PubRank

Burkhard Rost

Author PubWeight™ 212.56‹?›

Top papers

Rank Title Journal Year PubWeight™‹?›
1 SNAP predicts effect of mutations on protein function. Bioinformatics 2008 15.39
2 SNAP: predict effect of non-synonymous polymorphisms on function. Nucleic Acids Res 2007 8.46
3 Improving the prediction of protein secondary structure in three and eight classes using recurrent neural networks and profiles. Proteins 2002 5.29
4 A large-scale evaluation of computational protein function prediction. Nat Methods 2013 4.61
5 A mutation in VPS35, encoding a subunit of the retromer complex, causes late-onset Parkinson disease. Am J Hum Genet 2011 4.52
6 Critical assessment of methods of protein structure prediction-Round VII. Proteins 2007 3.23
7 Mimicking cellular sorting improves prediction of subcellular localization. J Mol Biol 2005 3.21
8 Three-dimensional structures of membrane proteins from genomic sequencing. Cell 2012 3.02
9 Analysing six types of protein-protein interfaces. J Mol Biol 2003 2.96
10 Critical assessment of methods of protein structure prediction (CASP)--round 6. Proteins 2005 2.58
11 Alignments grow, secondary structure prediction improves. Proteins 2002 2.56
12 EVA: Evaluation of protein structure prediction servers. Nucleic Acids Res 2003 2.50
13 Reliability of assessment of protein structure prediction methods. Structure 2002 2.39
14 Sequence conserved for subcellular localization. Protein Sci 2002 2.36
15 Automatic target selection for structural genomics on eukaryotes. Proteins 2004 2.34
16 Outcome of a workshop on archiving structural models of biological macromolecules. Structure 2006 2.32
17 The protein target list of the Northeast Structural Genomics Consortium. Proteins 2004 2.31
18 Transmembrane helix predictions revisited. Protein Sci 2002 2.28
19 Critical assessment of methods of protein structure prediction - Round VIII. Proteins 2009 2.25
20 Protein-protein interaction hotspots carved into sequences. PLoS Comput Biol 2007 2.15
21 PROFbval: predict flexible and rigid residues in proteins. Bioinformatics 2006 2.04
22 Domains, motifs and clusters in the protein universe. Curr Opin Chem Biol 2003 2.02
23 Predicted protein-protein interaction sites from local sequence information. FEBS Lett 2003 2.00
24 Loopy proteins appear conserved in evolution. J Mol Biol 2002 1.96
25 PSI-2: structural genomics to cover protein domain family space. Structure 2009 1.92
26 Protein names precisely peeled off free text. Bioinformatics 2004 1.87
27 Predicting transmembrane beta-barrels in proteomes. Nucleic Acids Res 2004 1.83
28 Distinguishing protein-coding from non-coding RNAs through support vector machines. PLoS Genet 2006 1.81
29 NLSdb: database of nuclear localization signals. Nucleic Acids Res 2003 1.81
30 PROFcon: novel prediction of long-range contacts. Bioinformatics 2005 1.81
31 UniqueProt: Creating representative protein sequence sets. Nucleic Acids Res 2003 1.78
32 Understanding the physical properties that control protein crystallization by analysis of large-scale experimental data. Nat Biotechnol 2009 1.78
33 Comprehensive in silico mutagenesis highlights functionally important residues in proteins. Bioinformatics 2008 1.74
34 Prediction of DNA-binding residues from sequence. Bioinformatics 2007 1.72
35 ISIS: interaction sites identified from sequence. Bioinformatics 2007 1.71
36 Epitome: database of structure-inferred antigenic epitopes. Nucleic Acids Res 2006 1.70
37 Improved disorder prediction by combination of orthogonal approaches. PLoS One 2009 1.63
38 Continuum secondary structure captures protein flexibility. Structure 2002 1.63
39 Better prediction of sub-cellular localization by combining evolutionary and structural information. Proteins 2003 1.61
40 Protein-protein interactions more conserved within species than across species. PLoS Comput Biol 2006 1.61
41 Protein flexibility and rigidity predicted from sequence. Proteins 2005 1.58
42 NORSp: Predictions of long regions without regular secondary structure. Nucleic Acids Res 2003 1.58
43 Novel leverage of structural genomics. Nat Biotechnol 2007 1.57
44 Inferring sub-cellular localization through automated lexical analysis. Bioinformatics 2002 1.55
45 Structural genomics is the largest contributor of novel structural leverage. J Struct Funct Genomics 2009 1.52
46 Beyond annotation transfer by homology: novel protein-function prediction methods to assist drug discovery. Drug Discov Today 2005 1.46
47 Natively unstructured regions in proteins identified from contact predictions. Bioinformatics 2007 1.45
48 PEP: Predictions for Entire Proteomes. Nucleic Acids Res 2003 1.39
49 CASP6 assessment of contact prediction. Proteins 2005 1.39
50 Protein disorder--a breakthrough invention of evolution? Curr Opin Struct Biol 2011 1.37
51 Identifying cysteines and histidines in transition-metal-binding sites using support vector machines and neural networks. Proteins 2006 1.35
52 Target space for structural genomics revisited. Bioinformatics 2002 1.32
53 Solution NMR structure of the NlpC/P60 domain of lipoprotein Spr from Escherichia coli: structural evidence for a novel cysteine peptidase catalytic triad. Biochemistry 2008 1.27
54 Crystal structure of a potassium ion transporter, TrkH. Nature 2011 1.25
55 Homologue structure of the SLAC1 anion channel for closing stomata in leaves. Nature 2010 1.22
56 Sequence-based prediction of protein domains. Nucleic Acids Res 2004 1.21
57 CHOP proteins into structural domain-like fragments. Proteins 2004 1.21
58 DSSPcont: Continuous secondary structure assignments for proteins. Nucleic Acids Res 2003 1.20
59 Comparisons of NMR spectral quality and success in crystallization demonstrate that NMR and X-ray crystallography are complementary methods for small protein structure determination. J Am Chem Soc 2005 1.19
60 Natively unstructured loops differ from other loops. PLoS Comput Biol 2007 1.19
61 LOC3D: annotate sub-cellular localization for protein structures. Nucleic Acids Res 2003 1.18
62 Membrane protein prediction methods. Methods 2007 1.17
63 SNPdbe: constructing an nsSNP functional impacts database. Bioinformatics 2011 1.16
64 Better prediction of functional effects for sequence variants. BMC Genomics 2015 1.16
65 MetalDetector: a web server for predicting metal-binding sites and disulfide bridges in proteins from sequence. Bioinformatics 2008 1.15
66 Structural genomics target selection for the New York consortium on membrane protein structure. J Struct Funct Genomics 2009 1.14
67 LOCnet and LOCtarget: sub-cellular localization for structural genomics targets. Nucleic Acids Res 2004 1.12
68 LocTree2 predicts localization for all domains of life. Bioinformatics 2012 1.11
69 State-of-the-art in membrane protein prediction. Appl Bioinformatics 2002 1.11
70 Protein subcellular localization prediction using artificial intelligence technology. Methods Mol Biol 2008 1.09
71 Improving fold recognition without folds. J Mol Biol 2004 1.09
72 News from the protein mutability landscape. J Mol Biol 2013 1.08
73 The New York Consortium on Membrane Protein Structure (NYCOMPS): a high-throughput platform for structural genomics of integral membrane proteins. J Struct Funct Genomics 2010 1.07
74 Automated identification of complementarity determining regions (CDRs) reveals peculiar characteristics of CDRs and B cell epitopes. J Immunol 2008 1.05
75 Coordinating the impact of structural genomics on the human α-helical transmembrane proteome. Nat Struct Mol Biol 2013 1.05
76 Crystal structure of a phosphorylation-coupled saccharide transporter. Nature 2011 1.05
77 Static benchmarking of membrane helix predictions. Nucleic Acids Res 2003 1.05
78 Protein folding rates estimated from contact predictions. J Mol Biol 2005 1.03
79 Secondary structure assignment. Methods Biochem Anal 2003 1.02
80 NLProt: extracting protein names and sequences from papers. Nucleic Acids Res 2004 1.02
81 Towards big data science in the decade ahead from ten years of InCoB and the 1st ISCB-Asia Joint Conference. BMC Bioinformatics 2011 1.02
82 Large-scale analysis of thermostable, mammalian proteins provides insights into the intrinsically disordered proteome. J Proteome Res 2009 1.02
83 PROFtmb: a web server for predicting bacterial transmembrane beta barrel proteins. Nucleic Acids Res 2006 1.01
84 Protein secondary structure appears to be robust under in silico evolution while protein disorder appears not to be. Bioinformatics 2010 0.98
85 Structural genomics plucks high-hanging membrane proteins. Curr Opin Struct Biol 2012 0.98
86 NMPdb: Database of Nuclear Matrix Proteins. Nucleic Acids Res 2005 0.98
87 CHOP: parsing proteins into structural domains. Nucleic Acids Res 2004 0.98
88 Correlating protein function and stability through the analysis of single amino acid substitutions. BMC Bioinformatics 2009 0.97
89 Structural elucidation of the Cys-His-Glu-Asn proteolytic relay in the secreted CHAP domain enzyme from the human pathogen Staphylococcus saprophyticus. Proteins 2009 0.97
90 Cataloging proteins in cell cycle control. Methods Mol Biol 2004 0.96
91 ISCB computational biology Wikipedia competition. PLoS Comput Biol 2013 0.96
92 MuD: an interactive web server for the prediction of non-neutral substitutions using protein structural data. Nucleic Acids Res 2010 0.96
93 Disease-related mutations predicted to impact protein function. BMC Genomics 2012 0.96
94 In silico mutagenesis: a case study of the melanocortin 4 receptor. FASEB J 2009 0.96
95 CAFASP3 in the spotlight of EVA. Proteins 2003 0.95
96 Physical protein-protein interactions predicted from microarrays. Bioinformatics 2008 0.94
97 ISCB public policy statement on open access to scientific and technical research literature. Bioinformatics 2011 0.93
98 ISCB Public Policy Statement on Open Access to Scientific and Technical Research Literature. PLoS Comput Biol 2011 0.93
99 Structural basis of O6-alkylguanine recognition by a bacterial alkyltransferase-like DNA repair protein. J Biol Chem 2010 0.92
100 Transmembrane domains in the functions of Fc receptors. Biophys Chem 2003 0.92
101 Structural genomics reveals EVE as a new ASCH/PUA-related domain. Proteins 2009 0.92
102 Homology-based inference sets the bar high for protein function prediction. BMC Bioinformatics 2013 0.91
103 Cloud prediction of protein structure and function with PredictProtein for Debian. Biomed Res Int 2013 0.91
104 Powerful fusion: PSI-BLAST and consensus sequences. Bioinformatics 2008 0.91
105 Neutral and weakly nonneutral sequence variants may define individuality. Proc Natl Acad Sci U S A 2013 0.91
106 Alternative protein-protein interfaces are frequent exceptions. PLoS Comput Biol 2012 0.90
107 Solution NMR structure of the SOS response protein YnzC from Bacillus subtilis. Proteins 2008 0.90
108 LocDB: experimental annotations of localization for Homo sapiens and Arabidopsis thaliana. Nucleic Acids Res 2010 0.89
109 Predict impact of single amino acid change upon protein structure. BMC Genomics 2012 0.89
110 Using genetic algorithms to select most predictive protein features. Proteins 2009 0.88
111 Long membrane helices and short loops predicted less accurately. Protein Sci 2002 0.88
112 Large-scale experimental studies show unexpected amino acid effects on protein expression and solubility in vivo in E. coli. Microb Inform Exp 2011 0.88
113 EVAcon: a protein contact prediction evaluation service. Nucleic Acids Res 2005 0.86
114 An estimated 5% of new protein structures solved today represent a new Pfam family. Acta Crystallogr D Biol Crystallogr 2013 0.85
115 NMR and X-RAY structures of human E2-like ubiquitin-fold modifier conjugating enzyme 1 (UFC1) reveal structural and functional conservation in the metazoan UFM1-UBA5-UFC1 ubiquination pathway. J Struct Funct Genomics 2008 0.85
116 New in protein structure and function annotation: hotspots, single nucleotide polymorphisms and the 'Deep Web'. Curr Opin Drug Discov Devel 2009 0.85
117 Consensus sequences improve PSI-BLAST through mimicking profile-profile alignments. Nucleic Acids Res 2007 0.84
118 InCoB celebrates its tenth anniversary as first joint conference with ISCB-Asia. BMC Genomics 2011 0.84
119 Characterization of metalloproteins by high-throughput X-ray absorption spectroscopy. Genome Res 2011 0.84
120 Solution NMR structure of the 30S ribosomal protein S28E from Pyrococcus horikoshii. Protein Sci 2003 0.84
121 META-PP: single interface to crucial prediction servers. Nucleic Acids Res 2003 0.84
122 The 2.35 A structure of the TenA homolog from Pyrococcus furiosus supports an enzymatic function in thiamine metabolism. Acta Crystallogr D Biol Crystallogr 2005 0.83
123 Solution structure of Archaeglobus fulgidis peptidyl-tRNA hydrolase (Pth2) provides evidence for an extensive conserved family of Pth2 enzymes in archea, bacteria, and eukaryotes. Protein Sci 2005 0.83
124 tagtog: interactive and text-mining-assisted annotation of gene mentions in PLOS full-text articles. Database (Oxford) 2014 0.83
125 Protein conformational flexibility prediction using machine learning. J Magn Reson 2008 0.81
126 Accelerating the Original Profile Kernel. PLoS One 2013 0.80
127 Solution NMR structure of Lin0431 protein from Listeria innocua reveals high structural similarity with domain II of bacterial transcription antitermination protein NusG. Proteins 2010 0.80
128 Bioinformatics predictions of localization and targeting. Methods Mol Biol 2010 0.80
129 Solution NMR structure of photosystem II reaction center protein Psb28 from Synechocystis sp. Strain PCC 6803. Proteins 2011 0.79
130 Evaluation of transmembrane helix predictions in 2014. Proteins 2015 0.79
131 Comparison of a molecular dynamics model with the X-ray structure of the N370S acid-beta-glucosidase mutant that causes Gaucher disease. Protein Eng Des Sel 2011 0.79
132 Online tools for predicting integral membrane proteins. Methods Mol Biol 2009 0.79
133 NMR structure of the peptidyl-tRNA hydrolase domain from Pseudomonas syringae expands the structural coverage of the hydrolysis domains of class 1 peptide chain release factors. Proteins 2008 0.79
134 Solution NMR structure of Escherichia coli ytfP expands the structural coverage of the UPF0131 protein domain family. Proteins 2007 0.78
135 Solution NMR structure of the ribosomal protein RP-L35Ae from Pyrococcus furiosus. Proteins 2012 0.77
136 NMR structure of lipoprotein YxeF from Bacillus subtilis reveals a calycin fold and distant homology with the lipocalin Blc from Escherichia coli. PLoS One 2012 0.77
137 (1)H, (13)C and (15)N assignments for the Archaeglobus fulgidis protein AF2095. J Biomol NMR 2004 0.76
138 Create and assess protein networks through molecular characteristics of individual proteins. Bioinformatics 2006 0.76
139 Solution NMR structures of proteins VPA0419 from Vibrio parahaemolyticus and yiiS from Shigella flexneri provide structural coverage for protein domain family PFAM 04175. Proteins 2010 0.75
140 NMR structure of protein YvyC from Bacillus subtilis reveals unexpected structural similarity between two PFAM families. Proteins 2009 0.75
141 Cell cycle kinases predicted from conserved biophysical properties. Proteins 2009 0.75
142 Neural networks predict protein structure and function. Methods Mol Biol 2008 0.75
143 ISMB 2008 Toronto. PLoS Comput Biol 2008 0.75
144 Paving the future: finding suitable ISMB venues. Bioinformatics 2012 0.75
145 Bioinformatics in structural genomics. Bioinformatics 2002 0.75
146 nala: text mining natural language mutation mentions. Bioinformatics 2017 0.75
147 Co-expression and co-localization of hub proteins and their partners are encoded in protein sequence. Mol Biosyst 2014 0.75
148 Corrigendum: A draft network of ligand-receptor-mediated multicellular signalling in human. Nat Commun 2016 0.75