/GRF (8-27)--a VPAC1 receptor antagonist--is an inverse agonist on two constitutively active truncated VPAC1 receptors. Peptides (2004) 0.75
A new role for aquaporin 7 in insulin secretion. Cell Physiol Biochem (2012) 0.75
Effect of IPs, cAMP, and cGMP on the hPL and hCG secretion from human term placenta. Mol Cell Endocrinol (2005) 0.75
VPAC(1) receptors have different agonist efficacy profiles on membrane and intact cells. Cell Signal (2002) 0.75
Effect of positive charge in VIP 16gamma-glutamyl diamino derivatives on hVPAC1 and hVPAC2 receptor function. J Pept Sci (2008) 0.75
Mutation of the phosphorylatable residue Thr429 in Glu of the human VPAC1 led to a constitutively desensitized receptor. Peptides (2006) 0.75
Transglutaminase-mediated polyamination of vasoactive intestinal peptide (VIP) Gln16 residue modulates VIP/PACAP receptor activity. Eur J Biochem (2002) 0.75