| Rank |
Title |
Journal |
Year |
PubWeight™‹?› |
|
1
|
Small-molecule antagonists of the oncogenic Tcf/beta-catenin protein complex.
|
Cancer Cell
|
2004
|
4.98
|
|
2
|
Small molecule blockade of transcriptional coactivation of the hypoxia-inducible factor pathway.
|
Cancer Cell
|
2004
|
3.43
|
|
3
|
Selective and specific inhibition of the plasmodium falciparum lysyl-tRNA synthetase by the fungal secondary metabolite cladosporin.
|
Cell Host Microbe
|
2012
|
2.05
|
|
4
|
Spirotetrahydro beta-carbolines (spiroindolones): a new class of potent and orally efficacious compounds for the treatment of malaria.
|
J Med Chem
|
2010
|
1.84
|
|
5
|
Structure and vascularization of the acetabular labrum with regard to the pathogenesis and healing of labral lesions.
|
Arch Orthop Trauma Surg
|
2003
|
1.30
|
|
6
|
Lipiarmycin targets RNA polymerase and has good activity against multidrug-resistant strains of Mycobacterium tuberculosis.
|
J Antimicrob Chemother
|
2008
|
1.28
|
|
7
|
Platelet-derived chemokines in vascular biology.
|
Thromb Haemost
|
2007
|
1.27
|
|
8
|
Retracted
Extracellular ATP induces cytokine expression and apoptosis through P2X7 receptor in murine mast cells.
|
J Immunol
|
2005
|
1.16
|
|
9
|
The high-resolution solution structure of epothilone A bound to tubulin: an understanding of the structure-activity relationships for a powerful class of antitumor agents.
|
Angew Chem Int Ed Engl
|
2003
|
1.09
|
|
10
|
Drug discovery from natural products.
|
J Ind Microbiol Biotechnol
|
2006
|
1.07
|
|
11
|
Platelet factor 4/CXCL4-stimulated human monocytes induce apoptosis in endothelial cells by the release of oxygen radicals.
|
J Leukoc Biol
|
2008
|
1.05
|
|
12
|
Platelet-derived chemokines CXC chemokine ligand (CXCL)7, connective tissue-activating peptide III, and CXCL4 differentially affect and cross-regulate neutrophil adhesion and transendothelial migration.
|
J Immunol
|
2002
|
1.04
|
|
13
|
Platelet factor 4 inhibits proliferation and cytokine release of activated human T cells.
|
J Immunol
|
2002
|
1.02
|
|
14
|
Argyrins, immunosuppressive cyclic peptides from myxobacteria. I. Production, isolation, physico-chemical and biological properties.
|
J Antibiot (Tokyo)
|
2002
|
1.00
|
|
15
|
Platelet factor 4/CXCL4 induces phagocytosis and the generation of reactive oxygen metabolites in mononuclear phagocytes independently of Gi protein activation or intracellular calcium transients.
|
J Immunol
|
2004
|
0.97
|
|
16
|
Molecular pathways of platelet factor 4/CXCL4 signaling.
|
Eur J Cell Biol
|
2011
|
0.94
|
|
17
|
Platelet factor 4 in conjunction with IL-4 directs differentiation of human monocytes into specialized antigen-presenting cells.
|
FASEB J
|
2004
|
0.93
|
|
18
|
Platelet factor 4 (PF-4)-induced neutrophil adhesion is controlled by src-kinases, whereas PF-4-mediated exocytosis requires the additional activation of p38 MAP kinase and phosphatidylinositol 3-kinase.
|
Blood
|
2003
|
0.92
|
|
19
|
Platelet factor 4 (CXC chemokine ligand 4) differentially regulates respiratory burst, survival, and cytokine expression of human monocytes by using distinct signaling pathways.
|
J Immunol
|
2007
|
0.92
|
|
20
|
Meta-analysis reveals an association of STAT4 polymorphisms with systemic autoimmune disorders and anti-dsDNA antibody.
|
Hum Immunol
|
2013
|
0.90
|
|
21
|
The cathelicidin LL-37 activates human mast cells and is degraded by mast cell tryptase: counter-regulation by CXCL4.
|
J Immunol
|
2009
|
0.88
|
|
22
|
Mechanisms of cilia-driven transport in the airways in the absence of mucus.
|
Am J Respir Cell Mol Biol
|
2014
|
0.88
|
|
23
|
Interaction of epothilone B (patupilone) with microtubules as detected by two-dimensional solid-state NMR spectroscopy.
|
Angew Chem Int Ed Engl
|
2010
|
0.88
|
|
24
|
Neutrophil adhesion to endothelial cells induced by platelet factor 4 requires sequential activation of Ras, Syk, and JNK MAP kinases.
|
Blood
|
2005
|
0.87
|
|
25
|
Mast cells and neutrophils proteolytically activate chemokine precursor CTAP-III and are subject to counterregulation by PF-4 through inhibition of chymase and cathepsin G.
|
Blood
|
2005
|
0.86
|
|
26
|
Natural products as catalysts for innovation: a pharmaceutical industry perspective.
|
Curr Opin Chem Biol
|
2011
|
0.86
|
|
27
|
Mast cells and fibroblasts work in concert to aggravate pulmonary fibrosis: role of transmembrane SCF and the PAR-2/PKC-α/Raf-1/p44/42 signaling pathway.
|
Am J Pathol
|
2013
|
0.85
|
|
28
|
CXC chemokine ligand 4 (CXCL4) down-regulates CC chemokine receptor expression on human monocytes.
|
Innate Immun
|
2010
|
0.84
|
|
29
|
FcγRIIA and FcγRIIIB are required for autoantibody-induced tissue damage in experimental human models of bullous pemphigoid.
|
J Invest Dermatol
|
2010
|
0.81
|
|
30
|
Euphohelioscopin A is a PKC activator capable of inducing macrophage differentiation.
|
Chem Biol
|
2012
|
0.79
|
|
31
|
High-resolution solid-state NMR structure of an anticancer agent.
|
ChemMedChem
|
2007
|
0.78
|
|
32
|
Effect of antimicrobial peptides from Apis mellifera hemolymph and its optimized version Api88 on biological activities of human monocytes and mast cells.
|
Innate Immun
|
2012
|
0.77
|
|
33
|
The CXC chemokine NAP-2 mediates differential heterologous desensitization of neutrophil effector functions elicited by platelet-activating factor.
|
J Interferon Cytokine Res
|
2002
|
0.76
|
|
34
|
CXCL4-induced monocyte survival, cytokine expression, and oxygen radical formation is regulated by sphingosine kinase 1.
|
Eur J Immunol
|
2010
|
0.76
|
|
35
|
A novel preclinical model for rheumatoid arthritis research.
|
Arthritis Res Ther
|
2010
|
0.75
|
|
36
|
Retraction: Extracellular ATP induces cytokine expression and apoptosis through P2X7 receptor in murine mast cells.
|
J Immunol
|
2011
|
0.75
|
|
37
|
Eupalinilide E inhibits erythropoiesis and promotes the expansion of hematopoietic progenitor cells.
|
ACS Chem Biol
|
2013
|
0.75
|