Published in J Biol Chem on December 29, 2003
The genetic design of signaling cascades to record receptor activation. Proc Natl Acad Sci U S A (2007) 3.11
Synthetic chemerin-derived peptides suppress inflammation through ChemR23. J Exp Med (2008) 2.54
Chemerin expression marks early psoriatic skin lesions and correlates with plasmacytoid dendritic cell recruitment. J Exp Med (2008) 1.67
Chemerin is a novel adipocyte-derived factor inducing insulin resistance in primary human skeletal muscle cells. Diabetes (2009) 1.59
Role of ChemR23 in directing the migration of myeloid and plasmacytoid dendritic cells to lymphoid organs and inflamed skin. J Exp Med (2005) 1.54
Conjunctival goblet cell secretion stimulated by leukotrienes is reduced by resolvins D1 and E1 to promote resolution of inflammation. J Immunol (2011) 1.23
Chemerin, a novel adipokine in the regulation of angiogenesis. J Clin Endocrinol Metab (2010) 1.20
Epithelial cells in fetal intestine produce chemerin to recruit macrophages. Am J Physiol Gastrointest Liver Physiol (2009) 1.11
Regulation of chemerin bioactivity by plasma carboxypeptidase N, carboxypeptidase B (activated thrombin-activable fibrinolysis inhibitor), and platelets. J Biol Chem (2008) 1.06
Chemerin reveals its chimeric nature. J Exp Med (2008) 1.06
Chemokine-like receptor 1 (CMKLR1) and chemokine (C-C motif) receptor-like 2 (CCRL2); two multifunctional receptors with unusual properties. Exp Cell Res (2010) 1.06
Update on leukotriene, lipoxin and oxoeicosanoid receptors: IUPHAR Review 7. Br J Pharmacol (2014) 1.03
CCL19 is a specific ligand of the constitutively recycling atypical human chemokine receptor CRAM-B. Immunology (2009) 1.02
Chemerin connects fat to arterial contraction. Arterioscler Thromb Vasc Biol (2013) 0.99
ChemR23 dampens lung inflammation and enhances anti-viral immunity in a mouse model of acute viral pneumonia. PLoS Pathog (2011) 0.99
Chemerin aggravates DSS-induced colitis by suppressing M2 macrophage polarization. Cell Mol Immunol (2014) 0.94
Proteolytic cleavage of chemerin protein is necessary for activation to the active form, Chem157S, which functions as a signaling molecule in glioblastoma. J Biol Chem (2011) 0.91
Proteolytic regulatory mechanism of chemerin bioactivity. Acta Biochim Biophys Sin (Shanghai) (2009) 0.90
Chemerin activates fibroblast-like synoviocytes in patients with rheumatoid arthritis. Arthritis Res Ther (2011) 0.89
The chemerin/ChemR23 system does not affect the pro-inflammatory response of mouse and human macrophages ex vivo. PLoS One (2012) 0.89
Microglial Aβ receptors in Alzheimer's disease. Cell Mol Neurobiol (2014) 0.86
Chemerin is an antimicrobial agent in human epidermis. PLoS One (2013) 0.86
Anti-TNF therapy reduces serum levels of chemerin in rheumatoid arthritis: a new mechanism by which anti-TNF might reduce inflammation. PLoS One (2013) 0.85
Chemerin: A comprehensive review elucidating the need for cardiovascular research. Pharmacol Res (2015) 0.83
Elastase and tryptase govern TNFα-mediated production of active chemerin by adipocytes. PLoS One (2012) 0.81
Chemerin-derived peptide C-20 suppressed gonadal steroidogenesis. Am J Reprod Immunol (2013) 0.78
Adipokines as potential biomarkers in rheumatoid arthritis. Mediators Inflamm (2014) 0.78
Evidence from studies in rodents and in isolated adipocytes that agonists of the chemerin receptor CMKLR1 may be beneficial in the treatment of type 2 diabetes. PeerJ (2015) 0.76
Signaling Properties of Chemerin Receptors CMKLR1, GPR1 and CCRL2. PLoS One (2016) 0.76
Chemerin C9 peptide induces receptor internalization through a clathrin-independent pathway. Acta Pharmacol Sin (2014) 0.76
Chemokine-Like Receptor 1 Regulates the Proliferation and Migration of Vascular Smooth Muscle Cells. Med Sci Monit (2016) 0.75
Physiological Roles of Adipokines, Hepatokines, and Myokines in Ruminants. Asian-Australas J Anim Sci (2016) 0.75
The adipokine chemerin amplifies electrical field-stimulated contraction in the isolated rat superior mesenteric artery. Am J Physiol Heart Circ Physiol (2016) 0.75
Molecular evolution of a peptide GPCR ligand driven by artificial neural networks. PLoS One (2012) 0.75
Development of a membrane-anchored chemerin receptor agonist as a novel modulator of allergic airway inflammation and neuropathic pain. J Biol Chem (2014) 0.75
Chemerin-ChemR23 signaling in tooth development. J Dent Res (2012) 0.75
Chemerin Elicits Potent Constrictor Actions via Chemokine-Like Receptor 1 (CMKLR1), not G-Protein-Coupled Receptor 1 (GPR1), in Human and Rat Vasculature. J Am Heart Assoc (2016) 0.75
Long-term treatment of rheumatoid arthritis with adalimumab. Open Access Rheumatol (2013) 0.75
CMKLR1 activation ex vivo does not increase proportionally to serum total chemerin in obese humans. Endocr Connect (2016) 0.75
Chemerin-induced arterial contraction is Gi- and calcium-dependent. Vascul Pharmacol (2016) 0.75
Biochemical and biophysical characterization of cytokine-like protein 1 (CYTL1). Cytokine (2017) 0.75
Functional characterization of human receptors for short chain fatty acids and their role in polymorphonuclear cell activation. J Biol Chem (2003) 4.79
Specific recruitment of antigen-presenting cells by chemerin, a novel processed ligand from human inflammatory fluids. J Exp Med (2003) 3.91
International Union of Basic and Clinical Pharmacology. LXXIII. Nomenclature for the formyl peptide receptor (FPR) family. Pharmacol Rev (2009) 3.65
Role of PlGF in the intra- and intermolecular cross talk between the VEGF receptors Flt1 and Flk1. Nat Med (2003) 3.17
International Union of Basic and Clinical Pharmacology. LXVII. Recommendations for the recognition and nomenclature of G protein-coupled receptor heteromultimers. Pharmacol Rev (2007) 2.62
Formyl peptide receptors: a promiscuous subfamily of G protein-coupled receptors controlling immune responses. Cytokine Growth Factor Rev (2006) 2.57
Glycoprotein hormone receptors: link between receptor homodimerization and negative cooperativity. EMBO J (2005) 2.16
Ovarian hyperstimulation syndrome due to a mutation in the follicle-stimulating hormone receptor. N Engl J Med (2003) 2.16
Discordance of monozygotic twins for thyroid dysgenesis: implications for screening and for molecular pathophysiology. J Clin Endocrinol Metab (2002) 2.00
Chemerin--a new adipokine that modulates adipogenesis via its own receptor. Biochem Biophys Res Commun (2007) 2.00
The role of chemerin in the colocalization of NK and dendritic cell subsets into inflamed tissues. Blood (2007) 1.99
CCR5 deficiency exacerbates T-cell-mediated hepatitis in mice. Hepatology (2005) 1.88
LGR5 deficiency deregulates Wnt signaling and leads to precocious Paneth cell differentiation in the fetal intestine. Dev Biol (2009) 1.75
Neutrophil-mediated maturation of chemerin: a link between innate and adaptive immunity. J Immunol (2005) 1.70
Evidence for negative binding cooperativity within CCR5-CCR2b heterodimers. Mol Pharmacol (2004) 1.69
Prediction of severity of symptoms in iatrogenic ovarian hyperstimulation syndrome by follicle-stimulating hormone receptor Ser680Asn polymorphism. J Clin Endocrinol Metab (2004) 1.67
Chemerin expression marks early psoriatic skin lesions and correlates with plasmacytoid dendritic cell recruitment. J Exp Med (2008) 1.67
Involvement of CB1 cannabinoid receptors in emotional behaviour. Psychopharmacology (Berl) (2001) 1.57
Defective postnatal development of the male reproductive tract in LGR4 knockout mice. Dev Biol (2006) 1.56
Hetero-oligomerization of CCR2, CCR5, and CXCR4 and the protean effects of "selective" antagonists. J Biol Chem (2009) 1.55
Revascularization of ischemic tissues by PDGF-CC via effects on endothelial cells and their progenitors. J Clin Invest (2005) 1.55
Ghrelin degradation by serum and tissue homogenates: identification of the cleavage sites. Endocrinology (2004) 1.55
Role of ChemR23 in directing the migration of myeloid and plasmacytoid dendritic cells to lymphoid organs and inflamed skin. J Exp Med (2005) 1.54
Non-peptide arginine-vasopressin antagonists: the vaptans. Lancet (2008) 1.54
Activation of the cAMP pathway by the TSH receptor involves switching of the ectodomain from a tethered inverse agonist to an agonist. Mol Endocrinol (2002) 1.51
Chromosomal translocations as a mechanism of BRAF activation in two cases of large congenital melanocytic nevi. J Invest Dermatol (2007) 1.48
Predominance of aqueous Tl(I) species in the river system downstream from the abandoned Carnoulès mine (Southern France). Environ Sci Technol (2011) 1.47
Lgr4 is required for Paneth cell differentiation and maintenance of intestinal stem cells ex vivo. EMBO Rep (2011) 1.47
Allosteric modulation of binding properties between units of chemokine receptor homo- and hetero-oligomers. Mol Pharmacol (2006) 1.47
The core domain of chemokines binds CCR5 extracellular domains while their amino terminus interacts with the transmembrane helix bundle. J Biol Chem (2002) 1.46
Mouse ChemR23 is expressed in dendritic cell subsets and macrophages, and mediates an anti-inflammatory activity of chemerin in a lung disease model. J Immunol (2009) 1.45
Allosteric transinhibition by specific antagonists in CCR2/CXCR4 heterodimers. J Biol Chem (2007) 1.45
Constitutive agonist-independent CCR5 oligomerization and antibody-mediated clustering occurring at physiological levels of receptors. J Biol Chem (2002) 1.44
Premature ovarian aging in mice deficient for Gpr3. Proc Natl Acad Sci U S A (2005) 1.41
Lack of CB1 cannabinoid receptor impairs cocaine self-administration. Neuropsychopharmacology (2005) 1.41
Pharmacological characterization of the human P2Y13 receptor. Mol Pharmacol (2003) 1.40
Multiple active states and oligomerization of CCR5 revealed by functional properties of monoclonal antibodies. Mol Biol Cell (2002) 1.39
Allosteric properties of G protein-coupled receptor oligomers. Pharmacol Ther (2007) 1.39
Nephrogenic syndrome of inappropriate antidiuresis in adults: high phenotypic variability in men and women from a large pedigree. J Am Soc Nephrol (2007) 1.38
Glycoprotein hormone receptors: determinants in leucine-rich repeats responsible for ligand specificity. EMBO J (2003) 1.35
Drosophila molting neurohormone bursicon is a heterodimer and the natural agonist of the orphan receptor DLGR2. FEBS Lett (2005) 1.35
G protein-dependent CCR5 signaling is not required for efficient infection of primary T lymphocytes and macrophages by R5 human immunodeficiency virus type 1 isolates. J Virol (2003) 1.30
Plasmacytoid dendritic cells in multiple sclerosis: intracerebral recruitment and impaired maturation in response to interferon-beta. J Neuropathol Exp Neurol (2008) 1.29
Activation of dual oxidases Duox1 and Duox2: differential regulation mediated by camp-dependent protein kinase and protein kinase C-dependent phosphorylation. J Biol Chem (2009) 1.29
Synergy between coproduced CC and CXC chemokines in monocyte chemotaxis through receptor-mediated events. Mol Pharmacol (2008) 1.29
Chemerin and its receptors in leukocyte trafficking, inflammation and metabolism. Cytokine Growth Factor Rev (2011) 1.28
A lack of thyroid hormones rather than excess thyrotropin causes abnormal skeletal development in hypothyroidism. Mol Endocrinol (2007) 1.27
Genetics of resistance to HIV infection: Role of co-receptors and co-receptor ligands. Semin Immunol (2006) 1.24
Identification of nonpeptide CCR5 receptor agonists by structure-based virtual screening. J Med Chem (2007) 1.23
Characterization of a novel loss of function mutation of PAX8 in a familial case of congenital hypothyroidism with in-place, normal-sized thyroid. J Clin Endocrinol Metab (2004) 1.21
GRIS: glycoprotein-hormone receptor information system. Mol Endocrinol (2006) 1.21
RF9, a potent and selective neuropeptide FF receptor antagonist, prevents opioid-induced tolerance associated with hyperalgesia. Proc Natl Acad Sci U S A (2006) 1.19
Dimerization of chemokine receptors and its functional consequences. Cytokine Growth Factor Rev (2005) 1.19
Expression pattern of the orphan receptor LGR4/GPR48 gene in the mouse. Histochem Cell Biol (2005) 1.18
Citrullination of CXCL12 differentially reduces CXCR4 and CXCR7 binding with loss of inflammatory and anti-HIV-1 activity via CXCR4. J Immunol (2009) 1.15
Identification and characterization of an endogenous chemotactic ligand specific for FPRL2. J Exp Med (2004) 1.14
Distinct recognition of OX1 and OX2 receptors by orexin peptides. J Pharmacol Exp Ther (2003) 1.13
Activation of CCR5 by chemokines involves an aromatic cluster between transmembrane helices 2 and 3. J Biol Chem (2002) 1.13
Mutation of the DRY motif reveals different structural requirements for the CC chemokine receptor 5-mediated signaling and receptor endocytosis. Mol Pharmacol (2005) 1.12
Proteolytic processing of CXCL11 by CD13/aminopeptidase N impairs CXCR3 and CXCR7 binding and signaling and reduces lymphocyte and endothelial cell migration. Blood (2007) 1.09
GPCR-OKB: the G Protein Coupled Receptor Oligomer Knowledge Base. Bioinformatics (2010) 1.09
Small neutralizing molecules to inhibit actions of the chemokine CXCL12. J Biol Chem (2008) 1.08
An activation switch in the rhodopsin family of G protein-coupled receptors: the thyrotropin receptor. J Biol Chem (2005) 1.08
F2L, a peptide derived from heme-binding protein, chemoattracts mouse neutrophils by specifically activating Fpr2, the low-affinity N-formylpeptide receptor. J Immunol (2007) 1.08
Understanding ovarian hyperstimulation syndrome. Endocrine (2005) 1.07
Murine 3T3-L1 adipocyte cell differentiation model: validated reference genes for qPCR gene expression analysis. PLoS One (2012) 1.06
CCR8-dependent activation of the RAS/MAPK pathway mediates anti-apoptotic activity of I-309/ CCL1 and vMIP-I. Eur J Immunol (2003) 1.06
Ectopic thyroid gland causing dysphonia: imaging and molecular studies. J Clin Endocrinol Metab (2010) 1.04
Requirements and ontology for a G protein-coupled receptor oligomerization knowledge base. BMC Bioinformatics (2007) 1.04
Structural differences in the hinge region of the glycoprotein hormone receptors: evidence from the sulfated tyrosine residues. Mol Endocrinol (2006) 1.04
Age-related changes of anandamide metabolism in CB1 cannabinoid receptor knockout mice: correlation with behaviour. Eur J Neurosci (2002) 1.04
Thyroid transcription factor 1 rescues PAX8/p300 synergism impaired by a natural PAX8 paired domain mutation with dominant negative activity. Mol Endocrinol (2005) 1.03
Identification of natural ligands for the orphan G protein-coupled receptors GPR7 and GPR8. J Biol Chem (2002) 1.03
Delineation of the discontinuous-conformational epitope of a monoclonal antibody displaying full in vitro and in vivo thyrotropin activity. Mol Endocrinol (2004) 1.02
Formyl peptide receptor-like 2 is expressed and functional in plasmacytoid dendritic cells, tissue-specific macrophage subpopulations, and eosinophils. J Immunol (2009) 1.02
Identification of Lgr5-independent spheroid-generating progenitors of the mouse fetal intestinal epithelium. Cell Rep (2013) 1.02
Angiostatic and chemotactic activities of the CXC chemokine CXCL4L1 (platelet factor-4 variant) are mediated by CXCR3. Blood (2010) 1.02
Thrombospondin-1 and indoleamine 2,3-dioxygenase are major targets of extracellular ATP in human dendritic cells. Blood (2005) 1.02
Identification of fructosamine residues deglycated by fructosamine-3-kinase in human hemoglobin. J Biol Chem (2004) 1.01
Novel, not adenylyl cyclase-coupled cannabinoid binding site in cerebellum of mice. Biochem Biophys Res Commun (2002) 1.01