Published in Curr Opin Cell Biol on August 01, 2004
The conserved Bardet-Biedl syndrome proteins assemble a coat that traffics membrane proteins to cilia. Cell (2010) 3.83
The hydrophobic insertion mechanism of membrane curvature generation by proteins. Biophys J (2008) 2.98
Endophilin BAR domain drives membrane curvature by two newly identified structure-based mechanisms. EMBO J (2006) 2.98
Role of the AP2 beta-appendage hub in recruiting partners for clathrin-coated vesicle assembly. PLoS Biol (2006) 2.71
Structure of coatomer cage proteins and the relationship among COPI, COPII, and clathrin vesicle coats. Cell (2010) 2.59
Insights into COPII coat nucleation from the structure of Sec23.Sar1 complexed with the active fragment of Sec31. Dev Cell (2007) 2.42
ArfGAP1 responds to membrane curvature through the folding of a lipid packing sensor motif. EMBO J (2005) 2.37
Sorting nexins provide diversity for retromer-dependent trafficking events. Nat Cell Biol (2011) 2.32
Lipid droplets: a classic organelle with new outfits. Histochem Cell Biol (2008) 2.22
Hide and run. Arginine-based endoplasmic-reticulum-sorting motifs in the assembly of heteromultimeric membrane proteins. EMBO Rep (2005) 2.04
Four-scale description of membrane sculpting by BAR domains. Biophys J (2008) 2.00
Conserved functions of membrane active GTPases in coated vesicle formation. Science (2009) 1.90
Multiple mechanisms collectively regulate clathrin-mediated endocytosis of the epidermal growth factor receptor. J Cell Biol (2010) 1.90
An elaborate classification of SNARE proteins sheds light on the conservation of the eukaryotic endomembrane system. Mol Biol Cell (2007) 1.89
Imaging endocytic clathrin structures in living cells. Trends Cell Biol (2009) 1.86
Hippocalcin functions as a calcium sensor in hippocampal LTD. Neuron (2005) 1.58
Factors influencing local membrane curvature induction by N-BAR domains as revealed by molecular dynamics simulations. Biophys J (2008) 1.53
Structure-function mapping of a heptameric module in the nuclear pore complex. J Cell Biol (2012) 1.44
Membrane insertion of the pleckstrin homology domain variable loop 1 is critical for dynamin-catalyzed vesicle scission. Mol Biol Cell (2009) 1.42
Phosphorylation of a membrane curvature-sensing motif switches function of the HOPS subunit Vps41 in membrane tethering. J Cell Biol (2010) 1.34
COPI budding within the Golgi stack. Cold Spring Harb Perspect Biol (2011) 1.33
Transport according to GARP: receiving retrograde cargo at the trans-Golgi network. Trends Cell Biol (2010) 1.32
GTPase activity and neuronal toxicity of Parkinson's disease-associated LRRK2 is regulated by ArfGAP1. PLoS Genet (2012) 1.29
Involvement of specific COPI subunits in protein sorting from the late endosome to the vacuole in yeast. Mol Cell Biol (2006) 1.24
Membrane-bending mechanism of amphiphysin N-BAR domains. Biophys J (2009) 1.23
Molecular mechanism of mitotic Golgi disassembly and reassembly revealed by a defined reconstitution assay. J Biol Chem (2007) 1.19
Large Arf1 guanine nucleotide exchange factors: evolution, domain structure, and roles in membrane trafficking and human disease. Mol Genet Genomics (2009) 1.18
Death-receptor activation halts clathrin-dependent endocytosis. Proc Natl Acad Sci U S A (2006) 1.18
The cellular functions of clathrin. Cell Mol Life Sci (2006) 1.17
The Gcs1 Arf-GAP mediates Snc1,2 v-SNARE retrieval to the Golgi in yeast. Mol Biol Cell (2006) 1.17
HOPS interacts with Apl5 at the vacuole membrane and is required for consumption of AP-3 transport vesicles. Mol Biol Cell (2009) 1.16
At the crossroads of homoeostasis and disease: roles of the PACS proteins in membrane traffic and apoptosis. Biochem J (2009) 1.15
The evolving understanding of COPI vesicle formation. Nat Rev Mol Cell Biol (2009) 1.14
Somatic cytokinesis and pollen maturation in Arabidopsis depend on TPLATE, which has domains similar to coat proteins. Plant Cell (2006) 1.10
A novel mRNA affinity purification technique for the identification of interacting proteins and transcripts in ribonucleoprotein complexes. RNA (2010) 1.10
Genetic reconstitution of the human adenovirus type 2 temperature-sensitive 1 mutant defective in endosomal escape. Virol J (2009) 1.07
A role for the host coatomer and KDEL receptor in early vaccinia biogenesis. Proc Natl Acad Sci U S A (2008) 1.05
Computational model explains high activity and rapid cycling of Rho GTPases within protein complexes. PLoS Comput Biol (2006) 1.04
Nuclear pore complex-a coat specifically tailored for the nuclear envelope. Curr Opin Cell Biol (2011) 1.01
Membrane sculpting by F-BAR domains studied by molecular dynamics simulations. PLoS Comput Biol (2013) 1.00
Reliable reference genes for normalization of gene expression in cucumber grown under different nitrogen nutrition. PLoS One (2013) 0.99
Btn2, a Hook1 ortholog and potential Batten disease-related protein, mediates late endosome-Golgi protein sorting in yeast. Mol Cell Biol (2006) 0.99
Comparative analyses of Legionella species identifies genetic features of strains causing Legionnaires' disease. Genome Biol (2014) 0.98
A conserved motif in transmembrane helix 1 of diphtheria toxin mediates catalytic domain delivery to the cytosol. Proc Natl Acad Sci U S A (2005) 0.97
Dimerization and direct membrane interaction of Nup53 contribute to nuclear pore complex assembly. EMBO J (2012) 0.96
gammaCOP is required for apical protein secretion and epithelial morphogenesis in Drosophila melanogaster. PLoS One (2008) 0.96
Cavin family proteins and the assembly of caveolae. J Cell Sci (2015) 0.96
Heterogeneity of leucine-rich repeat kinase 2 mutations: genetics, mechanisms and therapeutic implications. Neurotherapeutics (2014) 0.94
Functional roles of short sequence motifs in the endocytosis of membrane receptors. Front Biosci (Landmark Ed) (2009) 0.94
The TOR complex 1 is distributed in endosomes and in retrograde vesicles that form from the vacuole membrane and plays an important role in the vacuole import and degradation pathway. J Biol Chem (2010) 0.94
ARFGAP1 promotes AP-2-dependent endocytosis. Nat Cell Biol (2011) 0.94
Mutation in archain 1, a subunit of COPI coatomer complex, causes diluted coat color and Purkinje cell degeneration. PLoS Genet (2010) 0.92
Subcellular trafficking of the substrate transporters GLUT4 and CD36 in cardiomyocytes. Cell Mol Life Sci (2011) 0.92
Intraflagellar transport: a new player at the immune synapse. Trends Immunol (2011) 0.91
Bending "on the rocks"--a cocktail of biophysical modules to build endocytic pathways. Cold Spring Harb Perspect Biol (2014) 0.91
Dimeric endophilin A2 stimulates assembly and GTPase activity of dynamin 2. Biophys J (2011) 0.91
Kinetic regulation of coated vesicle secretion. Proc Natl Acad Sci U S A (2008) 0.90
Dopamine receptor D3 regulates endocytic sorting by a Prazosin-sensitive interaction with the coatomer COPI. Proc Natl Acad Sci U S A (2012) 0.89
Disruption of kv1.3 channel forward vesicular trafficking by hypoxia in human T lymphocytes. J Biol Chem (2011) 0.89
Several ADP-ribosylation factor (Arf) isoforms support COPI vesicle formation. J Biol Chem (2011) 0.89
Conserved and plant-unique mechanisms regulating plant post-Golgi traffic. Front Plant Sci (2012) 0.89
Small peptide recognition sequence for intracellular sorting. Curr Opin Biotechnol (2010) 0.87
Molecular structure and flexibility of the yeast coatomer as revealed by electron microscopy. J Mol Biol (2011) 0.86
A selective autophagy pathway that degrades gluconeogenic enzymes during catabolite inactivation. Commun Integr Biol (2009) 0.85
New organelles by gene duplication in a biophysical model of eukaryote endomembrane evolution. Biophys J (2013) 0.84
Loss of yata, a novel gene regulating the subcellular localization of APPL, induces deterioration of neural tissues and lifespan shortening. PLoS One (2009) 0.84
AlphaB-crystallin: a Golgi-associated membrane protein in the developing ocular lens. Invest Ophthalmol Vis Sci (2009) 0.84
Endosomal sorting by Semaphorin 4A in retinal pigment epithelium supports photoreceptor survival. Genes Dev (2012) 0.84
Synaptotagmin's role in neurotransmitter release likely involves Ca(2+)-induced conformational transition. Biophys J (2014) 0.84
Structural disorder provides increased adaptability for vesicle trafficking pathways. PLoS Comput Biol (2013) 0.83
Fine mapping of a region of chromosome 11q23.3 reveals independent locus associated with risk of glioma. PLoS One (2012) 0.81
Scalable production in human cells and biochemical characterization of full-length normal and mutant huntingtin. PLoS One (2015) 0.80
Following the fate in vivo of COPI vesicles generated in vitro. Traffic (2009) 0.80
Mutational analysis of betaCOP (Sec26p) identifies an appendage domain critical for function. BMC Cell Biol (2008) 0.79
Evolution of insect proteomes: insights into synapse organization and synaptic vesicle life cycle. Genome Biol (2008) 0.79
Validation of endogenous reference genes in Buglossoides arvensis for normalizing RT-qPCR-based gene expression data. Springerplus (2015) 0.79
Adenovirus RID-alpha activates an autonomous cholesterol regulatory mechanism that rescues defects linked to Niemann-Pick disease type C. J Cell Biol (2009) 0.78
Poly-L-lysine-induced morphology changes in mixed anionic/zwitterionic and neat zwitterionic-supported phospholipid bilayers. Biophys J (2006) 0.78
Live-cell imaging of clathrin coats. Methods Enzymol (2012) 0.78
Tetrahymena thermophila: a divergent perspective on membrane traffic. J Exp Zool B Mol Dev Evol (2014) 0.77
Pinpointing retrovirus entry sites in cells expressing alternatively spliced receptor isoforms by single virus imaging. Retrovirology (2014) 0.77
Structural and molecular bases of rod photoreceptor morphogenesis and disease. Prog Retin Eye Res (2016) 0.76
Shape and energy of a membrane bud induced by protein coats or viral protein assembly. Eur Phys J E Soft Matter (2014) 0.76
Dynamin-related proteins in plant post-Golgi traffic. Front Plant Sci (2014) 0.76
Vacuole import and degradation pathway: Insights into a specialized autophagy pathway. World J Biol Chem (2011) 0.76
Midgut proteome of an argasid tick, Ornithodoros erraticus: a comparison between unfed and engorged females. Parasit Vectors (2015) 0.75
Sorting protein VPS33B regulates exosomal autocrine signaling to mediate hematopoiesis and leukemogenesis. J Clin Invest (2016) 0.75
Genetic Evidence for the Role of the Vacuole in Supplying Secretory Organelles with Ca2+ in Hansenula polymorpha. PLoS One (2015) 0.75
The Energy of COPI for Budding Membranes. PLoS One (2015) 0.75
Endocytosis and Trafficking of Natriuretic Peptide Receptor-A: Potential Role of Short Sequence Motifs. Membranes (Basel) (2015) 0.75
Membrane deformation and separation. F1000 Biol Rep (2010) 0.75
Identification of Newly Synthesized Proteins by Echinococcus granulosus Protoscoleces upon Induction of Strobilation. PLoS Negl Trop Dis (2015) 0.75
A Novel Type III Endosome Transmembrane Protein, TEMP. Cells (2012) 0.75
Bioinformatic indications that COPI- and clathrin-based transport systems are not present in chloroplasts: an Arabidopsis model. PLoS One (2014) 0.75
Structure of Golgi transport proteins. Cold Spring Harb Perspect Biol (2011) 0.75
BAR domains as sensors of membrane curvature: the amphiphysin BAR structure. Science (2003) 12.60
Curvature of clathrin-coated pits driven by epsin. Nature (2002) 8.03
Principles for the post-GWAS functional characterization of cancer risk loci. Nat Genet (2011) 3.73
The androgen receptor fuels prostate cancer by regulating central metabolism and biosynthesis. EMBO J (2011) 2.97
Role of the AP2 beta-appendage hub in recruiting partners for clathrin-coated vesicle assembly. PLoS Biol (2006) 2.71
The androgen receptor induces a distinct transcriptional program in castration-resistant prostate cancer in man. Cancer Cell (2012) 2.59
New androgen receptor genomic targets show an interaction with the ETS1 transcription factor. EMBO Rep (2007) 2.17
Thiol isomerases negatively regulate the cellular shedding activity of ADAM17. Biochem J (2010) 1.93
Evolving nature of the AP2 alpha-appendage hub during clathrin-coated vesicle endocytosis. EMBO J (2004) 1.87
ER stress-mediated autophagy promotes Myc-dependent transformation and tumor growth. J Clin Invest (2012) 1.85
Androgen receptor driven transcription in molecular apocrine breast cancer is mediated by FoxA1. EMBO J (2011) 1.72
Clathrin adaptor epsinR is required for retrograde sorting on early endosomal membranes. Dev Cell (2004) 1.62
Exome sequencing of prostate cancer supports the hypothesis of independent tumour origins. Eur Urol (2012) 1.60
ChIPping away at gene regulation. EMBO Rep (2008) 1.54
Structural basis for the nuclear import of the human androgen receptor. J Cell Sci (2008) 1.53
Abundant genetic overlap between blood lipids and immune-mediated diseases indicates shared molecular genetic mechanisms. PLoS One (2015) 1.48
LYRIC/AEG-1 is targeted to different subcellular compartments by ubiquitinylation and intrinsic nuclear localization signals. Clin Cancer Res (2009) 1.41
O-GlcNAc transferase integrates metabolic pathways to regulate the stability of c-MYC in human prostate cancer cells. Cancer Res (2013) 1.31
The developing role of receptors and adaptors. Nat Rev Cancer (2006) 1.21
A new look towards BAC-based array CGH through a comprehensive comparison with oligo-based array CGH. BMC Genomics (2007) 1.17
Alterations in beta-catenin expression and localization in prostate cancer. Prostate (2008) 1.16
The mitochondrial and autosomal mutation landscapes of prostate cancer. Eur Urol (2012) 1.12
Promoter methylation correlates with reduced Smad4 expression in advanced prostate cancer. Prostate (2008) 1.08
Molecular subtyping of primary prostate cancer reveals specific and shared target genes of different ETS rearrangements. Neoplasia (2012) 1.03
PIAS1 is increased in human prostate cancer and enhances proliferation through inhibition of p21. Am J Pathol (2012) 1.02
HES6 drives a critical AR transcriptional programme to induce castration-resistant prostate cancer through activation of an E2F1-mediated cell cycle network. EMBO Mol Med (2014) 0.98
Pro-neural transcription factors as cancer markers. BMC Med Genomics (2008) 0.97
Tumor necrosis factor receptor expression and signaling in renal cell carcinoma. Am J Pathol (2010) 0.95
Elevated NCOR1 disrupts a network of dietary-sensing nuclear receptors in bladder cancer cells. Carcinogenesis (2009) 0.94
Disseminated tumor cells and their prognostic significance in nonmetastatic prostate cancer patients. Int J Cancer (2013) 0.90
A role for neurotensin in bicalutamide resistant prostate cancer cells. Prostate (2007) 0.89
Solitary and repetitive binding motifs for the AP2 complex alpha-appendage in amphiphysin and other accessory proteins. J Biol Chem (2007) 0.88
Nuclear trafficking and functions of endocytic proteins implicated in oncogenesis. Traffic (2009) 0.83
Global identification of androgen response elements. Methods Mol Biol (2011) 0.83
N-linked glycosylation supports cross-talk between receptor tyrosine kinases and androgen receptor. PLoS One (2013) 0.82
Clathrin is spindle-associated but not essential for mitosis. PLoS One (2008) 0.82
Chromatin immunoprecipitation (ChIP) methodology and readouts. Methods Mol Biol (2009) 0.81
Chromatin binding by the androgen receptor in prostate cancer. Mol Cell Endocrinol (2011) 0.80
Putting chromatin immunoprecipitation into context. J Cell Biochem (2009) 0.79
Novel role of androgens in mitochondrial fission and apoptosis. Mol Cancer Res (2011) 0.78
AURKA overexpression accompanies dysregulation of DNA-damage response genes in invasive urothelial cell carcinoma. Cell Cycle (2008) 0.77
Terminal and progenitor lineage-survival oncogenes as cancer markers. Trends Mol Med (2008) 0.77
Mapping protein-DNA interactions using ChIP-sequencing. Methods Mol Biol (2012) 0.76
Bridging the gaps: from risk loci via non-coding RNAs to gene networks and prostate cancer phenotypes. Cell Cycle (2011) 0.75
Correction: Abundant Genetic Overlap between Blood Lipids and Immune-Mediated Diseases Indicates Shared Molecular Genetic Mechanisms. PLoS One (2015) 0.75
Studying N-linked glycosylation of receptor tyrosine kinases. Methods Mol Biol (2015) 0.75